Entrez Gene

Basic Information
Gene ID	11059
Name	WWP1
Synonymous	WW domain containing E3 ubiquitin protein ligase 1;WWP1;WW domain containing E3 ubiquitin protein ligase 1
Definition	NEDD4-like E3 ubiquitin-protein ligase WWP1\|Nedd-4-like ubiquitin-protein ligase\|TGIF-interacting ubiquitin ligase 1\|WW domain-containing protein 1\|atrophin-1 interacting protein 5\|atrophin-1-interacting protein 5
Position	8q21
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.926G>T; p.S309I; 8:86411739-86411739	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.349G>T; p.E117*; 8:86398356-86398356	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.2468G>A; p.R823K; 8:86457994-86457994	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1463G>T; p.R488I; 8:86431481-86431481	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1243G>T; p.E415*; 8:86427728-86427728	central_nervous_system; cerebrum	glioma; astrocytoma_Grade_IV	Substitution - Nonsense
c.1243G>T; p.E415*; 8:86427728-86427728	central_nervous_system; brain	glioma	Substitution - Nonsense
c.315G>A; p.L105L; 8:86381610-86381610	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.803C>T; p.A268V; 8:86411616-86411616	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.268G>A; p.A90T; 8:86381563-86381563	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.153G>A; p.T51T; 8:86380808-86380808	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1382G>A; p.G461D; 8:86430746-86430746	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1243G>A; p.E415K; 8:86427728-86427728	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1014T>C; p.P338P; 8:86411827-86411827	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.1797_1801delATTTA; p.I599fs*7; 8:86438632-86438636	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Deletion - Frameshift
c.1996A>G; p.M666V; 8:86442776-86442776	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.816T>G; p.N272K; 8:86411629-86411629	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1702A>C; p.K568Q; 8:86435657-86435657	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.276_277insT; p.L93fs*18; 8:86381571-86381572	liver	carcinoma; hepatocellular_carcinoma	Insertion - Frameshift
c.1118G>A; p.R373Q; 8:86425279-86425279	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1118G>A; p.R373Q; 8:86425279-86425279	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1118G>A; p.R373Q; 8:86425279-86425279	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.61C>G; p.Q21E; 8:86374111-86374111	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.152C>T; p.T51M; 8:86380807-86380807	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2456G>A; p.R819Q; 8:86457982-86457982	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.975A>T; p.E325D; 8:86411788-86411788	liver	carcinoma	Substitution - Missense
c.975A>T; p.E325D; 8:86411788-86411788	liver	carcinoma	Substitution - Missense
c.1062-1G>A; p.?; 8:86425222-86425222	breast	carcinoma	Unknown
c.257G>A; p.R86H; 8:86381552-86381552	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.257G>A; p.R86H; 8:86381552-86381552	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.257G>A; p.R86H; 8:86381552-86381552	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2470A>G; p.N824D; 8:86457996-86457996	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; follicular_lymphoma	Substitution - Missense
c.257G>A; p.R86H; 8:86381552-86381552	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1331C>T; p.S444L; 8:86427816-86427816	prostate	carcinoma	Substitution - Missense
c.751C>G; p.P251A; 8:86411564-86411564	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1242G>T; p.M414I; 8:86427727-86427727	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1784G>A; p.R595H; 8:86438619-86438619	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.911_915delAATCT; p.E304fs*3; 8:86411724-86411728	endometrium	carcinoma; endometrioid_carcinoma	Deletion - Frameshift
c.516G>A; p.E172E; 8:86398615-86398615	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2358T>C; p.L786L; 8:86452643-86452643	bone; femur	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.947C>G; p.S316C; 8:86411760-86411760	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.163A>C; p.K55Q; 8:86380818-86380818	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.163A>C; p.K55Q; 8:86380818-86380818	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2545T>C; p.F849L; 8:86461269-86461269	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.249G>T; p.W83C; 8:86381544-86381544	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1431T>C; p.H477H; 8:86431449-86431449	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.4G>A; p.A2T; 8:86374054-86374054	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4G>A; p.A2T; 8:86374054-86374054	prostate	carcinoma	Substitution - Missense
c.994C>A; p.P332T; 8:86411807-86411807	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2718delG; p.E907fs*7; 8:86466842-86466842	skin; face	malignant_melanoma	Deletion - Frameshift
c.614C>T; p.S205L; 8:86402093-86402093	skin	malignant_melanoma	Substitution - Missense
c.283_284GG>CT; p.G95L; 8:86381578-86381579	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.616T>A; p.Y206N; 8:86402095-86402095	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1057T>G; p.S353A; 8:86411870-86411870	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.464C>T; p.S155F; 8:86398471-86398471	bone; femur	chondrosarcoma	Substitution - Missense
