Cancer metastasis gene database Home
Cancer metastasis database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

1378

Name

CR1

Synonymous

complement component (3b/4b) receptor 1 (Knops blood group);CR1;complement component (3b/4b) receptor 1 (Knops blood group)

Definition

C3-binding protein|C3b/C4b receptor|CD35 antigen|Knops blood group antigen|complement receptor type 1

Position

1q32

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

complement C3(h) + CD35(h) <==> complement C3(h):CD35(h) (binding)
C1Q(h) + CD35(h) <==> C1Q(h):CD35(h) (binding)
CD35(h) + (complement C3(h))2 <==> CD35(h):(complement C3(h))2 (binding)
C1Q(m.s.) + CD35(h) <==> C1Q(m.s.):CD35(h) (binding)
MBL(h) + CD35(h) <==> MBL(h):CD35(h) (binding)
CD35(h) + (C4F(h))2 <==> CD35(h):(C4F(h))2 (binding)
C4F(m.s.) + CD35(h) <==> C4F(m.s.):CD35(h) (binding)
CD35(h) + C4F(h) <==> CD35(h):C4F(h) (binding)
C4(h) + CD35(h) <==> C4(h):CD35(h) (binding)
C4S(h) + CD35(h) <==> C4S(h):CD35(h) (binding)
CD35(h) + GP63(LEIMA) <==> CD35(h):GP63(LEIMA) (binding)
CR1(h) --> CD35(h) (expression).
MBL(h) + CD35(h) <==> MBL(h):CD35(h) (binding)
CD35(h) + (C4F(h))2 <==> CD35(h):(C4F(h))2 (binding)
C4F(m.s.) + CD35(h) <==> C4F(m.s.):CD35(h) (binding)
complement C3(h) + CD35(h) <==> complement C3(h):CD35(h) (binding)
CD35(h) + (complement C3(h))2 <==> CD35(h):(complement C3(h))2 (binding)
C1Q(h) + CD35(h) <==> C1Q(h):CD35(h) (binding)
complement C3(h):BF(m.s.) + CD35(h) <==> complement C3(h):BF(m.s.):CD35(h) (binding)
CO2(h):C4F(h) + CD35(h) <==> CO2(h):C4F(h):CD35(h) (binding)
CD35(h) + ATP --> CD35(h){p} + ADP (phosphorylation)
CR1(h) --> CD35(h) (expression).

Post Translational Modification   [Top]

Location (AA)

PTM type

Literature

Database

42Pyrrolidone carboxylic acid (Potential).Swiss-Prot 53.0
56N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
252N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
410N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
447N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
509N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
578N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
702N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
860N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
897N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
959N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1028N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1152N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1310N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1481N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1504N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1534N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1540N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1605N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1763N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1908N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr1

Promoter: 205734596 - 205736596GSE27584

chr1

Promoter: 205734596 - 205736596GSE27584