| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 891 |
Name | CCNB1 |
Synonym | CCNB;cyclin B1;CCNB1;cyclin B1 |
Definition | G2/mitotic-specific cyclin B1|G2/mitotic-specific cyclin-B1 |
Position | 5q12 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | il-2 receptor beta chain in t cell activation;PID BioCarta;100129 |
Pathway | Direct p53 effectors;PID Curated;200101 |
Pathway | FOXM1 transcription factor network;PID Curated;200120 |
Pathway | Phosphorylation of the APC/C;PID Reactome;500395 |
Pathway | akap95 role in mitosis and chromosome dynamics;PID BioCarta;100247 |
Pathway | cell cycle: g2/m checkpoint;PID BioCarta;100159 |
Pathway | APC/C:Cdc20 mediated degradation of Cyclin B;PID Reactome;500397 |
Pathway | Validated targets of C-MYC transcriptional activation;PID Curated;200045 |
Pathway | Cyclin A/B1 associated events during G2/M transition;PID Reactome;500991 |
Pathway | PLK1 signaling events;PID Curated;200087 |
Pathway | p53 pathway;PANTHER;P00059 |
Pathway | Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex;PID Reactome;500318 |
Pathway | Progesterone-mediated oocyte maturation;KEGG PATHWAY;hsa04914 |
Pathway | Phosphorylation of Emi1;PID Reactome;500392 |
Pathway | how progesterone initiates the oocyte maturation;PID BioCarta;100104 |
Pathway | regulation of cell cycle progression by plk3;PID BioCarta;100068 |
Pathway | Recruitment of NuMA to mitotic centrosomes;PID Reactome;500382 |
Pathway | Cell cycle;KEGG PATHWAY;hsa04110 |
Pathway | G2/M DNA replication checkpoint;PID Reactome;500939 |
Pathway | stathmin and breast cancer resistance to antimicrotubule agents;PID BioCarta;100027 |
Pathway | cyclins and cell cycle regulation;PID BioCarta;100207 |
Pathway | sonic hedgehog receptor ptc1 regulates cell cycle;PID BioCarta;100060 |
Pathway | Cell Cycle Checkpoints;Reactome;REACT:1538 |
Pathway | Regulation of APC/C activators between G1/S and early anaphase;PID Reactome;500391 |
Pathway | Oocyte meiosis;KEGG PATHWAY;hsa04114 |
Pathway | FoxO family signaling;PID Curated;200091 |
Pathway | p53 signaling pathway;KEGG PATHWAY;hsa04115 |
Pathway | C-MYB transcription factor network;PID Curated;200130 |
Pathway | Cell Cycle, Mitotic;Reactome;REACT:152 |
Disease | Cancer;FunDO |
External Links | |
Links to Entrez Gene | 891 |
Links to all GeneRIF Items | 891 |
Links to iHOP | 891 |
Sequence Information | |
Nucleotide Sequence | >891 : length: 2177 CGAACGCCTTCGCGCGATCGCCCTGGAAACGCATTCTCTGCGACCGGCAGCCGCCAATGG GAAGGGAGTGAGTGCCACGAACAGGCCAATAAGGAGGGAGCAGTGCGGGGTTTAAATCTG AGGCTAGGCTGGCTCTTCTCGGCGTGCTGCGGCGGAACGGCTGTTGGTTTCTGCTGGGTG TAGGTCCTTGGCTGGTCGGGCCTCCGGTGTTCTGCTTCTCCCCGCTGAGCTGCTGCCTGG TGAAGAGGAAGCCATGGCGCTCCGAGTCACCAGGAACTCGAAAATTAATGCTGAAAATAA GGCGAAGATCAACATGGCAGGCGCAAAGCGCGTTCCTACGGCCCCTGCTGCAACCTCCAA GCCCGGACTGAGGCCAAGAACAGCTCTTGGGGACATTGGTAACAAAGTCAGTGAACAACT GCAGGCCAAAATGCCTATGAAGAAGGAAGCAAAACCTTCAGCTACTGGAAAAGTCATTGA TAAAAAACTACCAAAACCTCTTGAAAAGGTACCTATGCTGGTGCCAGTGCCAGTGTCTGA GCCAGTGCCAGAGCCAGAACCTGAGCCAGAACCTGAGCCTGTTAAAGAAGAAAAACTTTC GCCTGAGCCTATTTTGGTTGATACTGCCTCTCCAAGCCCAATGGAAACATCTGGATGTGC CCCTGCAGAAGAAGACCTGTGTCAGGCTTTCTCTGATGTAATTCTTGCAGTAAATGATGT GGATGCAGAAGATGGAGCTGATCCAAACCTTTGTAGTGAATATGTGAAAGATATTTATGC TTATCTGAGACAACTTGAGGAAGAGCAAGCAGTCAGACCAAAATACCTACTGGGTCGGGA AGTCACTGGAAACATGAGAGCCATCCTAATTGACTGGCTAGTACAGGTTCAAATGAAATT CAGGTTGTTGCAGGAGACCATGTACATGACTGTCTCCATTATTGATCGGTTCATGCAGAA TAATTGTGTGCCCAAGAAGATGCTGCAGCTGGTTGGTGTCACTGCCATGTTTATTGCAAG CAAATATGAAGAAATGTACCCTCCAGAAATTGGTGACTTTGCTTTTGTGACTGACAACAC TTATACTAAGCACCAAATCAGACAGATGGAAATGAAGATTCTAAGAGCTTTAAACTTTGG TCTGGGTCGGCCTCTACCTTTGCACTTCCTTCGGAGAGCATCTAAGATTGGAGAGGTTGA TGTCGAGCAACATACTTTGGCCAAATACCTGATGGAACTAACTATGTTGGACTATGACAT GGTGCACTTTCCTCCTTCTCAAATTGCAGCAGGAGCTTTTTGCTTAGCACTGAAAATTCT GGATAATGGTGAATGGACACCAACTCTACAACATTACCTGTCATATACTGAAGAATCTCT TCTTCCAGTTATGCAGCACCTGGCTAAGAATGTAGTCATGGTAAATCAAGGACTTACAAA GCACATGACTGTCAAGAACAAGTATGCCACATCGAAGCATGCTAAGATCAGCACTCTACC ACAGCTGAATTCTGCACTAGTTCAAGATTTAGCCAAGGCTGTGGCAAAGGTGTAACTTGT AAACTTGAGTTGGAGTACTATATTTACAAATAAAATTGGCACCATGTGCCATCTGTACAT ATTACTGTTGCATTTACTTTTAATAAAGCTTGTGGCCCCTTTTACTTTTTTATAGCTTAA CTAATTTGAATGTGGTTACTTCCTACTGTAGGGTAGCGGAAAAGTTGTCTTAAAAGGTAT GGTGGGGATATTTTTAAAAACTCCTTTTGGTTTACCTGGGGATCCAATTGATGTATATGT TTATATACTGGGTTCTTGTTTTATATACCTGGCTTTTACTTTATTAATATGAGTTACTGA AGGTGATGGAGGTATTTGAAAATTTTACTTCCATAGGACATACTGCATGTAAGCCAAGTC ATGGAGAATCTGCTGCATAGCTCTATTTTAAAGTAAAAGTCTACCACCGAATCCCTAGTC CCCCTGTTTTCTGTTTCTTCTTGTGATTGCTGCCATAATTCTAAGTTATTTACTTTTACC ACTATTTAAGTTATCAACTTTAGCTAGTATCTTCAAACTTTCACTTTGAAAAATGAGAAT TTTATATTCTAAGCCAGTTTTCATTTTGGTTTTGTGTTTTGGTTAATAAAACAATACTCA AATACAAAAAAAAAAAA |
Protein Sequence | >891 : length: 433 MALRVTRNSKINAENKAKINMAGAKRVPTAPAATSKPGLRPRTALGDIGNKVSEQLQAKM PMKKEAKPSATGKVIDKKLPKPLEKVPMLVPVPVSEPVPEPEPEPEPEPVKEEKLSPEPI LVDTASPSPMETSGCAPAEEDLCQAFSDVILAVNDVDAEDGADPNLCSEYVKDIYAYLRQ LEEEQAVRPKYLLGREVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVP KKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRP LPLHFLRRASKIGEVDVEQHTLAKYLMELTMLDYDMVHFPPSQIAAGAFCLALKILDNGE WTPTLQHYLSYTEESLLPVMQHLAKNVVMVNQGLTKHMTVKNKYATSKHAKISTLPQLNS ALVQDLAKAVAKV |