| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 2771 |
Name | GNAI2 |
Synonym | GIP|GNAI2B|H_LUCA15.1|H_LUCA16.1;guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2;GNAI2;guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 |
Definition | GTP-binding regulatory protein Gi alpha-2 chain|adenylate cyclase-inhibiting G alpha protein|guanine nucleotide-binding protein G(i) subunit alpha-2|guanine nucleotide-binding protein G(i), alpha-2 subunit |
Position | 3p21.31 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Diabetes pathways;Reactome;REACT:15380 |
Pathway | Muscarinic acetylcholine receptor 2 and 4 signaling pathway;PANTHER;P00043 |
Pathway | Toxoplasmosis;KEGG PATHWAY;hsa05145 |
Pathway | Metabotropic glutamate receptor group II pathway;PANTHER;P00040 |
Pathway | Melanogenesis;KEGG PATHWAY;hsa04916 |
Pathway | Opioid Signalling;Reactome;REACT:15295 |
Pathway | Axon guidance;KEGG PATHWAY;hsa04360 |
Pathway | Leukocyte transendothelial migration;KEGG PATHWAY;hsa04670 |
Pathway | Signaling by GPCR;Reactome;REACT:14797 |
Pathway | CXCR3-mediated signaling events;PID Curated;200150 |
Pathway | PI3 kinase pathway;PANTHER;P00048 |
Pathway | 5HT1 type receptor mediated signaling pathway;PANTHER;P04373 |
Pathway | Progesterone-mediated oocyte maturation;KEGG PATHWAY;hsa04914 |
Pathway | Thromboxane A2 receptor signaling;PID Curated;200069 |
Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway;PANTHER;P00026 |
Pathway | Chagas disease;KEGG PATHWAY;hsa05142 |
Pathway | Gap junction;KEGG PATHWAY;hsa04540 |
Pathway | Hemostasis;Reactome;REACT:604 |
Pathway | Integration of energy metabolism;Reactome;REACT:1505 |
Pathway | Chemokine signaling pathway;KEGG PATHWAY;hsa04062 |
Pathway | Tight junction;KEGG PATHWAY;hsa04530 |
Pathway | Long-term depression;KEGG PATHWAY;hsa04730 |
Pathway | Gastric acid secretion;KEGG PATHWAY;hsa04971 |
Disease | Pituitary ACTH-secreting adenoma;OMIM |
Disease | Cancers;KEGG DISEASE |
Disease | Diabetes mellitus;FunDO |
Disease | Adrenal carcinoma;KEGG DISEASE;H00033 |
Disease | CARDIOVASCULAR;GAD |
Disease | Cancers of endocrine organs;KEGG DISEASE |
Disease | Ventricular tachycardia, idiopathic;OMIM |
Disease | blood pressure, arterial;GAD |
External Links | |
Links to Entrez Gene | 2771 |
Links to all GeneRIF Items | 2771 |
Links to iHOP | 2771 |
Sequence Information | |
