| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 941 |
Name | CD80 |
Synonym | B7|B7-1|B7.1|BB1|CD28LG|CD28LG1|LAB7;CD80 molecule;CD80;CD80 molecule |
Definition | B-lymphocyte activation antigen B7|CD80 antigen (CD28 antigen ligand 1, B7-1 antigen)|CTLA-4 counter-receptor B7.1|T-lymphocyte activation antigen CD80|activation B7-1 antigen|costimulatory factor CD80|costimulatory molecule variant IgV-CD80 |
Position | 3q13.3-q21 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | the co-stimulatory signal during t-cell activation;PID BioCarta;100193 |
Pathway | Signaling in Immune system;Reactome;REACT:6900 |
Pathway | Type I diabetes mellitus;KEGG PATHWAY;hsa04940 |
Pathway | Allograft rejection;KEGG PATHWAY;hsa05330 |
Pathway | Viral myocarditis;KEGG PATHWAY;hsa05416 |
Pathway | Toll-like receptor signaling pathway;KEGG PATHWAY;hsa04620 |
Pathway | Cell adhesion molecules (CAMs);KEGG PATHWAY;hsa04514 |
Pathway | Graft-versus-host disease;KEGG PATHWAY;hsa05332 |
Pathway | TCR signaling in naive CD8+ T cells;PID Curated;200062 |
Pathway | Systemic lupus erythematosus;KEGG PATHWAY;hsa05322 |
Pathway | TCR signaling in naive CD4+ T cells;PID Curated;200022 |
Pathway | Autoimmune thyroid disease;KEGG PATHWAY;hsa05320 |
Pathway | Intestinal immune network for IgA production;KEGG PATHWAY;hsa04672 |
Disease | Ulcerative colitis;FunDO |
Disease | Herpes;FunDO |
Disease | Adenovirus infection;FunDO |
Disease | Stomach cancer;FunDO |
Disease | Squamous cell cancer;FunDO |
Disease | Thyroiditis;FunDO |
Disease | IMMUNE;GAD |
Disease | IGA glomerulonephritis;FunDO |
Disease | Celiac disease;NHGRI |
Disease | Rheumatoid arthritis;FunDO |
Disease | Multiple sclerosis;FunDO |
Disease | Melanoma;FunDO |
Disease | Nasopharyngeal cancer;FunDO |
Disease | Sarcoidosis;FunDO |
Disease | Tuberculosis;FunDO |
Disease | Graves' disease;FunDO |
Disease | HIV infection;FunDO |
Disease | Liver cancer;FunDO |
Disease | Celiac Disease;GAD |
Disease | Atherosclerosis;FunDO |
External Links | |
Links to Entrez Gene | 941 |
Links to all GeneRIF Items | 941 |
Links to iHOP | 941 |
Sequence Information | |
Nucleotide Sequence | >941 : length: 3271 TGTTCTCTAGCTACATCCTGGTTTTACTGCTGCTGTGACTGAGTCAATGAAGCACCTACT GTGTGCCAGGTGGGCCATAAAAGTTGAGGCTAGGATTCCTGCACTCAAAGAGGTCTGCAT ATGTTAGTTGCGGAAATGCAAAGCTAACCCATGTAGAACAAGCAAAGAGCAATGAAATGC TTTGCCCTGATTGTAGGAGCCCAAGATCTGGGAAAGTGGGTAACAGACTGGGCTGCAGGA AGGAGGGCAGGCTTTACAGAGGCAGATGGATGATGGAGAGAGAATTCTGGTCAGGGCAAC AGCCTGGACAAAGGCACAAAGGTAAGGATGAGGCTGGCACAGGTGTTCATTCTTTTGTTT AATCATTTATTAATTCAACAAACATGAGCATCTCCTAAAACCAAGAGACTTTTCTTGGTC CTGGGGACATGGCTCTTGCATTTGTGAAATTTACTATCATTGGAAAGAGGAAAAGTAATC CAATAGCCACTCAAATGAATGTGTTAAAGTGTGGCCAACAAACAAAGCCACGTGCTTTGA AGGCAGGGCACAGGCACTGCCTGAGGAAGTGCTGTCTTCCTCTGCCAGCAAGAAGGGGCA GTGAGCTGGGAAGTAGCAGAGGAGGGACTGGCCCAGTGAGCAAGAACCGGACCCTGCAGC ACTTGTGTTATCCACGTGACCAAGGAAGTGAAAGAAGTGGCAACGCTGTCCTGTGGTCAC AATGTTTCTGTTGAAGAGCTGGCACAAACTCGCATCTACTGGCAAAAGGAGAAGAAAATG GTGCTGACTATGATGTCTGGGGACATGAATATATGGCCCGAGTACAAGAACCGGACCATC TTTGATATCACTAATAACCTCTCCATTGTGATCCTGGCTCTGCGCCCATCTGACGAGGGC ACATACGAGTGTGTTGTTCTGAAGTATGAAAAAGACGCTTTCAAGCGGGAACACCTGGCT GAAGTGACGTTATCAGTCAAAGCTGACTTCCCTACACCTAGTATATCTGACTTTGAAATT CCAACTTCTAATATTAGAAGGATAATTTGCTCAACCTCTGGAGGTTTTCCAGAGCCTCAC CTCTCCTGGTTGGAAAATGGAGAAGAATTAAATGCCATCAACACAACAGTTTCCCAAGAT CCTGAAACTGAGCTCTATGCTGTTAGCAGCAAACTGGATTTCAATATGACAACCAACCAC AGCTTCATGTGTCTCATCAAGTATGGACATTTAAGAGTGAATCAGACCTTCAACTGGAAT ACAACCAAGCAAGAGCATTTTCCTGATAACCTGCTCCCATCCTGGGCCATTACCTTAATC TCAGTAAATGGAATTTTTGTGATATGCTGCCTGACCTACTGCTTTGCCCCAAGATGCAGA GAGAGAAGGAGGAATGAGAGATTGAGAAGGGAAAGTGTACGCCCTGTATAACAGTGTCCG CAGAAGCAAGGGGCTGAAAAGATCTGAAGGTCCCACCTCCATTTGCAATTGACCTCTTCT GGGAACTTCCTCAGATGGACAAGATTACCCCACCTTGCCCTTTACGTATCTGCTCTTAGG TGCTTCTTCACTTCAGTTGCTTTGCAGGAAGTGTCTAGAGGAATATGGTGGGCACAGAAG TAGCTCTGGTGACCTTGATCAAGGTGTTTTGAAATGCAGAATTCTTGAGTTCTGGAAGGG ACTTTAGAGAATACCAGTGTTATTAATGACAAAGGCACTGAGGCCCAGGGAGGTGACCCG AATTATAAAGGCCAGCGCCAGAACCCAGATTTCCTAACTCTGGTGCTCTTTCCCTTTATC AGTTTGACTGTGGCCTGTTAACTGGTATATACATATATATGTCAGGCAAAGTGCTGCTGG AAGTAGAATTTGTCCAATAACAGGTCAACTTCAGAGACTATCTGATTTCCTAATGTCAGA GTAGAAGATTTTATGCTGCTGTTTACAAAAGCCCAATGTAATGCATAGGAAGTATGGCAT GAACATCTTTAGGAGACTAATGGAAATATTATTGGTGTTTACCCAGTATTCCATTTTTTT CATTGTGTTCTCTATTGCTGCTCTCTCACTCCCCCATGAGGTACAGCAGAAAGGAGAACT ATCCAAAACTAATTTCCTCTGACATGTAAGACGAATGATTTAGGTACGTCAAAGCAGTAG TCAAGGAGGAAAGGGATAGTCCAAAGACTTAACTGGTTCATATTGGACTGATAATCTCTT TAAATGGCTTTATGCTAGTTTGACCTCATTTGTAAAATATTTATGAGAAAGTTCTCATTT AAAATGAGATCGTTGTTTACAGTGTATGTACTAAGCAGTAAGCTATCTTCAAATGTCTAA GGTAGTAACTTTCCATAGGGCCTCCTTAGATCCCTAAGATGGCTTTTTCTCCTTGGTATT TCTGGGTCTTTCTGACATCAGCAGAGAACTGGAAAGACATAGCCAACTGCTGTTCATGTT ACTCATGACTCCTTTCTCTAAAACTGCCTTCCACAATTCACTAGACCAGAAGTGGACGCA ACTTAAGCTGGGATAATCACATTATCATCTGAAAATCTGGAGTTGAACAGCAAAAGAAGA CAACATTTCTCAAATGCACATCTCATGGCAGCTAAGCCACATGGCTGGGATTTAAAGCCT TTAGAGCCAGCCCATGGCTTTAGCTACCTCACTATGCTGCTTCACAAACCTTGCTCCTGT GTAAAACTATATTCTCAGTGTAGGGCAGAGAGGTCTAACACCAACATAAGGTACTAGCAG TGTTTCCCGTATTGACAGGAATACTTAACTCAATAATTCTTTTCTTTTCCATTTAGTAAC AGTTGTGATGACTATGTTTCTATTCTAAGTAATTCCTGTATTCTACAGCAGATACTTTGT CAGCAATACTAAGGGAAGAAACAAAGTTGAACCGTTTCTTTAATAATGCTGATCTACTTT TTGTTGAATTTGTATTTTATTTCAAGTGTCAAAGAAATCATCTTTGTTTATTTAGATGAA ACCAAACACTACACATTTACACTCACACTGCTTCCAGGACCCAAGGGTTTCACAGACCAT TTGCCTACCTGGTTCTTTCCTCTCCTCTTTCCAGTGATTTCTAGAATACCCTTTCAAAGG ACCACATGAATATACGAACTGTAAAATTCAACTTTAATCTTTTGCGAAATGTTTTATTTA CTGCTTAAAATCTAGGTGGGTGGATATATTCATGTATGCATATATTGATAGATTAATACA AACATAAGTATGTATTTAAATTTAAGGATAA |
Protein Sequence | >941 : length: 288 MGHTRRQGTSPSKCPYLNFFQLLVLAGLSHFCSGVIHVTKEVKEVATLSCGHNVSVEELA QTRIYWQKEKKMVLTMMSGDMNIWPEYKNRTIFDITNNLSIVILALRPSDEGTYECVVLK YEKDAFKREHLAEVTLSVKADFPTPSISDFEIPTSNIRRIICSTSGGFPEPHLSWLENGE ELNAINTTVSQDPETELYAVSSKLDFNMTTNHSFMCLIKYGHLRVNQTFNWNTTKQEHFP DNLLPSWAITLISVNGIFVICCLTYCFAPRCRERRRNERLRRESVRPV |