Entrez Gene

Basic Information
Gene ID	11059
Name	WWP1
Synonymous	WW domain containing E3 ubiquitin protein ligase 1;WWP1;WW domain containing E3 ubiquitin protein ligase 1
Definition	NEDD4-like E3 ubiquitin-protein ligase WWP1\|Nedd-4-like ubiquitin-protein ligase\|TGIF-interacting ubiquitin ligase 1\|WW domain-containing protein 1\|atrophin-1 interacting protein 5\|atrophin-1-interacting protein 5
Position	8q21
Gene Type	protein-coding
Gene Regulation:	Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database

Regulation From TransFac database
Transcription Factors [Top]
atrophin-1(m.s.) + AIP5(h) <==> atrophin-1(m.s.):AIP5(h) (binding)
AIP5(h) + RasGAP(h) <==> AIP5(h):RasGAP(h) (binding)
AIP5(h) + CLCN5(h) <==> AIP5(h):CLCN5(h) (binding)
AIP5(h) + AP-2alpha(h) <==> AIP5(h):AP-2alpha(h) (binding)
AIP5(h) + Smad7(m) <==> AIP5(h):Smad7(m) (regulation of localization; binding)
AIP5(h) + Smad6(m.s.) <==> AIP5(h):Smad6(m.s.) (binding)
AIP5(h) + Smad2(m.s.) <==> AIP5(h):Smad2(m.s.) (binding)
AIP5(h) + Smad3(m.s.) <==> AIP5(h):Smad3(m.s.) (binding)
AIP5(h) + Smad7(h) <==> AIP5(h):Smad7(h) (binding)
AIP5(h) --> Smad7(m) (binding)
AIP5(h) --> TGFbetaR-I(m.s.) (binding)
EWS(h) + AIP5(h) <==> EWS(h):AIP5(h) (binding)
dazap2(h) + AIP5(h) <==> dazap2(h):AIP5(h) (binding)
CFIM68(h) + AIP5(h) <==> CFIM68(h):AIP5(h) (binding)
AIP5(h) + ZFML(h) <==> AIP5(h):ZFML(h) (binding)
WWP1(h) --> AIP5(h) (expression).
TGFbetaR-I(m.s.) + ubiquitin(v.s.) --AIP5(h)--> TGFbetaR-I(m.s.){ub} (ubiquitination)
Smad6(m.s.) + ubiquitin(v.s.) --AIP5(h)--> Smad6(m.s.){ub} (ubiquitination)
Smad7(m) + ubiquitin(v.s.) --AIP5(h)--> Smad7(m){ub} (ubiquitination)

Location (AA)	PTM type	Literature	Database
Post Translational Modification [Top]
822	Phosphothreonine.		Swiss-Prot 53.0

Transcription Factors [Top]