Cancer metastasis gene database Home
Cancer metastasis database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

11004

Name

KIF2C

Synonymous

kinesin family member 2C;KIF2C;kinesin family member 2C

Definition

kinesin-like protein 6|kinesin-like protein KIF2C|mitotic centromere-associated kinesin

Position

1p34.1

Gene Type

protein-coding

Gene Regulation:

Transcription Factors
Post Translational Modification From dbPTM
Methylation Profile From DiseaseMeth database

Transcription Factors   [Top]

Regulation From TransFac database

CENPH(h) + MCAK(h) <==> CENPH(h):MCAK(h) (binding)
MCAK(h) + ATP --Aurora-B(h)--> MCAK(h){pS92} + ADP (phosphorylation)
KIF2C(h) --> MCAK(h) (expression).
KIF2C(h) --> MCAK-isoform1(h) (expression).
KIF2C(h) --> MCAK-isoform2(h) (expression).

Post Translational Modification   [Top]

Location (AA)

PTM type

Literature

Database

628Phosphoserine.Swiss-Prot 53.0
629Phosphoserine.Swiss-Prot 53.0
632Phosphoserine.Swiss-Prot 53.0
633Phosphoserine.Swiss-Prot 53.0
95Phosphoserine (Aurora B)14960279Phospho.ELM 6.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr1

Promoter: 44976638 - 44978638Agilent_014791

chr1

Promoter: 44976638 - 44978638GSE27584