Entrez Gene

Basic Information
Gene ID	2300
Name	FOXL1
Synonymous	forkhead box L1;FOXL1;forkhead box L1
Definition	forkhead box protein L1\|forkhead-like 11\|forkhead-related protein FKHL11\|forkhead-related transcription factor 7
Position	16q24
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.842T>C; p.L281P; 16:86579565-86579565	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Missense
c.151C>T; p.P51S; 16:86578874-86578874	skin	malignant_melanoma	Substitution - Missense
c.79G>A; p.G27S; 16:86578802-86578802	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.79G>A; p.G27S; 16:86578802-86578802	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.79G>A; p.G27S; 16:86578802-86578802	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.193G>A; p.A65T; 16:86578916-86578916	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.193G>A; p.A65T; 16:86578916-86578916	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1029C>A; p.H343Q; 16:86579752-86579752	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.166G>A; p.A56T; 16:86578889-86578889	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.10C>A; p.L4I; 16:86578733-86578733	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.141G>A; p.P47P; 16:86578864-86578864	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.84C>G; p.L28L; 16:86578807-86578807	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.44C>T; p.S15L; 16:86578767-86578767	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.416G>T; p.R139L; 16:86579139-86579139	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.183G>A; p.A61A; 16:86578906-86578906	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.183G>A; p.A61A; 16:86578906-86578906	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.323T>C; p.V108A; 16:86579046-86579046	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.359G>A; p.G120D; 16:86579082-86579082	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.79G>T; p.G27C; 16:86578802-86578802	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.819G>T; p.Q273H; 16:86579542-86579542	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.655G>T; p.G219C; 16:86579378-86579378	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.52C>A; p.L18M; 16:86578775-86578775	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.605C>A; p.P202Q; 16:86579328-86579328	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.804G>A; p.A268A; 16:86579527-86579527	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.804G>A; p.A268A; 16:86579527-86579527	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.804G>A; p.A268A; 16:86579527-86579527	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.814G>A; p.G272S; 16:86579537-86579537	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.331C>T; p.P111S; 16:86579054-86579054	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.440C>G; p.P147R; 16:86579163-86579163	prostate	carcinoma	Substitution - Missense
c.888G>A; p.S296S; 16:86579611-86579611	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.165C>A; p.I55I; 16:86578888-86578888	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.212C>G; p.T71R; 16:86578935-86578935	liver	carcinoma	Substitution - Missense
c.96C>T; p.F32F; 16:86578819-86578819	skin	malignant_melanoma	Substitution - coding silent
c.96C>T; p.F32F; 16:86578819-86578819	breast	carcinoma	Substitution - coding silent
c.128G>T; p.R43L; 16:86578851-86578851	skin; shoulder	malignant_melanoma	Substitution - Missense
c.350C>T; p.P117L; 16:86579073-86579073	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.350C>T; p.P117L; 16:86579073-86579073	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1022T>A; p.V341E; 16:86579745-86579745	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1022T>A; p.V341E; 16:86579745-86579745	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.267C>A; p.N89K; 16:86578990-86578990	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.267C>A; p.N89K; 16:86578990-86578990	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.267C>A; p.N89K; 16:86578990-86578990	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.929C>T; p.A310V; 16:86579652-86579652	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.267C>A; p.N89K; 16:86578990-86578990	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.267C>A; p.N89K; 16:86578990-86578990	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.627delG; p.T211fs*53; 16:86579350-86579350	oesophagus	carcinoma; adenocarcinoma	Deletion - Frameshift
c.98C>T; p.A33V; 16:86578821-86578821	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.959G>A; p.G320D; 16:86579682-86579682	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.320T>C; p.F107S; 16:86579043-86579043	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.503C>G; p.A168G; 16:86579226-86579226	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.287G>C; p.S96T; 16:86579010-86579010	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.323T>A; p.V108D; 16:86579046-86579046	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.323T>A; p.V108D; 16:86579046-86579046	urinary_tract; bladder	carcinoma	Substitution - Missense
c.60G>A; p.L20L; 16:86578783-86578783	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.45G>A; p.S15S; 16:86578768-86578768	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.45G>A; p.S15S; 16:86578768-86578768	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1012C>T; p.P338S; 16:86579735-86579735	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.106G>T; p.A36S; 16:86578829-86578829	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.174C>T; p.I58I; 16:86578897-86578897	skin	malignant_melanoma	Substitution - coding silent
c.902delC; p.S302fs*11; 16:86579625-86579625	large_intestine; rectum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.895G>A; p.A299T; 16:86579618-86579618	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.895G>A; p.A299T; 16:86579618-86579618	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.313G>A; p.D105N; 16:86579036-86579036	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.262G>A; p.D88N; 16:86578985-86578985	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.270G>A; p.R90R; 16:86578993-86578993	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.195G>A; p.A65A; 16:86578918-86578918	prostate	carcinoma	Substitution - coding silent
c.168G>A; p.A56A; 16:86578891-86578891	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.726C>A; p.S242S; 16:86579449-86579449	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.907A>T; p.S303C; 16:86579630-86579630	skin	malignant_melanoma	Substitution - Missense
c.791A>G; p.D264G; 16:86579514-86579514	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.277T>C; p.W93R; 16:86579000-86579000	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.121T>G; p.S41A; 16:86578844-86578844	pancreas	carcinoma; acinar_carcinoma	Substitution - Missense
c.282G>T; p.Q94H; 16:86579005-86579005	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.104C>T; p.A35V; 16:86578827-86578827	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.16G>A; p.D6N; 16:86578739-86578739	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.16G>A; p.D6N; 16:86578739-86578739	skin	malignant_melanoma	Substitution - Missense
c.806G>A; p.G269E; 16:86579529-86579529	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.218A>G; p.N73S; 16:86578941-86578941	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.337G>A; p.E113K; 16:86579060-86579060	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense

COSMIC somatic mutation [Top]