| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 4803 |
Name | NGF |
Synonym | Beta-NGF|HSAN5|NGFB;nerve growth factor (beta polypeptide);NGF;nerve growth factor (beta polypeptide) |
Definition | beta-nerve growth factor|nerve growth factor, beta subunit |
Position | 1p13.1 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | nerve growth factor pathway (ngf);PID BioCarta;100096 |
Pathway | trka receptor signaling pathway;PID BioCarta;100011 |
Pathway | Trk receptor signaling mediated by PI3K and PLC-gamma;PID Curated;200183 |
Pathway | p75(NTR)-mediated signaling;PID Curated;200103 |
Pathway | Apoptosis;KEGG PATHWAY;hsa04210 |
Pathway | TRKA activation by NGF;PID Reactome;500623 |
Pathway | Neurotrophin signaling pathway;KEGG PATHWAY;hsa04722 |
Pathway | MAPK signaling pathway;KEGG PATHWAY;hsa04010 |
Pathway | Neurotrophic factor-mediated Trk receptor signaling;PID Curated;200128 |
Pathway | NFG and proNGF binds to p75NTR;PID Reactome;500607 |
Pathway | Axonal growth stimulation;PID Reactome;500618 |
Pathway | NGF processing;PID Reactome;500605 |
Pathway | phosphorylation of mek1 by cdk5/p35 down regulates the map kinase pathway;PID BioCarta;100210 |
Pathway | Signalling by NGF;Reactome;REACT:11061 |
Pathway | role of erk5 in neuronal survival pathway;PID BioCarta;100171 |
Pathway | erk1/erk2 mapk signaling pathway;PID BioCarta;100170 |
Disease | Neuropathy, hereditary sensory and autonomic, type V;OMIM |
External Links | |
Links to Entrez Gene | 4803 |
Links to all GeneRIF Items | 4803 |
Links to iHOP | 4803 |
Sequence Information | |
Nucleotide Sequence | >4803 : length: 1263 GGAAATGTCACTGCAGAAGAGCAAGGGAGCTCAAGACGCGATGGCAGCTGTCACTCCAGA GTGGTGTGGAGTGGGACGGTATCTGATGTGTCCTCAGATTCGGTTTCCCTTGGGATGTGT TTGGTGCTGACTGCTTGTGATCCATGTTTTCTTGGATGCAGGTTGGTAGAGGTGCAGCAA TTTTTGCAGTGAAACTGAAGTCCAGCTGCTCAAACAGAAATGGCCTCATCTAATGGACAC TTTAATGAAGTTTTGGCCAGTGGTCGTGCAGTCCAAGGGGCTGGATGGCATGCTGGACCC AAGCTCAGCTCAGCGTCCGGACCCAATAACAGTTTTACCAAGGGAGCAGCTTTCTATCCT GGCCACACTGAGGTGCATAGCGTAATGTCCATGTTGTTCTACACTCTGATCACAGCTTTT CTGATCGGCATACAGGCGGAACCACACTCAGAGAGCAATGTCCCTGCAGGACACACCATC CCCCAAGCCCACTGGACTAAACTTCAGCATTCCCTTGACACTGCCCTTCGCAGAGCCCGC AGCGCCCCGGCAGCGGCGATAGCTGCACGCGTGGCGGGGCAGACCCGCAACATTACTGTG GACCCCAGGCTGTTTAAAAAGCGGCGACTCCGTTCACCCCGTGTGCTGTTTAGCACCCAG CCTCCCCGTGAAGCTGCAGACACTCAGGATCTGGACTTCGAGGTCGGTGGTGCTGCCCCC TTCAACAGGACTCACAGGAGCAAGCGGTCATCATCCCATCCCATCTTCCACAGGGGCGAA TTCTCGGTGTGTGACAGTGTCAGCGTGTGGGTTGGGGATAAGACCACCGCCACAGACATC AAGGGCAAGGAGGTGATGGTGTTGGGAGAGGTGAACATTAACAACAGTGTATTCAAACAG TACTTTTTTGAGACCAAGTGCCGGGACCCAAATCCCGTTGACAGCGGGTGCCGGGGCATT GACTCAAAGCACTGGAACTCATATTGTACCACGACTCACACCTTTGTCAAGGCGCTGACC ATGGATGGCAAGCAGGCTGCCTGGCGGTTTATCCGGATAGATACGGCCTGTGTGTGTGTG CTCAGCAGGAAGGCTGTGAGAAGAGCCTGACCTGCCGACACGCTCCCTCCCCCTGCCCCT TCTACACTCTCCTGGGCCCCTCCCTACCTCAACCTGTAAATTATTTTAAATTATAAGGAC TGCATGGTAATTTATAGTTTATACAGTTTTAAAGAATCATTATTTATTAAATTTTTGGAA GCA |
Protein Sequence | >4803 : length: 296 MASSNGHFNEVLASGRAVQGAGWHAGPKLSSASGPNNSFTKGAAFYPGHTEVHSVMSMLF YTLITAFLIGIQAEPHSESNVPAGHTIPQAHWTKLQHSLDTALRRARSAPAAAIAARVAG QTRNITVDPRLFKKRRLRSPRVLFSTQPPREAADTQDLDFEVGGAAPFNRTHRSKRSSSH PIFHRGEFSVCDSVSVWVGDKTTATDIKGKEVMVLGEVNINNSVFKQYFFETKCRDPNPV DSGCRGIDSKHWNSYCTTTHTFVKALTMDGKQAAWRFIRIDTACVCVLSRKAVRRA |