Entrez Gene

Basic Information
Gene ID	7299
Name	TYR
Synonymous	tyrosinase;TYR;tyrosinase
Definition	LB24-AB\|SK29-AB\|monophenol monooxygenase\|oculocutaneous albinism IA\|tumor rejection antigen AB
Position	11q14.3
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.1492T>C; p.L498L; 11:89295268-89295268	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.272G>T; p.C91F; 11:89178225-89178225	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1484T>A; p.L495H; 11:89295260-89295260	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1533G>C; p.K511N; 11:89295309-89295309	pancreas	carcinoma; adenocarcinoma	Substitution - Missense
c.1366G>C; p.D456H; 11:89284954-89284954	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.283T>C; p.F95L; 11:89178236-89178236	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1162C>A; p.L388I; 11:89227948-89227948	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.468T>A; p.Y156*; 11:89178421-89178421	liver	carcinoma	Substitution - Nonsense
c.1509G>A; p.K503K; 11:89295285-89295285	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.929C>T; p.P310L; 11:89191311-89191311	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1468G>C; p.A490P; 11:89295244-89295244	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.931A>T; p.R311W; 11:89191313-89191313	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.465C>A; p.T155T; 11:89178418-89178418	thyroid	carcinoma	Substitution - coding silent
c.1410A>C; p.Q470H; 11:89295186-89295186	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.958T>G; p.F320V; 11:89191340-89191340	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.950A>C; p.D317A; 11:89191332-89191332	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.776A>T; p.N259I; 11:89178729-89178729	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1058G>T; p.G353V; 11:89227844-89227844	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.237G>A; p.S79S; 11:89178190-89178190	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.237G>A; p.S79S; 11:89178190-89178190	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.237G>A; p.S79S; 11:89178190-89178190	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.237G>A; p.S79S; 11:89178190-89178190	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.237G>A; p.S79S; 11:89178190-89178190	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.237G>A; p.S79S; 11:89178190-89178190	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.711C>A; p.D237E; 11:89178664-89178664	breast	carcinoma	Substitution - Missense
c.980A>G; p.Y327C; 11:89191362-89191362	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.81T>A; p.S27S; 11:89178034-89178034	breast	carcinoma	Substitution - coding silent
c.270G>A; p.Q90Q; 11:89178223-89178223	cervix	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1479A>G; p.A493A; 11:89295255-89295255	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.1049C>T; p.P350L; 11:89227835-89227835	skin	malignant_melanoma	Substitution - Missense
c.68C>T; p.A23V; 11:89178021-89178021	thyroid	carcinoma; medullary_carcinoma	Substitution - Missense
c.126C>T; p.D42D; 11:89178079-89178079	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.973A>G; p.T325A; 11:89191355-89191355	liver	carcinoma	Substitution - Missense
c.973A>G; p.T325A; 11:89191355-89191355	liver	carcinoma	Substitution - Missense
c.42G>A; p.Q14Q; 11:89177995-89177995	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.713G>A; p.W238*; 11:89178666-89178666	skin	malignant_melanoma	Substitution - Nonsense
c.1337G>C; p.G446A; 11:89284925-89284925	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.718G>T; p.D240Y; 11:89178671-89178671	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.782A>C; p.N261T; 11:89178735-89178735	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.6_7CC>AA; p.L3M; 11:89177959-89177960	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1204C>T; p.R402*; 11:89284792-89284792	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1204C>T; p.R402*; 11:89284792-89284792	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.723A>C; p.A241A; 11:89178676-89178676	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.113C>T; p.P38L; 11:89178066-89178066	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.113C>T; p.P38L; 11:89178066-89178066	central_nervous_system; brain	glioma	Substitution - Missense
c.152G>A; p.G51D; 11:89178105-89178105	breast	carcinoma	Substitution - Missense
c.113C>T; p.P38L; 11:89178066-89178066	urinary_tract; bladder	carcinoma	Substitution - Missense
c.467A>G; p.Y156C; 11:89178420-89178420	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.789C>A; p.L263L; 11:89178742-89178742	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1459G>T; p.V487F; 11:89295235-89295235	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.230G>A; p.R77Q; 11:89178183-89178183	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1511G>T; p.R504I; 11:89295287-89295287	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.61C>A; p.P21T; 11:89178014-89178014	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.390G>T; p.E130D; 11:89178343-89178343	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.760G>A; p.G254S; 11:89178713-89178713	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.760G>A; p.G254S; 11:89178713-89178713	stomach	adenocarcinoma	Substitution - Missense
c.1360G>A; p.D454N; 11:89284948-89284948	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1469C>T; p.A490V; 11:89295245-89295245	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.878C>T; p.P293L; 11:89191260-89191260	urinary_tract; bladder	carcinoma	Substitution - Missense
c.263C>T; p.T88I; 11:89178216-89178216	urinary_tract; bladder	carcinoma	Substitution - Missense
c.94G>A; p.E32K; 11:89178047-89178047	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.520G>A; p.D174N; 11:89178473-89178473	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1319T>G; p.I440S; 11:89284907-89284907	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.962G>A; p.C321Y; 11:89191344-89191344	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1265G>T; p.R422L; 11:89284853-89284853	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.799T>A; p.S267T; 11:89178752-89178752	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1404G>A; p.L468L; 11:89295180-89295180	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1562A>T; p.Y521F; 11:89295338-89295338	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.1333C>A; p.L445M; 11:89284921-89284921	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.114G>A; p.P38P; 11:89178067-89178067	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.933G>T; p.R311S; 11:89191315-89191315	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.732_733delTG; p.C244fs*1; 11:89178685-89178686	central_nervous_system; brain	glioma	Deletion - Frameshift
c.99G>C; p.K33N; 11:89178052-89178052	pancreas	carcinoma	Substitution - Missense
c.99G>C; p.K33N; 11:89178052-89178052	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.28C>A; p.L10M; 11:89177981-89177981	oesophagus	carcinoma	Substitution - Missense
c.1522C>T; p.P508S; 11:89295298-89295298	skin	malignant_melanoma	Substitution - Missense
c.649C>T; p.R217W; 11:89178602-89178602	pancreas	carcinoma	Substitution - Missense
c.972G>T; p.L324F; 11:89191354-89191354	liver	carcinoma	Substitution - Missense
c.972G>T; p.L324F; 11:89191354-89191354	liver	carcinoma	Substitution - Missense
c.373G>T; p.D125Y; 11:89178326-89178326	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1158C>G; p.F386L; 11:89227944-89227944	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.859T>G; p.S287A; 11:89191241-89191241	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1466C>A; p.T489N; 11:89295242-89295242	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.667C>A; p.Q223K; 11:89178620-89178620	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.825C>T; p.V275V; 11:89191207-89191207	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.997G>T; p.D333Y; 11:89191379-89191379	ovary	other; neoplasm	Substitution - Missense
c.505G>A; p.D169N; 11:89178458-89178458	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.505G>A; p.D169N; 11:89178458-89178458	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.1442C>T; p.A481V; 11:89295218-89295218	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.701C>T; p.P234L; 11:89178654-89178654	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.254A>G; p.Y85C; 11:89178207-89178207	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.589G>T; p.D197Y; 11:89178542-89178542	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.589G>T; p.D197Y; 11:89178542-89178542	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1068T>A; p.D356E; 11:89227854-89227854	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1030C>G; p.L344V; 11:89191412-89191412	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1068T>A; p.D356E; 11:89227854-89227854	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1470C>A; p.A490A; 11:89295246-89295246	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1272C>A; p.S424S; 11:89284860-89284860	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.187G>A; p.A63T; 11:89178140-89178140	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.546T>C; p.Y182Y; 11:89178499-89178499	breast	carcinoma	Substitution - coding silent
c.770C>A; p.P257H; 11:89178723-89178723	lung; left_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.208C>T; p.P70S; 11:89178161-89178161	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.208C>T; p.P70S; 11:89178161-89178161	skin	malignant_melanoma	Substitution - Missense
c.1528G>A; p.E510K; 11:89295304-89295304	skin; face	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.232G>T; p.E78*; 11:89178185-89178185	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.971T>C; p.L324S; 11:89191353-89191353	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.208C>T; p.P70S; 11:89178161-89178161	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Missense
c.1503T>C; p.R501R; 11:89295279-89295279	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.684T>C; p.D228D; 11:89178637-89178637	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.879C>T; p.P293P; 11:89191261-89191261	liver	carcinoma	Substitution - coding silent
c.832C>T; p.R278*; 11:89191214-89191214	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.218G>T; p.G73V; 11:89178171-89178171	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.117G>T; p.W39C; 11:89178070-89178070	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.401T>G; p.F134C; 11:89178354-89178354	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1213C>A; p.R405S; 11:89284801-89284801	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.239G>T; p.W80L; 11:89178192-89178192	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1042delG; p.A348fs*7; 11:89227828-89227828	liver	carcinoma	Deletion - Frameshift
c.1185T>C; p.S395S; 11:89284773-89284773	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.48C>T; p.S16S; 11:89178001-89178001	liver	carcinoma	Substitution - coding silent
c.552A>C; p.S184S; 11:89178505-89178505	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.568G>A; p.G190R; 11:89178521-89178521	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1064C>T; p.A355V; 11:89227850-89227850	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.756G>A; p.M252I; 11:89178709-89178709	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.959T>G; p.F320C; 11:89191341-89191341	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.246C>T; p.S82S; 11:89178199-89178199	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1367-3C>T; p.?; 11:89295140-89295140	skin; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.804C>A; p.F268L; 11:89178757-89178757	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.191C>A; p.P64Q; 11:89178144-89178144	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1495C>T; p.L499L; 11:89295271-89295271	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.955G>T; p.E319*; 11:89191337-89191337	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.783C>G; p.N261K; 11:89178736-89178736	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1501C>T; p.R501C; 11:89295277-89295277	skin	malignant_melanoma	Substitution - Missense
c.415A>C; p.T139P; 11:89178368-89178368	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.575C>A; p.S192Y; 11:89178528-89178528	breast	carcinoma	Substitution - Missense
c.425A>T; p.K142M; 11:89178378-89178378	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.34A>T; p.S12C; 11:89177987-89177987	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.151G>A; p.G51S; 11:89178104-89178104	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.236C>T; p.S79L; 11:89178189-89178189	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.236C>T; p.S79L; 11:89178189-89178189	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.236C>T; p.S79L; 11:89178189-89178189	large_intestine; colon	carcinoma	Substitution - Missense
c.1343A>T; p.D448V; 11:89284931-89284931	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.236C>T; p.S79L; 11:89178189-89178189	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.410A>G; p.Y137C; 11:89178363-89178363	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.49G>A; p.A17T; 11:89178002-89178002	liver	carcinoma	Substitution - Missense
c.462G>A; p.G154G; 11:89178415-89178415	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.410A>G; p.Y137C; 11:89178363-89178363	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.49G>A; p.A17T; 11:89178002-89178002	pancreas	carcinoma	Substitution - Missense
c.90G>A; p.L30L; 11:89178043-89178043	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.892C>T; p.R298W; 11:89191274-89191274	liver	carcinoma	Substitution - Missense
c.892C>T; p.R298W; 11:89191274-89191274	liver	carcinoma	Substitution - Missense
c.1037G>T; p.G346V; 11:89227823-89227823	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1369C>A; p.P457T; 11:89295145-89295145	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.494C>A; p.P165H; 11:89178447-89178447	lung	carcinoma; large_cell_carcinoma	Substitution - Missense
c.928C>G; p.P310A; 11:89191310-89191310	pancreas	carcinoma	Substitution - Missense
c.1103T>A; p.I368N; 11:89227889-89227889	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.191C>G; p.P64R; 11:89178144-89178144	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.695C>T; p.T232I; 11:89178648-89178648	kidney	other; neoplasm	Substitution - Missense
c.1440G>T; p.G480G; 11:89295216-89295216	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1152T>C; p.P384P; 11:89227938-89227938	liver	carcinoma	Substitution - coding silent
