Cancer metastasis gene database Home
Cancer metastasis database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

4356

Name

MPP3

Synonymous

membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3);MPP3;membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)

Definition

MAGUK p55 subfamily member 3|discs large homolog 3|discs, large homolog 3|membrane protein palmitoylated 3

Position

17q21.31

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.1170G>C; p.L390L; 17:43814201-43814201

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.613C>T; p.Q205*; 17:43824002-43824002

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_leukaemiaSubstitution - Nonsense

c.668G>A; p.R223H; 17:43823947-43823947

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.534C>T; p.H178H; 17:43825831-43825831

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.574C>T; p.L192L; 17:43825791-43825791

 skinmalignant_melanomaSubstitution - coding silent

c.1544C>T; p.P515L; 17:43808993-43808993

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.568G>A; p.A190T; 17:43825797-43825797

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.568G>A; p.A190T; 17:43825797-43825797

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.568G>A; p.A190T; 17:43825797-43825797

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.157C>A; p.L53I; 17:43831309-43831309

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.816G>A; p.Q272Q; 17:43820927-43820927

 skinmalignant_melanomaSubstitution - coding silent

c.294G>A; p.P98P; 17:43830036-43830036

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.619C>T; p.Q207*; 17:43823996-43823996

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.1727C>T; p.T576I; 17:43801732-43801732

 skinmalignant_melanomaSubstitution - Missense

c.250G>A; p.V84M; 17:43830080-43830080

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.131G>A; p.S44N; 17:43831572-43831572

 breastcarcinomaSubstitution - Missense

c.457C>T; p.R153W; 17:43827817-43827817

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.457C>T; p.R153W; 17:43827817-43827817

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.1158C>T; p.R386R; 17:43814213-43814213

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.918G>A; p.P306P; 17:43818074-43818074

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1246G>A; p.A416T; 17:43814020-43814020

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1380T>C; p.N460N; 17:43810885-43810885

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1656G>A; p.V552V; 17:43801803-43801803

 skin; upper_legmalignant_melanomaSubstitution - coding silent

c.1471C>T; p.L491L; 17:43809066-43809066

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1538C>T; p.T513M; 17:43808999-43808999

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.792C>T; p.S264S; 17:43820951-43820951

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1538C>T; p.T513M; 17:43808999-43808999

 pancreascarcinomaSubstitution - Missense

c.1538C>T; p.T513M; 17:43808999-43808999

 pancreascarcinomaSubstitution - Missense

c.1538C>T; p.T513M; 17:43808999-43808999

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.592G>A; p.E198K; 17:43825773-43825773

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1143C>A; p.P381P; 17:43814228-43814228

 skinmalignant_melanomaSubstitution - coding silent

c.1473G>T; p.L491L; 17:43809064-43809064

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.695G>A; p.R232H; 17:43821048-43821048

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.249C>T; p.S83S; 17:43830081-43830081

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.303+4G>A; p.?; 17:43830023-43830023

 oesophagus; lower_thirdcarcinoma; adenocarcinomaUnknown

c.695G>A; p.R232H; 17:43821048-43821048

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.357C>T; p.L119L; 17:43829738-43829738

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.1345A>C; p.N449H; 17:43811116-43811116

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.1241G>T; p.G414V; 17:43814025-43814025

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1097C>T; p.P366L; 17:43814274-43814274

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.571G>C; p.V191L; 17:43825794-43825794

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1156C>T; p.R386C; 17:43814215-43814215

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1255C>T; p.H419Y; 17:43814011-43814011

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.259G>A; p.D87N; 17:43830071-43830071

 haematopoietic_and_lymphoid_tissue; central_nervous_systemlymphoid_neoplasm; primary_central_nervous_system_lymphomaSubstitution - Missense

c.567C>T; p.I189I; 17:43825798-43825798

 skinmalignant_melanomaSubstitution - coding silent

c.289A>C; p.T97P; 17:43830041-43830041

 prostatecarcinomaSubstitution - Missense

c.728G>A; p.R243Q; 17:43821015-43821015

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.144+1G>A; p.?; 17:43831558-43831558

 autonomic_ganglianeuroblastomaUnknown

c.25G>T; p.G9C; 17:43831882-43831882

 breastcarcinomaSubstitution - Missense

c.1265G>C; p.R422T; 17:43811196-43811196

 breastcarcinomaSubstitution - Missense

c.645C>T; p.I215I; 17:43823970-43823970

 skinmalignant_melanomaSubstitution - coding silent

c.167A>G; p.Y56C; 17:43831299-43831299

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1729C>T; p.H577Y; 17:43801730-43801730

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.730G>A; p.A244T; 17:43821013-43821013

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.730G>A; p.A244T; 17:43821013-43821013

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.1009+6T>C; p.?; 17:43816032-43816032

 livercarcinomaUnknown

c.771G>A; p.R257R; 17:43820972-43820972

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.21C>G; p.D7E; 17:43831886-43831886

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.1651G>A; p.A551T; 17:43801808-43801808

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1161G>T; p.L387L; 17:43814210-43814210

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.549C>G; p.L183L; 17:43825816-43825816

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.470C>T; p.S157L; 17:43827804-43827804

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1189C>T; p.R397*; 17:43814077-43814077

 pancreascarcinomaSubstitution - Nonsense

c.367C>T; p.P123S; 17:43829728-43829728

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1472T>C; p.L491P; 17:43809065-43809065

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1353C>A; p.F451L; 17:43810912-43810912

 breastcarcinomaSubstitution - Missense

c.1170G>T; p.L390L; 17:43814201-43814201

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.904G>T; p.A302S; 17:43818088-43818088

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.360G>A; p.P120P; 17:43829735-43829735

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1606G>A; p.A536T; 17:43801853-43801853

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1080C>T; p.S360S; 17:43814291-43814291

 skinmalignant_melanomaSubstitution - coding silent

c.688T>A; p.F230I; 17:43821055-43821055

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.327G>A; p.T109T; 17:43829768-43829768

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.327G>A; p.T109T; 17:43829768-43829768

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1427delA; p.N476fs*13; 17:43810838-43810838

 NSmalignant_melanomaDeletion - Frameshift

c.348_349CC>TT; p.P117S; 17:43829746-43829747

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.19G>C; p.D7H; 17:43831888-43831888

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1049G>A; p.R350K; 17:43814322-43814322

 skinmalignant_melanomaSubstitution - Missense

c.1191A>C; p.R397R; 17:43814075-43814075

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.288C>T; p.S96S; 17:43830042-43830042

 skinmalignant_melanomaSubstitution - coding silent

c.1753A>G; p.R585G; 17:43801706-43801706

 haematopoietic_and_lymphoid_tissue; lymph_nodelymphoid_neoplasm; acute_lymphoblastic_leukaemiaSubstitution - Missense

c.1753A>G; p.R585G; 17:43801706-43801706

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.610G>A; p.A204T; 17:43824005-43824005

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.379G>A; p.D127N; 17:43829716-43829716

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1275G>T; p.K425N; 17:43811186-43811186

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1708G>C; p.E570Q; 17:43801751-43801751

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.1242C>T; p.G414G; 17:43814024-43814024

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1242C>T; p.G414G; 17:43814024-43814024

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1708G>C; p.E570Q; 17:43801751-43801751

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense