Entrez Gene

Basic Information
Gene ID	4059
Name	BCAM
Synonymous	basal cell adhesion molecule (Lutheran blood group);BCAM;basal cell adhesion molecule (Lutheran blood group)
Definition	Auberger b antigen\|B-CAM cell surface glycoprotein\|B-cell adhesion molecule\|F8/G253 antigen\|antigen identified by monoclonal antibody F8\|basal cell adhesion molecule\|basal cell adhesion molecule (Lu and Au blood groups)\|glycoprotein 95kDa
Position	19q13.2
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.906G>A; p.T302T; 19:44814273-44814273	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.906G>A; p.T302T; 19:44814273-44814273	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1155C>T; p.S385S; 19:44818598-44818598	skin	malignant_melanoma	Substitution - coding silent
c.875delG; p.D294fs*21; 19:44814242-44814242	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.167C>T; p.T56M; 19:44811309-44811309	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.167C>T; p.T56M; 19:44811309-44811309	stomach	adenocarcinoma	Substitution - Missense
c.1072G>A; p.V358M; 19:44814754-44814754	liver	carcinoma	Substitution - Missense
c.1072G>A; p.V358M; 19:44814754-44814754	liver	carcinoma	Substitution - Missense
c.1550G>A; p.R517H; 19:44819422-44819422	pancreas	carcinoma	Substitution - Missense
c.711C>T; p.C237C; 19:44813547-44813547	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.711C>T; p.C237C; 19:44813547-44813547	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1413C>A; p.L471L; 19:44819132-44819132	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.551C>T; p.T184M; 19:44813296-44813296	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1402G>A; p.E468K; 19:44819121-44819121	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.577G>T; p.E193*; 19:44813322-44813322	lung	carcinoma; small_cell_carcinoma	Substitution - Nonsense
c.715G>A; p.A239T; 19:44813551-44813551	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.746G>A; p.G249D; 19:44813582-44813582	skin	malignant_melanoma	Substitution - Missense
c.715G>A; p.A239T; 19:44813551-44813551	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1183C>T; p.R395C; 19:44818626-44818626	bone; extraskeletal	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.1093G>A; p.E365K; 19:44818536-44818536	skin	malignant_melanoma	Substitution - Missense
c.364G>T; p.D122Y; 19:44812322-44812322	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.376G>A; p.V126M; 19:44812334-44812334	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.10C>T; p.P4S; 19:44809134-44809134	liver	carcinoma	Substitution - Missense
c.10C>T; p.P4S; 19:44809134-44809134	liver	carcinoma	Substitution - Missense
c.1026C>T; p.Y342Y; 19:44814708-44814708	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.809G>A; p.W270*; 19:44814176-44814176	ovary	carcinoma; serous_carcinoma	Substitution - Nonsense
c.415G>A; p.A139T; 19:44812373-44812373	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1090delC; p.L364fs*13; 19:44818533-44818533	large_intestine; colon	carcinoma	Deletion - Frameshift
c.1362A>T; p.E454D; 19:44819081-44819081	skin	malignant_melanoma	Substitution - Missense
c.489G>A; p.E163E; 19:44812533-44812533	skin	malignant_melanoma	Substitution - coding silent
c.1739G>A; p.R580H; 19:44819702-44819702	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1248C>T; p.F416F; 19:44818794-44818794	skin	malignant_melanoma	Substitution - coding silent
c.1349T>C; p.L450P; 19:44819068-44819068	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1879G>A; p.E627K; 19:44820820-44820820	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1143C>A; p.V381V; 19:44818586-44818586	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.1611C>T; p.F537F; 19:44819483-44819483	skin	malignant_melanoma	Substitution - coding silent
c.1611C>T; p.F537F; 19:44819483-44819483	skin; trunk	malignant_melanoma; nodular	Substitution - coding silent
c.986G>A; p.R329Q; 19:44814668-44814668	prostate	carcinoma	Substitution - Missense
c.905C>T; p.T302M; 19:44814272-44814272	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.375C>T; p.C125C; 19:44812333-44812333	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1742A>T; p.Q581L; 19:44819705-44819705	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1663G>T; p.A555S; 19:44819626-44819626	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.898G>A; p.E300K; 19:44814265-44814265	skin	malignant_melanoma	Substitution - Missense
c.1058C>T; p.T353M; 19:44814740-44814740	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1086delC; p.L364fs*13; 19:44818529-44818529	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.846C>T; p.R282R; 19:44814213-44814213	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1774G>A; p.E592K; 19:44820715-44820715	skin	malignant_melanoma	Substitution - Missense