c.1086G>A; p.M362I; 11:89227872-89227872	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.963C>A; p.C321*; 11:89191345-89191345	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1166A>G; p.H389R; 11:89227952-89227952	pancreas	carcinoma	Substitution - Missense
c.1152T>C; p.P384P; 11:89227938-89227938	liver	carcinoma	Substitution - coding silent
c.1086G>A; p.M362I; 11:89227872-89227872	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1205G>A; p.R402Q; 11:89284793-89284793	skin	malignant_melanoma	Substitution - Missense
c.1205G>A; p.R402Q; 11:89284793-89284793	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.166C>T; p.Q56*; 11:89178119-89178119	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1346A>G; p.Y449C; 11:89284934-89284934	pancreas	carcinoma	Substitution - Missense
c.235T>C; p.S79P; 11:89178188-89178188	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.548T>C; p.V183A; 11:89178501-89178501	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1172C>A; p.A391E; 11:89227958-89227958	liver	carcinoma	Substitution - Missense
c.1247C>T; p.A416V; 11:89284835-89284835	breast	carcinoma	Substitution - Missense
c.902C>T; p.P301L; 11:89191284-89191284	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1172C>A; p.A391E; 11:89227958-89227958	liver	carcinoma	Substitution - Missense
c.902C>T; p.P301L; 11:89191284-89191284	skin	malignant_melanoma	Substitution - Missense
c.1227A>C; p.E409D; 11:89284815-89284815	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.373G>A; p.D125N; 11:89178326-89178326	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.362G>T; p.R121I; 11:89178315-89178315	breast	carcinoma	Substitution - Missense
c.373G>A; p.D125N; 11:89178326-89178326	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1354C>A; p.L452I; 11:89284942-89284942	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.715C>T; p.R239W; 11:89178668-89178668	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1354C>A; p.L452I; 11:89284942-89284942	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.124G>C; p.D42H; 11:89178077-89178077	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.805T>G; p.F269V; 11:89178758-89178758	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.805T>G; p.F269V; 11:89178758-89178758	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.875C>T; p.T292M; 11:89191257-89191257	upper_aerodigestive_tract; sinonasal_and_nasal_cavity	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.950A>G; p.D317G; 11:89191332-89191332	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.174C>T; p.I58I; 11:89178127-89178127	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1477G>T; p.A493S; 11:89295253-89295253	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.950A>G; p.D317G; 11:89191332-89191332	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.950A>G; p.D317G; 11:89191332-89191332	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1058G>A; p.G353E; 11:89227844-89227844	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.535A>T; p.M179L; 11:89178488-89178488	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1147G>A; p.D383N; 11:89227933-89227933	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1126C>G; p.Q376E; 11:89227912-89227912	central_nervous_system; brain	glioma	Substitution - Missense
c.621T>C; p.F207F; 11:89178574-89178574	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.383C>G; p.A128G; 11:89178336-89178336	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.120C>G; p.S40R; 11:89178073-89178073	breast	carcinoma	Substitution - Missense
c.460G>T; p.G154W; 11:89178413-89178413	prostate	carcinoma	Substitution - Missense
c.399_400insT; p.A136fs*33; 11:89178352-89178353	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.1355T>A; p.L452Q; 11:89284943-89284943	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.610G>A; p.A204T; 11:89178563-89178563	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.113C>A; p.P38Q; 11:89178066-89178066	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.784T>G; p.L262V; 11:89178737-89178737	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.176T>A; p.L59H; 11:89178129-89178129	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.432C>A; p.T144T; 11:89178385-89178385	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.582C>T; p.I194I; 11:89178535-89178535	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.893G>A; p.R298Q; 11:89191275-89191275	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.901C>T; p.P301S; 11:89191283-89191283	skin	malignant_melanoma	Substitution - Missense
c.433A>G; p.I145V; 11:89178386-89178386	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1107T>C; p.Y369Y; 11:89227893-89227893	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1159C>T; p.L387F; 11:89227945-89227945	breast	carcinoma	Substitution - Missense
c.1203C>T; p.L401L; 11:89284791-89284791	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.725A>C; p.E242A; 11:89178678-89178678	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense

COSMIC somatic mutation [Top]