| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 2214 |
Name | FCGR3A |
Synonymous | Fc fragment of IgG, low affinity IIIa, receptor (CD16a);FCGR3A;Fc fragment of IgG, low affinity IIIa, receptor (CD16a) |
Definition | CD16a antigen|Fc fragment of IgG, low affinity III, receptor for (CD16)|Fc gamma receptor III-A|Fc-gamma RIII-alpha|Fc-gamma RIIIa|Fc-gamma receptor III-2 (CD 16)|Fc-gamma receptor IIIb (CD16)|FcgammaRIIIA|fc-gamma RIII|igG Fc receptor III-2|immunoglobuli |
Position | 1q23 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | FCgammaRIIIA(h) + IgG1(h) <==> FCgammaRIIIA(h):IgG1(h) (binding) | FCgammaRIIIA(h) --> IL-6(h) (decrease of secretion) | FCgammaRIIIA(h) --> IL-13(h) (decrease of secretion) | FCgammaRIIIA(h) --> TNF-alpha(h) (decrease of secretion) | FCgammaRIIIA(h) --> MCP-1(h) (decrease of secretion) | FCGR3A(h) --> FCgammaRIIIA(h) (expression). | FCGR3A(h) --> FCgammaRIIIA(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 56 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 63 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 92 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 180 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 187 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr1 |
Promoter: 159785942 - 159787942 | GSE27584 |
chr1 |
Promoter: 159785942 - 159787942 | E-GEOD-20553 |