| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 331 |
Name | XIAP |
Synonym | API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3;X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase;XIAP;X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase |
Definition | E3 ubiquitin-protein ligase XIAP|IAP-like protein|X-linked IAP|baculoviral IAP repeat-containing protein 4|inhibitor of apoptosis protein 3 |
Position | Xq25 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Apoptosis;Reactome;REACT:578 |
Pathway | TGF-beta receptor signaling;PID Curated;200195 |
Pathway | BMP receptor signaling;PID Curated;200123 |
Pathway | Focal adhesion;KEGG PATHWAY;hsa04510 |
Pathway | Pathways in cancer;KEGG PATHWAY;hsa05200 |
Pathway | NOD-like receptor signaling pathway;KEGG PATHWAY;hsa04621 |
Pathway | Apoptosis;KEGG PATHWAY;hsa04210 |
Pathway | Ubiquitin mediated proteolysis;KEGG PATHWAY;hsa04120 |
Pathway | SMAC binds to IAPs;PID Reactome;500884 |
Pathway | SMAC-mediated dissociation of IAP:caspase complexes;PID Reactome;500934 |
Pathway | Apoptosis signaling pathway;PANTHER;P00006 |
Pathway | Small cell lung cancer;KEGG PATHWAY;hsa05222 |
Pathway | Caspase cascade in apoptosis;PID Curated;200148 |
Pathway | Toxoplasmosis;KEGG PATHWAY;hsa05145 |
Disease | Lymphoproliferative syndrome, X-linked, 2;OMIM |
Disease | Ischemia;FunDO |
Disease | Other well-defined immunodeficiency syndromes;KEGG DISEASE;H00107 |
Disease | Immune system diseases;KEGG DISEASE |
Disease | Copper metabolism disorder;FunDO |
Disease | Multiple sclerosis;FunDO |
Disease | Cancer;FunDO |
Disease | Familial Mediterranean Fever;GAD |
Disease | mevalonate kinase deficiency;GAD |
Disease | Primary immunodeficiency;KEGG DISEASE |
Disease | Immunologic deficiency syndrome;FunDO |
Disease | Cryopyrin-associated Periodic Syndromes;GAD |
External Links | |
Links to Entrez Gene | 331 |
Links to all GeneRIF Items | 331 |
Links to iHOP | 331 |
Sequence Information | |
Nucleotide Sequence | >331 : length: 8524 ATCCGGTTCGGGGAGGTGGCGGGACCTTGGCGGCGCCCGGAGCCGGCGTGGCGCTCATCG AGGGACGCCCGGCCCAAGTGGCTGGGGCCAAGCCGCAGAGCGGAGTTGGCATTTCCAGAT TGGGGCTCGGGCCGCGCCTCCTCCGGGACCCTCCCCTTGGACCGAGCCGATCGCCGCGGG GCAGTTCGGGCCGGCTGTCCTGGCGCGAAAAGGTGGACAAGTCCTATTTTCAAGAGAAGA TGACTTTTAACAGTTTTGAAGGATCTAAAACTTGTGTACCTGCAGACATCAATAAGGAAG AAGAATTTGTAGAAGAGTTTAATAGATTAAAAACTTTTGCTAATTTTCCAAGTGGTAGTC CTGTTTCAGCATCAACACTGGCACGAGCAGGGTTTCTTTATACTGGTGAAGGAGATACCG TGCGGTGCTTTAGTTGTCATGCAGCTGTAGATAGATGGCAATATGGAGACTCAGCAGTTG GAAGACACAGGAAAGTATCCCCAAATTGCAGATTTATCAACGGCTTTTATCTTGAAAATA GTGCCACGCAGTCTACAAATTCTGGTATCCAGAATGGTCAGTACAAAGTTGAAAACTATC TGGGAAGCAGAGATCATTTTGCCTTAGACAGGCCATCTGAGACACATGCAGACTATCTTT TGAGAACTGGGCAGGTTGTAGATATATCAGACACCATATACCCGAGGAACCCTGCCATGT ATAGTGAAGAAGCTAGATTAAAGTCCTTTCAGAACTGGCCAGACTATGCTCACCTAACCC CAAGAGAGTTAGCAAGTGCTGGACTCTACTACACAGGTATTGGTGACCAAGTGCAGTGCT TTTGTTGTGGTGGAAAACTGAAAAATTGGGAACCTTGTGATCGTGCCTGGTCAGAACACA GGCGACACTTTCCTAATTGCTTCTTTGTTTTGGGCCGGAATCTTAATATTCGAAGTGAAT CTGATGCTGTGAGTTCTGATAGGAATTTCCCAAATTCAACAAATCTTCCAAGAAATCCAT CCATGGCAGATTATGAAGCACGGATCTTTACTTTTGGGACATGGATATACTCAGTTAACA AGGAGCAGCTTGCAAGAGCTGGATTTTATGCTTTAGGTGAAGGTGATAAAGTAAAGTGCT TTCACTGTGGAGGAGGGCTAACTGATTGGAAGCCCAGTGAAGACCCTTGGGAACAACATG CTAAATGGTATCCAGGGTGCAAATATCTGTTAGAACAGAAGGGACAAGAATATATAAACA ATATTCATTTAACTCATTCACTTGAGGAGTGTCTGGTAAGAACTACTGAGAAAACACCAT CACTAACTAGAAGAATTGATGATACCATCTTCCAAAATCCTATGGTACAAGAAGCTATAC GAATGGGGTTCAGTTTCAAGGACATTAAGAAAATAATGGAGGAAAAAATTCAGATATCTG GGAGCAACTATAAATCACTTGAGGTTCTGGTTGCAGATCTAGTGAATGCTCAGAAAGACA GTATGCAAGATGAGTCAAGTCAGACTTCATTACAGAAAGAGATTAGTACTGAAGAGCAGC TAAGGCGCCTGCAAGAGGAGAAGCTTTGCAAAATCTGTATGGATAGAAATATTGCTATCG TTTTTGTTCCTTGTGGACATCTAGTCACTTGTAAACAATGTGCTGAAGCAGTTGACAAGT GTCCCATGTGCTACACAGTCATTACTTTCAAGCAAAAAATTTTTATGTCTTAATCTAACT CTATAGTAGGCATGTTATGTTGTTCTTATTACCCTGATTGAATGTGTGATGTGAACTGAC TTTAAGTAATCAGGATTGAATTCCATTAGCATTTGCTACCAAGTAGGAAAAAAAATGTAC ATGGCAGTGTTTTAGTTGGCAATATAATCTTTGAATTTCTTGATTTTTCAGGGTATTAGC TGTATTATCCATTTTTTTTACTGTTATTTAATTGAAACCATAGACTAAGAATAAGAAGCA TCATACTATAACTGAACACAATGTGTATTCATAGTATACTGATTTAATTTCTAAGTGTAA GTGAATTAATCATCTGGATTTTTTATTCTTTTCAGATAGGCTTAACAAATGGAGCTTTCT GTATATAAATGTGGAGATTAGAGTTAATCTCCCCAATCACATAATTTGTTTTGTGTGAAA AAGGAATAAATTGTTCCATGCTGGTGGAAAGATAGAGATTGTTTTTAGAGGTTGGTTGTT GTGTTTTAGGATTCTGTCCATTTTCTTTTAAAGTTATAAACACGTACTTGTGCGAATTAT TTTTTTAAAGTGATTTGCCATTTTTGAAAGCGTATTTAATGATAGAATACTATCGAGCCA ACATGTACTGACATGGAAAGATGTCAAAGATATGTTAAGTGTAAAATGCAAGTGGCAAAA CACTATGTATAGTCTGAGCCAGATCAAAGTATGTATGTTTTTAATATGCATAGAACAAAA GATTTGGAAAGATATACACCAAACTGTTAAATGTGGTTTCTCTTCGGGGAGGGGGGGATT