| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 6713 |
Name | SQLE |
Synonym | squalene epoxidase;SQLE;squalene epoxidase |
Definition | SE|squalene monooxygenase |
Position | 8q24.1 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | cholesterol biosynthesis II (via 24,25-dihydrolanosterol);BioCyc;PWY66-3 |
Pathway | cholesterol biosynthesis I;BioCyc;PWY66-341 |
Pathway | epoxysqualene biosynthesis;BioCyc;PWY-5670 |
Pathway | Metabolic pathways;KEGG PATHWAY;hsa01100 |
Pathway | Steroid biosynthesis;KEGG PATHWAY;hsa00100 |
Pathway | Cholesterol biosynthesis;PANTHER;P00014 |
Pathway | Metabolism of lipids and lipoproteins;Reactome;REACT:22258 |
Pathway | cholesterol biosynthesis III (via desmosterol);BioCyc;PWY66-4 |
External Links | |
Links to Entrez Gene | 6713 |
Links to all GeneRIF Items | 6713 |
Links to iHOP | 6713 |
Sequence Information | |
Nucleotide Sequence | >6713 : length: 2989 GTCTGGGCCGAGCCCGCCCAGCTGGCTGAGACGCGTGGAGCCTGGCGGCGAGTGGGGGCG TGCGACGGTTACTCTGGTTACTGGGGCCGCGCCGCGCTGGCGAGAGCCGCCGCCCGCGAG GGATGCTGGTGAGGAAGCCGTCGGGAGCCGCCGCCGCCATCTGAGGGAGGTACCCTGGAA ACCACCTTTTATCGGTGGGGAAGTGCAGTCGCGGTGGGCGGCTCTGGGGGCCAGCGAAAC GGGAGGCCTCTAAATCTTTAGGTTGGGGCTGCATTGCCCTGGAGCCGCACTCTTGAGTCC GAGGCCATCTTTTGTTGGAGAAGGCGTCGGCGTTGGCGTTTTCCCGAGGTTGGGCTGTAC AGTGTCTCCGTCCGCGGAAAAAGAAGCCTCTGAACCCGCGCCGGCCCGCAGCCCCCGTGC CTTCCGGCCGCTGCTCGCCGTCGCCAGAGGCTAGGCCACGTTTCCCCCAGTGCCGAGGTG TTTCTGTGACCCTCCCTCCACTCCCATTCCCTTCTGAAAGGGCACCTGCTCTTGGTGAGA AAAGAAATTATAGCACGAAGAGCCAGTATCAGAAGAGTATCCATCACCCGCAGCAACCGC TCAGGGAACACCATCAAAAAAGAAAAAAAGGGAATATCTGGATTTCCTGGGCGAGGAGGA GCGAGTCTGCTCGGGAGCTGTTCCAGCAGGCGATTTTTAAATACTGCTTTCTACGCCCTA TACAACTTGGCTTCACATACTTTTACACTAACTTTATATGATTTTTAAAAACTGGTCTGA TCGGACTTCTCGTCCTGGGACACTGTTTACTGGAGTCTGGCCGGCTCTCCGTGCTCCTCT TGGTACCTCATTTTGGGGAGAACCTTAAACCCACTCGAGCAGATAATCTCCGCCTTGACC GGTGCCACCAAAGAAGCCTTGGAACCATGTGGACTTTTCTGGGCATTGCCACTTTCACCT ATTTTTATAAGAAGTTCGGGGACTTCATCACTTTGGCCAACAGGGAGGTCCTGTTGTGCG TGCTGGTGTTCCTCTCGCTGGGCCTGGTGCTCTCCTACCGCTGTCGCCACCGAAACGGGG GTCTCCTCGGGCGCCAGCAGAGCGGCTCCCAGTTCGCCCTCTTCTCGGATATTCTCTCAG GCCTGCCTTTCATTGGCTTCTTCTGGGCCAAATCCCCCCCTGAATCAGAAAATAAGGAGC AGCTCGAGGCCAGGAGGCGCAGAAAAGGAACCAATATTTCAGAAACAAGCTTAATAGGAA CAGCTGCCTGTACATCAACATCTTCTCAGAATGACCCAGAAGTTATCATCGTGGGAGCTG GCGTGCTTGGCTCTGCTTTGGCAGCTGTGCTTTCCAGAGATGGAAGAAAGGTGACAGTCA