| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 405 |
Name | ARNT |
Synonym | HIF-1-beta|HIF-1beta|HIF1-beta|HIF1B|HIF1BETA|TANGO|bHLHe2;aryl hydrocarbon receptor nuclear translocator;ARNT;aryl hydrocarbon receptor nuclear translocator |
Definition | class E basic helix-loop-helix protein 2|dioxin receptor, nuclear translocator|hypoxia-inducible factor 1, beta subunit |
Position | 1q21 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Signaling events mediated by VEGFR1 and VEGFR2;PID Curated;200161 |
Pathway | Hypoxia response via HIF activation;PANTHER;P00030 |
Pathway | ahr signal transduction pathway;PID BioCarta;100251 |
Pathway | hypoxia-inducible factor in the cardivascular system;PID BioCarta;100145 |
Pathway | vegf hypoxia and angiogenesis;PID BioCarta;100006 |
Pathway | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha;PID Curated;200122 |
Pathway | Notch-mediated HES/HEY network;PID Curated;200196 |
Pathway | HIF-2-alpha transcription factor network;PID Curated;200030 |
Pathway | HIF-1-alpha transcription factor network;PID Curated;200172 |
Pathway | Pathways in cancer;KEGG PATHWAY;hsa05200 |
Pathway | Renal cell carcinoma;KEGG PATHWAY;hsa05211 |
Disease | micropenis;GAD |
Disease | Leukemia, acute myeloblastic;OMIM |
Disease | Diabetes mellitus;FunDO |
Disease | Leukemia;FunDO |
Disease | Uterine fibroids;FunDO |
Disease | Infertility;FunDO |
Disease | Endometriosis;FunDO |
Disease | Breast cancer;FunDO |
External Links | |
Links to Entrez Gene | 405 |
Links to all GeneRIF Items | 405 |
Links to iHOP | 405 |
Sequence Information | |
Nucleotide Sequence | >405 : length: 4944 ATATAGGCGGGGTCTCCCCGCCGCAGGGGCTGGGATGCTGGGGGCTGCTGAAGCCGCCAT CTTGGATTCCGCGGTAGCGGAGGCGGCGGTCAGGCGCCGCTTCTGGGGAGTGGCCTTTCT TTTCCCCTCCCTCCCGGTTCGGTGGCGGCGGCTCCTCCCACTGGGGGGGGGGGTGGCGCG GCGGCGGTGGCATCTGCGGCCATGGCGGCGACTACTGCCAACCCCGCCTGATCTTGGACT CAAGATTCTCCTGCCTCAGACCCCGAGTAGCTGGGACTACAGAAATGACATCAGATGTAC CATCACTGGGTCCAGCCATTGCCTCTGGAAACTCTGGACCTGGAATTCAAGGTGGAGGAG CCATTGTCCAGAGGGCTATTAAGCGGCGACCAGGGCTGGATTTTGATGATGATGGAGAAG GGAACAGTAAATTTTTGAGGTGTGATGATGATCAGATGTCTAACGATAAGGAGCGGTTTG CCAGGTCGGATGATGAGCAGAGCTCTGCGGATAAAGAGAGACTTGCCAGGGAAAATCACA GTGAAATTGAACGGCGGCGACGGAACAAGATGACAGCCTACATCACAGAACTGTCAGATA TGGTACCCACCTGTAGTGCCCTGGCTCGAAAACCAGACAAGCTAACCATCTTACGCATGG CAGTTTCTCACATGAAGTCCTTGCGGGGAACTGGCAACACATCCACTGATGGCTCCTATA AGCCGTCTTTCCTCACTGATCAGGAACTGAAACATTTGATCTTGGAGGCAGCAGATGGCT TTCTGTTTATTGTCTCATGTGAGACAGGCAGGGTGGTGTATGTGTCTGACTCCGTGACTC CTGTTTTGAACCAGCCACAGTCTGAATGGTTTGGCAGCACACTCTATGATCAGGTGCACC CAGATGATGTGGATAAACTTCGTGAGCAGCTTTCCACTTCAGAAAATGCCCTGACAGGGC GTATCCTGGATCTAAAGACTGGAACAGTGAAAAAGGAAGGTCAGCAGTCTTCCATGAGAA TGTGTATGGGCTCAAGGAGATCGTTTATTTGCCGAATGAGGTGTGGCAGTAGCTCTGTGG ACCCAGTTTCTGTGAATAGGCTGAGCTTTGTGAGGAACAGATGCAGGAATGGACTTGGCT CTGTAAAGGATGGGGAACCTCACTTCGTGGTGGTCCACTGCACAGGCTACATCAAGGCCT GGCCCCCAGCAGATGATGACCCAGAGGCTGGCCAGGGAAGCAAGTTTTGCCTAGTGGCCA TTGGCAGATTGCAGGTAACTAGTTCTCCCAACTGTACAGACATGAGTAATGTTTGTCAAC CAACAGAGTTCATCTCCCGACACAACATTGAGGGTATCTTCACTTTTGTGGATCACCGCT GTGTGGCTACTGTTGGCTACCAGCCACAGGAACTCTTAGGAAAGAATATTGTAGAATTCT GTCATCCTGAAGACCAGCAGCTTCTAAGAGACAGCTTCCAACAGGTAGTGAAATTAAAAG GCCAAGTGCTGTCTGTCATGTTCCGGTTCCGGTCTAAGAACCAAGAATGGCTCTGGATGA GAACCAGCTCCTTTACTTTCCAGAACCCTTACTCAGATGAAATTGAGTACATCATCTGTA CCAACACCAATGTGAAGAACTCTAGCCAAGAACCACGGCCTACACTCTCCAACACAATCC AGAGGCCACAACTAGGTCCCACAGCTAATTTACCCCTGGAGATGGGCTCAGGACAGCTGG CACCCAGGCAGCAGCAACAGCAAACAGAATTGGACATGGTACCAGGAAGAGATGGACTGG CCAGCTACAATCATTCCCAGGTGGTTCAGCCTGTGACAACCACAGGACCAGAACACAGCA AGCCCCTTGAGAAGTCAGATGGTTTATTTGCCCAGGATAGAGATCCAAGATTTTCAGAAA TCTATCACAACATCAATGCGGATCAGAGTAAAGGCATCTCCTCCAGCACTGTCCCTGCCA CCCAACAGCTATTCTCCCAGGGCAACACATTCCCTCCTACCCCCCGGCCGGCAGAGAATT TCAGGAATAGTGGCCTAGCCCCTCCTGTAACCATTGTCCAGCCATCAGCTTCTGCAGGAC AGATGTTGGCCCAGATTTCCCGCCACTCCAACCCCACCCAAGGAGCAACCCCAACTTGGA CCCCTACTACCCGCTCAGGCTTTTCTGCCCAGCAGGTGGCTACCCAGGCTACTGCTAAGA CTCGTACTTCCCAGTTTGGTGTGGGCAGCTTTCAGACTCCATCCTCCTTCAGCTCCATGT CCCTCCCTGGTGCCCCAACTGCATCGCCTGGTGCTGCTGCCTACCCTAGTCTCACCAATC GTGGATCTAACTTTGCTCCTGAGACTGGACAGACTGCAGGACAATTCCAGACACGGACAG CAGAGGGTGTGGGTGTCTGGCCACAGTGGCAGGGCCAGCAGCCTCATCATCGTTCAAGTT CTAGTGAGCAACATGTTCAACAACCGCCAGCACAGCAACCTGGCCAGCCTGAGGTCTTCC AGGAGATGCTGTCCATGCTGGGAGATCAGAGCAACAGCTACAACAATGAAGAATTCCCTG ATCTAACTATGTTTCCCCCCTTTTCAGAATAGAACTATTGGGGTGAGGATAAGGGGTGGG GGAGAAAAAATCACTGTTTGTTTTTAAAAAGCAAATCTTTCTGTAAACAGAATAAAAGTT CCTCTCCCTTCCCTTCCCTCACCCCTGACATGTACCCCCTTTCCCTTCTGGCTGTTCCCC TGCTCTGTTGCCTCTCTAAGGTAACATTTATAGAAGAAATGGAATGAATCTCCAAGGCTT TTAGGACTGTCTGAAAATTTGAGGCTGGGTGAAGTTAAAACACCTTTCCTTATGTCTCCT GACCTGAAATTGTATAGTGTTGATTTGTGCTGAGATCAAGAGGCAGGTTAGAAGAACCTG ACATCCACTGTTTGCCTTGGATAGTATGGCTTGTTTTTGGAAAGAAATTCTGAAGAGAGT GGAGGAGAGGAGAAATGTCCTCATATTTGAGGACCATGAAACATTGTAGGTATATATGGG GCTTTAGCAAGTTTGAGCATAGGCTCTTTTTGCTGCCTGTGAGCAGTCCCTCTGGAAAGA AACATGTGAGTAAGTGAGAGAGAGTGTGTGTGTATGTGTGTGTGTGTGTGTGTGCGCACA CATGCTTCTGTATTTCACTCTTTCTCCCTATTAGGGAGTTATGCAAAATTTGTCCCCGAT TTTACCTTTGTCTTTCTGTGTACTTTTCAAAGAGTCCTAAGGAGTTAAATCTTCCAGGTA