| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 10403 |
Name | NDC80 |
Synonymous | NDC80 kinetochore complex component;NDC80;NDC80 kinetochore complex component |
Definition | NDC80 homolog, kinetochore complex component|NDC80 kinetochore complex component homolog|highly expressed in cancer protein|highly expressed in cancer, rich in leucine heptad repeats|kinetochore associated 2|kinetochore protein Hec1|kinetochore protein ND |
Position | 18p11.32 |
Gene Type | protein-coding |
Gene Regulation: | Transcription Factors Post Translational Modification From dbPTM Methylation Profile From DiseaseMeth database |
Transcription Factors [Top] |
Regulation From TransFac database | Hec1(h) + Aurora-B(h) <==> Hec1(h):Aurora-B(h) (binding) | Hec1(h) + Nuf2(h) <==> Hec1(h):Nuf2(h) (binding) | 2 Hec1(h) <==> Hec1(h):Hec1(h) (binding; oligomerization) | Hec1(h) + ATP --Aurora-A(h)--> Hec1(h){p} + ADP (phosphorylation) | Hec1(h) + ATP --Aurora-B(h)--> Hec1(h){p} + ADP (phosphorylation) | Hec1(h) + Nek2A(h) <==> Hec1(h):Nek2A(h) (binding) | Hec1(h) + ATP --Nek2A(h)--> Hec1(h){pS165} + ADP (phosphorylation) | SMC1(h) + Hec1(h) <==> SMC1(h):Hec1(h) (binding) | S7(h) + Hec1(h) <==> S7(h):Hec1(h) (binding) | S8(h) + Hec1(h) <==> S8(h):Hec1(h) (binding) | Hec1(h) + pldn(h) <==> Hec1(h):pldn(h) (binding) | Hec1(h) + CGI-116(h) <==> Hec1(h):CGI-116(h) (binding) | Hec1(h) + LCCP(h) <==> Hec1(h):LCCP(h) (binding) | Hec1(h) + Cocoa(h) <==> Hec1(h):Cocoa(h) (binding) | Hec1(h) + KLHL12(h) <==> Hec1(h):KLHL12(h) (binding) | Hec1(h) + ushbp1(h) <==> Hec1(h):ushbp1(h) (binding) | Kntc2(h) --> Hec1(h) (expression). | H2O + ATP --S7(h)--> ADP + p (hydrolysis) | Nuf2(h) + Hec1(h) <==> Nuf2(h):Hec1(h) (binding) | Kntc2(h) --> Hec1(h) (expression). |
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Post Translational Modification [Top] | |||
There is no record for NDC80 | |||
Methylation Profile [Top] | ||
There is no record for NDC80 | ||