| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 993 |
Name | CDC25A |
Synonym | CDC25A2;cell division cycle 25A;CDC25A;cell division cycle 25A |
Definition | CDC25 isoform A1-CAG|CDC25A2-CAG isoform|M-phase inducer phosphatase 1|dual specificity phosphatase CDC25A |
Position | 3p21 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | E2F transcription factor network;PID Curated;200027 |
Pathway | Activation of ATR in response to replication stress;PID Reactome;500319 |
Pathway | cyclins and cell cycle regulation;PID BioCarta;100207 |
Pathway | p53-Independent DNA Damage Response;PID Reactome;500994 |
Pathway | Progesterone-mediated oocyte maturation;KEGG PATHWAY;hsa04914 |
Pathway | Cell Cycle Checkpoints;Reactome;REACT:1538 |
Pathway | Ubiquitin Mediated Degradation of Phosphorylated Cdc25A;PID Reactome;500938 |
Pathway | Cyclin A:Cdk2-associated events at S phase entry;PID Reactome;500375 |
Pathway | Cell Cycle, Mitotic;Reactome;REACT:152 |
Pathway | cell cycle: g1/s check point;PID BioCarta;100160 |
Pathway | Cell cycle;KEGG PATHWAY;hsa04110 |
Pathway | Validated targets of C-MYC transcriptional activation;PID Curated;200045 |
Pathway | Cyclin E associated events during G1/S transition;PID Reactome;500877 |
Disease | altered cell-cycle;GAD |
External Links | |
Links to Entrez Gene | 993 |
Links to all GeneRIF Items | 993 |
Links to iHOP | 993 |
Sequence Information | |
Nucleotide Sequence | >993 : length: 3899 CTGCTGGGAGTTTTCATTGACCTCTGCTCCCCCTCTCATTTTGATCCCCGCTCTTCTGCT CTGGGCTCCGCCCCCTTCTGAGAGCCGATGACCTGGCAGAGTCCCGCGAGCCGCTTTCTT CTTCCCCTCTCATTGGCCCAGCCTAGCTGCCATTCGGTTGAGAGGAGGAGAAGTTGCTTA CTGATTGGTGGATTCCGTTTGGCGCCAACTAGGAAAGGGGGGCGGGGCAGCAGCTGGCCC CACTGAGCCGCTATTACCGCGAAAGGCCGGCCTGGCTGCGACAGCCTGGGTTGCCGGCGC CCGCCCGCCCGCTGGCCTCGCGGTGTGAGAGGGAAGCACCCGTGCCTGTGGCTGGTGGCT GGCGCCTGGAGGGTCCGCACACCCGCCCGGCCGCGCCGCTTGCCCGCGGCAGCCGCGTCC CTGAACCGCGGAGTCGTGTTTGTGTTTGACCCGCGGGCGCCGGTGGCGCGCGGCCGAGGC CGGTGTCGGCGGGGCGGGGCGGTCGCGGCGGAGGCAGAGGAAGAGGGAGCGGGAGCTCTG