| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 7010 |
Name | TEK |
Synonymous | TEK tyrosine kinase, endothelial;TEK;TEK tyrosine kinase, endothelial |
Definition | angiopoietin-1 receptor|endothelial tyrosine kinase|tunica interna endothelial cell kinase|tyrosine kinase with Ig and EGF homology domains-2|tyrosine-protein kinase receptor TEK|tyrosine-protein kinase receptor TIE-2 |
Position | 9p21 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
in same component |
ANGPT1 | NCI_NATURE; |
in same component |
ANGPT1 | REACTOME; |
in same component |
ANGPT2 | NCI_NATURE; |
in same component |
ANGPT2 | REACTOME; |
in same component |
ANGPT4 | REACTOME; |
in same component |
DOK2 | REACTOME; |
in same component |
GRB14 | NCI_NATURE; |
in same component |
GRB14 | REACTOME; |
in same component |
GRB7 | NCI_NATURE; |
in same component |
GRB7 | REACTOME; |
in same component |
ITGA5 | NCI_NATURE; |
in same component |
ITGB1 | NCI_NATURE; |
in same component |
PTPN11 | NCI_NATURE; |
in same component |
PTPN11 | REACTOME; |
in same component |
SHC1 | NCI_NATURE; |
in same component |
SHC1 | REACTOME; |
in same component |
SOS1 | REACTOME; |
in same component |
TNIP2 | NCI_NATURE; |
interacts with |
ANGPT1 | BIOGRID; |
interacts with |
ANGPT2 | BIOGRID; |
interacts with |
ANGPT4 | BIOGRID; |
interacts with |
DOK2 | BIOGRID; |
interacts with |
IKBKG | BIOGRID; |
interacts with |
SHC1 | MINT; |
interacts with |
TIE1 | BIOGRID; |
Metabolic Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
metabolic catalysis |
ELF1 | NCI_NATURE; |
metabolic catalysis |
ELF2 | NCI_NATURE; |
Signaling Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
reacts with |
ANGPT1 | NCI_NATURE; |
reacts with |
ANGPT1 | REACTOME; |
reacts with |
ANGPT2 | NCI_NATURE; |
reacts with |
ANGPT2 | REACTOME; |
reacts with |
ANGPT4 | REACTOME; |
reacts with |
DOK2 | REACTOME; |
reacts with |
GRB14 | NCI_NATURE; |
reacts with |
GRB14 | REACTOME; |
reacts with |
GRB7 | NCI_NATURE; |
reacts with |
GRB7 | REACTOME; |
reacts with |
ITGA5 | NCI_NATURE; |
reacts with |
ITGB1 | NCI_NATURE; |
reacts with |
PTPN11 | NCI_NATURE; |
reacts with |
PTPN11 | REACTOME; |
reacts with |
SHC1 | NCI_NATURE; |
reacts with |
SHC1 | REACTOME; |
reacts with |
SOS1 | REACTOME; |
reacts with |
TEK | NCI_NATURE; |
reacts with |
TEK | REACTOME; |
reacts with |
TNIP2 | NCI_NATURE; |
state change |
ANGPT1 | REACTOME; |
state change |
FN1 | NCI_NATURE; |
state change |
TEK | REACTOME; |