c.2291G>A; p.R764H; 8:86452576-86452576	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2365C>A; p.L789I; 8:86452650-86452650	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2365C>A; p.L789I; 8:86452650-86452650	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2520T>C; p.N840N; 8:86461244-86461244	bone; fibula	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.2365C>A; p.L789I; 8:86452650-86452650	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1188A>T; p.R396S; 8:86427673-86427673	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1790A>G; p.Y597C; 8:86438625-86438625	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1279C>T; p.R427W; 8:86427764-86427764	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.275_276insT; p.L93fs*18; 8:86381570-86381571	liver	carcinoma	Insertion - Frameshift
c.1073G>T; p.R358I; 8:86425234-86425234	breast	carcinoma	Substitution - Missense
c.1073G>T; p.R358I; 8:86425234-86425234	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1117C>T; p.R373*; 8:86425278-86425278	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1180C>T; p.R394C; 8:86427665-86427665	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1523G>A; p.R508H; 8:86431665-86431665	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2701A>G; p.S901G; 8:86466825-86466825	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.264A>T; p.L88F; 8:86381559-86381559	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.764C>T; p.A255V; 8:86411577-86411577	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2503G>A; p.V835M; 8:86461227-86461227	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1475T>G; p.L492*; 8:86431617-86431617	thyroid	other; neoplasm	Substitution - Nonsense
c.1413G>T; p.R471S; 8:86431431-86431431	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1635C>T; p.R545R; 8:86435485-86435485	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - coding silent
c.1200G>T; p.V400V; 8:86427685-86427685	lung	carcinoma; small_cell_carcinoma	Substitution - coding silent
c.2299C>T; p.R767*; 8:86452584-86452584	breast	carcinoma	Substitution - Nonsense
c.2023G>A; p.D675N; 8:86448172-86448172	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2548G>C; p.V850L; 8:86461272-86461272	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1018C>T; p.R340W; 8:86411831-86411831	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.806T>G; p.L269W; 8:86411619-86411619	skin	malignant_melanoma	Substitution - Missense
c.154A>G; p.K52E; 8:86380809-86380809	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.578T>C; p.V193A; 8:86402057-86402057	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.214G>A; p.V72I; 8:86381509-86381509	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.265A>G; p.K89E; 8:86381560-86381560	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.844C>A; p.P282T; 8:86411657-86411657	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.649C>T; p.P217S; 8:86402128-86402128	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1835C>T; p.A612V; 8:86438670-86438670	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1257T>G; p.N419K; 8:86427742-86427742	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2034C>A; p.F678L; 8:86448183-86448183	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.979G>A; p.A327T; 8:86411792-86411792	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2455C>T; p.R819*; 8:86457981-86457981	prostate	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2547C>T; p.F849F; 8:86461271-86461271	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1280G>A; p.R427Q; 8:86427765-86427765	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1163A>G; p.E388G; 8:86427648-86427648	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1951C>G; p.P651A; 8:86442731-86442731	ovary	other; neoplasm	Substitution - Missense
c.2030G>A; p.G677D; 8:86448179-86448179	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.2468G>C; p.R823T; 8:86457994-86457994	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; follicular_lymphoma	Substitution - Missense
c.1472+1G>A; p.?; 8:86431491-86431491	lung	carcinoma; adenocarcinoma	Unknown
c.896C>G; p.T299S; 8:86411709-86411709	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2008C>T; p.H670Y; 8:86448157-86448157	breast	carcinoma	Substitution - Missense
c.1049C>T; p.T350I; 8:86411862-86411862	skin	malignant_melanoma	Substitution - Missense
c.1247C>T; p.S416F; 8:86427732-86427732	skin	malignant_melanoma	Substitution - Missense
c.293C>T; p.T98M; 8:86381588-86381588	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1443A>C; p.T481T; 8:86431461-86431461	central_nervous_system; brain	glioma	Substitution - coding silent
c.2456G>C; p.R819P; 8:86457982-86457982	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1985G>A; p.R662H; 8:86442765-86442765	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.2313A>G; p.E771E; 8:86452598-86452598	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.223C>T; p.Q75*; 8:86381518-86381518	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1061+1G>T; p.?; 8:86411875-86411875	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.744A>C; p.S248S; 8:86411557-86411557	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.2167_2182del16; p.Y723fs*12; 8:86448407-86448422	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Deletion - Frameshift
c.1342T>C; p.L448L; 8:86430706-86430706	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2133A>G; p.R711R; 8:86448373-86448373	breast	carcinoma	Substitution - coding silent
c.1366G>T; p.G456*; 8:86430730-86430730	urinary_tract; bladder	carcinoma	Substitution - Nonsense
c.1798T>G; p.F600V; 8:86438633-86438633	liver	carcinoma	Substitution - Missense
c.25G>C; p.D9H; 8:86374075-86374075	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1798T>G; p.F600V; 8:86438633-86438633	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.132A>T; p.V44V; 8:86380787-86380787	liver	carcinoma	Substitution - coding silent
c.1720C>T; p.Q574*; 8:86435675-86435675	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.132A>T; p.V44V; 8:86380787-86380787	liver	carcinoma	Substitution - coding silent