CGAGGCCGGGCGCCGCCATGGAACTGGGCCCGGAGCCCCCGCACCGCCGCCGCCTGCTCT TCGCCTGCAGCCCCCCTCCCGCGTCGCAGCCCGTCGTGAAGGCGCTATTTGGCGCTTCAG CCGCCGGGGGACTGTCGCCTGTCACCAACCTGACCGTCACTATGGACCAGCTGCAGGGTC TGGGCAGTGATTATGAGCAACCACTGGAGGTGAAGAACAACAGTAATCTGCAGAGAATGG GCTCCTCCGAGTCAACAGATTCAGGTTTCTGTCTAGATTCTCCTGGGCCATTGGACAGTA AAGAAAACCTTGAAAATCCTATGAGAAGAATACATTCCCTACCTCAGAAGCTGTTGGGAT GTAGTCCAGCTCTGAAGAGGAGCCATTCTGATTCTCTTGACCATGACATCTTTCAGCTCA TCGACCCAGATGAGAACAAGGAAAATGAAGCCTTTGAGTTTAAGAAGCCAGTAAGACCTG TATCTCGTGGCTGCCTGCACTCTCATGGACTCCAGGAGGGTAAAGATCTCTTCACACAGA GGCAGAACTCTGCCCCAGCTCGGATGCTTTCCTCAAATGAAAGAGATAGCAGTGAACCAG GGAATTTCATTCCTCTTTTTACACCCCAGTCACCTGTGACAGCCACTTTGTCTGATGAGG ATGATGGCTTCGTGGACCTTCTCGATGGAGAGAATCTGAAGAATGAGGAGGAGACCCCCT CGTGCATGGCAAGCCTCTGGACAGCTCCTCTCGTCATGAGAACTACAAACCTTGACAACC GATGCAAGCTGTTTGACTCCCCTTCCCTGTGTAGCTCCAGCACTCGGTCAGTGTTGAAGA GACCAGAACGATCTCAAGAGGAGTCTCCACCTGGAAGTACAAAGAGGAGGAAGAGCATGT CTGGGGCCAGCCCCAAAGAGTCAACTAATCCAGAGAAGGCCCATGAGACTCTTCATCAGT CTTTATCCCTGGCATCTTCCCCCAAAGGAACCATTGAGAACATTTTGGACAATGACCCAA GGGACCTTATAGGAGACTTCTCCAAGGGTTATCTCTTTCATACAGTTGCTGGGAAACATC AGGATTTAAAATACATCTCTCCAGAAATTATGGCATCTGTTTTGAATGGCAAGTTTGCCA ACCTCATTAAAGAGTTTGTTATCATCGACTGTCGATACCCATATGAATACGAGGGAGGCC ACATCAAGGGTGCAGTGAACTTGCACATGGAAGAAGAGGTTGAAGACTTCTTATTGAAGA AGCCCATTGTACCTACTGATGGCAAGCGTGTCATTGTTGTGTTTCACTGCGAGTTTTCTT CTGAGAGAGGTCCCCGCATGTGCCGGTATGTGAGAGAGAGAGATCGCCTGGGTAATGAAT ACCCCAAACTCCACTACCCTGAGCTGTATGTCCTGAAGGGGGGATACAAGGAGTTCTTTA TGAAATGCCAGTCTTACTGTGAGCCCCCTAGCTACCGGCCCATGCACCACGAGGACTTTA AAGAAGACCTGAAGAAGTTCCGCACCAAGAGCCGGACCTGGGCAGGGGAGAAGAGCAAGA GGGAGATGTACAGTCGTCTGAAGAAGCTCTGAGGGCGGCAGGACCAGCCAGCAGCAGCCC AAGCTTCCCTCCATCCCCCTTTACCCTCTTTGCTGCAGAGAAACTTAAGCAAAGGGGACA GCTGTGTGACATTTGGAGAGGGGGCCTGGGACTTCCATGCCTTAAACCTACCTCCCACAC TCCCAAGGTTGGAGCCCAGGGCATCTTGCTGGCTACGCCTCTTCTGTCCCTGTTAGACGT CCTCCGTCCATATCAGAACTGTGCCACAATGCAGTTCTGAGCACCGTGTCAAGCTGCTCT GAGCCACAGTGGGATGAACCAGCCGGGGCCTTATCGGGCTCCAGCCATCTCATGAGGGGA GAGGAGACGGAGGGGAGTAGAGAAGTTACACAGAAATGCTGCTGGCCAAATAGCAAAGAC