| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 2770 |
Name | GNAI1 |
Synonym | Gi;guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1;GNAI1;guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 |
Definition | Gi1 protein alpha subunit|adenylate cyclase-inhibiting G alpha protein|guanine nucleotide-binding protein G(i) subunit alpha-1 |
Position | 7q21 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Integration of energy metabolism;Reactome;REACT:1505 |
Pathway | Signaling by GPCR;Reactome;REACT:14797 |
Pathway | signaling pathway from g-protein families;PID BioCarta;100153 |
Pathway | GABA-B receptor II signaling;PANTHER;P05731 |
Pathway | Muscarinic acetylcholine receptor 2 and 4 signaling pathway;PANTHER;P00043 |
Pathway | Toxoplasmosis;KEGG PATHWAY;hsa05145 |
Pathway | Metabotropic glutamate receptor group II pathway;PANTHER;P00040 |
Pathway | Melanogenesis;KEGG PATHWAY;hsa04916 |
Pathway | Opioid Signalling;Reactome;REACT:15295 |
Pathway | EGF receptor (ErbB1) signaling pathway;PID Curated;200085 |
Pathway | Diabetes pathways;Reactome;REACT:15380 |
Pathway | Axon guidance;KEGG PATHWAY;hsa04360 |
Pathway | aspirin blocks signaling pathway involved in platelet activation;PID BioCarta;100030 |
Pathway | Leukocyte transendothelial migration;KEGG PATHWAY;hsa04670 |
Pathway | 5HT1 type receptor mediated signaling pathway;PANTHER;P04373 |
Pathway | PI3 kinase pathway;PANTHER;P00048 |
Pathway | Endogenous cannabinoid signaling;PANTHER;P05730 |
Pathway | bioactive peptide induced signaling pathway;PID BioCarta;100226 |
Pathway | Progesterone-mediated oocyte maturation;KEGG PATHWAY;hsa04914 |
Pathway | how progesterone initiates the oocyte maturation;PID BioCarta;100104 |
Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway;PANTHER;P00026 |
Pathway | phospholipids as signalling intermediaries;PID BioCarta;100183 |
Pathway | Chagas disease;KEGG PATHWAY;hsa05142 |
Pathway | cxcr4 signaling pathway;PID BioCarta;100192 |
Pathway | Gap junction;KEGG PATHWAY;hsa04540 |
Pathway | Adenylate cyclase inhibitory pathway;PID Reactome;500840 |
Pathway | Hemostasis;Reactome;REACT:604 |
Pathway | Chemokine signaling pathway;KEGG PATHWAY;hsa04062 |
Pathway | Tight junction;KEGG PATHWAY;hsa04530 |
Pathway | Long-term depression;KEGG PATHWAY;hsa04730 |
Pathway | Gastric acid secretion;KEGG PATHWAY;hsa04971 |
Disease | Neoplasm metastasis;FunDO |
External Links | |
Links to Entrez Gene | 2770 |
Links to all GeneRIF Items | 2770 |
Links to iHOP | 2770 |
Sequence Information | |
Nucleotide Sequence | >2770 : length: 3318 GGAGGCCGAGCTCGGCTGGGCTTGGCGAGGCTGCGGCGCGGCCACCGGCGGGAGTGCAGC GGCCACTGTACCCAGAGATTCAAAACCCCAAACCCGGGACTTGGGGGCGCTGAGCCGGGC CGGGAAGCAGAGCCTGGTCGTGAGGAACAGCCGCCCGTTGCTGTCTGCCCCTTTGCGGAC AGCGTCTCCCTCGACTCCGCTTAGGAAGTGGTGGGGGCGGCGTGGCCCCCGTCGGGAGGC GTTCGAACGCCCGCTAGGAGAGAGAAAGGATTCCCCTGTGCTTGGAGCCCGCACTCGGGC GCGGAGGGAGCGGCGGCAGGCTCTCGCTTTCGGCACCATGGGCTGCACGCTGAGCGCCGA GGACAAGGCGGCGGTGGAGCGGAGTAAGATGATCGACCGCAACCTCCGTGAGGACGGCGA GAAGGCGGCGCGCGAGGTCAAGCTGCTGCTGCTCGGTGCTGGTGAATCTGGTAAAAGTAC AATTGTGAAGCAGATGAAAATTATCCATGAAGCTGGTTATTCAGAAGAGGAGTGTAAACA ATACAAAGCAGTGGTCTACAGTAACACCATCCAGTCAATTATTGCTATCATTAGGGCTAT