| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 3002 |
Name | GZMB |
Synonymous | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1);GZMB;granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) |
Definition | C11|CTLA-1|T-cell serine protease 1-3E|cathepsin G-like 1|cytotoxic T-lymphocyte proteinase 2|cytotoxic serine protease B|fragmentin 2|fragmentin-2|granzyme B|human lymphocyte protein |
Position | 14q11.2 |
Gene Type | protein-coding |
Gene Interactions: | Physical Interaction Metabolic Interaction Signaling Interaction |
Physical Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
in same component |
IP6K2 | IMID; |
interacts with |
EEA1 | INTACT; |
interacts with |
ELANE | MINT; |
interacts with |
SERPINB9 | BIOGRID; |
interacts with |
SRGN | BIOGRID; |
interacts with |
UBE4A | BIOGRID; |
Metabolic Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
metabolic catalysis |
IL12A | NCI_NATURE; |
metabolic catalysis |
IL12B | NCI_NATURE; |
metabolic catalysis |
IL12RB1 | NCI_NATURE; |
metabolic catalysis |
IL12RB2 | NCI_NATURE; |
metabolic catalysis |
IL2 | NCI_NATURE; |
metabolic catalysis |
IL2RA | NCI_NATURE; |
metabolic catalysis |
IL2RB | NCI_NATURE; |
metabolic catalysis |
IL2RG | NCI_NATURE; |
metabolic catalysis |
JAK2 | NCI_NATURE; |
metabolic catalysis |
TYK2 | NCI_NATURE; |
sequential catalysis |
GZMB | IMID; |
sequential catalysis |
GZMB | REACTOME; |
Signaling Interaction [Top] | ||
Interaction Type | Interactor | Data Source |
|---|---|---|
reacts with |
GZMB | IMID; |
reacts with |
IP6K2 | IMID; |
state change |
PRF1 | NCI_NATURE; |