c.280G>A; p.D94N; 19:44812238-44812238	skin	malignant_melanoma	Substitution - Missense
c.1340C>T; p.S447L; 19:44819059-44819059	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.280G>A; p.D94N; 19:44812238-44812238	stomach	adenocarcinoma	Substitution - Missense
c.1485A>G; p.P495P; 19:44819357-44819357	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1316A>T; p.N439I; 19:44818862-44818862	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.673C>T; p.R225W; 19:44813509-44813509	pancreas	carcinoma	Substitution - Missense
c.538G>A; p.A180T; 19:44813283-44813283	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.100C>T; p.R34C; 19:44811242-44811242	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.92C>T; p.A31V; 19:44811234-44811234	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1766C>T; p.P589L; 19:44820707-44820707	pancreas	carcinoma	Substitution - Missense
c.1750G>A; p.E584K; 19:44819713-44819713	skin	malignant_melanoma	Substitution - Missense
c.976G>T; p.G326*; 19:44814658-44814658	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1748G>T; p.R583L; 19:44819711-44819711	lung; middle_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1748G>T; p.R583L; 19:44819711-44819711	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.1627C>T; p.Q543*; 19:44819590-44819590	skin	malignant_melanoma	Substitution - Nonsense
c.508G>A; p.A170T; 19:44813253-44813253	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1524C>A; p.T508T; 19:44819396-44819396	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.475C>A; p.L159M; 19:44812519-44812519	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1341G>A; p.S447S; 19:44819060-44819060	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1341G>A; p.S447S; 19:44819060-44819060	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1490C>T; p.P497L; 19:44819362-44819362	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.1644A>G; p.G548G; 19:44819607-44819607	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.229C>T; p.R77C; 19:44812187-44812187	skin	malignant_melanoma	Substitution - Missense
c.1435C>T; p.P479S; 19:44819154-44819154	skin	malignant_melanoma	Substitution - Missense
c.850G>C; p.G284R; 19:44814217-44814217	skin	malignant_melanoma	Substitution - Missense
c.590A>G; p.E197G; 19:44813335-44813335	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.577G>A; p.E193K; 19:44813322-44813322	skin	malignant_melanoma	Substitution - Missense
c.1020G>A; p.E340E; 19:44814702-44814702	skin	malignant_melanoma	Substitution - coding silent
c.1238C>T; p.S413F; 19:44818784-44818784	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1238C>T; p.S413F; 19:44818784-44818784	central_nervous_system; brain	glioma	Substitution - Missense
c.1238C>T; p.S413F; 19:44818784-44818784	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1788C>A; p.S596R; 19:44820729-44820729	central_nervous_system; brain	glioma	Substitution - Missense
c.879G>A; p.G293G; 19:44814246-44814246	thyroid	carcinoma	Substitution - coding silent
c.990C>A; p.G330G; 19:44814672-44814672	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.535_536CC>TT; p.P179L; 19:44813280-44813281	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.416C>T; p.A139V; 19:44812374-44812374	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.932A>G; p.E311G; 19:44814614-44814614	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1429G>A; p.G477S; 19:44819148-44819148	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1358C>T; p.A453V; 19:44819077-44819077	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1358C>T; p.A453V; 19:44819077-44819077	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.1489C>T; p.P497S; 19:44819361-44819361	skin	malignant_melanoma	Substitution - Missense
c.1358C>T; p.A453V; 19:44819077-44819077	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1206_1207CC>TT; p.(=); 19:44818752-44818753	skin; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.418C>T; p.R140W; 19:44812376-44812376	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.292C>T; p.R98C; 19:44812250-44812250	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.433+3A>T; p.?; 19:44812394-44812394	liver	carcinoma; hepatocellular_carcinoma	Unknown
c.1747C>T; p.R583W; 19:44819710-44819710	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1747C>T; p.R583W; 19:44819710-44819710	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1747C>T; p.R583W; 19:44819710-44819710	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1763C>T; p.P588L; 19:44819726-44819726	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.1580C>T; p.P527L; 19:44819452-44819452	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1671C>T; p.S557S; 19:44819634-44819634	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1464delG; p.G490fs*14; 19:44819183-44819183	stomach	adenocarcinoma	Deletion - Frameshift
