| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 5771 |
Name | PTPN2 |
Synonym | PTN2|PTPT|TC-PTP|TCELLPTP|TCPTP;protein tyrosine phosphatase, non-receptor type 2;PTPN2;protein tyrosine phosphatase, non-receptor type 2 |
Definition | T-cell protein tyrosine phosphatase|tyrosine-protein phosphatase non-receptor type 2 |
Position | 18p11.3-p11.2 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | PDGFR-beta signaling pathway;PID Curated;200127 |
Pathway | Signaling events mediated by TCPTP;PID Curated;200065 |
Pathway | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met);PID Curated;200032 |
Pathway | IFN-gamma pathway;PID Curated;200110 |
Disease | IMMUNE;GAD |
Disease | Metabolic diseases;KEGG DISEASE |
Disease | Type 1 diabetes;NHGRI |
Disease | Celiac disease;NHGRI |
Disease | type 1 diabetes;GAD |
Disease | Type I diabetes mellitus;KEGG DISEASE;H00408 |
Disease | Celiac Disease;GAD |
Disease | Crohn's;GAD |
Disease | Crohn's disease;GAD |
Disease | Crohn's disease;NHGRI |
Disease | Diabetes;KEGG DISEASE |
Disease | Ulcerative colitis;FunDO |
External Links | |
Links to Entrez Gene | 5771 |
Links to all GeneRIF Items | 5771 |
Links to iHOP | 5771 |
Sequence Information | |
Nucleotide Sequence | >5771 : length: 3418 GCTCGGGCGCCGAGTCTGCGCGCTGACGTCCGACGCTCCAGGTACTTTCCCCACGGCCGA CAGGGCTTGGCGTGGGGGCGGGGCGCGGCGCGCAGCGCGCATGCGCCGCAGCGCCAGCGC TCTCCCCGGATCGTGCGGGGCCTGAGCCTCTCCGCCGGCGCAGGCTCTGCTCGCGCCAGC TCGCTCCCGCAGCCATGCCCACCACCATCGAGCGGGAGTTCGAAGAGTTGGATACTCAGC GTCGCTGGCAGCCGCTGTACTTGGAAATTCGAAATGAGTCCCATGACTATCCTCATAGAG TGGCCAAGTTTCCAGAAAACAGAAATCGAAACAGATACAGAGATGTAAGCCCATATGATC ACAGTCGTGTTAAACTGCAAAATGCTGAGAATGATTATATTAATGCCAGTTTAGTTGACA TAGAAGAGGCACAAAGGAGTTACATCTTAACACAGGGTCCACTTCCTAACACATGCTGCC ATTTCTGGCTTATGGTTTGGCAGCAGAAGACCAAAGCAGTTGTCATGCTGAACCGCATTG TGGAGAAAGAATCGGTTAAATGTGCACAGTACTGGCCAACAGATGACCAAGAGATGCTGT TTAAAGAAACAGGATTCAGTGTGAAGCTCTTGTCAGAAGATGTGAAGTCGTATTATACAG TACATCTACTACAATTAGAAAATATCAATAGTGGTGAAACCAGAACAATATCTCACTTTC ATTATACTACCTGGCCAGATTTTGGAGTCCCTGAATCACCAGCTTCATTTCTCAATTTCT TGTTTAAAGTGAGAGAATCTGGCTCCTTGAACCCTGACCATGGGCCTGCGGTGATCCACT GTAGTGCAGGCATTGGGCGCTCTGGCACCTTCTCTCTGGTAGACACTTGTCTTGTTTTGA TGGAAAAAGGAGATGATATTAACATAAAACAAGTGTTACTGAACATGAGAAAATACCGAA TGGGTCTTATTCAGACCCCAGATCAACTGAGATTCTCATACATGGCTATAATAGAAGGAG CAAAATGTATAAAGGGAGATTCTAGTATACAGAAACGATGGAAAGAACTTTCTAAGGAAG ACTTATCTCCTGCCTTTGATCATTCACCAAACAAAATAATGACTGAAAAATACAATGGGA ACAGAATAGGTCTAGAAGAAGAAAAACTGACAGGTGACCGATGTACAGGACTTTCCTCTA AAATGCAAGATACAATGGAGGAGAACAGTGAGAGTGCTCTACGGAAACGTATTCGAGAGG ACAGAAAGGCCACCACAGCTCAGAAGGTGCAGCAGATGAAACAGAGGCTAAATGAGAATG AACGAAAAAGAAAAAGGTGGTTATATTGGCAACCTATTCTCACTAAGATGGGGTTTATGT