| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 5328 |
Name | PLAU |
Synonym | ATF|BDPLT5|QPD|UPA|URK|u-PA;plasminogen activator, urokinase;PLAU;plasminogen activator, urokinase |
Definition | U-plasminogen activator|plasminogen activator, urinary|urokinase-type plasminogen activator |
Position | 10q22.2 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | E2F transcription factor network;PID Curated;200027 |
Pathway | Validated transcriptional targets of AP1 family members Fra1 and Fra2;PID Curated;200044 |
Pathway | Hemostasis;Reactome;REACT:604 |
Pathway | Dissolution of Fibrin Clot;PID Reactome;500304 |
Pathway | Osteopontin-mediated events;PID Curated;200042 |
Pathway | Complement and coagulation cascades;KEGG PATHWAY;hsa04610 |
Pathway | fibrinolysis pathway;PID BioCarta;100164 |
Pathway | Blood coagulation;PANTHER;P00011 |
Pathway | AP-1 transcription factor network;PID Curated;200118 |
Pathway | platelet amyloid precursor protein pathway;PID BioCarta;100072 |
Pathway | ATF-2 transcription factor network;PID Curated;200116 |
Pathway | amb2 Integrin signaling;PID Curated;200108 |
Pathway | Plasminogen activating cascade;PANTHER;P00050 |
Pathway | FGF signaling pathway;PID Curated;200189 |
Disease | Alzheimer disease, late-onset, susceptibility to;OMIM |
Disease | Alzheimer's disease;GAD |
Disease | Asthma;FunDO |
Disease | Cancer;FunDO |
Disease | Polyarthritis;FunDO |
Disease | Oral cancer;FunDO |
Disease | bladder cancer;GAD |
Disease | Mitral valve disease;FunDO |
Disease | oral cancer;GAD |
Disease | Dermatitis;FunDO |
Disease | Prostate cancer;FunDO |
Disease | Cystic fibrosis;FunDO |
Disease | IMMUNE;GAD |
Disease | Systemic scleroderma;FunDO |
Disease | Rheumatoid arthritis;FunDO |
Disease | Peptic ulcer;FunDO |
Disease | METABOLIC;GAD |
Disease | rheumatoid arthritis;GAD |
Disease | Alzheimer's disease;FunDO |
Disease | colorectal cancer;GAD |
Disease | Periodontal disease;FunDO |
Disease | bone density;GAD |
Disease | Hamman-Rich syndrome;FunDO |
Disease | CARDIOVASCULAR;GAD |
Disease | Late pregnancy;FunDO |
Disease | CANCER;GAD |
Disease | Endometriosis;FunDO |
Disease | Chronic obstructive airway disease;FunDO |
Disease | NEUROLOGICAL;GAD |
Disease | mitral valve prolapse;GAD |
Disease | urolithiasis;GAD |
Disease | late-onset Alzheimer's disease;GAD |
Disease | Atherosclerosis;FunDO |
External Links | |
Links to Entrez Gene | 5328 |
Links to all GeneRIF Items | 5328 |
Links to iHOP | 5328 |
Sequence Information | |
Nucleotide Sequence | >5328 : length: 2680 ATATAGAGCAGGCGCCGCGGGTCGCAGCACAGTGCGGAGACCGCAGCCCCGGAGCCCGGG CCAGGGTCCACCTGTCCCCGCAGCGCCGGCTCGCGCCCTCCTGCCGCAGCCACCGAGCCG CCGTCTAGCGCCCCGACCTCGCCACCATGAGAGCCCTGCTGGCGCGCCTGCTTCTCTGCG TCCTGGTCGTGAGCGACTCCAAAGTGAGTGCGCTCTTGCTTTGACTGATGCTGCCCAAGG ACCTCTGATCAGCACCAGGGGAGAGGAGGGGCTGCTCAGGGAGCTGGGGTCCTCCGGATT CCATCCACAGCAGGGCCAGACTCTCCCCAGGAAATGGGACAGGGTGGCAGCGGAGGCTTG AGAACCACGGGGGTTGGCACTGGCTGGCAAGGGAGGAAGAGGCCGCCGGGACTGCCCCAG CCTGCGGGCATCTGGTAGATGAAGCTTGCTTGGGTCAATCCATTTCTCCTGGCTGGAAAC CCATGGTCTTCCATTTGAGAACTAGATACGAACAGGCGAACTGTGACTGTCTAAATGGAG GAACATGTGTGTCCAACAAGTACTTCTCCAACATTCACTGGTGCAACTGCCCAAAGAAAT TCGGAGGGCAGCACTGTGAAATAGATAAGTCAAAAACCTGCTATGAGGGGAATGGTCACT TTTACCGAGGAAAGGCCAGCACTGACACCATGGGCCGGCCCTGCCTGCCCTGGAACTCTG CCACTGTCCTTCAGCAAACGTACCATGCCCACAGATCTGATGCTCTTCAGCTGGGCCTGG GGAAACATAATTACTGCAGGAACCCAGACAACCGGAGGCGACCCTGGTGCTATGTGCAGG TGGGCCTAAAGCCGCTTGTCCAAGAGTGCATGGTGCATGACTGCGCAGATGGAAAAAAGC CCTCCTCTCCTCCAGAAGAATTAAAATTTCAGTGTGGCCAAAAGACTCTGAGGCCCCGCT TTAAGATTATTGGGGGAGAATTCACCACCATCGAGAACCAGCCCTGGTTTGCGGCCATCT ACAGGAGGCACCGGGGGGGCTCTGTCACCTACGTGTGTGGAGGCAGCCTCATCAGCCCTT GCTGGGTGATCAGCGCCACACACTGCTTCATTGATTACCCAAAGAAGGAGGACTACATCG TCTACCTGGGTCGCTCAAGGCTTAACTCCAACACGCAAGGGGAGATGAAGTTTGAGGTGG AAAACCTCATCCTACACAAGGACTACAGCGCTGACACGCTTGCTCACCACAACGACATTG CCTTGCTGAAGATCCGTTCCAAGGAGGGCAGGTGTGCGCAGCCATCCCGGACTATACAGA CCATCTGCCTGCCCTCGATGTATAACGATCCCCAGTTTGGCACAAGCTGTGAGATCACTG GCTTTGGAAAAGAGAATTCTACCGACTATCTCTATCCGGAGCAGCTGAAAATGACTGTTG TGAAGCTGATTTCCCACCGGGAGTGTCAGCAGCCCCACTACTACGGCTCTGAAGTCACCA CCAAAATGCTGTGTGCTGCTGACCCACAGTGGAAAACAGATTCCTGCCAGGGAGACTCAG GGGGACCCCTCGTCTGTTCCCTCCAAGGCCGCATGACTTTGACTGGAATTGTGAGCTGGG GCCGTGGATGTGCCCTGAAGGACAAGCCAGGCGTCTACACGAGAGTCTCACACTTCTTAC CCTGGATCCGCAGTCACACCAAGGAAGAGAATGGCCTGGCCCTCTGAGGGTCCCCAGGGA GGAAACGGGCACCACCCGCTTTCTTGCTGGTTGTCATTTTTGCAGTAGAGTCATCTCCAT CAGCTGTAAGAAGAGACTGGGAAGATAGGCTCTGCACAGATGGATTTGCCTGTGCCACCC ACCAGGGCGAACGACAATAGCTTTACCCTCAGGCATAGGCCTGGGTGCTGGCTGCCCAGA CCCCTCTGGCCAGGATGGAGGGGTGGTCCTGACTCAACATGTTACTGACCAGCAACTTGT CTTTTTCTGGACTGAAGCCTGCAGGAGTTAAAAAGGGCAGGGCATCTCCTGTGCATGGGT GAAGGGAGAGCCAGCTCCCCCGACGGTGGGCATTTGTGAGGCCCATGGTTGAGAAATGAA TAATTTCCCAATTAGGAAGTGTAACAGCTGAGGTCTCTTGAGGGAGCTTAGCCAATGTGG GAGCAGCGGTTTGGGGAGCAGAGACACTAACGACTTCAGGGCAGGGCTCTGATATTCCAT GAATGTATCAGGAAATATATATGTGTGTGTATGTTTGCACACTTGTGTGTGGGCTGTGAG TGTAAGTGTGAGTAAGAGCTGGTGTCTGATTGTTAAGTCTAAATATTTCCTTAAACTGTG TGGACTGTGATGCCACACAGAGTGGTCTTTCTGGAGAGGTTATAGGTCACTCCTGGGGCC TCTTGGGTCCCCCACGTGACAGTGCCTGGGAATGTATTATTCTGCAGCATGACCTGTGAC CAGCACTGTCTCAGTTTCACTTTCACATAGATGTCCCTTTCTTGGCCAGTTATCCCTTCC TTTTAGCCTAGTTCATCCAATCCTCACTGGGTGGGGTGAGGACCACTCCTGTACACTGAA TATTTATATTTCACTATTTTTATTTATATTTTTGTAATTTTAAATAAAAGTGATCAATAA AATGTGATTTTTCTGATGACAAAAAAAAAAAAAAAAAAAA |
Protein Sequence | >5328 : length: 431 MRALLARLLLCVLVVSDSKGSNELHQVPSNCDCLNGGTCVSNKYFSNIHWCNCPKKFGGQ HCEIDKSKTCYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHN YCRNPDNRRRPWCYVQVGLKLLVQECMVHDCADGKKPSSPPEELKFQCGQKTLRPRFKII GGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLG RSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTICL PSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKML CAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIR SHTKEENGLAL |