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Cancer metastasis database
General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction

Basic Information

Gene ID

351

Name

APP

Synonymous

amyloid beta (A4) precursor protein;APP;amyloid beta (A4) precursor protein

Definition

alzheimer disease amyloid protein|amyloid beta A4 protein|beta-amyloid peptide|beta-amyloid peptide(1-40)|beta-amyloid peptide(1-42)|cerebral vascular amyloid peptide|peptidase nexin-II|preA4|protease nexin-II

Position

21q21.3

Gene Type

protein-coding

Gene Interactions:

Physical Interaction
Metabolic Interaction
Signaling Interaction

Physical Interaction   [Top]

Interaction Type

Interactor

Data Source

in same component

 GPC1NCI_NATURE;

in same component

 NGFRNCI_NATURE;

interacts with

 Abl1MINT;

interacts with

 ABL1MINT;

interacts with

 ACHEBIOGRID;

interacts with

 APBA1BIOGRID;

interacts with

 APBA2BIOGRID;

interacts with

 APBA3BIOGRID;

interacts with

 Apbb1BIOGRID;

interacts with

 APBB1BIOGRID;

interacts with

 Apbb1MINT;

interacts with

 APBB2BIOGRID;

interacts with

 APBB3BIOGRID;

interacts with

 APPBP2BIOGRID;

interacts with

 BGNBIOGRID;

interacts with

 BLMHBIOGRID;

interacts with

 CALRBIOGRID;

interacts with

 CAV1BIOGRID;

interacts with

 CLSTN1BIOGRID;

interacts with

 COL25A1BIOGRID;

interacts with

 CTSDMINT;

interacts with

 DAB1BIOGRID;

interacts with

 DAB2BIOGRID;

interacts with

 DLG4MINT;

interacts with

 FBLN1BIOGRID;

interacts with

 Grb2BIOGRID;

interacts with

 GSNBIOGRID;

interacts with

 HGSBIOGRID;

interacts with

 HSD17B10BIOGRID;

interacts with

 HSP90AA1BIOGRID;

interacts with

 HSPA4BIOGRID;

interacts with

 HSPD1BIOGRID;

interacts with

 KLC1BIOGRID;

interacts with

 MAPK8IP1MINT;

interacts with

 NAE1BIOGRID;

interacts with

 NCSTNBIOGRID;

interacts with

 NumbCELL_MAP;

interacts with

 NumblCELL_MAP;

interacts with

 PARK2BIOGRID;

interacts with

 SETBIOGRID;

interacts with

 Shc1BIOGRID;

interacts with

 SHC1BIOGRID;

interacts with

 SHC1MINT;

interacts with

 SNCABIOGRID;

interacts with

 SNCBBIOGRID;

interacts with

 STUB1BIOGRID;

interacts with

 TtrMINT;

Metabolic Interaction   [Top]

There is no record for APP

Signaling Interaction   [Top]

Interaction Type

Interactor

Data Source

reacts with

 APPNCI_NATURE;

reacts with

 GPC1NCI_NATURE;

reacts with

 NGFRNCI_NATURE;

state change

 APH1ACELL_MAP;

state change

 APH1BCELL_MAP;

state change

 NCSTNCELL_MAP;

state change

 PSEN1CELL_MAP;

state change

 PSEN2CELL_MAP;

state change

 PSENENCELL_MAP;