Entrez Gene

Basic Information
Gene ID	2155
Name	F7
Synonymous	coagulation factor VII (serum prothrombin conversion accelerator);F7;coagulation factor VII (serum prothrombin conversion accelerator)
Definition	FVII coagulation protein\|coagulation factor VII\|eptacog alfa\|proconvertin
Position	13q34
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC somatic mutation [Top]
c.1098G>A; p.M366I; 13:113118705-113118705	skin	malignant_melanoma	Substitution - Missense
c.357C>T; p.G119G; 13:113113887-113113887	bone; extraskeletal	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.1006G>A; p.V336M; 13:113118613-113118613	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.780C>T; p.N260N; 13:113117571-113117571	breast	carcinoma	Substitution - coding silent
c.515G>T; p.C172F; 13:113115744-113115744	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.316+3G>A; p.?; 13:113113779-113113779	liver	carcinoma	Unknown
c.24C>T; p.L8L; 13:113105865-113105865	skin	malignant_melanoma	Substitution - coding silent
c.858G>A; p.A286A; 13:113118465-113118465	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.694G>A; p.V232M; 13:113117485-113117485	skin	malignant_melanoma	Substitution - Missense
c.752C>A; p.A251E; 13:113117543-113117543	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.428C>T; p.T143M; 13:113113958-113113958	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.428C>T; p.T143M; 13:113113958-113113958	thyroid	carcinoma	Substitution - Missense
c.668delA; p.E223fs*10; 13:113116862-113116862	skin; mucosal	malignant_melanoma	Deletion - Frameshift
c.1239G>A; p.R413R; 13:113118846-113118846	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1168G>A; p.A390T; 13:113118775-113118775	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.996G>A; p.T332T; 13:113118603-113118603	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.872C>G; p.P291R; 13:113118479-113118479	skin	malignant_melanoma	Substitution - Missense
c.753G>A; p.A251A; 13:113117544-113117544	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.910G>A; p.A304T; 13:113118517-113118517	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.792G>A; p.L264L; 13:113117583-113117583	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.704C>A; p.A235D; 13:113117495-113117495	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.430C>T; p.H144Y; 13:113113960-113113960	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2T>C; p.M1T; 13:113105843-113105843	liver	carcinoma	Substitution - Missense
c.439G>A; p.D147N; 13:113115668-113115668	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.566C>A; p.P189H; 13:113115795-113115795	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.682-1G>A; p.?; 13:113117472-113117472	skin	malignant_melanoma	Unknown
c.453T>A; p.C151*; 13:113115682-113115682	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Nonsense
c.1027G>A; p.G343S; 13:113118634-113118634	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.525C>T; p.H175H; 13:113115754-113115754	breast	carcinoma	Substitution - coding silent
c.470G>T; p.G157V; 13:113115699-113115699	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.796G>A; p.A266T; 13:113117587-113117587	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.796G>A; p.A266T; 13:113117587-113117587	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.116C>G; p.P39R; 13:113106896-113106896	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1100C>G; p.T367S; 13:113118707-113118707	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.1129G>A; p.V377M; 13:113118736-113118736	skin	malignant_melanoma	Substitution - Missense
c.1090C>T; p.R364W; 13:113118697-113118697	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1090C>T; p.R364W; 13:113118697-113118697	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1066G>A; p.E356K; 13:113118673-113118673	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.308C>A; p.S103Y; 13:113113768-113113768	breast	carcinoma	Substitution - Missense
c.620G>T; p.S207I; 13:113116814-113116814	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.550G>C; p.G184R; 13:113115779-113115779	lung; left_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.994A>T; p.T332S; 13:113118601-113118601	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1080C>A; p.L360L; 13:113118687-113118687	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.621C>T; p.S207S; 13:113116815-113116815	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1080C>A; p.L360L; 13:113118687-113118687	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.715_716insG; p.T241fs*40; 13:113117506-113117507	stomach	adenocarcinoma	Insertion - Frameshift
c.15C>T; p.A5A; 13:113105856-113105856	liver	carcinoma	Substitution - coding silent
c.414C>T; p.G138G; 13:113113944-113113944	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.15C>T; p.A5A; 13:113105856-113105856	liver	carcinoma	Substitution - coding silent
c.751G>A; p.A251T; 13:113117542-113117542	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.580C>T; p.P194S; 13:113116774-113116774	skin	malignant_melanoma	Substitution - Missense
