| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 29102 |
Name | DROSHA |
Synonym | ETOHI2|HSA242976|RANSE3L|RN3|RNASE3L|RNASEN;drosha, ribonuclease type III;DROSHA;drosha, ribonuclease type III |
Definition | RNase III|drosha, double-stranded RNA-specific endoribonuclease|nuclear RNase III Drosha|p241|protein Drosha|putative protein p241 which interacts with transcription factor Sp1|putative ribonuclease III|ribonuclease 3|ribonuclease III, nuclear|ribonucleas |
Position | 5p13.3 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Regulatory RNA pathways;Reactome;REACT:12472 |
Pathway | Direct p53 effectors;PID Curated;200101 |
Disease | Leukemia;FunDO |
Disease | Cervical cancer;FunDO |
Disease | Esophagus cancer;FunDO |
External Links | |
Links to Entrez Gene | 29102 |
Links to all GeneRIF Items | 29102 |
Links to iHOP | 29102 |
Sequence Information | |
Nucleotide Sequence | >29102 : length: 5424 ACCGCGCACAAGGCCCTGCGGTGGGCTGAAGAGTTTTCCCTCCCTTGGCCCAGCTTTCTC AGGTTTGCTTTTTAATTCCCTCGGTTTCCTGTTCCGGAGGCGCGGGCGGTGCCACTGTCT TGGTACCTGCGGTAGTAGCCTGGCTTTGCTCTGACGGCGATCTCGCGGCCCGAGAGCCTT TTATAGGTTGCTTTTCCCGGGGATGTGAAGGATACAGAAATGACTGTGAATCAACCCATA TCATCAAGGAGCTGATAATCTAGTGGAAGAGTTAGACGTGTGCATACTTCACTATGATAT GAGGCAGTCTCTGAGCTTATATTCTCTGTGGAAGATGTGACATATCCAGGCGGAACATCA TGATGCAGGGAAACACATGTCACAGAATGTCGTTCCACCCGGGACGAGGGTGTCCCCGAG GACGAGGAGGACATGGAGCCAGACCCTCAGCACCATCCTTTAGGCCCCAAAATCTGAGGC TGCTTCACCCTCAGCAGCCTCCTGTGCAATATCAATATGAACCTCCAAGTGCCCCTTCCA CCACTTTCTCAAACTCTCCAGCCCCCAATTTTCTCCCTCCACGACCAGACTTTGTACCCT TCCCCCCACCCATGCCTCCGTCAGCGCAAGGCCCTCTTCCCCCCTGCCCAATCAGGCCGC CTTTCCCCAACCACCAGATGAGGCACCCCTTCCCAGTTCCTCCTTGTTTTCCTCCCATGC CACCACCAATGCCTTGTCCTAATAACCCCCCAGTCCCTGGGGCACCTCCTGGACAAGGCA CTTTCCCCTTCATGATGCCCCCTCCCTCCATGCCTCATCCCCCGCCCCCTCCAGTCATGC CGCAGCAGGTTAATTATCAGTACCCTCCGGGCTATTCTCACCACAACTTCCCACCTCCCA GTTTTAATAGTTTCCAGAACAACCCTAGTTCTTTCCTGCCCAGTGCTAATAACAGCAGTA GTCCTCATTTCAGACATCTCCCTCCATACCCACTCCCAAAGGCTCCCAGTGAGAGAAGGT CCCCAGAAAGGCTGAAACACTATGATGACCACAGGCACCGAGATCACAGTCATGGGCGAG GTGAGAGGCATCGGTCCCTGGATCGGCGGGAGCGAGGCCGCAGTCCCGACAGGAGAAGAC AAGACAGCCGGTACAGATCTGATTATGACCGAGGGAGAACACCATCTCGCCACCGCAGCT ACGAACGGAGCAGAGAGCGAGAACGGGAGAGACACAGGCATCGAGACAACCGAAGATCAC CATCTCTGGAAAGGTCCTACAAAAAAGAGTATAAGAGATCTGGAAGGAGTTACGGTTTAT CGGTTGTTCCTGAACCTGCTGGATGCACACCAGAATTACCTGGGGAGATTATTAAAAATA CAGATTCTTGGGCCCCACCCCTGGAGATTGTGAATCATCGCTCCCCAAGTAGGGAGAAGA AGAGAGCTCGTTGGGAGGAAGAAAAAGACCGTTGGAGTGACAACCAGAGTTCTGGCAAAG ACAAGAACTATACCTCAATCAAGGAAAAAGAGCCCGAGGAGACCATGCCTGACAAGAATG AGGAGGAAGAAGAAGAACTTCTTAAGCCTGTGTGGATTCGATGCACTCATTCAGAAAACT ACTACTCCAGTGACCCCATGGATCAGGTGGGAGATTCTACAGTGGTTGGAACGAGTAGGC TTCGTGACTTATATGACAAATTTGAGGAGGAGTTGGGGAGCAGGCAAGAAAAGGCCAAAG CTGCTCGGCCTCCGTGGGAACCTCCAAAGACGAAGCTCGATGAAGATTTAGAGAGTTCCA GTGAATCCGAGTGTGAGTCTGATGAGGACAGCACCTGTTCTAGCAGCTCAGACTCTGAAG TTTTTGACGTTATTGCAGAAATCAAACGCAAAAAGGCCCACCCTGACCGACTTCATGATG AACTTTGGTACAACGATCCAGGCCAGATGAATGATGGACCACTCTGCAAATGCAGCGCAA AGGCAAGACGCACAGGAATTAGGCACAGCATTTATCCTGGAGAAGAGGCCATCAAGCCCT GTCGTCCTATGACCAACAATGCTGGCAGACTTTTCCACTACCGGATCACAGTCTCCCCGC CTACGAACTTTTTAACTGACAGGCCAACTGTTATAGAATACGATGATCACGAGTATATCT TTGAAGGATTTTCTATGTTTGCACATGCCCCCCTGACCAATATTCCACTGTGTAAAGTAA TTAGATTCAACATAGACTACACGATTCATTTCATTGAAGAGATGATGCCGGAGAATTTTT GTGTGAAAGGGCTTGAACTCTTTTCACTGTTCCTATTCAGAGATATTTTGGAATTATATG ACTGGAATCTTAAAGGTCCTTTGTTTGAAGACAGCCCTCCCTGCTGCCCAAGATTTCATT TCATGCCACGTTTTGTAAGATTTCTTCCAGATGGAGGAAAGGAAGTGCTGTCCATGCACC AGATTCTCCTGTACTTGTTAAGGTGCAGCAAAGCCCTGGTGCCTGAGGAGGAGATTGCCA ATATGCTTCAGTGGGAGGAGCTGGAGTGGCAGAAATATGCAGAAGAATGCAAAGGCATGA TTGTTACCAACCCTGGGACGAAACCAAGCTCTGTCCGTATCGATCAACTGGATCGTGAAC AGTTCAACCCCGATGTGATTACTTTTCCGATTATCGTCCACTTTGGGATACGCCCTGCAC AGTTGAGTTATGCAGGAGACCCACAGTACCAAAAACTGTGGAAGAGTTATGTGAAACTTC GCCACCTCCTAGCAAATAGTCCCAAAGTCAAACAAACTGACAAACAGAAGCTGGCACAGA GGGAGGAAGCCCTCCAAAAAATACGGCAGAAGAATACAATGAGACGAGAAGTAACGGTGG AGCTAAGTAGCCAAGGATTCTGGAAAACTGGCATCCGTTCTGATGTCTGTCAGCATGCAA TGATGCTACCTGTTCTGACCCATCATATCCGCTACCACCAATGCCTAATGCATTTGGACA AGTTGATAGGATATACTTTCCAAGATCGTTGTCTGTTGCAGCTGGCCATGACTCATCCAA GTCATCATTTAAATTTTGGAATGAATCCTGATCATGCCAGGAATTCATTATCTAACTGTG GAATTCGGCAGCCCAAATACGGAGACAGAAAAGTTCATCACATGCACATGCGGAAGAAAG GGATTAACACCTTGATAAATATCATGTCACGCCTTGGCCAAGATGACCCAACTCCCTCGA GGATTAACCACAATGAACGGTTGGAATTCCTGGGTGATGCTGTTGTTGAATTTCTGACCA GCGTCCATTTGTACTATTTGTTTCCTAGTCTGGAAGAAGGAGGATTAGCAACCTATCGGA CTGCCATTGTTCAGAATCAGCACCTTGCCATGCTAGCAAAGAAACTTGAACTGGATCGAT TTATGCTGTATGCTCACGGGCCTGACCTTTGTAGAGAATCGGACCTTCGACATGCAATGG CCAATTGTTTTGAAGCGTTAATAGGAGCTGTTTACTTGGAGGGAAGCCTGGAGGAAGCCA AGCAGTTATTTGGACGCTTGCTCTTTAATGATCCGGACCTGCGCGAAGTCTGGCTCAATT ATCCTCTCCACCCACTCCAACTACAAGAGCCAAATACTGATCGACAACTTATTGAAACTT CTCCAGTTCTACAAAAACTTACTGAGTTTGAAGAAGCAATTGGAGTAATTTTTACTCATG TTCGACTTCTGGCAAGGGCATTCACATTGAGAACTGTGGGATTTAACCATCTGACCCTAG GCCACAATCAGAGAATGGAATTCCTAGGTGACTCCATAATGCAACTGGTAGCCACAGAGT ACTTATTCATTCATTTCCCAGATCATCATGAAGGACACTTAACTTTGTTGCGAAGCTCTT TGGTGAATAATAGAACTCAGGCCAAGGTAGCGGAGGAGCTGGGCATGCAGGAGTACGCCA TAACCAACGACAAGACCAAGAGGCCTGTGGCGCTTCGCACCAAGACCTTGGCGGACCTTT TGGAATCATTTATTGCAGCGCTGTACATTGATAAGGATTTGGAATATGTTCATACTTTCA TGAATGTCTGCTTCTTTCCACGATTGAAAGAGTTCATTTTGAATCAGGATTGGAATGACC CCAAATCCCAGCTTCAGCAGTGTTGCTTGACACTTAGGACAGAAGGAAAAGAGCCAGACA