GGGGAGGTTGAAGATAGACTTTGGTGACTCAGCCCGGGCGGATGATGCACGCCAACTCTT TGTGCTAGCTGGAGCTGCTGAAGAAGGCTTTATGACTGCAGAACTTGCTGGAGTTATAAA GAGATTGTGGAAAGATAGTGGTGTACAAGCCTGTTTCAACAGATCCCGAGAGTACCAGCT TAATGATTCTGCAGCATACTATTTGAATGACTTGGACAGAATAGCTCAACCAAATTACAT CCCGACTCAACAAGATGTTCTCAGAACTAGAGTGAAAACTACAGGAATTGTTGAAACCCA TTTTACTTTCAAAGATCTTCATTTTAAAATGTTTGATGTGGGAGGTCAGAGATCTGAGCG GAAGAAGTGGATTCATTGCTTCGAAGGAGTGACGGCGATCATCTTCTGTGTAGCACTGAG TGACTACGACCTGGTTCTAGCTGAAGATGAAGAAATGAACCGAATGCATGAAAGCATGAA ATTGTTTGACAGCATATGTAACAACAAGTGGTTTACAGATACATCCATTATACTTTTTCT AAACAAGAAGGATCTCTTTGAAGAAAAAATCAAAAAGAGCCCTCTCACTATATGCTATCC AGAATATGCAGGATCAAACACATATGAAGAGGCAGCTGCATATATTCAATGTCAGTTTGA AGACCTCAATAAAAGAAAGGACACAAAGGAAATATACACCCACTTCACATGTGCCACAGA TACTAAGAATGTGCAGTTTGTTTTTGATGCTGTAACAGATGTCATCATAAAAAATAATCT AAAAGATTGTGGTCTCTTTTAAGTTTTGCAGTTCATGGTAAAATGCATTTTCAAACCAAA TGAGTACTTATATATGGATCTCTGTAGACTAGAGTCTTGCAGCAACACAGAATGTAATAT AAGGCAAATGCATCTGGGACTTGACCAAAGTTGTTCTGTTTTGTTTTTTTAACTGAAAGT AACAGAAGGACCTTTCTTAAATGTGACAGATGGTCCTGCAGTGTGAAACTGAAGGACAGT GTTAAAGCTGGGCTCTAGTATATTGATGATTTCTGCATAAGTGTAAATATGCAAATGTAT GTATACATGTATTTATGACTTTAGTTTTCGACATTATTTTTAGGTTTTAAGAGTGGCAAC TTAGGATTTTAGGGTGATGGCTTTGGAAATAACATAAATATACCTTGTACTGAATGACAG ACTATTACTACGTTTGCCAGTTTTAAACAGCTTTATTTATGTTCATGTCCTGTAAATTTT TAAGTACAGTAATTAATATTAGGAAACATTACAGCCCTTATCTAGATTATATGTATACTT GTATTAATAAAAATGTTATTTGTACAAACATTGCACAGACTATTTTAATAACATGATTTG TTCTTTAAATTTTATGTGTTTTATTGAAATGTTCTTAAGATGAATACACCTGCCTTTGGA TCAACTATTTAAACATTGTATGCATTTTGATTTTTCCTACTTTAAGAAAATAAAATAATT TAATTTTACATTAGATTCCACGTTAGATTTGGTTTGAAAAACTAAAATTTCAGATTTCTG AGGATATACTGTCTTAGACTTATTGTACACACTTAGTTTTTATTCACTTGTTTTCACTCT GAATTTTAATATTTGGCTGATATGAATGCATTGCCTCAAAGGTGATGTCATCTTAATTTT TATTCACTTTAAATAACTACATTTTTGTTTATAACTAAGTTTGGAGGGATCCTAAGAGCA TTTTTGTGGGTAAAAAAAAAACCTGTGGACATAATGAATTTTGAGACATTGATTGGTGAG GCTTTTATTTCCCTTGAGGAGTCTCTTGTACCTAGCATACATGATAGCTCCTTGTTGGGA AGATAACAAGAAGGATCTTTGAATACTCTATTGCTGATATAATGCAAGATTTAAATTTAT ACATATAACTAATTTCAAATGTAATTATCACACTATGTTAAAATTACTTTTTTCCCTTAG ATAATTCAAATTTCTCCACTTGCTTGAGATTATATCATTTCTTTTTCAATTATACTATTA TTTCTGAGAATGAAATGGACGATTACACTTAGAAAATGAGTAATAGTGTTTAATAAGTCA GTGATTATATGTGTGCTCAAATAAGTGTTATGTATCAGCTAGATACTGAGCTTTGATAGA ATAATTTTCTTTTGATTATTCATGATGTGTCATCTCTGACCTTGTTTCAGCAAAGTAAAC AGCACTCCCCACCCCACCCTCCTTTTTTTACTCATCTTGGAAAAGGTTAGTCTTTCAGTA CACGTTGCTGGTAAGTAGTTTCCAAGTTACGTGTTGTCACTGGGTTGAAGTATATTTGTG TGTGTGTGTGTGTGTGTGTGTGTGTGTGTAACCATAAACTATATTCATATCTGTTTCATT TGGAGGATTTTCTTCTTTGTAATGTAAAGAAATTCAAAGTTATCAAAGTTCCTTAAATGT GTTAGTTTAGATTCTTTATGTGCCTTTCATGAAAGATATGTTTTCATTAATTTTACTGGT GGACCTGTAATATCCACATTGTGAAGCTGTGTATGAAATTCAACTATAATATGAATAAAT TTGAATCATGAGAATTATGGGTTAAAAAGCCACAAAGAAGCACATATTGGTGACCATCAT TAATGAAATCCTGAACTTTATTCTGTGTAATTGTGTTAATAAATCCTAATAAATTTAAAT TTTTAAAATTTTACAAAC |
Protein Sequence | >2770 : length: 354 MGCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAG YSEEECKQYKAVVYSNTIQSIIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMT AELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLDRIAQPNYIPTQQDVLRTRVK TTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEM NRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAA AYIQCQFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF |