Entrez Gene

Basic Information
Gene ID	80150
Name	ASRGL1
Synonymous	asparaginase like 1;ASRGL1;asparaginase like 1
Definition	L-asparaginase\|L-asparagine amidohydrolase\|asparaginase-like 1 protein\|asparaginase-like protein 1\|beta-aspartyl-peptidase\|isoaspartyl dipeptidase\|isoaspartyl peptidase/L-asparaginase
Position	11q12.3
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.495C>T; p.N165N; 11:62389136-62389136	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.495C>T; p.N165N; 11:62389136-62389136	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.213A>G; p.T71T; 11:62356347-62356347	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.892G>C; p.D298H; 11:62392249-62392249	urinary_tract; bladder	carcinoma	Substitution - Missense
c.730G>T; p.V244L; 11:62392087-62392087	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.263C>G; p.S88C; 11:62356397-62356397	urinary_tract; bladder	carcinoma	Substitution - Missense
c.263C>G; p.S88C; 11:62356397-62356397	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.263C>G; p.S88C; 11:62356397-62356397	urinary_tract; bladder	carcinoma	Substitution - Missense
c.19G>T; p.V7F; 11:62337996-62337996	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.440G>A; p.R147H; 11:62357093-62357093	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.429delA; p.N144fs*37; 11:62357082-62357082	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.923C>T; p.P308L; 11:62392280-62392280	skin	malignant_melanoma	Substitution - Missense
c.900C>T; p.D300D; 11:62392257-62392257	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.403C>G; p.P135A; 11:62357056-62357056	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.650C>T; p.S217L; 11:62391561-62391561	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.151G>T; p.A51S; 11:62338128-62338128	liver	carcinoma	Substitution - Missense
c.151G>T; p.A51S; 11:62338128-62338128	liver	carcinoma	Substitution - Missense
c.78C>T; p.G26G; 11:62338055-62338055	pancreas	carcinoma	Substitution - coding silent
c.579G>A; p.M193I; 11:62389220-62389220	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.8C>T; p.P3L; 11:62337985-62337985	oesophagus; upper_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.599C>T; p.S200L; 11:62389240-62389240	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.474G>T; p.Q158H; 11:62357127-62357127	oesophagus	carcinoma	Substitution - Missense
c.753G>A; p.S251S; 11:62392110-62392110	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.156C>A; p.V52V; 11:62338133-62338133	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.507G>A; p.V169V; 11:62389148-62389148	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.582C>T; p.V194V; 11:62389223-62389223	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.368C>A; p.A123E; 11:62357021-62357021	pleura	pulmonary_blastoma	Substitution - Missense
c.369G>A; p.A123A; 11:62357022-62357022	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.193T>C; p.C65R; 11:62356327-62356327	liver	carcinoma	Substitution - Missense
c.147G>T; p.E49D; 11:62338124-62338124	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.911T>C; p.I304T; 11:62392268-62392268	skin	malignant_melanoma	Substitution - Missense
c.728C>T; p.T243M; 11:62392085-62392085	prostate	carcinoma	Substitution - Missense
c.894T>A; p.D298E; 11:62392251-62392251	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.561C>T; p.G187G; 11:62389202-62389202	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.580G>A; p.V194I; 11:62389221-62389221	skin	malignant_melanoma	Substitution - Missense
c.351G>C; p.L117L; 11:62357004-62357004	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.486T>C; p.C162C; 11:62357139-62357139	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.183C>T; p.F61F; 11:62338160-62338160	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.183C>T; p.F61F; 11:62338160-62338160	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.627C>T; p.A209A; 11:62391538-62391538	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.302_303CC>TT; p.P101L; 11:62356436-62356437	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.196G>A; p.G66R; 11:62356330-62356330	skin	malignant_melanoma	Substitution - Missense
c.589G>A; p.V197I; 11:62389230-62389230	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.584G>A; p.G195D; 11:62389225-62389225	skin; face	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.646G>A; p.V216I; 11:62391557-62391557	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.231G>A; p.M77I; 11:62356365-62356365	skin	malignant_melanoma	Substitution - Missense
c.752C>T; p.S251L; 11:62392109-62392109	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.752C>T; p.S251L; 11:62392109-62392109	skin	malignant_melanoma	Substitution - Missense
c.191-2A>T; p.?; 11:62356323-62356323	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Unknown
c.230T>C; p.M77T; 11:62356364-62356364	thyroid	carcinoma	Substitution - Missense
c.191-2A>T; p.?; 11:62356323-62356323	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Unknown
c.191-2A>T; p.?; 11:62356323-62356323	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Unknown
c.349C>T; p.L117L; 11:62357002-62357002	skin	malignant_melanoma	Substitution - coding silent
c.864C>T; p.A288A; 11:62392221-62392221	skin	malignant_melanoma	Substitution - coding silent
c.648C>T; p.V216V; 11:62391559-62391559	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.547G>A; p.A183T; 11:62389188-62389188	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense

COSMIC somatic mutation [Top]