TTCCTCTGTACAAGACTCTGCAGACAGTGGGCCCATCCCATGCCCGAACCTACACTGTGG CTGTTTATTTCAAGGGAGAAAGAATAGGCTGTGGGAAAGGACCAAGTATTCAGCAAGCGG AAATGGGAGCAGCAATGGATGCGCTTGAAAAATATAATTTTCCCCAGATGGCCCATCAGA AGCGGTTCATCGAACGGAAGTACAGACAAGAGTTAAAAGAAATGAGGTGGGAAAGAGAGC ATCAAGAGAGAGAGCCAGATGAGACTGAAGACATCAAGAAATAAAGGAGGGCATGCAAGT GTGGAGTATTTACTTGCTCAGTAACTGTGACTGTTGTCTATTGAGACCTAGCCTAGTTTT CCTGCAGACAATGAATGAAGTGTGCTCATTGAAATAAAATACAGAGTCAAATCGCTATTG TTGTTTTAATGATCTGTTTTTAGCTGGATGGTCTTTATTACAAAGTATTAGATTTTTCTT CTATTTAACGGAAAACTTGACTTTGGTGAATGTGCATTACTTCCTTTTATTTTGCTCTTT AAATAATAAAATTCAAGAAGCATATTCTATGTGGAATAGATCCTGTTTTTCCATCTGTGT CCCAGATTGTGACCCTAGACTTTCAATTGACAAGTAAAAAATTGACTTTACTAGACATTT TGACTGTGCTCTAGTAACATCTATCCTTTTTCAAATCTCTGGATTTTTAAGTAGATTGTT CAGCTTTCATCCGGTGGCTGTTCATCAAGTTATCAGCTGCAAATATTGAACTTACCTCTC TCTAAGCAGTGAGTGTTTTGTAGAAGGAATCCGTTTAACAATTAATTGGCTAATGGGAGA AGGGGAAAGACTGATATTCAAGTCATACAGATTCTTTGAATCATTAGAATAGGAGAGAAA TCATGATTCTAAGCCAGGCCACACTTTAAACCAAGTGCTCTCACCCTGGGGTTAGTGGAA CCTTTAAGAAGTTAATGAACAGACTTCAAGGAAGTCAAAAACCTCCCAATACTATATTCA ATTTTCTGTGTGTGTTTGAGATTTGAGAGGGCATGGGGAGCAGGAAGGAGGAGGGTTTAT AGCTTTTATCAGCCTCTCTAAGTGGGCCCTGCAGTAAAAGGCTAACATGACATTCAAAGA CATAACATTTTAAAAAAAGTTATTCCAAACTAAACATCACTGGTTTCTTATTAATAAAGG CAAAACTTCTTTGTAAAACAAAAA |
Protein Sequence | >29102 : length: 1374 MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPS TTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPM PPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPP SFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGR GERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRS PSLERSYKKEYKRSGRSYGLSVVPEPAGCTPELPGEIIKNTDSWAPPLEIVNHRSPSREK KRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSEN YYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESS SESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSA KARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYI FEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELY DWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIA NMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPA QLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTV ELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHP SHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPS RINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDR FMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLN YPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTL GHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYA ITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWND PKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQA EMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPDETEDIKK |