Entrez Gene

Basic Information
Gene ID	83854
Name	ANGPTL6
Synonymous	angiopoietin-like 6;ANGPTL6;angiopoietin-like 6
Definition	angiopoietin-like protein 6\|angiopoietin-related growth factor\|angiopoietin-related protein 5\|angiopoietin-related protein 6
Position	19p13.2
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.839G>A; p.R280H; 19:10093805-10093805	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.839G>A; p.R280H; 19:10093805-10093805	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.839G>A; p.R280H; 19:10093805-10093805	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.659T>G; p.L220R; 19:10094862-10094862	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.830G>A; p.R277Q; 19:10093814-10093814	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1303G>A; p.G435S; 19:10092699-10092699	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.478C>G; p.L160V; 19:10096086-10096086	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.845T>C; p.V282A; 19:10093799-10093799	liver	carcinoma	Substitution - Missense
c.845T>C; p.V282A; 19:10093799-10093799	liver	carcinoma	Substitution - Missense
c.1137G>A; p.Q379Q; 19:10093434-10093434	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1288_1289GG>AA; p.G430N; 19:10092713-10092714	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1061delG; p.G354fs*115; 19:10093510-10093510	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1061delG; p.G354fs*115; 19:10093510-10093510	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1000G>A; p.V334M; 19:10093571-10093571	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.910G>C; p.D304H; 19:10093734-10093734	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.854T>C; p.V285A; 19:10093790-10093790	liver	carcinoma	Substitution - Missense
c.854T>C; p.V285A; 19:10093790-10093790	liver	carcinoma	Substitution - Missense
c.738C>T; p.H246H; 19:10094783-10094783	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1333G>A; p.G445S; 19:10092669-10092669	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.675G>T; p.E225D; 19:10094846-10094846	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.589C>T; p.P197S; 19:10094932-10094932	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.844G>A; p.V282I; 19:10093800-10093800	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.751A>C; p.T251P; 19:10094770-10094770	breast	carcinoma	Substitution - Missense
c.212G>T; p.R71L; 19:10096352-10096352	ovary	other; neoplasm	Substitution - Missense
c.1154G>C; p.G385A; 19:10093417-10093417	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1111G>A; p.D371N; 19:10093460-10093460	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.715G>T; p.A239S; 19:10094806-10094806	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1191C>T; p.S397S; 19:10093380-10093380	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1127G>T; p.R376L; 19:10093444-10093444	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.905G>T; p.R302M; 19:10093739-10093739	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.451C>T; p.Q151*; 19:10096113-10096113	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.972C>T; p.D324D; 19:10093599-10093599	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1116C>A; p.H372Q; 19:10093455-10093455	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1023G>A; p.G341G; 19:10093548-10093548	skin	malignant_melanoma	Substitution - coding silent
c.425G>A; p.R142H; 19:10096139-10096139	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.1061_1062insG; p.R355fs*8; 19:10093509-10093510	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.1061_1062insG; p.R355fs*8; 19:10093509-10093510	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.1384G>A; p.A462T; 19:10092618-10092618	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1184C>T; p.P395L; 19:10093387-10093387	skin	malignant_melanoma	Substitution - Missense
c.1095C>T; p.S365S; 19:10093476-10093476	lung	carcinoma; small_cell_carcinoma	Substitution - coding silent
c.947A>G; p.Y316C; 19:10093697-10093697	urinary_tract; bladder	carcinoma	Substitution - Missense
c.947A>G; p.Y316C; 19:10093697-10093697	pancreas	other; cystic_tumour	Substitution - Missense
c.1304G>A; p.G435D; 19:10092698-10092698	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1031A>C; p.E344A; 19:10093540-10093540	liver	carcinoma	Substitution - Missense
c.1302C>T; p.H434H; 19:10092700-10092700	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.617C>A; p.P206Q; 19:10094904-10094904	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.956G>A; p.G319D; 19:10093615-10093615	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.515C>T; p.T172I; 19:10096049-10096049	liver	carcinoma	Substitution - Missense
c.515C>T; p.T172I; 19:10096049-10096049	liver	carcinoma	Substitution - Missense
c.1288G>A; p.G430S; 19:10092714-10092714	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1288G>A; p.G430S; 19:10092714-10092714	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.618G>A; p.P206P; 19:10094903-10094903	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.628G>A; p.V210M; 19:10094893-10094893	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.901C>G; p.R301G; 19:10093743-10093743	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.492C>T; p.F164F; 19:10096072-10096072	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1374C>G; p.L458L; 19:10092628-10092628	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.899A>T; p.Q300L; 19:10093745-10093745	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1222+3A>G; p.?; 19:10093346-10093346	skin; head_neck	carcinoma; squamous_cell_carcinoma	Unknown

COSMIC somatic mutation [Top]