c.1615A>G; p.T539A; 19:44819487-44819487	prostate	adenoma	Substitution - Missense
c.825C>T; p.S275S; 19:44814192-44814192	skin	malignant_melanoma	Substitution - coding silent
c.472A>G; p.T158A; 19:44812516-44812516	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.714C>T; p.A238A; 19:44813550-44813550	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.714C>T; p.A238A; 19:44813550-44813550	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.714C>T; p.A238A; 19:44813550-44813550	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.287G>A; p.R96Q; 19:44812245-44812245	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1615A>G; p.T539A; 19:44819487-44819487	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1577A>G; p.N526S; 19:44819449-44819449	skin	malignant_melanoma	Substitution - Missense
c.361C>T; p.R121*; 19:44812319-44812319	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.85G>A; p.A29T; 19:44811227-44811227	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.530G>A; p.G177E; 19:44813275-44813275	skin	malignant_melanoma	Substitution - Missense
c.685G>A; p.D229N; 19:44813521-44813521	skin	malignant_melanoma	Substitution - Missense
c.1773G>A; p.G591G; 19:44820714-44820714	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.697G>A; p.A233T; 19:44813533-44813533	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1475C>T; p.P492L; 19:44819347-44819347	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.132G>A; p.M44I; 19:44811274-44811274	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1745G>A; p.R582Q; 19:44819708-44819708	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1745G>A; p.R582Q; 19:44819708-44819708	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1579C>T; p.P527S; 19:44819451-44819451	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.178G>A; p.D60N; 19:44811320-44811320	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1296G>A; p.P432P; 19:44818842-44818842	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.326G>A; p.R109H; 19:44812284-44812284	pancreas	carcinoma	Substitution - Missense
c.1399G>A; p.D467N; 19:44819118-44819118	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1249G>T; p.D417Y; 19:44818795-44818795	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1359G>A; p.A453A; 19:44819078-44819078	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.1143C>T; p.V381V; 19:44818586-44818586	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1143C>T; p.V381V; 19:44818586-44818586	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.914G>A; p.R305H; 19:44814281-44814281	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1359G>A; p.A453A; 19:44819078-44819078	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - coding silent
c.1653C>T; p.V551V; 19:44819616-44819616	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.379G>T; p.V127L; 19:44812337-44812337	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1632C>T; p.T544T; 19:44819595-44819595	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1556G>T; p.G519V; 19:44819428-44819428	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.956_957insG; p.N321fs*27; 19:44814638-44814639	large_intestine; caecum	carcinoma; adenocarcinoma	Insertion - Frameshift
c.1314G>T; p.Q438H; 19:44818860-44818860	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.611T>A; p.M204K; 19:44813447-44813447	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1144G>A; p.V382M; 19:44818587-44818587	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1738C>T; p.R580C; 19:44819701-44819701	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.749G>A; p.R250H; 19:44813585-44813585	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1738C>T; p.R580C; 19:44819701-44819701	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.392C>T; p.A131V; 19:44812350-44812350	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1069C>T; p.R357C; 19:44814751-44814751	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1695T>A; p.V565V; 19:44819658-44819658	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.1069C>T; p.R357C; 19:44814751-44814751	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.874_875insG; p.D294fs*16; 19:44814241-44814242	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.94G>A; p.E32K; 19:44811236-44811236	skin; abdomen	malignant_melanoma	Substitution - Missense
c.518A>G; p.N173S; 19:44813263-44813263	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.487G>A; p.E163K; 19:44812531-44812531	skin	malignant_melanoma	Substitution - Missense
c.1723delG; p.G576fs*20; 19:44819686-44819686	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.487G>A; p.E163K; 19:44812531-44812531	skin	malignant_melanoma	Substitution - Missense
c.1438G>T; p.D480Y; 19:44819157-44819157	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense

COSMIC somatic mutation [Top]