| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 1378 |
Name | CR1 |
Synonymous | complement component (3b/4b) receptor 1 (Knops blood group);CR1;complement component (3b/4b) receptor 1 (Knops blood group) |
Definition | C3-binding protein|C3b/C4b receptor|CD35 antigen|Knops blood group antigen|complement receptor type 1 |
Position | 1q32 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | complement C3(h) + CD35(h) <==> complement C3(h):CD35(h) (binding) | C1Q(h) + CD35(h) <==> C1Q(h):CD35(h) (binding) | CD35(h) + (complement C3(h))2 <==> CD35(h):(complement C3(h))2 (binding) | C1Q(m.s.) + CD35(h) <==> C1Q(m.s.):CD35(h) (binding) | MBL(h) + CD35(h) <==> MBL(h):CD35(h) (binding) | CD35(h) + (C4F(h))2 <==> CD35(h):(C4F(h))2 (binding) | C4F(m.s.) + CD35(h) <==> C4F(m.s.):CD35(h) (binding) | CD35(h) + C4F(h) <==> CD35(h):C4F(h) (binding) | C4(h) + CD35(h) <==> C4(h):CD35(h) (binding) | C4S(h) + CD35(h) <==> C4S(h):CD35(h) (binding) | CD35(h) + GP63(LEIMA) <==> CD35(h):GP63(LEIMA) (binding) | CR1(h) --> CD35(h) (expression). | MBL(h) + CD35(h) <==> MBL(h):CD35(h) (binding) | CD35(h) + (C4F(h))2 <==> CD35(h):(C4F(h))2 (binding) | C4F(m.s.) + CD35(h) <==> C4F(m.s.):CD35(h) (binding) | complement C3(h) + CD35(h) <==> complement C3(h):CD35(h) (binding) | CD35(h) + (complement C3(h))2 <==> CD35(h):(complement C3(h))2 (binding) | C1Q(h) + CD35(h) <==> C1Q(h):CD35(h) (binding) | complement C3(h):BF(m.s.) + CD35(h) <==> complement C3(h):BF(m.s.):CD35(h) (binding) | CO2(h):C4F(h) + CD35(h) <==> CO2(h):C4F(h):CD35(h) (binding) | CD35(h) + ATP --> CD35(h){p} + ADP (phosphorylation) | CR1(h) --> CD35(h) (expression). |
|---|
Post Translational Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 42 | Pyrrolidone carboxylic acid (Potential). | Swiss-Prot 53.0 | 56 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 252 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 410 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 447 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 509 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 578 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 702 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 860 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 897 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 959 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 1028 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 1152 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 1310 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 1481 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 1504 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 1534 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 1540 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 1605 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 1763 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 1908 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr1 |
Promoter: 205734596 - 205736596 | GSE27584 |
chr1 |
Promoter: 205734596 - 205736596 | GSE27584 |