| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 3827 |
Name | KNG1 |
Synonym | BDK|BK|KNG;kininogen 1;KNG1;kininogen 1 |
Definition | HMWK|alpha-2-thiol proteinase inhibitor|bradykinin|fitzgerald factor|high molecular weight kininogen|kininogen-1|williams-Fitzgerald-Flaujeac factor |
Position | 3q27 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Peptide ligand-binding receptors;PID Reactome;500405 |
Pathway | Signaling by GPCR;Reactome;REACT:14797 |
Pathway | Hemostasis;Reactome;REACT:604 |
Pathway | intrinsic prothrombin activation pathway;PID BioCarta;100122 |
Pathway | Intrinsic Pathway;PID Reactome;500302 |
Pathway | Complement and coagulation cascades;KEGG PATHWAY;hsa04610 |
Pathway | Blood coagulation;PANTHER;P00011 |
Pathway | Syndecan-2-mediated signaling events;PID Curated;200164 |
Pathway | actions of nitric oxide in the heart;PID BioCarta;100094 |
Disease | Kininogen deficiency;OMIM |
Disease | Adenocarcinoma;FunDO |
Disease | Adiponectin levels;NHGRI |
Disease | Hypertension;FunDO |
Disease | Systemic infection;FunDO |
Disease | Activated partial thromboplastin time;NHGRI |
Disease | High molecular weight kininogen deficiency;OMIM |
Disease | Neoplasm metastasis;FunDO |
External Links | |
Links to Entrez Gene | 3827 |
Links to all GeneRIF Items | 3827 |
Links to iHOP | 3827 |
Sequence Information | |
Nucleotide Sequence | >3827 : length: 2732 AGTGTTGCAATGTTCTAGCTGTAAATATGTTTGGATAACCCAGCAGAGCCATTTAACCTT TGGGAACAAGGCAACTAGCGTCTGGCAGCAGGAATCCAACCAGTGCCCTGAGTTCTGAGG CAGAGAGGAGGACAGAAGAAACAAGAGGCTGGAGATTGTCAAATTCAGTATCCCAGTTGG CTCTTGATTCTTGGTGAAACCATCCCTCAGCTCCTAGAGGGAGATTGTTAGATCATGAAA CTAATTACCATCCTTTTCCTCTGCTCCAGGCTGCTACTAAGTTTAACCCAGGAATCACAG TCCGAGGAAATTGACTGCAATGACAAGGATTTATTTAAAGCTGTGGATGCTGCTCTGAAG AAATATAACAGTCAAAACCAAAGTAACAACCAGTTTGTATTGTACCGCATAACTGAAGCC ACTAAGACGGTTGGCTCTGACACGTTTTATTCCTTCAAGTACGAAATCAAGGAGGGGGAT TGTCCTGTTCAAAGTGGCAAAACCTGGCAGGACTGTGAGTACAAGGATGCTGCAAAAGCA GCCACTGGAGAATGCACGGCAACCGTGGGGAAGAGGAGCAGTACGAAATTCTCCGTGGCT ACCCAGACCTGCCAGATTACTCCAGCCGAGGGCCCTGTGGTGACAGCCCAGTACGACTGC CTCGGCTGTGTGCATCCTATATCAACGCAGAGCCCAGACCTGGAGCCCATTCTGAGACAC GGCATTCAGTACTTTAACAACAACACTCAACATTCCTCCCTCTTCATGCTTAATGAAGTA AAACGGGCCCAAAGACAGGTGGTGGCTGGATTGAACTTTCGAATTACCTACTCAATTGTG CAAACGAATTGTTCCAAAGAGAATTTTCTGTTCTTAACTCCAGACTGCAAGTCCCTTTGG AATGGTGATACCGGTGAATGTACAGATAATGCATACATCGATATTCAGCTACGAATTGCT TCCTTCTCACAGAACTGTGACATTTATCCAGGGAAGGATTTTGTACAACCACCTACCAAG