| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 9564 |
Name | BCAR1 |
Synonym | CAS|CAS1|CASS1|CRKAS|P130Cas;breast cancer anti-estrogen resistance 1;BCAR1;breast cancer anti-estrogen resistance 1 |
Definition | Cas scaffolding protein family member 1|Crk-associated substrate p130Cas|breast cancer anti-estrogen resistance protein 1 |
Position | 16q23.1 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Signaling events regulated by Ret tyrosine kinase;PID Curated;200058 |
Pathway | Regulation of actin cytoskeleton;KEGG PATHWAY;hsa04810 |
Pathway | CXCR4-mediated signaling events;PID Curated;200083 |
Pathway | PDGFR-beta signaling pathway;PID Curated;200127 |
Pathway | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met);PID Curated;200032 |
Pathway | Integrin cell surface interactions;Reactome;REACT:13552 |
Pathway | Signaling events mediated by PRL;PID Curated;200006 |
Pathway | p130Cas linkage to MAPK signaling for integrins;PID Reactome;500007 |
Pathway | Bacterial invasion of epithelial cells;KEGG PATHWAY;hsa05100 |
Pathway | Signaling by PDGF;Reactome;REACT:16888 |
Pathway | pten dependent cell cycle arrest and apoptosis;PID BioCarta;100058 |
Pathway | Focal adhesion;KEGG PATHWAY;hsa04510 |
Pathway | Osteopontin-mediated events;PID Curated;200042 |
Pathway | Leukocyte transendothelial migration;KEGG PATHWAY;hsa04670 |
Pathway | cell to cell adhesion signaling;PID BioCarta;100208 |
Pathway | CDC42 signaling events;PID Curated;200057 |
Pathway | LPA receptor mediated events;PID Curated;200011 |
Pathway | EPHA2 forward signaling;PID Curated;200185 |
Pathway | Endothelins;PID Curated;200004 |
Pathway | Plasma membrane estrogen receptor signaling;PID Curated;200029 |
Pathway | links between pyk2 and map kinases;PID BioCarta;100057 |
Pathway | angiotensin ii mediated activation of jnk pathway via pyk2 dependent signaling;PID BioCarta;100236 |
Pathway | Integrin signalling pathway;PANTHER;P00034 |
Pathway | IGF1 pathway;PID Curated;200084 |
Pathway | Paxillin-independent events mediated by a4b1 and a4b7;PID Curated;200178 |
Pathway | Signaling events mediated by PTP1B;PID Curated;200033 |
Pathway | Hemostasis;Reactome;REACT:604 |
Pathway | erk and pi-3 kinase are necessary for collagen binding in corneal epithelia;PID BioCarta;100184 |
Pathway | Integrins in angiogenesis;PID Curated;200109 |
Pathway | Signaling events mediated by focal adhesion kinase;PID Curated;200192 |
Pathway | integrin signaling pathway;PID BioCarta;100123 |
Pathway | Chemokine signaling pathway;KEGG PATHWAY;hsa04062 |
Pathway | Down-stream signal transduction;PID Reactome;500509 |
Pathway | vegf hypoxia and angiogenesis;PID BioCarta;100006 |
Pathway | RAC1 signaling pathway;PID Curated;200190 |
Pathway | Paxillin-dependent events mediated by a4b1;PID Curated;200117 |
Pathway | Netrin-mediated signaling;PID Curated;200074 |
Disease | Wiskott-Aldrich syndrome;FunDO |
Disease | Cancer;FunDO |
External Links | |
Links to Entrez Gene | 9564 |
Links to all GeneRIF Items | 9564 |
Links to iHOP | 9564 |
Sequence Information | |
Nucleotide Sequence | >9564 : length: 3794 TGGGAGGGGTGGGACACAGGAGTCTGTTTTTTAACTAGCTCCCCAGAGCACCTGAGCAGC AAATCATGGGCTGTCCTAGCCCCTTTTCAGATGAGAAAGGAGCCCAGAGAGGGGAGAGGG CCTGCCAAGGTGGCACATCTGGCCAGGCGCTGCGTAGGCTGAGCCCTGGGGGTCAGACAG AGGGGCAGCTGCAGGCCCACCTGGGCTTGTGTCTTCCATAGGCCATGCTTGAGAATTCTC TGCTGCGTGAAGCCGGGTCTACCCCGCTGCTTCCCTGCCACCAGGGCTGCCTCGTGGCAT CCCATTGCTCAGCCAGTGGCCCAGGATTGTTGACTGAGGGTCCTGTCTGGTCTGGACCAG GCTCGGTCCTATCATCTCCCTGCAGATTGTGCCTCCCTGGCCTGGCCCAGGGGCTCTGGC ACCCTGGTTCTGCTGCATGGGGTGACAGTCACTGACCTGCAACCGAGCAAGGGGCAACTC AGGAGAGCCAAGGTTGTCTCCACTCGGTTTCCCCCGAGTGATTCTTCCTTCTATCTCCCT CATTCCCCCAGTGCCGCTCTCCTACCCCATGTCGCTGAAGCAGATGAGTTGGAGCAGGAC TCAGGAGGGTACTAGGCCCAGGTTTTAGGCTGAACCTAGGAATGAGTAATGAGAGGAGGC AGATCAGCTGGAGGACCAGCCCGAGTCCCCAGATGTCGGCACAATGCAGGGGAAGAACGT GCTGGCCAAAGCGCTCTATGACAATGTGGCCGAGTCCCCGGATGAGCTCTCCTTCCGCAA GGGTGACATCATGACGGTGCTGGAGCAGGACACGCAGGGCCTGGACGGCTGGTGGCTCTG CTCGCTGCATGGGCGCCAGGGCATCGTGCCTGGGAACCGCCTCAAGATCTTGGTGGGCAT GTATGATAAGAAGCCAGCAGGGCCTGGCCCCGGCCCTCCCGCCACCCCGGCCCAGCCTCA GCCTGGCCTCCATGCCCCAGCGCCTCCGGCCTCCCAGTACACGCCCATGCTCCCCAACAC CTACCAGCCCCAGCCAGACAGCGTCTACCTGGTGCCCACTCCCAGCAAGGCTCAGCAAGG CCTCTACCAAGTCCCGGGTCCCAGCCCTCAGTTCCAGTCTCCCCCAGCCAAGCAGACATC CACCTTCTCGAAGCAGACACCCCATCACCCGTTTCCCAGCCCGGCCACAGACCTGTACCA GGTGCCCCCAGGGCCTGGAGGCCCTGCCCAGGATATTTACCAGGTGCCACCTTCTGCCGG GATGGGGCATGACATCTACCAGGTCCCCCCGTCCATGGACACACGCAGCTGGGAGGGCAC GAAGCCCCCGGCAAAGGTGGTGGTGCCCACCCGCGTGGGGCAGGGCTATGTATACGAGGC CGCCCAGCCGGAGCAGGACGAGTACGACATCCCGCGACACCTGCTGGCCCCGGGGCCACA GGACATCTATGATGTGCCCCCGGTTCGGGGGCTGCTTCCCAGCCAGTATGGCCAGGAGGT GTATGACACACCCCCCATGGCTGTCAAGGGTCCCAATGGCCGAGACCCGTTGCTGGAGGT GTATGACGTGCCCCCCAGTGTGGAGAAGGGCCTGCCACCGTCCAACCACCACGCAGTCTA CGACGTTCCTCCATCGGTGAGCAAGGATGTGCCCGATGGCCCACTGCTGCGTGAGGAGAC CTACGATGTGCCCCCCGCCTTCGCCAAGGCCAAGCCCTTTGACCCGGCCCGCACCCCACT GGTACTGGCTGCGCCCCCTCCAGACTCCCCGCCGGCCGAGGACGTGTATGACGTGCCGCC CCCGGCTCCTGACCTCTACGACGTGCCCCCTGGCTTGCGGCGGCCTGGCCCGGGCACCCT GTACGATGTGCCCCGTGAACGGGTGCTTCCTCCTGAGGTGGCTGATGGTGGCGTGGTCGA CAGTGGTGTGTATGCGGTGCCTCCCCCAGCTGAACGTGAAGCCCCGGCAGAGGGCAAGCG CCTGTCGGCCTCCAGCACCGGCAGCACACGCAGCAGCCAGTCTGCGTCCTCCTTGGAGGT GGCAGGGCCGGGCCGGGAACCCCTGGAGCTGGAAGTTGCTGTGGAGGCCCTGGCACGGCT GCAGCAGGGTGTGAGCGCCACCGTTGCCCACCTTCTGGACCTGGCAGGCAGCGCCGGTGC GACTGGGAGCTGGCGTAGCCCCTCTGAGCCACAGGAGCCGCTGGTGCAGGACCTGCAGGC TGCTGTGGCCGCTGTCCAGAGTGCCGTCCACGAGCTGTTGGAGTTTGCCCGCAGCGCGGT GGGCAATGCTGCCCACACATCTGACCGTGCCCTGCATGCCAAGCTTAGCCGGCAGCTGCA GAAGATGGAGGACGTGCACCAGACGCTGGTGGCACATGGTCAGGCCCTCGACGCTGGCCG GGGAGGCTCTGGAGCCACCCTTGAGGACCTGGACCGGCTGGTGGCCTGCTCGCGGGCTGT GCCCGAGGACGCCAAGCAGCTGGCCTCCTTCCTGCACGGCAATGCCTCACTGCTCTTCAG ACGGACCAAGGCCACTGCCCCGGGGCCTGAGGGGGGTGGCACCCTGCACCCCAACCCCAC TGACAAGACCAGCAGCATCCAGTCACGACCCCTGCCCTCACCCCCTAAGTTCACCTCCCA GGACTCGCCAGATGGGCAGTACGAGAACAGCGAGGGGGGCTGGATGGAGGACTATGACTA CGTCCACCTACAGGGGAAGGAGGAGTTTGAGAAGACCCAGAAGGAGCTGCTGGAAAAGGG CAGCATCACGCGGCAGGGCAAGAGCCAGCTGGAGTTGCAGCAGCTGAAGCAGTTTGAACG ACTGGAACAGGAGGTGTCACGGCCCATAGACCACGACCTGGCCAACTGGACGCCAGCCCA ACCCCTGGCCCCGGGGCGAACAGGCGGCCTGGGGCCCTCGGACCGGCAGCTGCTGCTCTT CTACCTGGAGCAGTGTGAGGCCAACCTGACCACACTGACCAACGCCGTGGACGCCTTCTT TACCGCCGTGGCCACCAACCAGCCGCCCAAGATCTTTGTGGCGCACAGCAAGTTCGTCAT CCTCAGCGCCCACAAGCTGGTGTTCATCGGGGACACACTGTCACGGCAGGCCAAGGCTGC TGACGTGCGCAGCCAGGTGACCCACTACAGCAACCTGCTGTGCGACCTCCTGCGCGGCAT CGTGGCCACCACCAAGGCCGCTGCCTTGCAGTACCCATCGCCTTCCGCGGCCCAGGACAT GGTGGAGAGGGTCAAGGAGCTGGGCCACAGCACCCAGCAGTTCCGCCGCGTCCTAGGCCA GCTGGCAGCCGCCTGAGGGTGGTGACCCCAGGAGGGAGGCAGGGGAGGGGTGCGGCGGTC CCAGCTCCCTGGCTCCCATGTCAAGAGTCGCTGTGCCACAGGCTTAGGGACAGGACCCCA GCTCTGCGTCGGTCCTGGTGCCCTGGATGCCCAGGAATCTGTATATATTTATGGCCGGGC AGGGTGTGGGGCCATGCCTCCTCAGGAGCCGAAGCCCAGGGGCCGGCCAGTGGCCTTCCC CAGCATGCACCACGGGCCCGGGTTGGGTCACCAGACGGGGCTGGAGTGTGAGGGTCCTGC AGCCTGCAGGACCTCGTGCCACCCCGAGGGCTGAGCCTGGTCCCACGAGGGTGCCGTGTC CCCTGACAGGGCCAGTGCAGTTTGGTGTGTCCTCCGCCTTACCAGGAGAAGAACCTGAAG AACTATTTTTCGTTATTGGTTTTCCAATCATTTGACTAAGAGTCTCCATTTAAATAAAGT TTTTAAAAGGAAGA |
Protein Sequence | >9564 : length: 920 MCHPPQTSGWHWLGSPCLGVAGAGHPQPCQVRGQLPAAERPPCCLFCFLLPICENVLAKA LYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNRLKILVGMYDKK PAGPGPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQQGLYQV PGPSPQFQSPPAKQTSTFSKQTPHHPFPSPATDLYQVPPGPGGPAQDIYQVPPSAGMGHD IYQVPPSMDTRSWEGTKPPAKVVVPTRVGQGYVYEAAQPEQDEYDIPRHLLAPGPQDIYD VPPVRGLLPSQYGQEVYDTPPMAVKGPNGRDPLLEVYDVPPSVEKGLPPSNHHAVYDVPP SVSKDVPDGPLLREETYDVPPAFAKAKPFDPARTPLVLAAPPPDSPPAEDVYDVPPPAPD LYDVPPGLRRPGPGTLYDVPRERVLPPEVADGGVVDSGVYAVPPPAEREAPAEGKRLSAS STGSTRSSQSASSLEVAGPGREPLELEVAVEALARLQQGVSATVAHLLDLAGSAGATGSW RSPSEPQEPLVQDLQAAVAAVQSAVHELLEFARSAVGNAAHTSDRALHAKLSRQLQKMED VHQTLVAHGQALDAGRGGSGATLEDLDRLVACSRAVPEDAKQLASFLHGNASLLFRRTKA TAPGPEGGGTLHPNPTDKTSSIQSRPLPSPPKFTSQDSPDGQYENSEGGWMEDYDYVHLQ GKEEFEKTQKELLEKGSITRQGKSQLELQQLKQFERLEQEVSRPIDHDLANWTPAQPLAP GRTGGLGPSDRQLLLFYLEQCEANLTTLTNAVDAFFTAVATNQPPKIFVAHSKFVILSAH KLVFIGDTLSRQAKAADVRSQVTHYSNLLCDLLRGIVATTKAAALQYPSPSAAQDMVERV KELGHSTQQFRRVLGQLAAA |