| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 993 |
Name | CDC25A |
Synonymous | cell division cycle 25A;CDC25A;cell division cycle 25A |
Definition | CDC25 isoform A1-CAG|CDC25A2-CAG isoform|M-phase inducer phosphatase 1|dual specificity phosphatase CDC25A |
Position | 3p21 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
interacts with |
AR | HPRD; |
interacts with |
BTRC | BIOGRID; |
interacts with |
BTRC | MINT; |
interacts with |
CCNA1 | BIOGRID; |
interacts with |
CCNB1 | BIOGRID; |
interacts with |
CCNB1 | HPRD; |
interacts with |
CCNE1 | BIOGRID; |
interacts with |
CCNE1 | HPRD; |
interacts with |
CDK2 | BIOGRID; |
interacts with |
CDK2 | HPRD; |
interacts with |
CDKN3 | HPRD; |
interacts with |
CHEK1 | BIOGRID; |
interacts with |
CHEK1 | HPRD; |
interacts with |
CHEK2 | BIOGRID; |
interacts with |
CHEK2 | HPRD; |
interacts with |
CHEK2 | MINT; |
interacts with |
CUL1 | BIOGRID; |
interacts with |
CUX1 | HPRD; |
interacts with |
EGFR | BIOGRID; |
interacts with |
EGFR | HPRD; |
interacts with |
FBXW11 | BIOGRID; |
interacts with |
FBXW11 | HPRD; |
interacts with |
FBXW11 | MINT; |
interacts with |
HRAS | HPRD; |
interacts with |
MAP3K5 | BIOGRID; |
interacts with |
MAP3K5 | HPRD; |
interacts with |
MAPK14 | BIOGRID; |
interacts with |
NAA10 | BIOGRID; |
interacts with |
NAA10 | HPRD; |
interacts with |
PIM1 | BIOGRID; |
interacts with |
PIM1 | HPRD; |
interacts with |
RAF1 | BIOGRID; |
interacts with |
RAF1 | HPRD; |
interacts with |
ROCK1 | BIOGRID; |
interacts with |
ROCK1 | CELL_MAP; |
interacts with |
ROCK1 | HPRD; |
interacts with |
YWHAB | BIOGRID; |
interacts with |
YWHAB | HPRD; |
interacts with |
YWHAB | MINT; |
interacts with |
YWHAE | BIOGRID; |
interacts with |
YWHAE | HPRD; |
interacts with |
YWHAE | MINT; |
interacts with |
YWHAQ | MINT; |
interacts with |
YWHAZ | BIOGRID; |
interacts with |
YWHAZ | HPRD; |
interacts with |
YWHAZ | MINT; |
Metabolic Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
metabolic catalysis |
E2F1 | NCI_NATURE; |
metabolic catalysis |
E2F4 | NCI_NATURE; |
metabolic catalysis |
LIN37 | REACTOME; |
metabolic catalysis |
LIN52 | REACTOME; |
metabolic catalysis |
LIN54 | REACTOME; |
metabolic catalysis |
LIN9 | REACTOME; |
metabolic catalysis |
MAX | NCI_NATURE; |
metabolic catalysis |
MYC | NCI_NATURE; |
metabolic catalysis |
MYC | REACTOME; |
metabolic catalysis |
RBBP4 | REACTOME; |
metabolic catalysis |
RBL2 | REACTOME; |
metabolic catalysis |
TFDP2 | NCI_NATURE; |
sequential catalysis |
CDC25A | HUMANCYC; |
Signaling Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
reacts with |
CDC25A | REACTOME; |
reacts with |
CDC6 | REACTOME; |
reacts with |
CDK1 | REACTOME; |
reacts with |
E2F1 | REACTOME; |
reacts with |
PCNA | REACTOME; |
reacts with |
RBL1 | REACTOME; |
reacts with |
TOP2A | REACTOME; |
state change |
CHEK1 | NCI_NATURE; |
state change |
CHEK1 | REACTOME; |
state change |
CHEK2 | NCI_NATURE; |
state change |
Rock1 | CELL_MAP; |