| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 8837 |
Name | CFLAR |
Synonymous | CASP8 and FADD-like apoptosis regulator;CFLAR;CASP8 and FADD-like apoptosis regulator |
Definition | FADD-like antiapoptotic molecule 1|MACH-related inducer of toxicity|caspase homolog|caspase-eight-related protein|caspase-like apoptosis regulatory protein|caspase-related inducer of apoptosis|cellular FLICE-like inhibitory protein|inhibitor of FLICE|usur |
Position | 2q33-q34 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
in same component |
CASP8 | IMID; |
in same component |
CASP8 | NCI_NATURE; |
in same component |
FADD | NCI_NATURE; |
in same component |
FAS | NCI_NATURE; |
in same component |
FASLG | NCI_NATURE; |
interacts with |
BCL2L1 | BIOGRID; |
interacts with |
BCL2L1 | HPRD; |
interacts with |
CASP10 | BIOGRID; |
interacts with |
CASP10 | HPRD; |
interacts with |
CASP3 | BIOGRID; |
interacts with |
CASP3 | CELL_MAP; |
interacts with |
CASP3 | HPRD; |
interacts with |
CASP6 | HPRD; |
interacts with |
CASP7 | HPRD; |
interacts with |
CASP8 | BIOGRID; |
interacts with |
CASP8 | HPRD; |
interacts with |
DAXX | HPRD; |
interacts with |
DEDD2 | BIOGRID; |
interacts with |
DEDD2 | HPRD; |
interacts with |
DEDD | BIOGRID; |
interacts with |
DEDD | HPRD; |
interacts with |
DOK2 | BIOGRID; |
interacts with |
FADD | BIOGRID; |
interacts with |
FADD | CELL_MAP; |
interacts with |
FADD | HPRD; |
interacts with |
FAS | BIOGRID; |
interacts with |
IKBKB | HPRD; |
interacts with |
ITCH | BIOGRID; |
interacts with |
MAP2K1 | HPRD; |
interacts with |
MAP2K4 | HPRD; |
interacts with |
MAP2K7 | HPRD; |
interacts with |
MAP3K14 | BIOGRID; |
interacts with |
NFKB1 | CELL_MAP; |
interacts with |
NFKB1 | HPRD; |
interacts with |
NOD1 | BIOGRID; |
interacts with |
PSEN2 | HPRD; |
interacts with |
RAF1 | BIOGRID; |
interacts with |
RAF1 | HPRD; |
interacts with |
RIPK1 | BIOGRID; |
interacts with |
RIPK1 | HPRD; |
interacts with |
RIPK2 | BIOGRID; |
interacts with |
RIPK2 | HPRD; |
interacts with |
SF3B3 | BIOGRID; |
interacts with |
TNFRSF10A | BIOGRID; |
interacts with |
TNFRSF10A | HPRD; |
interacts with |
TNFRSF10B | BIOGRID; |
interacts with |
TNFRSF10B | HPRD; |
interacts with |
TP53 | BIOGRID; |
interacts with |
TRAF1 | BIOGRID; |
interacts with |
TRAF1 | CELL_MAP; |
interacts with |
TRAF1 | HPRD; |
interacts with |
TRAF2 | BIOGRID; |
interacts with |
TRAF2 | CELL_MAP; |
interacts with |
TRAF2 | HPRD; |
interacts with |
TRAF3 | BIOGRID; |
Metabolic Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
metabolic catalysis |
MAX | NCI_NATURE; |
metabolic catalysis |
MYC | NCI_NATURE; |
Signaling Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
reacts with |
CASP10 | NCI_NATURE; |
reacts with |
CASP8 | IMID; |
reacts with |
CASP8 | NCI_NATURE; |
reacts with |
CFLAR | IMID; |
reacts with |
CFLAR | NCI_NATURE; |
reacts with |
FADD | NCI_NATURE; |
reacts with |
FAS | NCI_NATURE; |
reacts with |
FASLG | NCI_NATURE; |