| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 3572 |
Name | IL6ST |
Synonym | CD130|CDW130|GP130|IL-6RB;interleukin 6 signal transducer;IL6ST;interleukin 6 signal transducer |
Definition | CD130 antigen|IL-6 receptor subunit beta|IL-6R subunit beta|gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form|gp130, oncostatin M receptor|interleukin receptor beta chain|interleukin-6 receptor subunit beta|membrane glycoprotein 130 |
Position | 5q11.2 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Interleukin signaling pathway;PANTHER;P00036 |
Pathway | Jak-STAT signaling pathway;KEGG PATHWAY;hsa04630 |
Pathway | Cytokine-cytokine receptor interaction;KEGG PATHWAY;hsa04060 |
Pathway | IL6-mediated signaling events;PID Curated;200124 |
Pathway | IL27-mediated signaling events;PID Curated;200023 |
Disease | Embryoma;FunDO |
Disease | Heart failure;FunDO |
Disease | Dermatitis;FunDO |
Disease | Malignant glioma;FunDO |
Disease | Infectious lung disease;FunDO |
Disease | IMMUNE;GAD |
Disease | Multiple myeloma;FunDO |
Disease | Melanoma;FunDO |
Disease | Alopecia;FunDO |
Disease | Lung cancer;FunDO |
Disease | Obesity;FunDO |
Disease | Congenital abnormality;FunDO |
Disease | Liver disease;FunDO |
Disease | periodontitis;GAD |
Disease | Cervical cancer;FunDO |
Disease | Atherosclerosis;FunDO |
External Links | |
Links to Entrez Gene | 3572 |
Links to all GeneRIF Items | 3572 |
Links to iHOP | 3572 |
Sequence Information | |
Nucleotide Sequence | >3572 : length: 9117 ACTGGGGTGGCGCGCTACCTCTGCGGAGAAGGATCTGACAGTGTTCCGGAGCCGGGGCGA GCAGCCAAAAGGCCCGCGGAGTCGCGCTGGGCCGCCCCGGCGCAGCTGAACCGGGGGCCG CGCCTGCCAGGCCGACGGGTCTGGCCCAGCCTGGCGCCAAGGGGTTCGTGCGCTGTGGAG ACGCGGAGGGTCGAGGCGGCGCGGCCTGAGTGAAACCCAATGGAAAAAGCATGACATTTA GAAGTAGAAGACTTAGCTTCAAATCCCTACTCCTTCACTTACTAATTTTGTGATTTGGAA ATATCCGCGCAAGATGTTGACGTTGCAGACTTGGCTAGTGCAAGCCTTGTTTATTTTCCT CACCACTGAATCTACAGGTGAACTTCTAGATCCATGTGGTTATATCAGTCCTGAATCTCC AGTTGTACAACTTCATTCTAATTTCACTGCAGTTTGTGTGCTAAAGGAAAAATGTATGGA TTATTTTCATGTAAATGCTAATTACATTGTCTGGAAAACAAACCATTTTACTATTCCTAA GGAGCAATATACTATCATAAACAGAACAGCATCCAGTGTCACCTTTACAGATATAGCTTC ATTAAATATTCAGCTCACTTGCAACATTCTTACATTCGGACAGCTTGAACAGAATGTTTA TGGAATCACAATAATTTCAGGCTTGCCTCCAGAAAAACCTAAAAATTTGAGTTGCATTGT GAACGAGGGGAAGAAAATGAGGTGTGAGTGGGATGGTGGAAGGGAAACACACTTGGAGAC AAACTTCACTTTAAAATCTGAATGGGCAACACACAAGTTTGCTGATTGCAAAGCAAAACG TGACACCCCCACCTCATGCACTGTTGATTATTCTACTGTGTATTTTGTCAACATTGAAGT CTGGGTAGAAGCAGAGAATGCCCTTGGGAAGGTTACATCAGATCATATCAATTTTGATCC TGTATATAAAGTGAAGCCCAATCCGCCACATAATTTATCAGTGATCAACTCAGAGGAACT GTCTAGTATCTTAAAATTGACATGGACCAACCCAAGTATTAAGAGTGTTATAATACTAAA ATATAACATTCAATATAGGACCAAAGATGCCTCAACTTGGAGCCAGATTCCTCCTGAAGA CACAGCATCCACCCGATCTTCATTCACTGTCCAAGACCTTAAACCTTTTACAGAATATGT GTTTAGGATTCGCTGTATGAAGGAAGATGGTAAGGGATACTGGAGTGACTGGAGTGAAGA AGCAAGTGGGATCACCTATGAAGATACACTTGATAAGCCCCTGGGAAGCGGTTGATCCTG GAATTTTGGTTGGACCATCTAAAGCACCAAGTTTCTGGTATAAAATAGATCCATCCCATA CTCAAGGCTACAGAACTGTACAACTCGTGTGGAAGACATTGCCTCCTTTTGAAGCCAATG GAAAAATCTTGGATTATGAAGTGACTCTCACAAGATGGAAATCACATTTACAAAATTACA CAGTTAATGCCACAAAACTGACAGTAAATCTCACAAATGATCGCTATCTAGCAACCCTAA CAGTAAGAAATCTTGTTGGCAAATCAGATGCAGCTGTTTTAACTATCCCTGCCTGTGACT TTCAAGCTACTCACCCTGTAATGGATCTTAAAGCATTCCCCAAAGATAACATGCTTTGGG TGGAATGGACTACTCCAAGGGAATCTGTAAAGAAATATATACTTGAGTGGTGTGTGTTAT CAGATAAAGCACCCTGTATCACAGACTGGCAACAAGAAGATGGTACCGTGCATCGCACCT ATTTAAGAGGGAACTTAGCAGAGAGCAAATGCTATTTGATAACAGTTACTCCAGTATATG CTGATGGACCAGGAAGCCCTGAATCCATAAAGGCATACCTTAAACAAGCTCCACCTTCCA AAGGACCTACTGTTCGGACAAAAAAAGTAGGGAAAAACGAAGCTGTCTTAGAGTGGGACC AACTTCCTGTTGATGTTCAGAATGGATTTATCAGAAATTATACTATATTTTATAGAACCA TCATTGGAAATGAAACTGCTGTGAATGTGGATTCTTCCCACACAGAATATACATTGTCCT CTTTGACTAGTGACACATTGTACATGGTACGAATGGCAGCATACACAGATGAAGGTGGGA AGGATGGTCCAGAATTCACTTTTACTACCCCAAAGTTTGCTCAAGGAGAAATTGAAGCCA TAGTCGTGCCTGTTTGCTTAGCATTCCTATTGACAACTCTTCTGGGAGTGCTGTTCTGCT TTAATAAGCGAGACCTAATTAAAAAACACATCTGGCCTAATGTTCCAGATCCTTCAAAGA GTCATATTGCCCAGTGGTCACCTCACACTCCTCCAAGGCACAATTTTAATTCAAAAGATC AAATGTATTCAGATGGCAATTTCACTGATGTAAGTGTTGTGGAAATAGAAGCAAATGACA AAAAGCCTTTTCCAGAAGATCTGAAATCATTGGACCTGTTCAAAAAGGAAAAAATTAATA CTGAAGGACACAGCAGTGGTATTGGGGGGTCTTCATGCATGTCATCTTCTAGGCCAAGCA TTTCTAGCAGTGATGAAAATGAATCTTCACAAAACACTTCGAGCACTGTCCAGTATTCTA CCGTGGTACACAGTGGCTACAGACACCAAGTTCCGTCAGTCCAAGTCTTCTCAAGATCCG AGTCTACCCAGCCCTTGTTAGATTCAGAGGAGCGGCCAGAAGATCTACAATTAGTAGATC ATGTAGATGGCGGTGATGGTATTTTGCCCAGGCAACAGTACTTCAAACAGAACTGCAGTC AGCATGAATCCAGTCCAGATATTTCACATTTTGAAAGGTCAAAGCAAGTTTCATCAGTCA ATGAGGAAGATTTTGTTAGACTTAAACAGCAGATTTCAGATCATATTTCACAATCCTGTG GATCTGGGCAAATGAAAATGTTTCAGGAAGTTTCTGCAGCAGATGCTTTTGGTCCAGGTA CTGAGGGACAAGTAGAAAGATTTGAAACAGTTGGCATGGAGGCTGCGACTGATGAAGGCA TGCCTAAAAGTTACTTACCACAGACTGTACGGCAAGGCGGCTACATGCCTCAGTGAAGGA CTAGTAGTTCCTGCTACAACTTCAGCAGTACCTATAAAGTAAAGCTAAAATGATTTTATC TGTGAATTCAGATTTTAAAAAGTCTTCACTCTCTGAAGATGATCATTTGCCCTTAAGGAC AAAAATGAACTGAAGTTTCACATGAGCTATTTCCATTCCAGAATATCTGGGATTCTACTT TAAGCACTACATAAACTGACTTTATCCTCAGACTAGCTGAATGATTTTGTGCTGTTTCAG GATGTTTGCACTGAAGAAAAACAGAAAGCTTATCTGAAATTTATAAAACTTTTTGTTTTG CTACATAGAAAACAGAAGGTATTTGAATAATAAGCAGTGATATGCTTAGTGAGCACAGCT ATACTGATTTTGATTAGAATAGTCATCAGAGTGGCTTAGGGACAGTTAATATAAAAGAGG AGCAAGGTGTAGACCATCATCTACTTCTGCTAAAATAACTTAAAAAGAGGTCCATAGGCC ATAACTACATGAGCCCAGCTTTTGTAATCTGACAAAAAAATGAGGAGCAGCTTCGTGTAT ATCAGTGTACACGGTATTCCTTAGGTCCCTTCCATTGGTAGTGATGCTGCGAGTTATTAC TGGAGAAAAGGAATTCTAGAGCTTTAACTTGGCAGATTAAAAGTACTCATTTTTTATTCA TCAATAATTAGTAATCTCACTAGTTTTCAAAAATTTGCATATTATTGACAACCTCTTTGA AGATGCATTTCACAAACTCAACAGAGTGCCATGATAAGAGCTAGGGATCCCCCAAACTAT CTCAAGCATCTAAAAAATTGCCATTTTTAAAGGCTTAAATTGTAGTAGTAAAGGGGAAAA CAGGAAGTAGTAGTAAAGGGGAAAAAAAACCAATAAAGCATCTAAAAAATTGGCATGTTA AAAGGCTTAAATTGCTAATGTGTGTATATATATATATATATATACACACACATATCATTG ACTTTTCTTAAGACTTCAGAGTACTGGGTAGATGAACACTTTATACAGTATATATCTTCA GCTTAAATTTGTTTTGAGTATTTTTTTTATTTTTAAATAAGTAGGCAAAGATTTAAATTT TTTTATTTTTAGTAAATGTTTGAGGCACACTAAGACAACTTGGGCAATATTTGCCAAAAC AAAACAGAACCCCAAAAAATGTACATCTTGTTCTTAGCAAATATCATTATTGTAGAGACA CTTAATAAAGAGATGGTATTTTAATGTCTGCAGTTCTGAGGTAGGGTGGAACTTAGTTCT ACATTGTGATTTAGGAATTTTTAAAACCTTTTTTCTTCAAGGGAGAAGTGACCCAGGCCT CGAGTTTAGTGCTAAAGCCGCTAGTGTACTTATGCTGTCCCCTAACCACCACGTGCGATA TGGAAGCAGATGCTAAATATAGGGGTTTTCTTAGAAAGTAAGAGGAAATTAGCAAGCGTT ATTAGTGATTGACTACTGCTATCAAGTGAATTCAAAGGAAACAGGTTTTTATGCCATATT TAAGTTACAGAAACCAGGCATGCTTAGAATAGTTTCTAGAGGTTATTGGAGAATAGAAAG CTAAGAAAACTTGGTATACATTTACAATGGAAATATAATTACACTTTTTACTCTCAGAAT ATTGTTCACATTAGACTTCCTGTTTATCTTTTATATTCTTGCATTTATATAATGCCTCAT CCTTTCAAAGTTCTTTCACATATTATATGATCTTCTTTATGAAAAAAATAGATGTTTCAT TCTGATATATTCAGTTTCCCACTTTAGGCAAAAGTAGATTAATAGAATGACGAATTCAAA GTAGATGAGGAAAATCAGGCACAGAGAAGTAAAGGTAGGGATAGACCCAAATTTACACAA CAAGATAATGACATCTCCAGCTTTTAAGTTGATCATCAAAGGCTGGGCTGGATTTGTCTT GCTGTATGTGTCAGGAAATTTATACCTATTACATTTTCCATTTTCTCAAAATTTAAGTCA CATGACTAATATTTAGCTGCAACTTTCCTCATAACAAATAGTGTCATGAAGAATGTTGTA GTGTGAAGTTTGTACATTTCAGGGTCAGATATACAATATGAACTCTTAATCTACAGGAAT GAGAATGGAGGATCATTGAAGGCCATGATATAAACAAATTTGCATGTTGAAGCCTGTATA AAACATGGTACAGTGAGTGAATATACCCCCATCCCCAAGAACACTTTATACATATTAAAT GGATATATGATTACTGTGCAAAAATTCATTCTGGAAATGAACATATATTTGAGCACTAAT ATGTAATGTACACCTGCCCTAAGGAGAAAATAAATTATAAAACTTTTTACATTCAAAATT ACTTTCCCAAGCATGTCTTAGAATAATCTATGTGTTGATGCATGTAAATTGTACTTTAGG TAGGCAAAGAAATCTGGTTATTTATGTAAAAACTAGTCTAATAAAGTTAGTTAGTGGCTT TATCACTTTAAATCTTTAGTGTCCAAAAGTGGTGTTTAAAGTAATAGCACATCAGAAAAC CTTGTCTGGACAAAACTAGTTCACTCACTGCTTCTGCACCTGCAGTTGCTCCCTTTAGGG TTATAAAATAATGACCCAAATGTTACATGTGTTGATATTATAACTTGTCAGTTACTGATG TCTGTGGTATCCTACCCTCATCTCTGAAAGGGATAATACTGAATAATTATTAGAAAACTA TAAAACTTCACACTTTGTACCATTAAAACCTAAAATTTTAATCTTGTCCTTTTTTACTAT GGATCAGTCGGCACTCGGGAACAGCAGCAAGGAAAAAAAGCAAATTTCATTCACATGTTC TGTGTTCATACCTCTTCTCTACCTAATTGTTCATTTAAATTTCAGCCTTATTCCTTGATA AGGGATTTTACCACATGAAGTCATCCAGTGACCCTAGCTCTTATTGTGAAGTTAGTGGAG TATACTTAGAAATGTTACAACTTTAAAATGTTACAAAACATTCATTAAAGCTCATATTTA AAGTAGAGCATCTAGTTTGAGAAATAGAAATCAATTATTAAAGATGTCTTTTTTCTACCC ATTTAACTAGTTAAAACCATGACATGTAAATGTAGAAGTAGAATAATCATAGAATTCCCT AAAATATTTCTGTTTACTAACATATATTGACCAAGTACATCAAGCAGGAGAGATCTTCCT TCATTCTGTTATAGTCCACATCATTCTAATTTTGCTCAGTTGTTATTAAGAGCATATTCC TAAACCATACACTTTTGTTTCAATAAAGTTTTATTTTGTTGAGATGAATAAAATAACAAA GTTATAAGCTGCATAAGACAAAAGTTCAATTGTTCAAAAAAAATTTACTGGGATAGCTTT CTATTACAGGTATTGTTAGATTATATTGTGCTGATAAGATTACTTTCTAAAAAATTTGTA CTTTTCTGTAAATTAAAAGAATATGGAGTCATAAAATGGCAAGTGTTTTAGGATTAGCCT AAAATTGGACATTGTCATTGATTTCAAAGAAGGTATGAACTAGCAGTCTTACAGCCTAAT TCTTCTTTGGACTGGTCCTTGGCAGCAGTTCCTTTTCAGACTCGATAAACAGAATTCAGA TGATGTAAGTCAAAACAAAACTTTACAAAGCCAAGCGTATTATCTTTTGCATTAACCTAT TTTTTTCCATCATACATGCTACTAGTATGTGCATTAGCATGATATTCTCATATACATTGC ATTAAAAATTAAAAGGTGGCAGCTCAGGGTGAGCTCTTCTGTTGCTCATTTGTTCCTAAA TTTTTAAGGGCTTTTTCTCAGTCAATAGTTTGTACAAACTGGTTAGTTTAACTTCATTAC CCATTTCATTAAAGTTGATGGGTCGTGTGATGAGATGCATTTAAGGCCGATAGTGATAGA TGTTTTTTTTATTTCTTGAACACAGGCTTTGTCTGAATGATGTTCTTTTATCTCTTGAAC ACAAGCTTTGAATGATAACTACAGGTTTTAAGTGCTGTTACATTAATACCATAATGTGAT GTGTTAGAAACAAAGGGATATTTCAAAGGTAGATATTTGAAAATTCTCTAGTCTCAATAT GTATGTGTATTGAATATACTCTAAAAATAAATGTGCAATTTGCTAGTAGGACAATGCAGT GACTGACTAGCATTAGGTATGTTTCTTTTATATCCTAGCTATGTCCCACTTTCTTCTAAG TGCAATCCTTTCATGTTCACTTGCTGTTTTACCCCATCTACTCTAACTTCATTTGGAAGG CTTGTCTAGAGTATAGCATGTATTTTTACCTTTGCAGTGAATTGCATGTGCTAATTGTAA CCACAGCTATTTTTATGTTGACATAACTCCAAATGTTATATTAAATGTTCTATTATATAT TAGCTCTAATCCCTTAAGTAAATTTTAAGAAATAAATACTTGTTCAAATTTTTTTTCTGT ATGTGGTTACTATCATCTGACTATGCATATTTGTAACAGCATTTATCATTAGTGGTGTTA GCTAAATAAGCATCTTAGTGTAAATGAGATGCTTCGTGTGGGTTTTGTGACATTTTAAAT GACATAATGGAATGTGATTTAAAAGAAAACCAGTACACTATCTTGGTCTTAATAACATAG