| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 3577 |
Name | CXCR1 |
Synonym | C-C|C-C-CKR-1|CD128|CD181|CDw128a|CKR-1|CMKAR1|IL8R1|IL8RA|IL8RBA;chemokine (C-X-C motif) receptor 1;CXCR1;chemokine (C-X-C motif) receptor 1 |
Definition | C-X-C chemokine receptor type 1|CXC-R1|CXCR-1|IL-8 receptor type 1|IL-8R A|high affinity interleukin-8 receptor A|interleukin 8 receptor, alpha|interleukin-8 receptor type 1|interleukin-8 receptor type A |
Position | 2q35 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Endocytosis;KEGG PATHWAY;hsa04144 |
Pathway | Signaling by GPCR;Reactome;REACT:14797 |
Pathway | Cytokine-cytokine receptor interaction;KEGG PATHWAY;hsa04060 |
Pathway | Chemokine signaling pathway;KEGG PATHWAY;hsa04062 |
Pathway | Epithelial cell signaling in Helicobacter pylori infection;KEGG PATHWAY;hsa05120 |
Pathway | Interleukin signaling pathway;PANTHER;P00036 |
Pathway | Inflammation mediated by chemokine and cytokine signaling pathway;PANTHER;P00031 |
Pathway | Chemokine receptors bind chemokines;PID Reactome;500406 |
Disease | CANCER;GAD |
Disease | tuberculosis;GAD |
Disease | hematology indices;GAD |
Disease | Bronchiectasis;FunDO |
Disease | Infection;FunDO |
Disease | IMMUNE;GAD |
Disease | Hepatitis;FunDO |
Disease | Congenital abnormality;FunDO |
Disease | Arthritis;FunDO |
Disease | chronic obstructive pulmonary disease/COPD;GAD |
Disease | Leukemia;FunDO |
Disease | Melanoma;FunDO |
Disease | Waldenstrom macroglobulinaemia;GAD |
Disease | Asthma;GAD |
Disease | Polyarthritis;FunDO |
Disease | INFECTION;GAD |
Disease | Endometriosis;FunDO |
Disease | Colon cancer;FunDO |
Disease | Myeloid metaplasia;FunDO |
Disease | Myelofibrosis;FunDO |
Disease | Peptic esophagitis;FunDO |
External Links | |
Links to Entrez Gene | 3577 |
Links to all GeneRIF Items | 3577 |
Links to iHOP | 3577 |
Sequence Information | |
Nucleotide Sequence | >3577 : length: 2502 TATTCATCAAGTGCCCTCTAGCTGTTAAGTCACTCTGATCTCTGACTGCAGCTCCTACTG TTGGACACACCTGGCCGGTGCTTCAGTTAGATCAAACCATTGCTGAAACTGAAGAGGACA TGTCAAATATTACAGATCCACAGATGTGGGATTTTGATGATCTAAATTTCACTGGCATGC CACCTGCAGATGAAGATTACAGCCCCTGTATGCTAGAAACTGAGACACTCAACAAGTATG TTGTGATCATCGCCTATGCCCTAGTGTTCCTGCTGAGCCTGCTGGGAAACTCCCTGGTGA TGCTGGTCATCTTATACAGCAGGGTCGGCCGCTCCGTCACTGATGTCTACCTGCTGAACC TGGCCTTGGCCGACCTACTCTTTGCCCTGACCTTGCCCATCTGGGCCGCCTCCAAGGTGA ATGGCTGGATTTTTGGCACATTCCTGTGCAAGGTGGTCTCACTCCTGAAGGAAGTCAACT