| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 2155 |
Name | F7 |
Synonym | SPCA;coagulation factor VII (serum prothrombin conversion accelerator);F7;coagulation factor VII (serum prothrombin conversion accelerator) |
Definition | FVII coagulation protein|coagulation factor VII|eptacog alfa|proconvertin |
Position | 13q34 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Gamma-carboxylation, transport, and amino-terminal cleavage of proteins;PID Reactome;500540 |
Pathway | Hemostasis;Reactome;REACT:604 |
Pathway | Gamma-carboxylation of protein precursors;PID Reactome;500541 |
Pathway | Removal of aminoterminal propeptides from gamma-carboxylated proteins;PID Reactome;500543 |
Pathway | Metabolism of proteins;Reactome;REACT:17015 |
Pathway | extrinsic prothrombin activation pathway;PID BioCarta;100168 |
Pathway | Complement and coagulation cascades;KEGG PATHWAY;hsa04610 |
Pathway | Blood coagulation;PANTHER;P00011 |
Pathway | Angiogenesis;PANTHER;P00005 |
Pathway | Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus;PID Reactome;500542 |
Pathway | Extrinsic Pathway;PID Reactome;500301 |
Disease | HEMATOLOGICAL;GAD |
Disease | Cardiovascular disease;FunDO |
Disease | obesity;GAD |
Disease | Breast cancer;FunDO |
Disease | Neoplasm metastasis;FunDO |
Disease | cardiac death myocardial infarct;GAD |
Disease | stroke, ischemic;GAD |
Disease | atherosclerosis, coronary;GAD |
Disease | Systemic infection;FunDO |
Disease | METABOLIC;GAD |
Disease | Low plasma levels of factor VIIc;GAD |
Disease | factor VII levels;GAD |
Disease | heart disease, ischemic;GAD |
Disease | Coronary Artery Disease;GAD |
Disease | CARDIOVASCULAR;GAD |
Disease | Rabies;FunDO |
Disease | Hemorrhagic disorder;FunDO |
Disease | Factor VII;GAD |
Disease | plasma factor VII activity and antigen levels;GAD |
Disease | blood pressure, arterial;GAD |
Disease | Hyperlipidemia;FunDO |
Disease | cerebral infarct;GAD |
Disease | Factor VII deficiency;OMIM |
Disease | myocardial infarct;GAD |
Disease | Myocardial infarction, decreased susceptibility to;OMIM |
External Links | |
Links to Entrez Gene | 2155 |
Links to all GeneRIF Items | 2155 |
Links to iHOP | 2155 |
Sequence Information | |
Nucleotide Sequence | >2155 : length: 3166 GTTTGAGGCCCCCAACCTCCCTTGGGTTCAGTAATTCACTAGAAGGACTCATAGAATCCA CTGAAGTGGATACACTCACAGGTACCGTTTATTACAGCAAAGGATGCAGGCTTAAGTCTG CAGAGGGACCAGGCACAAGCTTCCCCTTGTCCTCTCCCTGTGGGGTCATGTGGACAGTCC TTAATTCTCCCAGAATGACGTGTGACGAGACGTGGGAAGTACTGCCAACTTGGGAAGCTC TACGAGCCCCGGTGTCCAGAGGTTTTATCAGGGCTCAATCACATAGACCCAGCTGACCAC CCGCATGGCTGACCTCAGTCTCAGCCCCTCCAGAGGCTACGCCGATAGTGCGGCCCAAGG CCCCACCATACATCACATTGTCAGCTAGACCATCCAGCATGGCTCAAGGCCCAGAAGAGA GCCCAGCAAGCTGGAGGAGGCTGAAGAGAGAGGCTTCCTGCTGGTCATCTGGGTCCAGAA TGCCTGGAGATCTCTGCTCAGCCCTGGTGCCCAGCAGCCCTGACAAGGATGACCAGCTGA TCTGTGTGAACGAGAACGGCGGCTGTGAGCAGTACTGCAGTGACCACACGGGCACCAAGC GCTCCTGTCGGTGCCACGAGGGGTACTCTCTGCTGGCAGACGGGGTGTCCTGCACACCCA CAGTTGAATATCCATGTGGAAAAATACCTATTCTAGAAAAAAGAAATGCCAGCAAACCCC AAGGCCGAATTGTGGGGGGCAAGGTGTGCCCCAAAGGGGAGTGTCCATGGCAGGTCCTGT TGTTGGTGAATGGAGCTCAGTTGTGTGGGGGGACCCTGATCAACACCATCTGGGTGGTCT CCGCGGCCCACTGTTTCGACAAAATCAAGAACTGGAGGAACCTGATCGCGGTGCTGGGCG AGCACGACCTCAGCGAGCACGACGGGGATGAGCAGAGCCGGCGGGTGGCGCAGGTCATCA TCCCCAGCACGTACGTCCCGGGCACCACCAACCACGACATCGCGCTGCTCCGCCTGCACC AGCCCGTGGTCCTCACTGACCATGTGGTGCCCCTCTGCCTGCCCGAACGGACGTTCTCTG AGAGGACGCTGGCCTTCGTGCGCTTCTCATTGGTCAGCGGCTGGGGCCAGCTGCTGGACC GTGGCGCCACGGCCCTGGAGCTCATGGTCCTCAACGTGCCCCGGCTGATGACCCAGGACT GCCTGCAGCAGTCACGGAAGGTGGGAGACTCCCCAAATATCACGGAGTACATGTTCTGTG CCGGCTACTCGGATGGCAGCAAGGACTCCTGCAAGGGGGACAGTGGAGGCCCACATGCCA CCCACTACCGGGGCACGTGGTACCTGACGGGCATCGTCAGCTGGGGCCAGGGCTGCGCAA CCGTGGGCCACTTTGGGGTGTACACCAGGGTCTCCCAGTACATCGAGTGGCTGCAAAAGC TCATGCGCTCAGAGCCACGCCCAGGAGTCCTCCTGCGAGCCCCATTTCCCTAGCCCAGCA GCCCTGGCCTGTGGAGAGAAAGCCAAGGCTGCGTCGAACTGTCCTGGCACCAAATCCCAT ATATTCTTCTGCAGTTAATGGGGTAGAGGAGGGCATGGGAGGGAGGGAGAGGTGGGGAGG GAGACAGAGACAGAAACAGAGAGAGACAGAGACAGAGAGAGACTGAGGGAGAGACTCTGA GGACATGGAGAGAGACTCAAAGAGACTCCAAGATTCAAAGAGACTAATAGAGACACAGAG ATGGAATAGAAAAGATGAGAGGCAGAGGCAGACAGGCGCTGGACAGAGGGGCAGGGGAGT GCCAAGGTTGTCCTGGAGGCAGACAGCCCAGCTGAGCCTCCTTACCTCCCTTCAGCCAAG CCCACCTGCACGTGATCTGCTGGCCTCAGGCTGCTGCTCTGCCTTCATTGCTGGAGACAG TAGAGGCATGAACACACATGGATGCACACACACACACGCCAATGCACACACACAGAGATA TGCACACACACGGATGCACACACAGATGGTCACACAGAGATACGCAAACACACCGATGCA CACGCACATAGAGATATGCACACACAGATGCACACACAGATATACACATGGATGCACGCA CATGCCAATGCACGCACACATCAGTGCACACGGATGCACAGAGATATGCACACACCGATG TGCGCACACACAGATATGCACACACATGGATGAGCACACACACACCAATGCGCACACACA CCGATGTACACACACAGATGCACACACAGATGCACACACACCGATGCTGACTCCATGTGT GCTGTCCTCTGAAGGCGGTTGTTTAGCTCTCACTTTTCTGGTTCTTATCCATTATCATCT TCACTTCAGACAATTCAGAAGCATCACCATGCATGGTGGCGAATGCCCCCAAACTCTCCC CCAAATGTATTTCTCCCTTCGCTGGGTGCCGGGCTGCACAGACTATTCCCCACCTGCTTC CCAGCTTCACAATAAACGGCTGCGTCTCCTCCGCACACCTGTGGTGCCTGCCACCCACTG GGTTGCCCATGATTCATTTTTGGAGCCCCCGGTGCTCATCCTCTGAGATGCTCTTTTCTT TCACAATTTTCAACATCACTGAAATGAACCCTCACATGGAAGCTATTTTTTAAAAACAAA AGCTGTTTGATAGATGTTTGAGGCTGTAGCTCCCAGGATCCTGTGGAATTGGATGTTCTC TCCCTGCCACAGCCCTTGTCAATGATATTTCACAGAGACCCTGGGAGCACCTGCTCAAGA GTCAGGGACACACGCATCACTAAATGCAAGTTCCCAGGCCCTGGCTGCAGTGGGAGGACC TGGCAAGCTGCACTCTTGCTGAGTCCCCAGGGTGGTGGAAGAAGAATGAGAAACACATGA ACAGAGAAATGGGGAGGTGACAAACAGTGCCCCCACTCAGACTCCGGCAAGCACGGCTCA GAGAGTGGACTCGATGCCATCCCTGCAGGGCCGTCCTGGGCACCACTGGCACTCACAGCA GCAAGGTGGGCACCATTGGCACTCACAGCAGCAAGGCAGGCACCAGCAACCCACCTCGGG GGCACTCAGGCATCATCTACTTCAGAGCAGACAGGGTCTATGAACTACAGCCGTGGGCTG CTTCCAAGGCACCCTGCTCTTGTAAATAAAGTTTTATGGGAACACA |
Protein Sequence | >2155 : length: 480 MVSQALRLLCLLLGLQGCLAAVFVTQEEAHGVLHRRRRANAFLEELRPGSLERECKEEQC SFEEAREIFKDAERTKLFWISYSDGDQCASSPCQNGGSCKDQLQSYICFCLPAFEGRNCE TQESPASWRRLKREASCWSSGSRMPGDLCSALVPSSPDKDDQLICVNENGGCEQYCSDHT GTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILEKRNASKPQGRIVGGKVCPKGECPW QVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVLGEHDLSEHDGDEQSRRVA QVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQ LLDRGATALELMVLNVPRLMTQDCLQQSRKVGDSPNITEYMFCAGYSDGSKDSCKGDSGG PHATHYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIEWLQKLMRSEPRPGVLLRAPFP |