| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 331 |
Name | XIAP |
Synonymous | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase;XIAP;X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase |
Definition | E3 ubiquitin-protein ligase XIAP|IAP-like protein|X-linked IAP|baculoviral IAP repeat-containing protein 4|inhibitor of apoptosis protein 3 |
Position | Xq25 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
in same component |
BMPR2 | NCI_NATURE; |
in same component |
CASP3 | IMID; |
in same component |
CASP3 | REACTOME; |
in same component |
CASP7 | IMID; |
in same component |
CASP7 | REACTOME; |
in same component |
CASP9 | IMID; |
in same component |
CASP9 | REACTOME; |
in same component |
DIABLO | IMID; |
in same component |
DIABLO | REACTOME; |
in same component |
MAP3K7 | NCI_NATURE; |
interacts with |
ACVRL1 | HPRD; |
interacts with |
AIFM1 | BIOGRID; |
interacts with |
AKT1 | BIOGRID; |
interacts with |
AKT1 | HPRD; |
interacts with |
AKT2 | BIOGRID; |
interacts with |
AKT2 | HPRD; |
interacts with |
APAF1 | HPRD; |
interacts with |
BCL10 | BIOGRID; |
interacts with |
BIRC2 | BIOGRID; |
interacts with |
BIRC5 | BIOGRID; |
interacts with |
BIRC5 | HPRD; |
interacts with |
BMPR1B | BIOGRID; |
interacts with |
BMPR2 | BIOGRID; |
interacts with |
CASP3 | BIOGRID; |
interacts with |
CASP3 | HPRD; |
interacts with |
CASP3 | MINT; |
interacts with |
CASP4 | BIOGRID; |
interacts with |
CASP7 | BIOGRID; |
interacts with |
CASP7 | HPRD; |
interacts with |
CASP7 | MINT; |
interacts with |
CASP9 | BIOGRID; |
interacts with |
CASP9 | HPRD; |
interacts with |
CASP9 | MINT; |
interacts with |
CHEK1 | BIOGRID; |
interacts with |
CHEK1 | HPRD; |
interacts with |
COMMD1 | BIOGRID; |
interacts with |
COMMD1 | HPRD; |
interacts with |
DIABLO | BIOGRID; |
interacts with |
DIABLO | HPRD; |
interacts with |
DIABLO | INTACT; |
interacts with |
DIABLO | MINT; |
interacts with |
DYNLL2 | BIOGRID; |
interacts with |
DYNLL2 | HPRD; |
interacts with |
EXTL3 | BIOGRID; |
interacts with |
GSPT1 | BIOGRID; |
interacts with |
HAX1 | BIOGRID; |
interacts with |
HTRA2 | BIOGRID; |
interacts with |
HTRA2 | HPRD; |
interacts with |
MAGED1 | BIOGRID; |
interacts with |
MAGED1 | HPRD; |
interacts with |
MAGED1 | MINT; |
interacts with |
MAP3K2 | BIOGRID; |
interacts with |
MAP3K7 | BIOGRID; |
interacts with |
MAP3K7 | HPRD; |
interacts with |
Ngfrap1 | BIOGRID; |
interacts with |
NOTCH1 | HPRD; |
interacts with |
NOTCH1 | MINT; |
interacts with |
RAF1 | BIOGRID; |
interacts with |
SERTAD1 | BIOGRID; |
interacts with |
SIAH1 | INTACT; |
interacts with |
STRADB | BIOGRID; |
interacts with |
STRADB | HPRD; |
interacts with |
STUB1 | BIOGRID; |
interacts with |
TAB1 | BIOGRID; |
interacts with |
TAB2 | BIOGRID; |
interacts with |
TAB2 | HPRD; |
interacts with |
TRAF2 | BIOGRID; |
interacts with |
TRAF6 | BIOGRID; |
interacts with |
TRAF6 | HPRD; |
interacts with |
UBE2D1 | BIOGRID; |
interacts with |
UBE2D1 | MINT; |
interacts with |
UBE2D2 | BIOGRID; |
interacts with |
UBE2D3 | BIOGRID; |
interacts with |
UBE2D4 | BIOGRID; |
interacts with |
UBE2E2 | BIOGRID; |
interacts with |
UBE2J2 | BIOGRID; |
interacts with |
UBE2L3 | BIOGRID; |
interacts with |
UBE2N | BIOGRID; |
interacts with |
UBE2V1 | BIOGRID; |
interacts with |
UBE2V2 | BIOGRID; |
interacts with |
UBE2W | BIOGRID; |
interacts with |
USP11 | BIOGRID; |
interacts with |
WDYHV1 | BIOGRID; |
interacts with |
WDYHV1 | HPRD; |
interacts with |
XAF1 | BIOGRID; |
interacts with |
XAF1 | HPRD; |
Metabolic Interaction [Top] | ||
There is no record for XIAP | ||
Signaling Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
reacts with |
BMPR2 | NCI_NATURE; |
reacts with |
CASP3 | IMID; |
reacts with |
CASP3 | REACTOME; |
reacts with |
CASP7 | IMID; |
reacts with |
CASP7 | REACTOME; |
reacts with |
CASP9 | IMID; |
reacts with |
CASP9 | REACTOME; |
reacts with |
DIABLO | IMID; |
reacts with |
DIABLO | REACTOME; |
reacts with |
MAP3K7 | NCI_NATURE; |
reacts with |
XIAP | IMID; |
reacts with |
XIAP | NCI_NATURE; |
reacts with |
XIAP | REACTOME; |
state change |
SMAD7 | NCI_NATURE; |
state change |
STRAP | NCI_NATURE; |
state change |
TGFBR1 | NCI_NATURE; |
state change |
TGFBR2 | NCI_NATURE; |