TCTACAGTGGCATCCTGCTGTTGGCCTGCATCAGTGTGGACCGTTACCTGGCCATTGTCC ATGCCACACGCACACTGACCCAGAAGCGTCACTTGGTCAAGTTTGTTTGTCTTGGCTGCT GGGGACTGTCTATGAATCTGTCCCTGCCCTTCTTCCTTTTCCGCCAGGCTTACCATCCAA ACAATTCCAGTCCAGTTTGCTATGAGGTCCTGGGAAATGACACAGCAAAATGGCGGATGG TGTTGCGGATCCTGCCTCACACCTTTGGCTTCATCGTGCCGCTGTTTGTCATGCTGTTCT GCTATGGATTCACCCTGCGTACACTGTTTAAGGCCCACATGGGGCAGAAGCACCGAGCCA TGAGGGTCATCTTTGCTGTCGTCCTCATCTTCCTGCTTTGCTGGCTGCCCTACAACCTGG TCCTGCTGGCAGACACCCTCATGAGGACCCAGGTGATCCAGGAGAGCTGTGAGCGCCGCA ACAACATCGGCCGGGCCCTGGATGCCACTGAGATTCTGGGATTTCTCCATAGCTGCCTCA ACCCCATCATCTACGCCTTCATCGGCCAAAATTTTCGCCATGGATTCCTCAAGATCCTGG CTATGCATGGCCTGGTCAGCAAGGAGTTCTTGGCACGTCATCGTGTTACCTCCTACACTT CTTCGTCTGTCAATGTCTCTTCCAACCTCTGAAAACCATCGATGAAGGAATATCTCTTCT CAGAAGGAAAGAATAACCAACACCCTGAGGTTGTGTGTGGAAGGTGATCTGGCTCTGGAC AGGCACTATCTGGGTTTTGGGGGGACGCTATAGGATGTGGGGAAGTTAGGAACTGGTGTC TTCAGGGGCCACACCAACCTTCTGAGGAGCTGTTGAGGTACCTCCAAGGACCGGCCTTTG CACCTCCATGGAAACGAAGCACCATCATTCCCGTTGAACGTCACATCTTTAACCCACTAA CTGGCTAATTAGCATGGCCACATCTGAGCCCCGAATCTGACATTAGATGAGAGAACAGGG CTGAAGCTGTGTCCTCATGAGGGCTGGATGCTCTCGTTGACCCTCACAGGAGCATCTCCT CAACTCTGAGTGTTAAGCGTTGAGCCACCAAGCTGGTGGCTCTGTGTGCTCTGATCCGAG CTCAGGGGGGTGGTTTTCCCATCTCAGGTGTGTTGCAGTGTCTGCTGGAGACATTGAGGC AGGCACTGCCAAAACATCAACCTGCCAGCTGGCCTTGTGAGGAGCTGGAAACACATGTTC CCCTTGGGGGTGGTGGATGAACAAAGAGAAAGAGGGTTTGGAAGCCAGATCTATGCCACA AGAACCCCCTTTACCCCCATGACCAACATCGCAGACACATGTGCTGGCCACCTGCTGAGC CCCAAGTGGAACGAGACAAGCAGCCCTTAGCCCTTCCCCTCTGCAGCTTCCAGGCTGGCG TGCAGCATCAGCATCCCTAGAAAGCCATGTGCAGCCACCAGTCCATTGGGCAGGCAGATG TTCCTAATAAAGCTTCTGTTCCGTGCTTGTCCCTGTGGAAGTATCTTGGTTGTGACAGAG TCAAGGGTGTGTGCAGCATTGTTGGCTGTTCCTGCAGTAGAATGGGGGCAGCACCTCCTA AGAAGGCACCTCTCTGGGTTGAAGGGCAGTGTTCCCTGGGGCTTTAACTCCTGCTAGAAC AGTCTCTTGAGGCACAGAAACTCCTGTTCATGCCCATACCCCTGGCCAAGGAAGATCCCT TTGTCCACAAGTAAAAGGAAATGCTCCTCCAGGGAGTCTCAGCTTCACCCTGAGGTGAGC ATCATCTTCTGGGTTAGGCCTTGCCTAGGCATAGCCCTGCCTCAAGCTATGTGAGCTCAC CAGTCCCTCCCCAAATGCTTTCCATGAGTTGCAGTTTTTTCCTAGTCTGTTTTCCCTCCT TGGAGACAGGGCCCTGTCGGTTTATTCACTGTATGTCCTTGGTGCCTGGAGCCTACTAAA TGCTCAATAAATAATGATCACAGGAAAAAAAAAAAAAAAAAA |
Protein Sequence | >3577 : length: 350 MSNITDPQMWDFDDLNFTGMPPADEDYSPCMLETETLNKYVVIIAYALVFLLSLLGNSLV MLVILYSRVGRSVTDVYLLNLALADLLFALTLPIWAASKVNGWIFGTFLCKVVSLLKEVN FYSGILLLACISVDRYLAIVHATRTLTQKRHLVKFVCLGCWGLSMNLSLPFFLFRQAYHP NNSSPVCYEVLGNDTAKWRMVLRILPHTFGFIVPLFVMLFCYGFTLRTLFKAHMGQKHRA MRVIFAVVLIFLLCWLPYNLVLLADTLMRTQVIQESCERRNNIGRALDATEILGFLHSCL NPIIYAFIGQNFRHGFLKILAMHGLVSKEFLARHRVTSYTSSSVNVSSNL |