| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 8976 |
Name | WASL |
Synonym | N-WASP|NWASP|WASPB;Wiskott-Aldrich syndrome-like;WASL;Wiskott-Aldrich syndrome-like |
Definition | neural Wiskott-Aldrich syndrome protein |
Position | 7q31.3 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Interactions of the immunoglobulin superfamily (IgSF) member proteins;Reactome;REACT:23853 |
Pathway | Fc gamma R-mediated phagocytosis;KEGG PATHWAY;hsa04666 |
Pathway | Nephrin/Neph1 signaling in the kidney podocyte;PID Curated;200132 |
Pathway | how does salmonella hijack a cell;PID BioCarta;100037 |
Pathway | role of pi3k subunit p85 in regulation of actin organization and cell migration;PID BioCarta;100211 |
Pathway | Regulation of actin cytoskeleton;KEGG PATHWAY;hsa04810 |
Pathway | ErbB1 downstream signaling;PID Curated;200113 |
Pathway | NOSTRIN mediated eNOS trafficking;PID Reactome;500851 |
Pathway | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met);PID Curated;200032 |
Pathway | Metabolism of nitric oxide;Reactome;REACT:12508 |
Pathway | Bacterial invasion of epithelial cells;KEGG PATHWAY;hsa05100 |
Pathway | Adherens junction;KEGG PATHWAY;hsa04520 |
Pathway | EPHB forward signaling;PID Curated;200041 |
Pathway | DCC mediated attractive signaling;PID Reactome;500089 |
Pathway | EGF receptor (ErbB1) signaling pathway;PID Curated;200085 |
Pathway | Shigellosis;KEGG PATHWAY;hsa05131 |
Pathway | Axon guidance;Reactome;REACT:18266 |
Pathway | Signaling events mediated by focal adhesion kinase;PID Curated;200192 |
Pathway | CDC42 signaling events;PID Curated;200057 |
Pathway | Pathogenic Escherichia coli infection;KEGG PATHWAY;hsa05130 |
Pathway | Huntington disease;PANTHER;P00029 |
Pathway | Chemokine signaling pathway;KEGG PATHWAY;hsa04062 |
Pathway | y branching of actin filaments;PID BioCarta;100254 |
Pathway | Cytoskeletal regulation by Rho GTPase;PANTHER;P00016 |
Pathway | Netrin-mediated signaling;PID Curated;200074 |
Disease | Breast cancer;FunDO |
Disease | Intestinal disease;FunDO |
External Links | |
Links to Entrez Gene | 8976 |
Links to all GeneRIF Items | 8976 |
Links to iHOP | 8976 |
Sequence Information | |