TTGAGAGAGACTTAAAAGAGCCTGACAGAATAGTTGGAGAATTCCTGCAGCCGGGTGGTT ATCATGTTCTCAAAGACCTTGGTCTTGGAGATACAGTGGAAGGTCTTGATGCCCAGGTTG TAAATGGTTACATGATTCATGATCAGGAAAGCAAATCAGAGGTTCAGATTCCTTACCCTC TGTCAGAAAACAATCAAGTGCAGAGTGGAAGAGCTTTCCATCACGGAAGATTCATCATGA GTCTCCGGAAAGCAGCTATGGCAGAGCCCAATGCAAAGTTTATTGAAGGTGTTGTGTTAC AGTTATTAGAGGAAGATGATGTTGTGATGGGAGTTCAGTACAAGGATAAAGAGACTGGAG ATATCAAGGAACTCCATGCTCCACTGACTGTTGTTGCAGATGGGCTTTTCTCCAAGTTCA GGAAAAGCCTGGTCTCCAATAAAGTTTCTGTATCATCTCATTTTGTTGGCTTTCTTATGA AGAATGCACCACAGTTTAAAGCAAATCATGCTGAACTTATTTTAGCTAACCCGAGTCCAG TTCTCATCTACCAGATTTCATCCAGTGAAACTCGAGTACTTGTTGACATTAGAGGAGAAA TGCCAAGGAATTTAAGAGAATACATGGTTGAAAAAATTTACCCACAAATACCTGATCACC TGAAAGAACCATTCTTAGAAGCCACTGACAATTCTCATCTGAGGTCCATGCCAGCAAGCT TCCTTCCTCCTTCATCAGTGAAGAAACGAGGTGTTCTTCTTTTGGGAGACGCATATAATA TGAGGCATCCACTTACTGGTGGAGGAATGACTGTTGCTTTTAAAGATATAAAACTATGGA GAAAACTGCTAAAGGGTATCCCTGACCTTTATGATGATGCAGCTATTTTCGAGGCCAAAA AATCATTTTACTGGGCAAGAAAAACATCTCATTCCTTTGTCGTGAATATCCTTGCTCAGG CTCTTTATGAATTATTTTCTGCCACAGATGATTCCCTGCATCAACTAAGAAAAGCCTGTT TTCTTTATTTCAAACTTGGTGGCGAATGTGTTGCGGGTCCTGTTGGGCTGCTTTCTGTAT TGTCTCCTAACCCTCTAGTTTTAATTGGACACTTCTTTGCTGTTGCAATCTATGCCGTGT ATTTTTGCTTTAAGTCAGAACCTTGGATTACAAAACCTCGAGCCCTTCTCAGTAGTGGTG CTGTATTGTACAAAGCGTGTTCTGTAATATTTCCTCTAATTTACTCAGAAATGAAGTATA TGGTTCATTAAGCTTAAAGGGGAACCATTTGTGAATGAATATTTGGAACTTACCAAGTCC TAAGAGACTTTTGGAAGAGGATATATATAGCATAGTACCATACCACTTATAAAGTGGAAA CTCTTGGACCAAGATTTGGATTAATTTGTTTTTGAAGTTTTTTGTATATAAATATGTAAA TACATGCTTTAATTTGCAATTTAAAATGAAGGGGTTAAATAAGTTAGACATTTAAAAGAA ATGATTGTTACCATAAATTAGTGCTAATGCTGAGGAGAACTACAGTTTTTCTTTTGAATT TAGTATTTGAGATGAGTTGTTGGGACATGCAAATAAAATGAAGAATGAA |
Protein Sequence | >6713 : length: 574 MWTFLGIATFTYFYKKFGDFITLANREVLLCVLVFLSLGLVLSYRCRHRNGGLLGRQQSG SQFALFSDILSGLPFIGFFWAKSPPESENKEQLEARRRRKGTNISETSLIGTAACTSTSS QNDPEVIIVGAGVLGSALAAVLSRDGRKVTVIERDLKEPDRIVGEFLQPGGYHVLKDLGL GDTVEGLDAQVVNGYMIHDQESKSEVQIPYPLSENNQVQSGRAFHHGRFIMSLRKAAMAE PNAKFIEGVVLQLLEEDDVVMGVQYKDKETGDIKELHAPLTVVADGLFSKFRKSLVSNKV SVSSHFVGFLMKNAPQFKANHAELILANPSPVLIYQISSSETRVLVDIRGEMPRNLREYM VEKIYPQIPDHLKEPFLEATDNSHLRSMPASFLPPSSVKKRGVLLLGDAYNMRHPLTGGG MTVAFKDIKLWRKLLKGIPDLYDDAAIFEAKKSFYWARKTSHSFVVNILAQALYELFSAT DDSLHQLRKACFLYFKLGGECVAGPVGLLSVLSPNPLVLIGHFFAVAIYAVYFCFKSEPW ITKPRALLSSGAVLYKACSVIFPLIYSEMKYMVH |