CAGTCATTTTGGTTGGCGCTTTTGTTGGCTGGACACTGTTTTTTCAGCAAAATGCCCTAT AAACAATTAATTTTGCCCAGCAAGCTTCTGCACTAGTAACTGACAGTGCTACATTAATCA TAGGGGTTTGTCTGCAGCAAACGCCTCATATCCCAAAAACGGTGCAGTAGAATAGACATC AACCAGATAAGTGATATTTACAGTCACAAGCCCAACATCTCAGGACTCTTGACTGCAGGT TCCTCTGAACCCCAAACTGTAAATGGCTGTCTAAAATAAAGACATTCATGTTTGTTAAAA ACTGGTAAATTTTGCAACTGTATTCATACATGTCAAACACAGTATTTCACCTGACCAACA TTGAGATATCCTTTATCACAGGATTTGTTTTTGGAGGCTATCTGGATTTTAACCTGCACT TGATATAAGCAATAAATATTGTGGTTTTATCTACGTTATTGGAAAGAAAATGACATTTAA ATAATGTGTGTAATGTATAATGTACTATTGACATGGGCATCAACACTTTTATTCTTAAGC ATTTCAGGGTAAATATATTTTATAAGTATCTATTTAATCTTTTGTAGTTAACTGTACTTT TTAAGAGCTCAATTTGAAAAATCTGTTACTAAAAAAATAAATTGTATGTCGATTGAATTG TACTGGATACATTTTCCATTTTTCTAAAGAGAAGTTTGATATGAGCAGTTAGAAGTTGGA ATAAGCAATTTCTACTATATATTGCATTTCTTTTATGTTTTACAGTTTTCCCCATTTTAA AAAGAAAAGCAAACAAAGAAACAAAAGTTTTTCCTAAAAATATCTTTGAAGGAAAATTCT CCTTACTGGGATAGTCAGGTAAACAGTTGGTCAAGACTTTGTAAAGAAATTGGTTTCTGT AAATCCCATTATTGATATGTTTATTTTTCATGAAAATTTCAATGTAGTTGGGGTAGATTA TGATTTAGGAAGCAAAAGTAAGAAGCAGCATTTTATGATTCATAATTTCAGTTTACTAGA CTGAAGTTTTGAAGTAAACACTTTTCAGTTTCTTTCTACTTCAATAAATAGTATGATTAT ATGCAAACCTTACATTGTCATTTTAACTTAATGAATATTTTTTAAAGCAAACTGTTTAAT GAATTTAACTGCTCATTTGAATGCTAGCTTTCCTCAGATTTCAACATTCCATTCAGTGTT TAATTTGTCTTACTTAAACTTGAAATTGTTGTTACAAATTTAATTGCTAGGAGGCATGGA TAGCATACATTATTATGGATAGCATACCTTATTTCAGTGGTTTTCAAACTATGCTCATTG GATGTCCAGGTGGGTCAAGAGGTTACTTTCAACCACAGCATCTCTGCCTTGTCTCTTTAT ATGCCACATAAGATTTCTGCATAAGGCTTAAGTATTTTAAAGGGGGCAGTTATCATTTAA AAACAGTTTGGTCGGGCGCGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCTGAA GTGGGCAGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACGTGGTGAAACACC ATCTCTACTAAAAATGCAAAAATTAGCTGGGCATGGTGGAGGGCACCTGTAATCTCAGCT ACTCAGGAGGCTGAGGTAGGAGAATTGCTTGAACCCAGGAGATGGAGGTTGCAGTGAGCT GAGATCACGTCACTGCACTCCAGCCAGGGCGACAGAGCGAGACTCCATCTCAAAAGAAAC AAACAAAAAAAACAGTTTGGGCCGGGTGTGGTGGCTCACGCTTGTAATCCCAGCACTTCG GAAGGCCAAGGCGGGCGGATCACGAGGTCAAGAGATGGAGACTGTCCTGGCCAACATGGT GAAATCCCTTCTTTACTAAAAATACAAAAATTATCTGGGCGTGGTGGTGCATGCCTGTAG TCCCAGCTCCTTGGGAGGCTAAGGCAGGAGAATCACTTGAACCCGGGAGGCAGAGGTTGC AGTGAGCCGAGATTGCACCACTGCACTCCAGCCTGGCAACAGAGCAAGACTTCGTCTC |
Protein Sequence | >5771 : length: 438 MPTTIEREFEELDTQRRWQPLYLEIRNESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVK LQNAENDYINASLVDIEEAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKES VKCAQYWPTDDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENINYIENLWITLYLKLLM LDVKRSLKSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCS AGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAK CIKGDSSIQKRWKELSKEDLSPAFDHSPNKIMTEKYNGNRIGLEEEKLTGDRCTGLSSKM QDTMEENSESALRKRIREDRKATTAQKVQQMKQRLNENERKRKRWLYWQPILTKMGFMSV ILVGAFVGWTLFFQQNAL |