Entrez Gene

Basic Information
Gene ID	2771
Name	GNAI2
Synonymous	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2;GNAI2;guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
Definition	GTP-binding regulatory protein Gi alpha-2 chain\|adenylate cyclase-inhibiting G alpha protein\|guanine nucleotide-binding protein G(i) subunit alpha-2\|guanine nucleotide-binding protein G(i), alpha-2 subunit
Position	3p21.31
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database

Regulation From TransFac database
Transcription Factors [Top]
IL-8(h):CXCR1(h) + G-alpha-i2(h) <==> IL-8(h):CXCR1(h):G-alpha-i2(h) (binding)
IL-8(h):CXCR2(h) + G-alpha-i2(h) <==> IL-8(h):CXCR2(h):G-alpha-i2(h) (binding)
CXCR1(h) + G-alpha-i2(h) <==> CXCR1(h):G-alpha-i2(h) (binding)
CXCR2(h) + G-alpha-i2(h) <==> CXCR2(h):G-alpha-i2(h) (binding)
G-alpha-i2(h) + ATP --> G-alpha-i2(h){pY} + ADP (phosphorylation)
IRS-1(h) + G-alpha-i2(h) <==> IRS-1(h):G-alpha-i2(h) (binding)
G-alpha-i2(h) + Striatin(h) + ER-alpha(h) <==> G-alpha-i2(h):Striatin(h):ER-alpha(h) (binding)
CB1(h) + G-alpha-i2(h) <==> CB1(h):G-alpha-i2(h) (binding)
G-alpha-i2(h) + I-MF(h) <==> G-alpha-i2(h):I-MF(h) (binding)
G-alpha-i2(h) + PLSCR1(h) <==> G-alpha-i2(h):PLSCR1(h) (binding)
GNAI2(h) --> G-alpha-i2(h) (expression).
GNAI2(h) --> G-alpha-i2(h) (expression).

Location (AA)	PTM type	Database
Post Translational Modification [Top]
2	N-myristoyl glycine (By similarity).	Swiss-Prot 53.0
3	S-palmitoyl cysteine (By similarity).	Swiss-Prot 53.0
179	ADP-ribosylarginine; by cholera toxin (Bysimilarity).	Swiss-Prot 53.0
352	ADP-ribosylcysteine; by pertussis toxin(By similarity).	Swiss-Prot 53.0

Transcription Factors [Top]