Cancer metastasis gene database Home
Cancer metastasis database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

941

Name

CD80

Synonymous

CD80 molecule;CD80;CD80 molecule

Definition

B-lymphocyte activation antigen B7|CD80 antigen (CD28 antigen ligand 1, B7-1 antigen)|CTLA-4 counter-receptor B7.1|T-lymphocyte activation antigen CD80|activation B7-1 antigen|costimulatory factor CD80|costimulatory molecule variant IgV-CD80

Position

3q13.3-q21

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.57C>G; p.F19L; 3:119557672-119557672

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.57C>G; p.F19L; 3:119557672-119557672

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.824G>A; p.R275K; 3:119527814-119527814

 skinmalignant_melanomaSubstitution - Missense

c.674T>C; p.V225A; 3:119537163-119537163

 large_intestine; rectumNSSubstitution - Missense

c.674T>C; p.V225A; 3:119537163-119537163

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.840G>A; p.L280L; 3:119527798-119527798

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.331G>A; p.E111K; 3:119544637-119544637

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.331G>A; p.E111K; 3:119544637-119544637

 skinmalignant_melanomaSubstitution - Missense

c.314C>A; p.A105D; 3:119544654-119544654

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.464C>A; p.S155Y; 3:119537373-119537373

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.130G>T; p.E44*; 3:119544838-119544838

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.72G>T; p.V24V; 3:119557657-119557657

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.130G>T; p.E44*; 3:119544838-119544838

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.396T>C; p.A132A; 3:119544572-119544572

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.82C>G; p.L28V; 3:119557647-119557647

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.82C>G; p.L28V; 3:119557647-119557647

 livercarcinomaSubstitution - Missense

c.544T>A; p.L182I; 3:119537293-119537293

 stomachadenocarcinomaSubstitution - Missense

c.624G>C; p.M208I; 3:119537213-119537213

 skinmalignant_melanomaSubstitution - Missense

c.629C>G; p.T210S; 3:119537208-119537208

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.647G>T; p.C216F; 3:119537190-119537190

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.681G>C; p.Q227H; 3:119537156-119537156

 skinmalignant_melanomaSubstitution - Missense

c.530A>G; p.E177G; 3:119537307-119537307

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.477G>A; p.R159R; 3:119537360-119537360

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.477G>A; p.R159R; 3:119537360-119537360

 skinmalignant_melanomaSubstitution - coding silent

c.856C>T; p.R286C; 3:119527782-119527782

 oesophagus; middle_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.856C>T; p.R286C; 3:119527782-119527782

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.23G>A; p.G8E; 3:119557706-119557706

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.57C>A; p.F19L; 3:119557672-119557672

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.240C>A; p.D80E; 3:119544728-119544728

 livercarcinomaSubstitution - Missense

c.210G>A; p.K70K; 3:119544758-119544758

 skinmalignant_melanomaSubstitution - coding silent

c.821G>A; p.R274K; 3:119527817-119527817

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.161T>C; p.V54A; 3:119544807-119544807

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.674T>A; p.V225E; 3:119537163-119537163

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.494C>T; p.S165F; 3:119537343-119537343

 breastcarcinomaSubstitution - Missense

c.832G>C; p.E278Q; 3:119527806-119527806

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.541G>T; p.E181*; 3:119537296-119537296

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.574G>T; p.D192Y; 3:119537263-119537263

 skinmalignant_melanomaSubstitution - Missense

c.378C>G; p.F126L; 3:119544590-119544590

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.419-10C>T; p.?; 3:119537428-119537428

 livercarcinomaUnknown

c.289A>C; p.N97H; 3:119544679-119544679

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.210G>T; p.K70N; 3:119544758-119544758

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.188G>A; p.R63H; 3:119544780-119544780

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.418+4G>T; p.?; 3:119544546-119544546

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasmUnknown

c.255C>T; p.P85P; 3:119544713-119544713

 breastcarcinomaSubstitution - coding silent

c.6C>T; p.G2G; 3:119557723-119557723

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.148T>C; p.C50R; 3:119544820-119544820

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.628A>G; p.T210A; 3:119537209-119537209

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.496G>A; p.G166R; 3:119537341-119537341

 skinmalignant_melanomaSubstitution - Missense

c.404C>T; p.T135M; 3:119544564-119544564

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.95G>C; p.C32S; 3:119557634-119557634

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.373G>A; p.A125T; 3:119544595-119544595

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.373G>A; p.A125T; 3:119544595-119544595

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.613G>T; p.D205Y; 3:119537224-119537224

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.405G>C; p.T135T; 3:119544563-119544563

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.352G>A; p.V118I; 3:119544616-119544616

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.765T>G; p.N255K; 3:119529873-119529873

 kidneyother; neoplasmSubstitution - Missense

c.256G>A; p.E86K; 3:119544712-119544712

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.445G>A; p.D149N; 3:119537392-119537392

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.836G>T; p.R279I; 3:119527802-119527802

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.120G>A; p.K40K; 3:119544848-119544848

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.320G>A; p.R107H; 3:119544648-119544648

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.120G>A; p.K40K; 3:119544848-119544848

 upper_aerodigestive_tract; mouthcarcinomaSubstitution - coding silent

c.320G>A; p.R107H; 3:119544648-119544648

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.747T>C; p.I249I; 3:119529891-119529891

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.43C>T; p.P15S; 3:119557686-119557686

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense