| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 9641 |
Name | IKBKE |
Synonym | IKK-E|IKK-i|IKKE|IKKI;inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon;IKBKE;inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon |
Definition | I-kappa-B kinase epsilon|IKK-epsilon|IKK-related kinase epsilon|inducible I kappa-B kinase|inducible IkappaB kinase|inhibitor of nuclear factor kappa-B kinase subunit epsilon |
Position | 1q32.1 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Signaling in Immune system;Reactome;REACT:6900 |
Pathway | Toll-like receptor signaling pathway;KEGG PATHWAY;hsa04620 |
Pathway | RIG-I-like receptor signaling pathway;KEGG PATHWAY;hsa04622 |
Pathway | Cytosolic DNA-sensing pathway;KEGG PATHWAY;hsa04623 |
Pathway | Hepatitis C;KEGG PATHWAY;hsa05160 |
Pathway | Toll receptor signaling pathway;PANTHER;P00054 |
Disease | Infection;FunDO |
Disease | Breast cancer;FunDO |
Disease | Squamous cell cancer;FunDO |
Disease | Polyarthritis;FunDO |
Disease | Rheumatoid arthritis;FunDO |
External Links | |
Links to Entrez Gene | 9641 |
Links to all GeneRIF Items | 9641 |
Links to iHOP | 9641 |
Sequence Information | |
Nucleotide Sequence | >9641 : length: 3492 AGATGCCAAAACAGCACCCAGCTGCCCATCAAGATTACCAGAAGGGCCCCAGTTCCTGGC TTCTCTGTGGCTCACACTCTGGTCCTATTGCCTACCCTTGGGAACTCAGAGCATCCTCTT TCTCTTTTCTGCTGAGCTGGTGGCTGCACCGAGTTGCCTCTGTCTCTTTAAGAGAGAAAG AGAGAGCGAGAGACGGAAATCAGGAAGTGCGAGAGAGCTGAGAGCCAGGACTCAGTGCTG AGCTTGGTGTCCCACCGCCACAAGGAGGCAGGGAAGAAACCCACTAGTCCCAGCTCCTGG GGTGGCACAGACATTGCAACTGGCCCTGCCTGTGGGTCCTAGGGGCCCTTGGCTACCAGG AGGCTAAGAACACTGCTCATGAATGACAGTGAGCCCTGAAAGCTCTGGGGGTGTCACCCA GTCCCACAAGCCTGCATCCCCTGCAGTGGAGATGGGCTCAGCTCCTGGACGTGCCACAGA CAGAAAGCATAACATACACTCGCCAGGAAGAGCCTTTGCCTGACTCAGGGCAGCTCAGAG TGTGGGGCAGAAGGTGACCAGCCAGCTCAGGGCAGGAGATGCAGAGCACAGCCAATTACC TGTGGCACACAGATGACCTGCTGGGGCAGGGGGCCACTGCCAGTGTGTACAAGGCCCGCA ACAAGAAATCCGGAGAGCTGGTTGCTGTGAAGGTCTTCAACACTACCAGCTACCTGCGGC CCCGCGAGGTGCAGGTGAGGGAGTTTGAGGTCCTGCGGAAGCTGAACCACCAGAACATTG TCAAGCTCTTTGCGGTGGAGGAGACGGGCGGAAGCCGGCAGAAGGTACTGGTGATGGAGT ACTGCTCCAGTGGGAGCCTGCTGAGTGTGCTGGAGAGCCCTGAGAATGCCTTTGGGCTGC CTGAGGATGAGTTCCTGGTGGTGCTGCGCTGTGTGGTGGCCGGCATGAACCACCTGCGGG AGAACGGCATTGTGCATCGCGACATCAAGCCGGGGAACATCATGCGCCTCGTAGGGGAGG AGGGGCAGAGCATCTACAAGCTGACAGACTTCGGCGCTGCCCGGGAGCTGGATGATGATG AGAAGTTCGTCTCGGTCTATGGGACTGAGGAGTACCTGCATCCCGACATGTATGAGCGGG CGGTGCTTCGAAAGCCCCAGCAAAAAGCGTTCGGGGTGACTGTGGATCTCTGGAGCATTG GAGTGACCTTGTACCATGCAGCCACTGGCAGCCTGCCCTTCATCCCCTTTGGTGGGCCAC GGCGGAACAAGGAGATCATGTACCGGATCACCACGGAGAAGCCGGCTGGGGCCATTGCAG GTGCCCAGAGGCGGGAGAACGGGCCCCTGGAGTGGAGCTACACCCTCCCCATCACCTGCC AGCTGTCACTGGGGCTGCAGAGCCAGCTGGTGCCCATCCTGGCCAACATCCTGGAGGTGG AGCAGGCCAAGTGCTGGGGCTTCGACCAGTTCTTTGCGGAGACCAGTGACATCCTGCAGC GAGTTGTCGTCCATGTCTTCTCCCTGTCCCAGGCAGTCCTGCACCACATCTATATCCATG CCCACAACACGATAGCCATTTTCCAGGAGGCCGTGCACAAGCAGACCAGTGTGGCCCCCC GACACCAGGAGTACCTCTTTGAGGGTCACCTCTGTGTCCTCGAGCCCAGCGTCTCAGCAC AGCACATCGCCCACACGACGGCAAGCAGCCCCCTGACCCTCTTCAGCACAGCCATCCCTA AGGGGCTGGCCTTCAGGGACCCTGCTCTGGACGTCCCCAAGTTCGTCCCCAAAGTGGACC TGCAGGCGGATTACAACACTGCCAAGGGCGTGTTGGGCGCCGGCTACCAGGCCCTGCGGC TGGCACGGGCCCTGCTGGATGGGCAGGAGCTAATGTTTCGGGGGCTGCACTGGGTCATGG AGGTGCTCCAGGCCACATGCAGACGGACTCTGGAAGTGGCAAGGACATCCCTCCTCTACC TCAGCAGCAGCCTGGGAACTGAGAGGTTCAGCAGCGTGGCTGGAACGCCTGAGATCCAGG AACTGAAGGCGGCTGCAGAACTGAGGTCCAGGCTGCGGACTCTAGCGGAGGTCCTCTCCA GATGCTCCCAAAATATCACGGAGACCCAGGAGAGCCTGAGCAGCCTGAACCGGGAGCTGG TGAAGAGCCGGGATCAGGTACATGAGGACAGAAGCATCCAGCAGATTCAGTGCTGTTTGG ACAAGATGAACTTCATCTACAAACAGTTCAAGAAGTCTAGGATGAGGCCAGGGCTTGGCT ACAACGAGGAGCAGATTCACAAGCTGGATAAGGTGAATTTCAGTCATTTAGCCAAAAGAC TCCTGCAGGTGTTCCAGGAGGAGTGCGTGCAGAAGTATCAAGCGTCCTTAGTCACACACG GCAAGAGGATGAGGGTGGTGCACGAGACCAGGAACCACCTGCGCCTGGTTGGCTGTTCTG TGGCTGCCTGTAACACAGAAGCCCAGGGGGTCCAGGAGAGTCTCAGCAAGCTCCTGGAAG AGCTATCTCACCAGCTCCTTCAGGACCGAGCAAAGGGGGCTCAGGCCTCGCCGCCTCCCA TAGCTCCTTACCCCAGCCCTACACGAAAGGACCTGCTTCTCCACATGCAAGAGCTCTGCG AGGGGATGAAGCTGCTGGCATCTGACCTCCTGGACAACAACCGCATCATCGAACGGCTAA ATAGAGTCCCAGCACCTCCTGATGTCTGAGCTCCATGGGGCACATGAGGCATCCTGAAGC ATTAGAATGATTCCAACACTGCTCTTCTGCACCATGAGACCAACCCAGGGCAAGATCCCA TCCCATCACATCAGCCTACCTCCCTCCTGGCTGCTGGCCAGGATGTCGCCAGCATTACCT TCCACTGCCTTTCTCCCTGGGAAGCAGCACAGCTGAGACTGGGCACCAGGCCACCTCTGT TGGGACCCACAGGAAAGAGTGTGGCAGCAACTGCCTGGCTGACCTTTCTATCTTCTCTAG GCTCAGGTACTGCTCCTCCATGCCCATGGCTGGGCCGTGGGGAGAAGAAGCTCTCATACG CCTTCCCACTCCCTCTGGTTTATAGGACTTCACTCCCTAGCCAACAGGAGAGGAGGCCTC CTGGGGTTTCCCCAGGGCAGTAGGTCAAACGACCTCATCACAGTCTTCCTTCCTCTTCAA GCGTTTCATGTTGAACACAGCTCTCTCCGCTCCCTTGTGATTTCTGAGGGTCACCACTGC CAGCCTCAGGCAACATAGAGAGCCTCCTGTTCTTTCTATGCTTGGTCTGACTGAGCCTAA AGTTGAGAAAATGGGTGGCCAAGGCCAGTGCCAGTGTCTTGGGGCCCCTTTGGCTCTCCC TCACTCTCTGAGGCTCCAGCTGGTCCTGGGACATGCAGCCAGGACTGTGAGTCTGGGCAG GTCCAAGGCCTGCACCTTCAAGAAGTGGAATAAATGTGGCCTTTGCTTCTGTTTAAAAAA AAAAAAAAAAAA |
Protein Sequence | >9641 : length: 716 MQSTANYLWHTDDLLGQGATASVYKARNKKSGELVAVKVFNTTSYLRPREVQVREFEVLR KLNHQNIVKLFAVEETGGSRQKVLVMEYCSSGSLLSVLESPENAFGLPEDEFLVVLRCVV AGMNHLRENGIVHRDIKPGNIMRLVGEEGQSIYKLTDFGAARELDDDEKFVSVYGTEEYL HPDMYERAVLRKPQQKAFGVTVDLWSIGVTLYHAATGSLPFIPFGGPRRNKEIMYRITTE KPAGAIAGAQRRENGPLEWSYTLPITCQLSLGLQSQLVPILANILEVEQAKCWGFDQFFA ETSDILQRVVVHVFSLSQAVLHHIYIHAHNTIAIFQEAVHKQTSVAPRHQEYLFEGHLCV LEPSVSAQHIAHTTASSPLTLFSTAIPKGLAFRDPALDVPKFVPKVDLQADYNTAKGVLG AGYQALRLARALLDGQELMFRGLHWVMEVLQATCRRTLEVARTSLLYLSSSLGTERFSSV AGTPEIQELKAAAELRSRLRTLAEVLSRCSQNITETQESLSSLNRELVKSRDQVHEDRSI QQIQCCLDKMNFIYKQFKKSRMRPGLGYNEEQIHKLDKVNFSHLAKRLLQVFQEECVQKY QASLVTHGKRMRVVHETRNHLRLVGCSVAACNTEAQGVQESLSKLLEELSHQLLQDRAKG AQASPPPIAPYPSPTRKDLLLHMQELCEGMKLLASDLLDNNRIIERLNRVPAPPDV |