Cancer metastasis gene database Home
Cancer metastasis database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

6713

Name

SQLE

Synonymous

squalene epoxidase;SQLE;squalene epoxidase

Definition

SE|squalene monooxygenase

Position

8q24.1

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.1480T>C; p.Y494H; 8:125020819-125020819

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.104_106delTCC; p.L36delL; 8:124999507-124999509

 lungcarcinoma; adenocarcinomaDeletion - In frame

c.1459C>A; p.L487I; 8:125020798-125020798

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1191A>T; p.S397S; 8:125011619-125011619

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.882C>T; p.S294S; 8:125009030-125009030

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.9T>C; p.T3T; 8:124999412-124999412

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.987G>C; p.P329P; 8:125009222-125009222

 breastcarcinomaSubstitution - coding silent

c.859C>T; p.L287F; 8:125009007-125009007

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1681A>G; p.I561V; 8:125021901-125021901

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.129C>T; p.S43S; 8:124999532-124999532

 skinmalignant_melanomaSubstitution - coding silent

c.301G>T; p.G101*; 8:125003185-125003185

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.1062G>A; p.R354R; 8:125009297-125009297

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1552G>A; p.V518I; 8:125021772-125021772

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1091T>A; p.I364N; 8:125009326-125009326

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.371C>T; p.P124L; 8:125003255-125003255

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.463G>A; p.D155N; 8:125003347-125003347

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.371C>T; p.P124L; 8:125003255-125003255

 upper_aerodigestive_tract; mouthcarcinomaSubstitution - Missense

c.1603T>C; p.F535L; 8:125021823-125021823

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1357T>C; p.S453P; 8:125018640-125018640

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.172C>T; p.Q58*; 8:124999575-124999575

 stomachcarcinoma; adenocarcinomaSubstitution - Nonsense

c.1357T>C; p.S453P; 8:125018640-125018640

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.269A>C; p.K90T; 8:124999672-124999672

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.699C>T; p.L233L; 8:125005679-125005679

 NSNSSubstitution - coding silent

c.396C>T; p.G132G; 8:125003280-125003280

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.1637C>T; p.A546V; 8:125021857-125021857

 oesophagus; middle_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.893A>G; p.N298S; 8:125009041-125009041

 livercarcinomaSubstitution - Missense

c.871T>C; p.F291L; 8:125009019-125009019

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.514T>C; p.Y172H; 8:125003398-125003398

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.296G>A; p.R99K; 8:125003180-125003180

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1160C>T; p.S387F; 8:125011588-125011588

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1562G>A; p.G521E; 8:125021782-125021782

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.384C>T; p.I128I; 8:125003268-125003268

 skinmalignant_melanomaSubstitution - coding silent

c.32C>A; p.T11N; 8:124999435-124999435

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1208_1210delTTC; p.L406delL; 8:125018062-125018064

 breastcarcinomaDeletion - In frame

c.1006C>T; p.Q336*; 8:125009241-125009241

 oesophaguscarcinomaSubstitution - Nonsense

c.1532+1G>A; p.?; 8:125020872-125020872

 thyroidcarcinomaUnknown

c.900T>C; p.V300V; 8:125009048-125009048

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1437C>A; p.A479A; 8:125018720-125018720

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1437C>A; p.A479A; 8:125018720-125018720

 upper_aerodigestive_tract; mouthcarcinomaSubstitution - coding silent

c.1699T>G; p.S567A; 8:125021919-125021919

 livercarcinomaSubstitution - Missense

c.1699T>G; p.S567A; 8:125021919-125021919

 livercarcinomaSubstitution - Missense

c.1590C>T; p.A530A; 8:125021810-125021810

 stomachcarcinoma; diffuse_adenocarcinomaSubstitution - coding silent

c.626C>T; p.P209L; 8:125005606-125005606

 skinmalignant_melanomaSubstitution - Missense

c.508G>A; p.G170S; 8:125003392-125003392

 skinmalignant_melanomaSubstitution - Missense

c.736A>G; p.I246V; 8:125007401-125007401

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.62T>C; p.I21T; 8:124999465-124999465

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1225G>A; p.A409T; 8:125018079-125018079

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1225G>A; p.A409T; 8:125018079-125018079

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.133C>T; p.R45C; 8:124999536-124999536

 autonomic_ganglianeuroblastomaSubstitution - Missense

c.1497C>T; p.G499G; 8:125020836-125020836

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.1497C>T; p.G499G; 8:125020836-125020836

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.1497C>T; p.G499G; 8:125020836-125020836

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.905T>C; p.V302A; 8:125009053-125009053

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.986C>T; p.P329L; 8:125009221-125009221

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.397G>A; p.V133M; 8:125003281-125003281

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.397G>A; p.V133M; 8:125003281-125003281

 breastcarcinomaSubstitution - Missense

c.778G>A; p.V260M; 8:125007443-125007443

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.985C>T; p.P329S; 8:125009220-125009220

 skinmalignant_melanomaSubstitution - Missense

c.9T>A; p.T3T; 8:124999412-124999412

 ovarycarcinoma; serous_carcinomaSubstitution - coding silent

c.725A>C; p.N242T; 8:125005705-125005705

 pancreascarcinomaSubstitution - Missense

c.837A>G; p.P279P; 8:125008985-125008985

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.355T>C; p.S119P; 8:125003239-125003239

 prostatecarcinomaSubstitution - Missense

c.1150C>T; p.H384Y; 8:125011578-125011578

 breastcarcinoma; HER-positive_carcinomaSubstitution - Missense

c.558T>G; p.G186G; 8:125005538-125005538

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.625C>T; p.P209S; 8:125005605-125005605

 skinmalignant_melanomaSubstitution - Missense

c.1563A>T; p.G521G; 8:125021783-125021783

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.1580C>T; p.A527V; 8:125021800-125021800

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.555A>G; p.E185E; 8:125005535-125005535

 bone; femurEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.248delC; p.P85fs*25; 8:124999651-124999651

 large_intestinecarcinoma; adenocarcinomaDeletion - Frameshift

c.248delC; p.P85fs*25; 8:124999651-124999651

 large_intestinecarcinoma; adenocarcinomaDeletion - Frameshift