TTTTCCACTTAGTATTGCAGCCAAAGAATATTTAAATAAACGTCTTTGCTGCGCTTGCAT CCATGCCCAGCCAATATACAACTGTAAAGCAAATATAGAAAGTCGGCTGTTGATACGATT GTCTGTTATCGAACACATTCAGTGATAAAGCTGGGTTACTGCTGCTTTTGGTGCTCTCAC CTTATCTGGAAGATCTGCAAACATTACCTAAATAGGCTGGCAAGATAAACACTTTCTGGA ACCCGAGACTTGGCCATAAAGATAATGCTGCATTTTTCTGTCAGAATCACATATGATGTG TGTTCTGTAGAGGTTATTTCTGCATGGAAACTCAACTTCTTGGATTAGCCGTCCCAGTGA AAATCCTCATTGTTGGAGTGTAAACCAAATACGAAGCCCTCTTGCAAAGTAGCCTCTTTC ATCCCATACTCAAAATACCCAGTTTAGCAAGCAACTGAGATTTAAGTCTCTCTGGCCCTA AGAGGTTTTTCCTCTTTGCTCCCTCCAATCTTGAGATTGGGTTTTGCTTTAGAGTGCAAG TATCATAATTCCGTATGATAGATGGGGCCTGGACACCCATCTCAACAGGGTCACTTGGTA ATTAACAATAGCCATATAAATGCGGATACAGGTTACTACCCTCACCCTTTACCTTCCTCA GGTAACAGTCGTAGATACCAGCTTTTTTTTTTTTTTTTTTAAATTGGCTTTGGCCAGTAG CTAAAGTGCAAGACTGAATTAATGAGAAGATATATTAAATGTAGTCATAGGGGACTGAGG AGCAAGGGTGGCCTTGAAGAGGCCAAAGGAATGTCCATTTGCTGAGTTTCCCTTCCTTAT GTCTCCAGTCTGGTGCCAGGTAGTGGAGTAAAAAAGGAGACAGTTTATTTTTTTATTCTA TGTGCACACTTACAGTATACATATATATTTATATCACAATTTACGAAACCAAAAAGTTGA GTTTCCAATGGAACCCTTGTTTTTTAATAATCGACTTTTTAAATGTGATCAGGACTATAA TATTGTACAGTTATTATAGGGCTTTTGGGGAAGGGGAGGATAGCGAGAAGATGCTCTGGG GGTTTTGTTTTTGCTTTTCCTTCAGGGTTTTATTTTTGACTGTTTTGTTTTCTTGTTGGC CATTTCTGTATTGCTGGCATCTGTGCTAAGCTTTACAGTGGCAAAAATAATGACATGTAG CAAAGATTTTCAAACAAAATATTTTTTCCTTTTGTAAAATTTCTTGTGTTGTGTGATCTT GATTGCGGCTTTATCATTCCTTTCCAGTTCATAAACAACAGGCACCCACAACCAGAGGAA TCTATAGTTTAAGCTCCAGACATACAAACATAAGGCACATTGTGTCTTTAATTTCAGGAA TCAGAAATCATAGGGTTCTGATCACATTGCACGCCTCCCCCCTCACTTGTCCTCCTGATC CTGACACATTCTGAGTAACATCAGCAGGAATGCTCTGACCATGAGGTGGGGGTTTTGGGG TGGGCGTTGCCTGGGTTCTTGGGAGAGAGGGGAAGAGTCGGGACTTGAAAACCACTAGGG CACATCTGGATGCCTTCCCCCAGTATGTCCTTTTCTGGATTAAAATGAGTGAAATTTAAA CTGTTCAAAAAAAAAAAAAAAAAA |
Protein Sequence | >405 : length: 789 MAATTANPEMTSDVPSLGPAIASGNSGPGIQGGGAIVQRAIKRRPGLDFDDDGEGNSKFL RCDDDQMSNDKERFARSDDEQSSADKERLARENHSEIERRRRNKMTAYITELSDMVPTCS ALARKPDKLTILRMAVSHMKSLRGTGNTSTDGSYKPSFLTDQELKHLILEAADGFLFIVS CETGRVVYVSDSVTPVLNQPQSEWFGSTLYDQVHPDDVDKLREQLSTSENALTGRILDLK TGTVKKEGQQSSMRMCMGSRRSFICRMRCGSSSVDPVSVNRLSFVRNRCRNGLGSVKDGE PHFVVVHCTGYIKAWPPAGVSLPDDDPEAGQGSKFCLVAIGRLQVTSSPNCTDMSNVCQP TEFISRHNIEGIFTFVDHRCVATVGYQPQELLGKNIVEFCHPEDQQLLRDSFQQVVKLKG QVLSVMFRFRSKNQEWLWMRTSSFTFQNPYSDEIEYIICTNTNVKNSSQEPRPTLSNTIQ RPQLGPTANLPLEMGSGQLAPRQQQQQTELDMVPGRDGLASYNHSQVVQPVTTTGPEHSK PLEKSDGLFAQDRDPRFSEIYHNINADQSKGISSSTVPATQQLFSQGNTFPPTPRPAENF RNSGLAPPVTIVQPSASAGQMLAQISRHSNPTQGATPTWTPTTRSGFSAQQVATQATAKT RTSQFGVGSFQTPSSFSSMSLPGAPTASPGAAAYPSLTNRGSNFAPETGQTAGQFQTRTA EGVGVWPQWQGQQPHHRSSSSEQHVQQPPAQQPGQPEVFQEMLSMLGDQSNSYNNEEFPD LTMFPPFSE |