GGGGGAGGGGCCCCAGAGGGGTTTTATAGGGGCCTTTTCACTTTCTACTTTTTTCATTTT GTTCTGTTCGAATTTTTTATAAGTATGTATTACTTTTGTAATCAGAATTTTTAGAAAGTA TTTTGCTGATTTAAAGGCTTAGGCATGTTCAAACGCCTGCAAAACTACTTATCACTCAGC TTTAGTTTTTCTAATCCAAGAAGGCAGGGCAGTTAACCTTTTTGGTGCCAATGTGAAATG TAAATGATTTTATGTTTTTCCTGCTTTGTGGATGAAAAATATTTCTGAGTGGTAGTTTTT TGACAGGTAGACCATGTCTTATCTTGTTTCAAAATAAGTATTTCTGATTTTGTAAAATGA AATATAAAATATGTCTCAGATCTTCCAATTAATTAGTAAGGATTCATCCTTAATCCTTGC TAGTTTAAGCCTGCCTAAGTCACTTTACTAAAAGATCTTTGTTAACTCAGTATTTTAAAC ATCTGTCAGCTTATGTAGGTAAAAGTAGAAGCATGTTTGTACACTGCTTGTAGTTATAGT GACAGCTTTCCATGTTGAGATTCTCATATCATCTTGTATCTTAAAGTTTCATGTGAGTTT TTACCGTTAGGATGATTAAGATGTATATAGGACAAAATGTTAAGTCTTTCCTCTACCTAC ATTTGTTTTCTTGGCTAGTAATAGTAGTAGATACTTCTGAAATAAATGTTCTCTCAAGAT CCTTAAAACCTCTTGGAAATTATAAAAATATTGGCAAGAAAAGAAGAATAGTTGTTTAAA TATTTTTTAAAAAACACTTGAATAAGAATCAGTAGGGTATAAACTAGAAGTTTAAAAATG CTTCATAGAACGTCCAGGGTTTACATTACAAGATTCTCACAACAAACCTATTGTAGAGGT GAGTAAGGCATGTTACTACAGAGGAAAGTTTGAGAGTAAAACTGTAAAAAATTATATTTT TGTTGTACTTTCTAAGAGAAAGAGTATTGTTATGTTCTCCTAACTTCTGTTGATTACTAC TTTAAGTGATATTCATTTAAAACATTGCAAATTTATTTTATTTATTTAATTTTCTTTTTG AGATGGAGTCTTGCTTGTCACCCAGGCTGGAGTGCAGTGGAGTGATCTCTGCTCACTGCA ACCTCCGCCTTCTGGGTTCAAGCGATTCTCGTGCCTCAGCTTCCTGAGTAGCTGGAATTA CAGGCAGGTGCCACCATGCCCGACTAATTTTTTTTTATTTTTAGTAGAGACGGGGTTTCA CCATGTTGGCCAGGCTGGTATCAAACTCCTGACCTCAAGAGATCCACTCGCCTTGCCCTC CCAAAGTGCTGGGATTACAGGCTTGAGCCACCACGCCCGGCTAAAACATTGCAAATTTAA ATGAGAGTTTTAAAAATTAAATAATGACTGCCCTGTTTCTGTTTTAGTATGTAAATCCTC AGTTCTTCACCTTTGCACTGTCTGCCACTTAGTTTGGTTATATAGTCATTAACTTGAATT TGGTCTGTATAGTCTAGACTTTAAATTTAAAGTTTTCTACAAGGGGAGAAAAGTGTTAAA ATTTTTAAAATATGTTTTCCAGGACACTTCACTTCCAAGTCAGGTAGGTAGTTCAATCTA GTTGTTAGCCAAGGACTCAAGGACTGAATTGTTTTAACATAAGGCTTTTCCTGTTCTGGG AGCCGCACTTCATTAAAATTCTTCTAAAACTTGTATGTTTAGAGTTAAGCAAGACTTTTT TTCTTCCTCTCCATGAGTTGTGAAATTTAATGCACAACGCTGATGTGGCTAACAAGTTTA TTTTAAGAATTGTTTAGAAATGCTGTTGCTTCAGGTTCTTAAAATCACTCAGCACTCCAA CTTCTAATCAAATTTTTGGAGACTTAACAGCATTTGTCTGTGTTTGAACTATAAAAAGCA CCGGATCTTTTCCATCTAATTCCGCAAAAATTGATCATTTGCAAAGTCAAAACTATAGCC ATATCCAAATCTTTTCCCCCTCCCAAGAGTTCTCAGTGTCTACATGTAGACTATTCCTTT TCTGTATAAAGTTCACTCTAGGATTTCAAGTCACCACTTATTTTACATTTTAGTCATGCA AAGATTCAAGTAGTTTTGCAATAAGTACTTATCTTTATTTGTAATAATTTAGTCTGCTGA TCAAAAGCATTGTCTTAATTTTTGAGAACTGGTTTTAGCATTTACAAACTAAATTCCAGT TAATTAATTAATAGCTTTATATTGCCTTTCCTGCTACATTTGGTTTTTTCCCCTGTCCCT TTGATTACGGGCTAAGGTAGGGTAGAGTGGGTGTAGTGAGTGTATATAATGTGATTTGGC CCTGTGTATTATGATATTTTGTTATTTTTGTTGTTATATTATTTACATTTCAGTAGTTGT TTTTTGTGTTTCCATTTTAGTGGATAAAATTTGTATTTTGAACTATGAATGGAGACTACC GCCCCAGCATTAGTTTCACATGATATACCCTTTAAACCCGAATCATTGTTTTATTTCCTG ATTACACAGGTGTTGAATGGGGAAAGGGGCTAGTATATCAGTAGGATATACTATGGGATG TATATATATCATTGCTGTTAGAGAAATGAAATAAAATGGGGCTGGGCTCAGTGGCTCACG CCTGTAATCCCAGCACTTTGGGAGGCTGAGGCAGGTGGATCACGAGGTCAGGAGATCGAG ACCATCCTGGCTAACACGGTGAAACCCCGTCTCTACTAAAAAACAGAAAATTAGCCGGGC GTGGTGGCGGGCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGTGTGA ACCCGGGAGGCAGAGCTTGCAGTGAGCCGAGATCTCGCCACTGCACTCCAGCCTGGGCAA CAGAGCAAGACTCTGTCTCAAAAAAAAAAAAAAAAGAAATAAGAAAATGGGAAGCAATAT TTGACATAGTTCTTTTTAGTCAAATCTACTTGTTAAAAAAAGGGTAGCAGTTTATTCATC TGTGAAAGGAAAATAATACTTATCTTACAAGGTTGCAAGAGCTCAAGGAGACCATGTATG TAAAGTTCCTGCTGTAAATATGAACTCCCATCCTAATACCCTTTTACCTCTCTGTGGGTT TGTCTTGACCTGGAAATTTGGGCTAAAACTTAGAAAAAATTCTTACATGATAACTCAGTG ATGCTTACTCATAGTTTTTGGTGTTTCTCATAGATAAGATATAAATCAGCTGGGCGCGGT GGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCAGATCACCTGAGGTCG GGAGGTCGAGACCAGCCTGACCAACATGGAGAAACCCCGTCTCTACTAAAAATACAAAAT TAGCTGGGCGTGGTGGCTCATGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGA ATCGCTTGAACCCAGGAGGCGGAGGTTGTGGTGAGCGAAGATCGTGCCATTGCACTCCAG CCTGGGCAACAAGAGCAAAACTCTGTCTCAAAAAAAAAAAAAGATATAAATCACAATAAA TAAATAGGTCAATACAAATGTTAGCCAGGCGTGGTGGCACATGCCCATAGTCGCAGCTAC TCTGGAGGCAGAGGCAGGAGGATCACTTGAGCCCATGAATTTGAGGCAGCAGTGAGCTAT GATTGTGCCACTGTACTCCAGTCTGGGTGACAGAGTGAGACCCCATCTCTAAATAAATAG GTCAAACCCTTAAAAATATTTAAATTCTTAAAAAATTGAAAAGATTATTCTTCTCAAATT TAGTTGAGCTTTCTAAGAGAAGCAATTGGCTTTTTCCCACTTCAATAATCATTTTCAGTT TGACTCATACAGTTAACACAATGTGAATTTCTTCCTCAGCATAACAGAGTTATAGAATGA CAGGGCTGGAAGTGACCTTAGAGAGTATCCAGTTCTTTCATTTTACAGGTGAGGCAACTG AGACTCAAAGGTGATGTAATTTGTGCAAAGATTATAGCTAATTAGTAGCAGAGCCCTGAC TGGGACATAGTTTGAAGGTGAAAAACTTCACCAAGCTACCTTTCTTGAAAGGTCCAAATG TTTATGTTTTCAACTACTCTTTCCACTGTACCATAACTTTCACTACATATTAAATGACAC TTTATAACTAATATAATAGGACAATCATCAATGCATATATAGCCAGCCCTTCATATCTGT GGGTTTTGCATCCATGGATTCAACCAAGGAGGAATTGAAAACACTGAGAAAAAAAAAAAA GACCACACAATAAAAAAAAAAAATACAAAATAATACAAAGAAAAAGCCAAAATTGTCATA CTGTTGTTAAGCAACAGTATAACAACTATTTACATAGCATTAAGGTTGGTGCAAAAATGC AAAAAAAAAAAAAGCAATTATTTTTAAACCAACCTAATATATTGTATTAGGTATTAAAGT CATCTGGACATGAATTAAAGTATATGATGCCAGCCTGGACAAAAGGCAAAACCCTGTCTC TACAAAAAATACAAAAATTAGCTGGGCATGGTGGTGTGTGCCTGTAGTCCTGGCTACTCC GGAGCCTGAGGTGGGAGGATCGCTTGAGTCTGGGAGGCAGAGGCTGCATTGAGCTATGAT CATGGCACTGCATTCCAGCCTGGGTGACAGTGCAAGACCTTGTCTCAGAATAAATAAAGT ATGTGATGAAGATGTGCATACATTATATGCAAATACTGTTTTTTTTTTTTTTAATTTAAA CAGTCTCACTGTGTTGCCCAGGATGGAGTGCAATGGCACAATCTTGGCTCATGGCAAACT CTGCCTCGCAAGCAGCTGGGACTACAGGCATGCTCCACGGTGCCCAGTTAATTTTTTTTG TATTCTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGGCTAGTCTTGAATTTCTGACCT CAAGTGATTCATCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCACGGCCGGCTAAT TTTTGTATTTTTTAGTAGTGACTGGTTTCGCGGTGTTGACCAGGCTGGTCTCGAACTCCT GATCTCAGGTGATCTGCCTGCCTCGGCCTCACAAAGTGCTGGGATTACAGGTGTGAACCA CTGCTCCCGGCCTTGTGTGATTTTATCTAAGGGACTTAAGCGTCCTCAGGTCCTAGGGGG TCGTGAAACCAAAACCCCAGGGATAGCAAGGGACAATTGTATCTTCAAAGTAGACAAATG GCGCCGGGCACGGTGGCTCACGCCTGTAATCCCAGCAGTTTCCGAGGCTGAGGCAGGCGG CTCACCTGAGGTCAGGAGTTGGAGACCAGCCTGGCCAACATGCTGAAACCCTGTCTGTAC AAAAATACAAAAATAGCTGGGCATGGTGGCGCATGCCTGTAGTCCCAGCTACTAGAGCGA CTGAGGCAGGAGAATTGCTTGAACCTGGGAGGCGGAGGTTGCAGGGAGCCAAGATGGCGC CACCGCACTCCAGCCTAGGTGATAGAGTGAGACTCCCTCTCAAAAACAAAACAAAACAAA AAAATTAGACAAATGCTACATTAATGTTTGGGTGGTCAGATTCTACTTTGAATCTGAAGT TTGCAGATATGCCTATAGATTTTTGGAGTTTACCACTTTCTTATTCTGTATCATTAATGT AATATTTTAAATTACTATATATGTTACCATTTTTCTGGATTTAGTAAGAAATTTGCAGTT TTGGTTTGATGTAACAAGGGTTTTAATGTAATTTATGTTAGATTTTGCATTTTTTTCATT ACTGTTATATTTTAACCTGACTGACTGATCTAATTGTATTAGTATTGTGAATAATCATGT GAAATGTTTTGAGACAGAGTACTATATTTGTGAATATAATTTTATGGTTTTTTTCACTTA GAACCTTTCTGTGTGGAAAACTAAGAAAATTGCTTTCTGCTGTATAATCTGGCATTCATT GTAGATTAAAGCTTATTTTTCTGTGAATAAAACGTATTCAATAAAATACTATTCTTTAAA ATTA |
Protein Sequence | >331 : length: 497 MTFNSFEGSKTCVPADINKEEEFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDT VRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENY LGSRDHFALDRPSETHADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLT PRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSE SDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKC FHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTTEKTP SLTRRIDDTIFQNPMVQEAIRMGFSFKDIKKIMEEKIQISGSNYKSLEVLVADLVNAQKD SMQDESSQTSLQKEISTEEQLRRLQEEKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDK CPMCYTVITFKQKIFMS |