c.829G>A; p.D277N; 13:113118436-113118436	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.851G>T; p.R284L; 13:113118458-113118458	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.829G>A; p.D277N; 13:113118436-113118436	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1385G>C; p.R462P; 13:113118992-113118992	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.526G>A; p.E176K; 13:113115755-113115755	skin	malignant_melanoma	Substitution - Missense
c.1005C>T; p.F335F; 13:113118612-113118612	skin	malignant_melanoma	Substitution - coding silent
c.1206G>A; p.G402G; 13:113118813-113118813	skin	malignant_melanoma	Substitution - coding silent
c.509_510ins132; p.R170_S171ins23; 13:113115738-113115739	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; functioning	Insertion - In frame
c.467G>A; p.G156D; 13:113115696-113115696	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.797C>T; p.A266V; 13:113117588-113117588	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.797C>T; p.A266V; 13:113117588-113117588	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.88G>A; p.G30R; 13:113106868-113106868	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.752C>T; p.A251V; 13:113117543-113117543	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.752C>T; p.A251V; 13:113117543-113117543	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.752C>T; p.A251V; 13:113117543-113117543	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.665G>A; p.G222E; 13:113116859-113116859	skin	malignant_melanoma	Substitution - Missense
c.700G>A; p.G234R; 13:113117491-113117491	skin	malignant_melanoma	Substitution - Missense
c.459C>T; p.N153N; 13:113115688-113115688	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.765C>T; p.F255F; 13:113117556-113117556	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.205C>T; p.R69W; 13:113110764-113110764	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1371A>G; p.P457P; 13:113118978-113118978	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1367G>A; p.R456H; 13:113118974-113118974	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Missense
c.1187G>T; p.S396I; 13:113118794-113118794	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.319G>A; p.G107R; 13:113113849-113113849	NS	malignant_melanoma	Substitution - Missense
c.319G>A; p.G107R; 13:113113849-113113849	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; hairy_cell_leukaemia	Substitution - Missense
c.319G>A; p.G107R; 13:113113849-113113849	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; hairy_cell_leukaemia	Substitution - Missense
c.997C>A; p.L333M; 13:113118604-113118604	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.160G>A; p.V54I; 13:113110719-113110719	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.912G>A; p.A304A; 13:113118519-113118519	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.878C>T; p.T293M; 13:113118485-113118485	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.72C>T; p.V24V; 13:113106852-113106852	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.300C>A; p.F100L; 13:113113760-113113760	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.508C>T; p.R170C; 13:113115737-113115737	central_nervous_system; brain	glioma	Substitution - Missense
c.973G>A; p.E325K; 13:113118580-113118580	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.973G>A; p.E325K; 13:113118580-113118580	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.973G>A; p.E325K; 13:113118580-113118580	breast	carcinoma	Substitution - Missense
c.1251C>A; p.Y417*; 13:113118858-113118858	ovary	carcinoma; serous_carcinoma	Substitution - Nonsense
c.317-1G>A; p.?; 13:113113846-113113846	skin	malignant_melanoma	Unknown
c.984C>A; p.F328L; 13:113118591-113118591	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.642delG; p.G216fs*17; 13:113116836-113116836	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.588A>G; p.G196G; 13:113116782-113116782	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1263C>A; p.I421I; 13:113118870-113118870	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1237C>T; p.R413W; 13:113118844-113118844	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.817C>T; p.L273F; 13:113118424-113118424	skin	malignant_melanoma	Substitution - Missense
c.981G>A; p.T327T; 13:113118588-113118588	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1222C>T; p.H408Y; 13:113118829-113118829	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.750C>T; p.S250S; 13:113117541-113117541	prostate	carcinoma	Substitution - coding silent
c.729C>T; p.I243I; 13:113117520-113117520	breast	carcinoma	Substitution - coding silent
c.387C>T; p.I129I; 13:113113917-113113917	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.387C>T; p.I129I; 13:113113917-113113917	lung; middle_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.408C>T; p.F136F; 13:113113938-113113938	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.998T>A; p.L333Q; 13:113118605-113118605	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.795C>T; p.I265I; 13:113117586-113117586	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.550G>A; p.G184R; 13:113115779-113115779	skin	malignant_melanoma	Substitution - Missense
c.1178C>T; p.S393L; 13:113118785-113118785	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1178C>T; p.S393L; 13:113118785-113118785	skin	malignant_melanoma	Substitution - Missense
c.1178C>T; p.S393L; 13:113118785-113118785	skin	malignant_melanoma	Substitution - Missense

COSMIC somatic mutation [Top]