| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 5745 |
Name | PTH1R |
Synonym | PFE|PTHR|PTHR1;parathyroid hormone 1 receptor;PTH1R;parathyroid hormone 1 receptor |
Definition | PTH/PTHr receptor|PTH/PTHrP type I receptor|PTH1 receptor|parathyroid hormone receptor 1|parathyroid hormone/parathyroid hormone-related peptide receptor|parathyroid hormone/parathyroid hormone-related protein receptor|seven transmembrane helix receptor |
Position | 3p22-p21.1 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Signaling by GPCR;Reactome;REACT:14797 |
Pathway | Neuroactive ligand-receptor interaction;KEGG PATHWAY;hsa04080 |
Disease | bone density height;GAD |
Disease | METABOLIC;GAD |
Disease | bone density;GAD |
Disease | pyridinoline, urinary;GAD |
Disease | Bone disease;FunDO |
Disease | Eiken syndrome;OMIM |
Disease | Chondrodysplasia, Blomstrand type;OMIM |
Disease | Failure of tooth eruption, primary;OMIM |
Disease | CANCER;GAD |
Disease | Cancer;FunDO |
Disease | Rheumatism;FunDO |
Disease | Kidney failure;FunDO |
Disease | Oral cancer;FunDO |
Disease | malignancy;GAD |
Disease | Metaphyseal chondrodysplasia, Murk Jansen type;OMIM |
Disease | height;GAD |
Disease | PTH;GAD |
External Links | |
Links to Entrez Gene | 5745 |
Links to all GeneRIF Items | 5745 |
Links to iHOP | 5745 |
Sequence Information | |
Nucleotide Sequence | >5745 : length: 2196 CAGCAGCACTATCCTTGCTTAGGCCTGAGCCACAGAAGCTGCTCAGGGACTATCCATGGC CTCCCCGTGGCCAACTTGAGTCTGCTCTGCAGCTTTAGGCCCGACTTGGAAGGCCCATGG GCTGCAGATGAGGAAACTGAGGTCCAGACAGCCGAAGAGTGGTAGTGTCCAGGACACACA ACTGGGCCGGCGGCGGCGGCTGCCCCGAGGGACGCGGCCCTAGGCGGTGGCGATGGGGAC CGCCCGGATCGCACCCGGCCTGGCGCTCCTGCTCTGCTGCCCCGTGCTCAGCTCCGCGTA CGCGCTGGTGGATGCAGATGACGTCATGACTAAAGAGGAACAGATCTTCCTGCTGCACCG TGCTCAGGCCCAGTGCGAAAAACGGCTCAAGGAGGTCCTGCAGAGGCCAGCACAGCTGAC AGCCATCATTACCACCCTGGTTTCTCCAGCCAGCATAATGGAATCAGACAAGGGATGGAC ATCTGCGTCCACATCAGGGAAGCCCAGGAAAGATAAGGCATCTGGGAAGCTCTACCCTGA GTCTGAGGAGGACAAGGAGGCACCCACTGGCAGCAGGTACCGAGGGCGCCCCTGTCTGCC GGAATGGGACCACATCCTGTGCTGGCCGCTGGGGGCACCAGGTGAGGTGGTGGCTGTGCC CTGTCCGGACTACATTTATGACTTCAATCACAAAGGCCATGCCTACCGACGCTGTGACCG CAATGGCAGCTGGGAGCTGGTGCCTGGGCACAACAGGACGTGGGCCAACTACAGCGAGTG TGTCAAATTTCTCACCAATGAGACTCGTGAACGGGAGGTGTTTGACCGCCTGGGCATGAT TTACACCGTGGGCTACTCCGTGTCCCTGGCGTCCCTCACCGTAGCTGTGCTCATCCTGGC CTACTTTAGGCGGCTGCACTGCACGCGCAACTACATCCACATGCACCTGTTCCTGTCCTT CATGCTGCGCGCCGTGAGCATCTTCGTCAAGGACGCTGTGCTCTACTCTGGCGCCACGCT TGATGAGGCTGAGCGCCTCACCGAGGAGGAGCTGCGCGCCATCGCCCAGGCGCCCCCGCC GCCTGCCACCGCCGCTGCCGGCTACGCGGGCTGCAGGGTGGCTGTGACCTTCTTCCTTTA CTTCCTGGCCACCAACTACTACTGGATTCTGGTGGAGGGGCTGTACCTGCACAGCCTCAT CTTCATGGCCTTCTTCTCAGAGAAGAAGTACCTGTGGGGCTTCACAGTCTTCGGCTGGGG TCTGCCCGCTGTCTTCGTGGCTGTGTGGGTCAGTGTCAGAGCTACCCTGGCCAACACCGG GTGCTGGGACTTGAGCTCCGGGAACAAAAAGTGGATCATCCAGGTGCCCATCCTGGCCTC CATTGTGCTCAACTTCATCCTCTTCATCAATATCGTCCGGGTGCTCGCCACCAAGCTGCG GGAGACCAACGCCGGCCGGTGTGACACACGGCAGCAGTACCGGAAGCTGCTCAAATCCAC GCTGGTGCTCATGCCCCTCTTTGGCGTCCACTACATTGTCTTCATGGCCACACCATACAC CGAGGTCTCAGGGACGCTCTGGCAAGTCCAGATGCACTATGAGATGCTCTTCAACTCCTT CCAGGGATTTTTTGTCGCAATCATATACTGTTTCTGCAATGGCGAGGTACAAGCTGAGAT CAAGAAATCTTGGAGCCGCTGGACACTGGCACTGGACTTCAAGCGAAAGGCACGCAGCGG GAGCAGCAGCTATAGCTACGGCCCCATGGTGTCCCACACAAGTGTGACCAATGTCGGCCC CCGTGTGGGACTCGGCCTGCCCCTCAGCCCCCGCCTACTGCCCACTGCCACCACCAACGG CCACCCTCAGCTGCCTGGCCATGCCAAGCCAGGGACCCCAGCCCTGGAGACCCTCGAGAC CACACCACCTGCCATGGCTGCTCCCAAGGACGATGGGTTCCTCAACGGCTCCTGCTCAGG CCTGGACGAGGAGGCCTCTGGGCCTGAGCGGCCACCTGCCCTGCTACAGGAAGAGTGGGA GACAGTCATGTGACCAGGCGCTGGGGGCTGGACCTGCTGACATAGTGGATGGACAGATGG ACCAAAAGATGGGTGGTTGAATGATTTCCCACTCAGGGCTGGGGCCAAGAGGAAAAACAG GGAAAAAAAGAAAAAAAAAAGAAAAAGGAAAAGGAA |
Protein Sequence | >5745 : length: 606 MGTARIAPGLALLLCCPVLSSAYALVDADDVMTKEEQIFLLHRAQAQCEKRLKEVLQRPA QLTAIITTLVSPASIMESDKGWTSASTSGKPRKDKASGKLYPESEEDKEAPTGSRYRGRP CLPEWDHILCWPLGAPGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWELVPGHNRTWANY SECVKFLTNETREREVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHLF LSFMLRAVSIFVKDAVLYSGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAVTF FLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAVFVAVWVSVRATLA NTGCWDLSSGNKKWIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRKLL KSTLVLMPLFGVHYIVFMATPYTEVSGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGEVQ AEIKKSWSRWTLALDFKRKARSGSSSYSYGPMVSHTSVTNVGPRVGLGLPLSPRLLPTAT TNGHPQLPGHAKPGTPALETLETTPPAMAAPKDDGFLNGSCSGLDEEASGPERPPALLQE EWETVM |