Nucleotide Sequence | >2771 : length: 2591 ACTGCAAGCTCCGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTG GGACTACAGGCGCCCGCTACCGCGCCCGGCTAATTTTTTGTATTTTTAATAGAGACGGGG TTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCGCCCGCCTTGGC CTCCCAGAGTGCTGGGATGACAGGCGTGAGCCTCTGAGAGCAAATTTTACCCAGTTCCTC TCTATCCTCCCGATGACTCTGAAATCAAACTCAGCAAGTCATCCGAGCCCCCACGGCGCA GCGGCCCTAGGCTGGCATGGGCGATGCGGAGCTACTCCGCCCTCAGGAAGCAGGCGAGGT GCCCAGCGGGAGAATCACCCACATCACCGTCTAATCTCTGCTGTGAAGTGGAAGCGCGAG AAGGAGGGAGCGTCTCATGACGGAGGGTGTGAAGACGCTAGGCTGGACGAAGCAGAAAGG CGGGTGTCACTGGGGACGTTCTGAGGGCCCCTGGTTGCTAAGGCTCAGTGTGGGGAGAAG AAGGGCTGCTACCCTGTTGGATGGAGTATGCAGGGCATCTTCCTGCCAGCTCTGCCCAGG GCACCATATTGGCATGCACCAGCTGCACAGGTGCTGGGGAGTCAGGGAAGAGCACCATCG TCAAGCAGATGAAGATCATCCACGAGGATGGCTACTCCGAGGAGGAATGCCGGCAGTACC GGGCGGTTGTCTACAGCAACACCATCCAGTCCATCATGGCCATTGTCAAAGCCATGGGCA ACCTGCAGATCGACTTTGCCGACCCCTCCAGAGCGGACGACGCCAGGCAGCTATTTGCAC TGTCCTGCACCGCCGAGGAGCAAGGCGTGCTCCCTGATGACCTGTCCGGCGTCATCCGGA GGCTCTGGGCTGACCATGGTGTGCAGGCCTGCTTTGGCCGCTCAAGGGAATACCAGCTCA ACGACTCAGCTGCCTACTACCTGAACGACCTGGAGCGTATTGCACAGAGTGACTACATCC CCACACAGCAAGATGTGCTACGGACCCGCGTAAAGACCACGGGGATCGTGGAGACACACT TCACCTTCAAGGACCTACACTTCAAGATGTTTGATGTGGGTGGTCAGCGGTCTGAGCGGA AGAAGTGGATCCACTGCTTTGAGGGCGTCACAGCCATCATCTTCTGCGTAGCCTTGAGCG CCTATGACTTGGTGCTAGCTGAGGACGAGGAGATGAACCGCATGCATGAGAGCATGAAGC TATTCGATAGCATCTGCAACAACAAGTGGTTCACAGACACGTCCATCATCCTCTTCCTCA ACAAGAAGGACCTGTTTGAGGAGAAGATCACACACAGTCCCCTGACCATCTGCTTCCCTG AGTACACAGGGGCCAACAAATATGATGAGGCAGCCAGCTACATCCAGAGTAAGTTTGAGG ACCTGAATAAGCGCAAAGACACCAAGGAGATCTACACGCACTTCACGTGCGCCACCGACA CCAAGAACGTGCAGTTCGTGTTTGACGCCGTCACCGATGTCATCATCAAGAACAACCTGA AGGACTGCGGCCTCTTCTGAGGGGCAGCGGGGCCTGGCGGGATGGGCCACCGCCGACTTT GTACCCCCCAACCCCTGAGGAAGATGGGGGCAAGAAGATCACGCTCCCCGCCTGTTCCCC CGCCGCTTTTCTCCTCTTTCCTCTCTTTGTTCTCAGCTCCCCCTGTCCCCTCAGCTCCAG ACGTAGGGGAGGGGTTGCCACAGGCCTCCCTGTTTGAAGCCTGCCCTTGTCTGAGATGCT GGTAATGGCCATGGTACCCCCTTCTGGGCATCTGTTCTGGTTTTTAACCATTGTCTTGTT CTGTGATGAGGGGAGGGGGGCACATGCTGAGTCTCCCAAGGCTGCGTCTGGAGGGGCCCC TGCTTCTCCAGCCTGGACCCCCAGCTTTGCCCAACACCAGCCCCTGCCCCAGCCCAAGTC CAAATGTTTACAGGGAGCCTCCTGCCCAGTCCCCCAACCCCAGCCGCTCGGAGGCCCCAA AGGAAAAAGCACAAGAAGCGTGAGACGCCACCATTCCTGGAAACCACAGTCCACCTGCTC ATTCTCGTAGCTTTTTAAAAAAATGAAAGTAAAGGAAAAAAAAAAAACTGCAAATCTAGA AAACTTTTTAGAGAAAAACTATTTAAAACTGTCAGATCCTGACCAGCAAGCCCCCCCCCA GCCCCCCTTCCAAGTGACTCCGTGCCTTGAGTGTGTCTGCGTGTTTACACCCGTCCCTCT GCTGGCCGCCCCCGTGCGAGCGGCACCCCTGCCCTGCCCTCCACAGAATTGGGTTCCAAG GGCTGTTCCAGACAACTGCCAACGTCACTGAGGGCCCTGCCCCAGCGGCCCTGGCCCCAG GCTCTATTAACCTAAAATGTAGCTCCCTAGCGCTAACCTAGGAACCGCCGCTGCCTGCTG GGGGGCCACGCCCCTCATGCCCTTGTCCCAGGCCCGGGGCCTTCAGCGTTGAACACTTCC TTGCTTTTTTCACATGTTTTATGGAATTGTTCACCTGGTTTGAAATAATAAAATGTAGAA AGAAAAAAAAT |
Protein Sequence | >2771 : length: 355 MGCTVSAEDKAAAERSKMIDKNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEDG YSEEECRQYRAVVYSNTIQSIMAIVKAMGNLQIDFADPSRADDARQLFALSCTAEEQGVL PDDLSGVIRRLWADHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRV KTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEE MNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKITHSPLTICFPEYTGANKYDEA ASYIQSKFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF |