Entrez Gene

Basic Information
Gene ID	8976
Name	WASL
Synonymous	Wiskott-Aldrich syndrome-like;WASL;Wiskott-Aldrich syndrome-like
Definition	neural Wiskott-Aldrich syndrome protein
Position	7q31.3
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.189T>C; p.G63G; 7:123709152-123709152	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1238T>G; p.I413S; 7:123692456-123692456	skin	malignant_melanoma	Substitution - Missense
c.443G>T; p.R148I; 7:123704651-123704651	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1303G>A; p.D435N; 7:123692391-123692391	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.233_234insT; p.L78fs*5; 7:123709107-123709108	lung	carcinoma; adenocarcinoma	Insertion - Frameshift
c.388T>A; p.F130I; 7:123706325-123706325	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1123C>T; p.P375S; 7:123692571-123692571	skin	malignant_melanoma	Substitution - Missense
c.877C>T; p.P293S; 7:123692817-123692817	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.33G>T; p.P11P; 7:123748702-123748702	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.133G>A; p.V45M; 7:123709208-123709208	liver	carcinoma	Substitution - Missense
c.133G>A; p.V45M; 7:123709208-123709208	liver	carcinoma	Substitution - Missense
c.1158G>A; p.P386P; 7:123692536-123692536	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1158G>A; p.P386P; 7:123692536-123692536	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.371A>G; p.E124G; 7:123706342-123706342	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1456+1G>A; p.?; 7:123689041-123689041	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.588G>T; p.K196N; 7:123696620-123696620	breast	carcinoma	Substitution - Missense
c.392G>A; p.R131Q; 7:123706321-123706321	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.392G>A; p.R131Q; 7:123706321-123706321	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.335G>A; p.G112E; 7:123706744-123706744	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.631C>T; p.H211Y; 7:123695864-123695864	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.800C>T; p.A267V; 7:123694741-123694741	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1428delG; p.R478fs*>28; 7:123689070-123689070	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.584A>C; p.K195T; 7:123696624-123696624	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.965C>T; p.P322L; 7:123692729-123692729	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.131C>T; p.A44V; 7:123709210-123709210	pancreas	carcinoma; acinar_carcinoma	Substitution - Missense
c.856G>T; p.G286W; 7:123692838-123692838	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1119A>C; p.P373P; 7:123692575-123692575	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.639A>G; p.G213G; 7:123695856-123695856	breast	carcinoma	Substitution - coding silent
c.1368T>A; p.S456S; 7:123689130-123689130	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.404C>T; p.T135I; 7:123706309-123706309	upper_aerodigestive_tract; larynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.221G>T; p.R74I; 7:123709120-123709120	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1335C>T; p.I445I; 7:123692359-123692359	skin	malignant_melanoma	Substitution - coding silent
c.216A>G; p.P72P; 7:123709125-123709125	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.391C>T; p.R131*; 7:123706322-123706322	skin; scalp	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.391C>T; p.R131*; 7:123706322-123706322	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.391C>T; p.R131*; 7:123706322-123706322	skin	malignant_melanoma	Substitution - Nonsense
c.308C>T; p.P103L; 7:123706771-123706771	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1225C>A; p.L409I; 7:123692469-123692469	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.384A>C; p.K128N; 7:123706329-123706329	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.211A>G; p.N71D; 7:123709130-123709130	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.385A>G; p.K129E; 7:123706328-123706328	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.559G>T; p.E187*; 7:123696649-123696649	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.938C>G; p.P313R; 7:123692756-123692756	liver	carcinoma	Substitution - Missense
c.422G>A; p.R141Q; 7:123706291-123706291	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.422G>A; p.R141Q; 7:123706291-123706291	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.725C>T; p.S242L; 7:123694816-123694816	skin	malignant_melanoma	Substitution - Missense
c.894T>A; p.G298G; 7:123692800-123692800	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.113G>A; p.C38Y; 7:123748622-123748622	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.699G>T; p.K233N; 7:123694842-123694842	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.20A>C; p.Q7P; 7:123748715-123748715	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.434C>G; p.S145C; 7:123706279-123706279	urinary_tract; bladder	carcinoma	Substitution - Missense
c.434C>G; p.S145C; 7:123706279-123706279	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.428G>C; p.R143T; 7:123706285-123706285	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.477G>A; p.M159I; 7:123696731-123696731	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; plasma_cell_myeloma	Substitution - Missense
c.57C>T; p.S19S; 7:123748678-123748678	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.57C>T; p.S19S; 7:123748678-123748678	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.57C>T; p.S19S; 7:123748678-123748678	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1128G>A; p.P376P; 7:123692566-123692566	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.421C>T; p.R141*; 7:123706292-123706292	pancreas	carcinoma	Substitution - Nonsense
c.413delT; p.L138fs*27; 7:123706300-123706300	ovary	carcinoma; serous_carcinoma	Deletion - Frameshift
c.12C>T; p.V4V; 7:123748723-123748723	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.989C>A; p.P330Q; 7:123692705-123692705	breast	carcinoma	Substitution - Missense
c.1324C>T; p.R442*; 7:123692370-123692370	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.605A>G; p.D202G; 7:123696603-123696603	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1382C>T; p.P461L; 7:123689116-123689116	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.58C>T; p.L20L; 7:123748677-123748677	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.907_909delCCT; p.P303delP; 7:123692785-123692787	skin	malignant_melanoma	Deletion - In frame
c.907_909delCCT; p.P303delP; 7:123692785-123692787	skin	malignant_melanoma	Deletion - In frame
c.1457-1G>C; p.?; 7:123684581-123684581	breast	carcinoma	Unknown
c.629+1G>A; p.?; 7:123696578-123696578	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.1298G>C; p.G433A; 7:123692396-123692396	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1379C>A; p.T460K; 7:123689119-123689119	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.811G>A; p.E271K; 7:123694730-123694730	skin	malignant_melanoma	Substitution - Missense
c.1168G>T; p.G390C; 7:123692526-123692526	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1263_1264insA; p.V422fs*31; 7:123692430-123692431	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.806A>C; p.K269T; 7:123694735-123694735	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.301A>C; p.N101H; 7:123706778-123706778	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.717T>C; p.C239C; 7:123694824-123694824	skin	malignant_melanoma	Substitution - coding silent
c.294T>G; p.F98L; 7:123706785-123706785	skin	malignant_melanoma	Substitution - Missense
c.1130C>T; p.P377L; 7:123692564-123692564	liver	carcinoma	Substitution - Missense
c.1073C>A; p.P358H; 7:123692621-123692621	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.446G>A; p.R149Q; 7:123704648-123704648	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.615A>G; p.T205T; 7:123696593-123696593	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.925G>A; p.A309T; 7:123692769-123692769	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1514A>G; p.D505G; 7:123684523-123684523	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1124C>A; p.P375Q; 7:123692570-123692570	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1171C>A; p.L391M; 7:123692523-123692523	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.34_35insCGC; p.P11_R12insP; 7:123748700-123748701	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Insertion - In frame
c.670G>C; p.D224H; 7:123695825-123695825	breast	carcinoma	Substitution - Missense
c.699G>A; p.K233K; 7:123694842-123694842	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1263_1268delAGTGGA; p.V422_E423delVE; 7:123692426-123692431	liver	carcinoma	Deletion - In frame
c.784A>G; p.T262A; 7:123694757-123694757	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.821G>T; p.R274M; 7:123694720-123694720	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1511A>G; p.E504G; 7:123684526-123684526	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.814C>T; p.L272L; 7:123694727-123694727	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.648T>C; p.G216G; 7:123695847-123695847	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.148G>A; p.A50T; 7:123709193-123709193	liver	carcinoma	Substitution - Missense
c.337G>T; p.D113Y; 7:123706742-123706742	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.961G>T; p.A321S; 7:123692733-123692733	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.609A>G; p.I203M; 7:123696599-123696599	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.622A>C; p.N208H; 7:123696586-123696586	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.716G>A; p.C239Y; 7:123694825-123694825	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1474G>A; p.D492N; 7:123684563-123684563	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.540C>T; p.N180N; 7:123696668-123696668	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.901C>G; p.P301A; 7:123692793-123692793	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1398A>G; p.G466G; 7:123689100-123689100	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.1503T>C; p.D501D; 7:123684534-123684534	liver	carcinoma	Substitution - coding silent
c.1503T>C; p.D501D; 7:123684534-123684534	liver	carcinoma	Substitution - coding silent
c.1263delA; p.V422fs*17; 7:123692431-123692431	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1263delA; p.V422fs*17; 7:123692431-123692431	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1263delA; p.V422fs*17; 7:123692431-123692431	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1263delA; p.V422fs*17; 7:123692431-123692431	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1263delA; p.V422fs*17; 7:123692431-123692431	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.709G>A; p.D237N; 7:123694832-123694832	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.709G>A; p.D237N; 7:123694832-123694832	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.709G>A; p.D237N; 7:123694832-123694832	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.420T>C; p.R140R; 7:123706293-123706293	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.907C>G; p.P303A; 7:123692787-123692787	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense

COSMIC somatic mutation [Top]