Nucleotide Sequence | >8976 : length: 4447 TGCCATGTTGGATTGTGCGGCCGCCGCCGCCGCTGCGGGAGGGTTGGGGGAGGAGTTGGG AGTTTAGCGCAGTCGCCGGAGTGCGAGGACAACGACCATCCGGCCCTAGCCTGGCCGGGC GGGTGCCGGGAGCTTCCCTTTCTCAGCGCGGCGCGAAGGTGGCTCGCCGTCAGCGCCTGC TTCCCTCGACCTCGTCCTCCTCCCCGCTCCGGAGGAGCTGCGAGATGTGGCGCCTCTGAC TCCACTTCTCCCCGCCCCTGTCACCGAGAGGGGGAACGAGCTCTCGCCCACTCGCCGGAG GAGACGGCCCTGGACTCCCAACCCCGCCGGCGAAACCATGAGCTCCGTCCAGCAGCAGCC GCCGCCGCCGCGGAGGGTCACCAACGTGGGGTCCCTGTTGCTCACCCCGCAGGAGAACGA GTCCCTCTTCACTTTCCTCGGCAAGAAATGTGTGACTATGTCTTCAGCAGTGGTGCAGTT ATATGCAGCAGATCGGAACTGTATGTGGTCAAAGAAGTGCAGTGGTGTTGCTTGTCTTGT TAAGGACAATCCACAGAGATCTTATTTTTTAAGAATATTTGACATTAAGGATGGGAAACT ATTGTGGGAACAAGAGCTATACAATAACTTTGTATATAATAGTCCTAGAGGATATTTTCA TACCTTTGCTGGAGATACTTGTCAAGTTGCTCTTAATTTTGCCAATGAAGAAGAAGCAAA AAAATTTCGAAAAGCAGTTACAGACCTTTTGGGCCGTCGACAAAGGAAATCTGAGAAAAG ACGAGATCCCCCAAATGGTCCTAATCTACCCATGGCTACAGTTGATATAAAAAATCCAGA AATCACAACAAATAGATTTTATGGTCCACAAGTCAACAACATCTCCCATACCAAAGAAAA GAAGAAGGGAAAAGCTAAAAAGAAGAGATTAACCAAGGCAGATATAGGAACACCAAGCAA TTTCCAGCACATTGGACATGTTGGTTGGGATCCAAATACAGGCTTTGATCTGAATAATTT GGATCCAGAATTGAAGAATCTTTTCGATATGTGTGGAATCTCAGAGGCACAACTTAAAGA CAGAGAAACATCAAAAGTTATATATGACTTTATTGAAAAAACAGGAGGTGTTGAAGCTGT TAAAAATGAACTGCGGAGGCAAGCACCACCACCTCCACCACCATCAAGGGGAGGGCCACC TCCTCCTCCTCCCCCTCCACACAACTCAGGTCCTCCTCCTCCTCCTGCTAGGGGAAGAGG CGCTCCTCCCCCACCACCTTCAAGAGCTCCCACAGCTGCACCTCCACCACCGCCTCCTTC CAGGCCAAGTGTAGCAGTCCCTCCACCACCGCCAAATAGGATGTACCCTCCTCCACCTCC AGCCCTTCCCTCCTCAGCACCTTCAGGGCCTCCACCACCACCTCCATCTGTGTTGGGGGT AGGGCCAGTGGCACCACCCCCACCGCCTCCACCTCCACCTCCTCCTGGGCCACCGCCCCC GCCTGGCCTGCCTTCTGATGGGGACCATCAGGTTCCAACTACTGCAGGAAACAAAGCAGC TCTTTTAGATCAAATTAGAGAGGGTGCTCAGCTAAAAAAAGTGGAGCAGAACAGTCGGCC AGTGTCCTGCTCTGGACGAGATGCACTGTTAGACCAGATACGACAGGGTATCCAACTAAA ATCTGTGGCTGATGGCCAAGAGTCTACACCACCAACACCTGCACCCACTTCAGGAATTGT GGGTGCATTAATGGAAGTGATGCAGAAAAGGAGCAAAGCCATTCATTCTTCAGATGAAGA TGAAGATGAAGATGATGAAGAAGATTTTGAGGATGATGATGAGTGGGAAGACTGATCTAT ATATTATATATATATATATATTTTTAAGGTGAAATACTAAACACTACTTTCTGTCTGTGG ATTCTGTAAAATTATCATGTAAATGTTCTACCAATTTGCTGTATATTTTTGTTGCCTTTT TTGCTTTTTTTTAATCTGTGCAATACCTCATTTAATCTGTAAAGGTTTGTCGTAATCCTC TACAAAGCTACTCCCTGTTATTGTGTGCAAGTTTACACCAGGATGCTCACTTGATTTGTG AATATTTTTCATTCCATCAACAAGGGAGTTTAAATACTATATGTGAGACTGACAAAAACC TTAATGTAATTTACTTATAATGCCAGAAGGAAAACACTATTTTCATACCCTACTTTTTCT GTACCTAAATTTTCTTAAAAAAAAATCTAGTATAGCACTACATTCTTTTTTAAGTGATGC AGACCTTAGTTTCTTTAGCCCCTTTATTTTGAATACAATGCTACATATGAATGTTGAAGC TGATACATTGCACAGTTCTGTAGACATCACTACACCGATGTAGTTTCTCAAATTTTAGCA ATATGCTCTACATAAAATCACTACAGAGATACTAGTGGGGAAGACGATTAACACACCTCT TACAGTAATACTGCCTGTTATTGGTATAGCAGTGGTATTTGCAGACTGGGATCATAAGGA GCCCTTAAATACTTGTTATTGACTGGGGTTATTTTTATGCTGTAGCAAATGTGACAGGCT CTTTTTAGCAAAATTTTTGAAAATTTTTTTGGTATTACTCTGAAACAAAATTTAAGTTGG AGTTTCAGGGATTTAGGGAGTAGTTTTCATTCTACATGAACTGAGGTAATATTATGGTAA CTCCAATATTTGGTTAAAAAAACTATACAAATCAGAATAGTACTAAAATACTGTAGAATT TTAGCATTTTTATTTTGCACTTTGTGTGGATTGAGGTGTTCAGAAATACCAACCATAAAA ATGTAATCTAGTTGGCAAAGGTGTGCGCTAAAACACGGAACCGAACATGCATTGATTTGG ATAACTTTTGAGGGTTTTTGTCAAATAGCATGTGAAGAGTTACATTTTTCTTAAAAGATT GGTGGTCCCAATGTCAGAGTTCTTGGAACAGATAACTGAATGATAGATTTTTTTTTTTTA AAGATAAAACTTTACAACCTGCACATTTGTTATGCATACTAAATGGTGTGTTAAAATTAG GGTTTCTTTGCCTCTCTACACTACACTAATCTGCCTAAAGGTGGTTGTTTCATATTTATA ATGCTAATTATCATACCTACCTACTTTAAATTTTAGGTAGAAAATTATCTGATTTAAATA CAAACATATTTTTCTCACATTGAGTAATATGCATAATGTAGTTCCAAATGTATTTCATTA CTATAGTCACAATATCCAACTAAAAATTACGCTATCTAGAATTGTACCAACCAAAATCTC GTATTGGCAGATCTTGACAGGCTGGACCTGCAAGATGTGGCTTGAATTTTAACCATTTAT TACATAATCTCTAGTGATCATGCATCTAGTTATCATAAGAAATAATTTAAAAGGTTTTGT TGCTGAAAGCAGTAAGTGGTGCAGTAAAATACTTAAGTTATTCAAAGAATGTTATCTTTC TTGCAAGAGTAATTTAAGCACATGGGAAAGATTCTAGACTTTTTGTTTCTTGCAACAACA GTGCCCTCTGCTGCTAGAAACCTTTTTCTACTTACTATCATTTTTATTGTGGCTTGAGCT CAGTCAATCTGGTGCAGATGAGGCTGGACAACTACTAACCAATAAAATCAGGAGTTTGTA CAAAAGTTAAATGGAACATTATAATTATTTTAAGTAATGTTAATTGAAAAAATTTTTTCT TTTTGACAATATAAAAAACATTTTAAATTTCCTAGAAATGTCTTCAGGGTAATGCCAATT TAAGATCTCTCTTAACTTGTGGCCAAGAAATTCTAGATTTTCCAGCTGACTTTGGTATAA TATATATTTATCAGGAACTTCTCTCAGCAGAGAGTACCCATTCTTCGAGTTCAAAGCACA ATTTTAAACATGTAAAATGGATATATAATTTGCCAAAGGTAATTAATTTATTCTTTTTTT CTTAAAGAAGAAAAAGACATTGGTTGTTGTTACAAAAAGTCTAAATTACTGTTGGTTGAA ACACAGCAGCTGTGGAGTTCAGTCCAGGCATGAAGACTAAATCTGCTTTACCAAGTAAGG TGTAAGGTTGCATGTTTCAGTCCTCTACCATCCTGCACTGTGAGCAGCACTATACCTGTG CGTTGTCTGAAAGCCTTCCGTATATTCTCCAGCTAAATGGTCGTCTGGTAGCCTTTGCAT TTAACAAACTAGCATGAGGCTTTTTATATCTAAATGCTACGTGATAGACAATTTCAGCTA GCCACATATTGTATGTATGAGATTCATAAAGACTTTCAATCATTTCATTTTCAGACAACT GAAATTTTGTTTAGTATGTGAATTCTTTTTTTGAAATGTATAGTGAATAGGATGTTGCAC TGGTGGCAATTCATCATGGAGCATAATAAAATTAATTTGACCCAAATAGAATAAAATAAT GTGTTTC |
Protein Sequence | >8976 : length: 505 MSSVQQQPPPPRRVTNVGSLLLTPQENESLFTFLGKKCVTMSSAVVQLYAADRNCMWSKK CSGVACLVKDNPQRSYFLRIFDIKDGKLLWEQELYNNFVYNSPRGYFHTFAGDTCQVALN FANEEEAKKFRKAVTDLLGRRQRKSEKRRDPPNGPNLPMATVDIKNPEITTNRFYGPQVN NISHTKEKKKGKAKKKRLTKADIGTPSNFQHIGHVGWDPNTGFDLNNLDPELKNLFDMCG ISEAQLKDRETSKVIYDFIEKTGGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPP PPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPP PPPSVLGVGPVAPPPPPPPPPPPGPPPPPGLPSDGDHQVPTTAGNKAALLDQIREGAQLK KVEQNSRPVSCSGRDALLDQIRQGIQLKSVADGQESTPPTPAPTSGIVGALMEVMQKRSK AIHSSDEDEDEDDEEDFEDDDEWED |