AATGGAGATGGCAAATTTATCCACTAGTTTTCCAGATTTACTATTTAATAGCTGAGGTCT GAAATCGTAGCATCCTCCCTCCTAGTGGACATTAAAAAAAAAAAAAAAAAAAAAAACCTA CTTGGTTGTCAAGAGCCCAAGTATGGAGGTGCTGCGCCATCTTGTGGCCTGTCTGTGCCC ACCCTGCACTCTGCTGGAGTCTCCATCCTTGTTGCAGTGAGACTTGAAGTTCAAGATTGA TACATGGCATCCTCCTGCTACTTCTTGAGGTTACTAAGTAGTATATGAAACTAATCAGTC AGCAAGTCCACCTGGAAGGAAAAGAAAATCTCAACTATTAATGTGCCTTCACATTGTGAT TTTGTCTAAAAAAATGTAGTGAGTCAAAAAACCCACAAGCCAGCCAACAGTAACTCCTTC ACATATATACCAGAGTTTATAGAAATAACATGTCAGCTTTGGGCTATGTGCTCCTTTGTT TAAAATCTTCTATTTGGTTATGGCTTGTATAGGCTCAAGCCTGATTTCTTTAAGGTGTGG TGGCTCATCTTATCCTAATGTGTATGATAGATACAGTCCATCCTGCTTTGGAAAAGATTA TGTAACTCCTTGAGAGCATACTCTTTCTCTAGCCCAAAGGCAGTGAGAGAGTTTTCTTGT TCAGGATTGCTTAACTTTCCATTTAAGCTTTTTCTTTTTAAATTAATACAAACTTCTACA CTTTCAAAATACGAAATATATTACAACTGCGTATAGGCTCTTCCATACTTAAGTCCAGTG CTTGGGCAAGTTAATGGAGTGAAAGACTACAAGCAAAGAGGAACTGAGGTAGAAAAAGAA GAATGTGTGAAAGCAGCAGGAAGCTCAGCCAACTCGAAAGCAGGGTGAACAGCTTGAGTC CTGTTGCTGCTGATCGGGGTTGGCTCTTGGACAACTTAGTAAGATCATGGAAAGGCTGCT TGGGTTCTCCATAGAAAAGTTCTGTCTCCATCAAGGGAGGAAAATGTACCTTTCAACTCA AAATTCAATATTTGTTTTTAAATATAGCTATTTTCCCCAACCGCTAAAGATTTTCAACAG ATACGAAGCCAGAGCTTAGTTTTAGAAACCTGTGGACATTCAAACCTGATTCTTTATTCC CTGTGACTATGGTTATGTCATTTTACATGTCAAAAAAGTGTATCTAGAATTGTCATTTCT TATTTTTGAGCTTTTTTTAGTGAGAATTATCCCCTCACTTAAATGGCTTTTTATTTAAAC ATCTGTGCATTCTGTATGAAATTGTAGTCTTTCTGGGATAACATGGTGAGCTATATGGTG GTAATCCACACACACAAAAATAAAAGCCAAAAAAAAACCAAAAAAAAAAAAAAAAAA |
Protein Sequence | >3572 : length: 918 MLTLQTWLVQALFIFLTTESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHV NANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITI ISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPT SCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSIL KLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIR CMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEAN GKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACD FQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRT YLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWD QLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGG KDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSK SHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKIN TEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYRHQVPSVQVFSRS ESTQPLLDSEERPEDLQLVDHVDGGDGILPRQQYFKQNCSQHESSPDISHFERSKQVSSV NEEDFVRLKQQISDHISQSCGSGQMKMFQEVSAADAFGPGTEGQVERFETVGMEAATDEG MPKSYLPQTVRQGGYMPQ |