AACCTGGGAAGGAAAGGTCTTTGTGGGATAATCCATATGTTTAATTTATTCAACTTCATC AATCACTTTATTTTATTTTTTTTTCTAACTCCTGGAGACTTATTTTACTGCTTCATTAGG TTGAAATACTGCCATTCTAGGTAGGGTTTTATTATCCCAGGGACTACCTCGGCTTTTAAT TTAAAAAAAAAAAAGAAGTGGGTAAGAAAATGCAAACCTGTTATAAGTTATCGGACAGAA AGCTAGGTGCTCTGTCACCCCCAGGAGGCGCTGTGGTACTGGGGCTGCTGCTATTTAAGC CAAGAACTGAGGTCCTGGTGAGAGCGTTGGACCCAGGCTTGGCTGCCTGACATAAGCTAA ATCTCCCAGACCCACCACTGGCTACCGATATCTATTTGGTGGGAGGTGTGGCCCTGTTCT TCCTCACCCCAGTTCCATGACATTGGCTGGTATAGGAGCCACAGTCAGGAAAGCACTTGA GGCAGCATCTGTTGGGCCACCCCCGGCTCAGTGCTGGAATGTTGCAGTGTAGGTTTCCCA GGGAAGGGGGGTGGGGGTAGGTGGGCTCCACAGGATGGGGGAGGAGCATGTCCACTGAGT ATCTTCCTTATGTTGCTGTGATATTGATAGCTTTTATTTTCTAATTTTTAAAAAATGGTC ATATTATGAGTCAAAGAGTATCAAATCAGTGTTGGATGGACCACCCAAGGGTGAGGAGAG GGGCTGGAAGCCCTGGGCATTAGGAGAAGGGAGTGGGTGCTGGCATGGACATGACTGGAT AGAATTTTCTCAGGAGGGAGCTTGGTGGATTTTGAAGGTAAAACTTTCTGGGTTTATCAT GTTTTAATTTTAGAGACAGGGAGTGATGAATCATCACCGGTTGTCCCCTTATCTAACTCC ATAAAAGTGGGAATTTCAAAAGAACACCTCATCCAAGGAGCTGGGGCAGACTTCATTGAT TCTAGAGAGACCTGTTTCAGTGCCTACTCATCCCTGCCCTCTGGTGCCAGCCTCCTTACC ATCACGGCTTCACTGAGGTGTAGGTGGGTTTTTCTTAAACAGGAGACAGTCTCTCCCCTC TTACCTCAACTTCTTGGGGTGGGAATCAGTGATACTGGAGATGGCTAGTTGCTGTGTTAC GGGTTTGAGTTACATTTGGCTATAAAACAATCTTGTTGGGAAAAATGTGGGGGAGAGGAC TTCTTCCTACACGCGCATTGAGACAGATTCCAACTGGTTAATGATATTGTTTGTAAGAAA GAGATTCTGTTGGTTGACTGCCTAAAGAGAAAGGTGGGATGGCCTTCAGATTATACCAGC TTAGCTAGCATTACTAACCAACTGTTGGAAGCTCTGAAAATAAAAGATCTTGAACCCAT |
Protein Sequence | >993 : length: 524 MELGPEPPHRRRLLFACSPPPASQPVVKALFGASAAGGLSPVTNLTVTMDQLQGLGSDYE QPLEVKNNSNLQRMGSSESTDSGFCLDSPGPLDSKENLENPMRRIHSLPQKLLGCSPALK RSHSDSLDHDIFQLIDPDENKENEAFEFKKPVRPVSRGCLHSHGLQEGKDLFTQRQNSAP ARMLSSNERDSSEPGNFIPLFTPQSPVTATLSDEDDGFVDLLDGENLKNEEETPSCMASL WTAPLVMRTTNLDNRCKLFDSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGASPK ESTNPEKAHETLHQSLSLASSPKGTIENILDNDPRDLIGDFSKGYLFHTVAGKHQDLKYI SPEIMASVLNGKFANLIKEFVIIDCRYPYEYEGGHIKGAVNLHMEEEVEDFLLKKPIVPT DGKRVIVVFHCEFSSERGPRMCRYVRERDRLGNEYPKLHYPELYVLKGGYKEFFMKCQSY CEPPSYRPMHHEDFKEDLKKFRTKSRTWAGEKSKREMYSRLKKL |