c.2098G>A; p.D700N; 8:86448247-86448247	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.726T>A; p.V242V; 8:86411539-86411539	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.611G>A; p.C204Y; 8:86402090-86402090	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2149G>T; p.E717*; 8:86448389-86448389	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.860T>C; p.L287P; 8:86411673-86411673	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1634G>A; p.R545H; 8:86435484-86435484	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.219G>A; p.T73T; 8:86381514-86381514	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.363T>A; p.L121L; 8:86398370-86398370	skin	malignant_melanoma	Substitution - coding silent
c.1038C>T; p.A346A; 8:86411851-86411851	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2509G>T; p.E837*; 8:86461233-86461233	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.2336G>A; p.G779D; 8:86452621-86452621	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1888T>A; p.L630I; 8:86442668-86442668	liver	carcinoma	Substitution - Missense
c.1960C>G; p.L654V; 8:86442740-86442740	breast	carcinoma	Substitution - Missense
c.179C>G; p.S60C; 8:86380834-86380834	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.782C>T; p.P261L; 8:86411595-86411595	liver	carcinoma	Substitution - Missense
c.108C>T; p.F36F; 8:86380763-86380763	skin	malignant_melanoma	Substitution - coding silent
c.108C>T; p.F36F; 8:86380763-86380763	skin	malignant_melanoma	Substitution - coding silent
c.1472+1G>T; p.?; 8:86431491-86431491	stomach	carcinoma; adenocarcinoma	Unknown
c.1840G>A; p.E614K; 8:86442620-86442620	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1357G>T; p.D453Y; 8:86430721-86430721	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.178T>G; p.S60A; 8:86380833-86380833	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.2242G>A; p.V748M; 8:86448482-86448482	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2340T>C; p.F780F; 8:86452625-86452625	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2453A>G; p.Y818C; 8:86457979-86457979	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1037C>T; p.A346V; 8:86411850-86411850	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2217G>A; p.L739L; 8:86448457-86448457	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.708G>C; p.E236D; 8:86402187-86402187	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.2725_2727delCTT; p.L910delL; 8:86466849-86466851	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - In frame
c.99G>T; p.K33N; 8:86380754-86380754	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.38A>G; p.N13S; 8:86374088-86374088	ovary	other; neoplasm	Substitution - Missense
c.1549C>T; p.H517Y; 8:86431691-86431691	breast	carcinoma	Substitution - Missense
c.1100A>T; p.Y367F; 8:86425261-86425261	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.38A>G; p.N13S; 8:86374088-86374088	ovary	other; neoplasm	Substitution - Missense
c.1829G>A; p.G610D; 8:86438664-86438664	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.263T>A; p.L88*; 8:86381558-86381558	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1583G>A; p.R528H; 8:86431725-86431725	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1583G>A; p.R528H; 8:86431725-86431725	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.951T>C; p.N317N; 8:86411764-86411764	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.229A>G; p.T77A; 8:86381524-86381524	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1172T>C; p.V391A; 8:86427657-86427657	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1113T>C; p.N371N; 8:86425274-86425274	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.299A>T; p.D100V; 8:86381594-86381594	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1875C>A; p.N625K; 8:86442655-86442655	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2216T>C; p.L739P; 8:86448456-86448456	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2216T>C; p.L739P; 8:86448456-86448456	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2216T>C; p.L739P; 8:86448456-86448456	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.685G>A; p.A229T; 8:86402164-86402164	liver	carcinoma	Substitution - Missense
c.810T>A; p.S270S; 8:86411623-86411623	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.685G>A; p.A229T; 8:86402164-86402164	liver	carcinoma	Substitution - Missense
c.2207C>A; p.S736*; 8:86448447-86448447	skin	malignant_melanoma	Substitution - Nonsense
c.210-2A>G; p.?; 8:86381503-86381503	liver	carcinoma	Unknown
c.210-2A>G; p.?; 8:86381503-86381503	liver	carcinoma; hepatocellular_carcinoma	Unknown
c.354A>G; p.Q118Q; 8:86398361-86398361	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2179G>C; p.D727H; 8:86448419-86448419	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1923G>A; p.L641L; 8:86442703-86442703	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1228delC; p.Q410fs*39; 8:86427713-86427713	liver	carcinoma; hepatocellular_carcinoma	Deletion - Frameshift
c.1228delC; p.Q410fs*39; 8:86427713-86427713	liver	carcinoma	Deletion - Frameshift
c.1981G>A; p.G661S; 8:86442761-86442761	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1056A>G; p.P352P; 8:86411869-86411869	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.590C>T; p.T197I; 8:86402069-86402069	skin	malignant_melanoma	Substitution - Missense
c.1936G>A; p.A646T; 8:86442716-86442716	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1771G>T; p.D591Y; 8:86438606-86438606	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.830C>A; p.T277N; 8:86411643-86411643	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1184G>A; p.R395K; 8:86427669-86427669	skin	malignant_melanoma	Substitution - Missense

COSMIC somatic mutation [Top]