ATTTGCGTGGGCTGCCCCAGAGATATACCCACCAACAGCCCAGAGCTGGAGGAGACACTG ACTCACACCATCACAAAGCTTAATGCAGAGAATAACGCAACTTTCTATTTCAAGATTGAC AATGTGAAAAAAGCAAGAGTACAGGTGGTGGCTGGCAAGAAATATTTTATTGACTTCGTG GCCAGGGAAACCACATGTTCCAAGGAAAGTAATGAAGAGTTGACCGAAAGCTGTGAGACC AAAAAACTTGGCCAAAGCCTAGATTGCAACGCTGAAGTTTATGTGGTACCCTGGGAGAAA AAAATTTACCCTACTGTCAACTGTCAACCACTGGGAATGATCTCACTGATGAAAAGGCCT CCAGGTTTTTCACCTTTCCGATCATCACGAATAGGGGAAATAAAAGAAGAAACAACTGTA AGTCCACCCCACACTTCCATGGCACCTGCACAAGATGAAGAGCGGGATTCAGGAAAAGAA CAAGGGCATACTCGTAGACATGACTGGGGCCATGAAAAACAAAGAAAACATAATCTTGGC CATGGCCATAAACATGAACGTGACCAAGGGCATGGGCACCAAAGAGGACATGGCCTTGGC CATGGACACGAACAACAGCATGGTCTTGGTCATGGACATAAGTTCAAACTTGATGATGAT CTTGAACACCAAGGGGGCCATGTCCTTGACCATGGACATAAGCATAAGCATGGTCATGGC CACGGAAAACATAAAAATAAAGGCAAAAAGAATGGAAAGCACAATGGTTGGAAAACAGAG CATTTGGCAAGCTCTTCTGAAGACAGTACTACACCTTCTGCACAGACACAAGAGAAGACA GAAGGGCCAACACCCATCCCTTCCCTAGCCAAGCCAGGTGTAACAGTTACCTTTTCTGAC TTTCAGGACTCTGATCTCATTGCAACTATGATGCCTCCTATATCACCAGCTCCCATACAG AGTGATGACGATTGGATCCCTGATATCCAGATAGACCCAAATGGCCTTTCATTTAACCCA ATATCAGATTTTCCAGACACGACCTCCCCAAAATGTCCTGGACGCCCCTGGAAGTCAGTT AGTGAAATTAATCCAACCACACAAATGAAAGAATCTTATTATTTCGATCTCACTGATGGC CTTTCTTAATTTAAGTGGCTATGGGTATTTCTTTCATACTTTATTAAAGTATCAATATCC CTCTCTCCATTGTCCAGATGAAAATATCCTGATATAATGCACCAAAAACCATGCAGCTTC GGAACAGTCTAAAGAGAAGTGGTGAGACTCCCAGTGGAGACACCATCAGTCTCCACGGAC TGCATAAAATTGTGTGCCACAATTCTAACTCTTTTCTGAATCTTCTTCCCAAGTTTTCTA AACTAGCACAGTAAACAGACAAACTAATGTGCCGTATGGCCTGCTGCAATTGGCTTCTCT GATAACAAATATGTACCTTACAACATATGTCATGAATTTGCATACAAAGATTCTTGTCAT TCTTAATAAACTGTGGCACTTGGTATTTGAATGTGTGTGAAAATAAGGGAAGTCAAGAGA TTAAATGCTGAACTTATTAATGGAATAGAAATAATAAGGAGGCTGAGGCTGGAGAATTGC TTGAACCCGGGAGGCGGAGGTTGCAGTGAGCCGAGATCGTGCCACTGCGCTCCAGCCTGG GCATCAGAGCAAGATTCTGTCTCAGAAAAAAA |
Protein Sequence | >3827 : length: 644 MKLITILFLCSRLLLSLTQESQSEEIDCNDKDLFKAVDAALKKYNSQNQSNNQFVLYRIT EATKTVGSDTFYSFKYEIKEGDCPVQSGKTWQDCEYKDAAKAATGECTATVGKRSSTKFS VATQTCQITPAEGPVVTAQYDCLGCVHPISTQSPDLEPILRHGIQYFNNNTQHSSLFMLN EVKRAQRQVVAGLNFRITYSIVQTNCSKENFLFLTPDCKSLWNGDTGECTDNAYIDIQLR IASFSQNCDIYPGKDFVQPPTKICVGCPRDIPTNSPELEETLTHTITKLNAENNATFYFK IDNVKKARVQVVAGKKYFIDFVARETTCSKESNEELTESCETKKLGQSLDCNAEVYVVPW EKKIYPTVNCQPLGMISLMKRPPGFSPFRSSRIGEIKEETTVSPPHTSMAPAQDEERDSG KEQGHTRRHDWGHEKQRKHNLGHGHKHERDQGHGHQRGHGLGHGHEQQHGLGHGHKFKLD DDLEHQGGHVLDHGHKHKHGHGHGKHKNKGKKNGKHNGWKTEHLASSSEDSTTPSAQTQE KTEGPTPIPSLAKPGVTVTFSDFQDSDLIATMMPPISPAPIQSDDDWIPDIQIDPNGLSF NPISDFPDTTSPKCPGRPWKSVSEINPTTQMKESYYFDLTDGLS |