| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 7168 |
Name | TPM1 |
Synonym | C15orf13|CMD1Y|CMH3|HTM-alpha|LVNC9|TMSA;tropomyosin 1 (alpha);TPM1;tropomyosin 1 (alpha) |
Definition | alpha-tropomyosin|cardiomyopathy, hypertrophic 3|sarcomeric tropomyosin kappa|tropomyosin alpha-1 chain |
Position | 15q22.1 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Muscle contraction;Reactome;REACT:17044 |
Pathway | Cardiac muscle contraction;KEGG PATHWAY;hsa04260 |
Pathway | Dilated cardiomyopathy;KEGG PATHWAY;hsa05414 |
Pathway | Hypertrophic cardiomyopathy (HCM);KEGG PATHWAY;hsa05410 |
Disease | Mean platelet volume;NHGRI |
Disease | nemaline myopathy;GAD |
Disease | Circulatory system diseases;KEGG DISEASE |
Disease | Primary tumor;FunDO |
Disease | Hypertrophic cardiomyopathy (HCM);KEGG DISEASE;H00292 |
Disease | Cardiac diseases;KEGG DISEASE |
Disease | CARDIOVASCULAR;GAD |
Disease | Cardiomyopathy, familial hypertrophic, 3;OMIM |
Disease | cardiovascular;GAD |
Disease | HEMATOLOGICAL;GAD |
Disease | Cardiomyopathy, dilated, 1Y;OMIM |
Disease | Dilated cardiomyopathy (DCM);KEGG DISEASE;H00294 |
Disease | Breast cancer;FunDO |
Disease | mean platelet volume;GAD |
External Links | |
Links to Entrez Gene | 7168 |
Links to all GeneRIF Items | 7168 |
Links to iHOP | 7168 |
Sequence Information | |
Nucleotide Sequence | >7168 : length: 2362 GCACAGAGAGGCCTGGGCGGGGCGGACCGGCGCTGGGCAGCCAGGACAGCCGCGGCAGCC GGGTCCGCAGGGCAGCAGCCGGCCTCTCCCACTGCAGCCCTCCCGCCCGCCTACCGTCCG GCGCGATGGCGGGGAGTAGCTCGCTGGAGGCGGTGCGCAGGAAGATCCGGAGCCTGCAGG AGCAGGCGGACGCCGCTGAGGAGCGCGCGGGCACCCTGCAGCGCGAGCTGGACCACGAGA GGAAGCTGAGGGAGACCGCTGAAGCCGACGTAGCTTCTCTGAACAGACGCATCCAGCTGG TTGAGGAAGAGTTGGATCGTGCCCAGGAGCGTCTGGCAACAGCTTTGCAGAAGCTGGAGG AAGCTGAGAAGGCAGCAGATGAGAGTGAGAGAGGCATGAAAGTCATTGAGAGTCGAGCCC AAAAAGATGAAGAAAAAATGGAAATTCAGGAGATCCAACTGAAAGAGGCCAAGCACATTG CTGAAGATGCCGACCGCAAATATGAAGAGGTGGCCCGTAAGCTGGTCATCATTGAGAGCG ACCTGGAACGTGCAGAGGAGCGGGCTGAGCTCTCAGAAGGCAAATGTGCCGAGCTTGAAG AAGAATTGAAAACTGTGACGAACAACTTGAAGTCACTGGAGGCTCAGGCTGAGAAGTACT CGCAGAAGGAAGACAGATATGAGGAAGAGATCAAGGTCCTTTCCGACAAGCTGAAGGAGG CTGAGACTCGGGCTGAGTTTGCGGAGAGGTCAGTAACTAAATTGGAGAAAAGCATTGATG ACTTAGAAGACGAGCTGTACGCTCAGAAACTGAAGTACAAAGCCATCAGCGAGGAGCTGG ACCACGCTCTCAACGATATGACTTCCATGTAAACGTTCATCCACTCTGCCTGCTTACACC CTGCCCTCATGCTAATGTAATAAACTCACCACCATGCCTTCCTTGCTCCCTAATCTCCAT CTTTGCACTCTTGTGTTCACCCTTTTTGTCATAACCTAGAATAGTCATTGTTTTTTCACT TTCTGCTAATATAAAGGCCAATTAGATTAAGTCTGTCTATACAAACCATTTTCTTTTCAG AATCCGTTTATTTTGTAAACGCTGAACTAGAGCAGTGAACTAGAATGAGTGACCTTGAGC ACTGTCCTTTTGGGAAATTAAGCTAAACTCAAGTAAAACTAGAAGGCCATGCCGTTTGTT GTACAGGAACTTCTCAAAAAATATCAAAATTTGTTTCCTGAAATTCAACTAAGTACAACA TAATCATTTTCGTTAAATATAATTTGAAGGAACCCTTAAAGTGTCAGGTTATTGAGAATC TGAGGATAAGGAAATTGGCATGATCCAATACAGCTTTAACAGTGGTACTACAAAAGATCA TCTCTTTTACTTTTAAGAATTCTAGAGTAGGCCGGGCACAGTGGCTCACGCCTGTAATCC CAGCACTTTGGGAGGCCGAGGCGGGCGGATCACGAGGTCAGGAGATTGAGACCATCCTGG CTAACACGGTGAAACCCTGTCTCTACTAAAAATACAAAAAAAATTAGCCGGGCGTGGTGG TGGATGCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATGGCATGAACCCGGG AGGTGGAGCTTGCAGTCAGCCGAGATCGCACCACCGCACTCCAGCCTGGACGACAGAGCG AGACTCTGTCTCAAGAAAAAAAAGAATGGTAGAGTAAAAAGAACCCTCTGCTGAGTAACC AAGCCTTTAATTTTGTGTTTTTATGAAAGGAATTAAAATACCCACGATAAATATTTACCA CAACCTGTGTCAAATAAATGGGAAATTAAACACAGATTGTACAATGTGAGCTTGGGAGTT AATGGCCCAGATTTTACTGTTAGGCAGTAAGAGTTGGAGTAGGTAGTCTTGTTATCATGA GAAGAACCTTGAACAGATACAACTAATTTACATATTACTAACCAAACTTAAACATTAAAC TTTTTCTACTACTTTAAATTCTAACCTGGAATGTTTCAGAGTTCTTCATTCTAATATCAC CCTGAATTCCATTGAAGCTGGAAATGTCATTTTCCAAGCCCACCTGTCATTCATTTACCC ATGCAGAAAAAATGGTAACTTGAAGAGAGTGGCATGTGCCTGCTGCCTTAGAGGTTATAG AATCCCCACAGTCAACAAAAAAGCCTCTAGAGACATGACTGTTGCCATGGAAACCAGAGA AAATGTGTCTTCTCATCCCTCATTTGTAAATGAGGGGGTGGAGCAGATCATCTGTCTCTA AGGTCTTTTTCAGTGCTAAAATGTGGTGATTCTTTGGGAAAAACTTTTTGCATCAAGTAT GATTAAATATTCTGAAAGACGA |
Protein Sequence | >7168 : length: 326 MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEEDIAAKEKLLRVSEDERDRV LEELHKAEDSLLAAEEAAAKLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKA TDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDE EKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELK TVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEE KVAHAKEENLSMHQMLDQTLLELNNM |