Cancer metastasis gene database Home
Cancer metastasis database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

2770

Name

GNAI1

Synonymous

guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1;GNAI1;guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1

Definition

Gi1 protein alpha subunit|adenylate cyclase-inhibiting G alpha protein|guanine nucleotide-binding protein G(i) subunit alpha-1

Position

7q21

Gene Type

protein-coding

COSMIC somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.246T>C; p.I82I; 7:80189174-80189174

 skinmalignant_melanomaSubstitution - coding silent

c.28A>T; p.K10*; 7:80135188-80135188

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Nonsense

c.928C>G; p.L310V; 7:80217356-80217356

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.362C>G; p.A121G; 7:80199283-80199283

 oesophaguscarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.642C>T; p.C214C; 7:80211020-80211020

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.405T>C; p.G135G; 7:80199326-80199326

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.691G>A; p.D231N; 7:80211069-80211069

 pancreascarcinomaSubstitution - Missense

c.302C>T; p.A101V; 7:80189230-80189230

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaSubstitution - Missense

c.302C>T; p.A101V; 7:80189230-80189230

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaSubstitution - Missense

c.302C>T; p.A101V; 7:80189230-80189230

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.302C>T; p.A101V; 7:80189230-80189230

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaSubstitution - Missense

c.194A>G; p.E65G; 7:80189122-80189122

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.771G>C; p.K257N; 7:80212766-80212766

 central_nervous_system; braingliomaSubstitution - Missense

c.392_393GG>TT; p.W131F; 7:80199313-80199314

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.814G>T; p.D272Y; 7:80212809-80212809

 livercarcinomaSubstitution - Missense

c.814G>T; p.D272Y; 7:80212809-80212809

 livercarcinomaSubstitution - Missense

c.613A>G; p.R205G; 7:80210991-80210991

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.659C>T; p.A220V; 7:80211037-80211037

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.659C>T; p.A220V; 7:80211037-80211037

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.162A>G; p.K54K; 7:80189090-80189090

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.724C>T; p.R242*; 7:80212719-80212719

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.902C>T; p.A301V; 7:80217330-80217330

 livercarcinomaSubstitution - Missense

c.658G>A; p.A220T; 7:80211036-80211036

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.954A>T; p.E318D; 7:80217382-80217382

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.943G>A; p.D315N; 7:80217371-80217371

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.1004delT; p.F336fs*4; 7:80217432-80217432

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.1062T>G; p.F354L; 7:80217490-80217490

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.278T>C; p.I93T; 7:80189206-80189206

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.278T>C; p.I93T; 7:80189206-80189206

 large_intestine; coloncarcinomaSubstitution - Missense

c.278T>C; p.I93T; 7:80189206-80189206

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.51G>C; p.K17N; 7:80135211-80135211

 skinmalignant_melanomaSubstitution - Missense

c.259G>A; p.A87T; 7:80189187-80189187

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.734A>G; p.E245G; 7:80212729-80212729

 livercarcinomaSubstitution - Missense

c.579T>C; p.D193D; 7:80203821-80203821

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.623G>A; p.R208Q; 7:80211001-80211001

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.578A>G; p.D193G; 7:80203820-80203820

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.364G>T; p.E122*; 7:80199285-80199285

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.304G>C; p.D102H; 7:80199225-80199225

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.730C>A; p.H244N; 7:80212725-80212725

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.131C>T; p.S44F; 7:80188963-80188963

 breastcarcinomaSubstitution - Missense

c.314G>A; p.R105H; 7:80199235-80199235

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.290A>G; p.D97G; 7:80189218-80189218

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1022A>G; p.D341G; 7:80217450-80217450

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1022A>G; p.D341G; 7:80217450-80217450

 large_intestine; coloncarcinomaSubstitution - Missense

c.1022A>G; p.D341G; 7:80217450-80217450

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.977C>T; p.A326V; 7:80217405-80217405

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.505C>T; p.P169S; 7:80203747-80203747

 skinmalignant_melanomaSubstitution - Missense

c.993T>A; p.N331K; 7:80217421-80217421

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.637C>A; p.H213N; 7:80211015-80211015

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.603G>T; p.V201V; 7:80210981-80210981

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.905A>G; p.Y302C; 7:80217333-80217333

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.468G>A; p.L156L; 7:80203710-80203710

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.847C>T; p.L283F; 7:80212842-80212842

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.925G>T; p.D309Y; 7:80217353-80217353

 NSNSSubstitution - Missense

c.378T>A; p.V126V; 7:80199299-80199299

 skinmalignant_melanomaSubstitution - coding silent

c.831A>G; p.K277K; 7:80212826-80212826

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - coding silent

c.264G>T; p.M88I; 7:80189192-80189192

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.576A>T; p.K192N; 7:80203818-80203818

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; plasma_cell_myelomaSubstitution - Missense

c.364G>A; p.E122K; 7:80199285-80199285

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.1054G>T; p.G352C; 7:80217482-80217482

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.851C>T; p.T284I; 7:80212846-80212846

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.111G>A; p.L37L; 7:80135271-80135271

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.111G>A; p.L37L; 7:80135271-80135271

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.232A>G; p.I78V; 7:80189160-80189160

 central_nervous_system; braingliomaSubstitution - Missense

c.983A>T; p.D328V; 7:80217411-80217411

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.271T>C; p.L91L; 7:80189199-80189199

 skinmalignant_melanomaSubstitution - coding silent

c.187G>T; p.E63*; 7:80189115-80189115

 lungcarcinoma; adenocarcinomaSubstitution - Nonsense

c.1051T>G; p.C351G; 7:80217479-80217479

 breastcarcinomaSubstitution - Missense

c.690C>T; p.Y230Y; 7:80211068-80211068

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.577G>A; p.D193N; 7:80203819-80203819

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.865G>C; p.E289Q; 7:80212860-80212860

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.865G>C; p.E289Q; 7:80212860-80212860

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense