| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 246 |
Name | ALOX15 |
Synonym | 12-LOX|15-LOX-1|15LOX-1;arachidonate 15-lipoxygenase;ALOX15;arachidonate 15-lipoxygenase |
Definition | 12/15-lipoxygenase|15-LOX|15-lipooxygenase-1|arachidonate 12-lipoxygenase, leukocyte-type|arachidonate omega-6 lipoxygenase |
Position | 17p13.3 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Inflammation mediated by chemokine and cytokine signaling pathway;PANTHER;P00031 |
Pathway | Linoleic acid metabolism;KEGG PATHWAY;hsa00591 |
Pathway | IL4-mediated signaling events;PID Curated;200018 |
Pathway | Metabolic pathways;KEGG PATHWAY;hsa01100 |
Pathway | Arachidonic acid metabolism;KEGG PATHWAY;hsa00590 |
Disease | bone density;GAD |
Disease | atherosclerosis, coronary;GAD |
Disease | Osteoporosis;FunDO |
Disease | CARDIOVASCULAR;GAD |
Disease | Cancer;FunDO |
Disease | METABOLIC;GAD |
Disease | Alzheimer's disease;FunDO |
Disease | Atherosclerosis;FunDO |
External Links | |
Links to Entrez Gene | 246 |
Links to all GeneRIF Items | 246 |
Links to iHOP | 246 |
Sequence Information | |
Nucleotide Sequence | >246 : length: 2707 CATCTTTGAGCAAGATGGGTCTCTACCGCATCCGCGTGTCCACTGGGGCCTCGCTCTATG CCGGTTCCAACAACCAGGTGCAGCTGTGGCTGGTCGGCCAGCACGGGGAGGCGGCGCTCG GGAAGCGACTGTGGCCCGCACGGGGCAAGGAGACAGAACTCAAGGTGGAAGTACCGGAGT ATCTGGGGCCGCTGCTGTTTGTGAAACTGCGCAAACGGCACCTCCTTAAGGACGACGCCT GGTTCTGCAACTGGATCTCTGTGCAGGGCCCCGGAGCCGGGGACGAGGTCAGGTTCCCTT GTTACCGCTGGGTGGAGGGCAACGGCGTCCTGAGCCTGCCTGAAGGCACCGGCCGCACTG TGGGCGAGGACCCTCAGGGCCTGTTCCAGAAACACCGGGAAGAAGAGCTGGAAGAGAGAA GGAAGTTGTACCGGTGGGGAAACTGGAAGGACGGGTTAATTCTGAATATGGCTGGGGCCA AACTATATGACCTCCCTGTGGATGAGCGATTTCTGGAAGACAAGAGAGTTGACTTTGAGG TTTCGCTGGCCAAGGGGCTGGCCGACCTCGCTATCAAAGACTCTCTAAATGTTCTGACTT GCTGGAAGGATCTAGATGACTTCAACCGGATTTTCTGGTGTGGTCAGAGCAAGCTGGCTG AGCGCGTGCGGGACTCCTGGAAGGAAGATGCCTTATTTGGGTACCAGTTTCTTAATGGCG CCAACCCCGTGGTGCTGAGGCGCTCTGCTCACCTTCCTGCTCGCCTAGTGTTCCCTCCAG GCATGGAGGAACTGCAGGCCCAGCTGGAGAAGGAGCTGGAGGGAGGCACACTGTTCGAAG CTGACTTCTCCCTGCTGGATGGGATCAAGGCCAACGTCATTCTCTGTAGCCAGCAGCACC TGGCTGCCCCTCTAGTCATGCTGAAATTGCAGCCTGATGGGAAACTCTTGCCCATGGTCA TCCAGCTCCAGCTGCCCCGCACAGGATCCCCACCACCTCCCCTTTTCTTGCCTACGGATC CCCCAATGGCCTGGCTTCTGGCCAAATGCTGGGTGCGCAGCTCTGACTTCCAGCTCCATG AGCTGCAGTCTCATCTTCTGAGGGGACACTTGATGGCTGAGGTCATTGTTGTGGCCACCA TGAGGTGCCTGCCGTCGATACATCCTATCTTCAAGCTTATAATTCCCCACCTGCGATACA CCCTGGAAATTAACGTCCGGGCCAGGACTGGGCTGGTCTCTGACATGGGAATTTTCGACC AGATAATGAGCACTGGTGGGGGAGGCCACGTGCAGCTGCTCAAGCAAGCTGGAGCCTTCC TAACCTACAGCTCCTTCTGTCCCCCTGATGACTTGGCCGACCGGGGGCTCCTGGGAGTGA AGTCTTCCTTCTATGCCCAAGATGCGCTGCGGCTCTGGGAAATCATCTATCGGTATGTGG AAGGAATCGTGAGTCTCCACTATAAGACAGACGTGGCTGTGAAAGACGACCCAGAGCTGC AGACCTGGTGTCGAGAGATCACTGAAATCGGGCTGCAAGGGGCCCAGGACCGAGGGTTTC CTGTCTCTTTACAGGCTCGGGACCAGGTTTGCCACTTTGTCACCATGTGTATCTTCACCT GCACCGGCCAACACGCCTCTGTGCACCTGGGCCAGCTGGACTGGTACTCTTGGGTGCCTA ATGCACCCTGCACGATGCGGCTGCCCCCGCCAACCACCAAGGATGCAACGCTGGAGACAG TGATGGCGACACTGCCCAACTTCCACCAGGCTTCTCTCCAGATGTCCATCACTTGGCAGC TGGGCAGACGCCAGCCCGTTATGGTGGCTGTGGGCCAGCATGAGGAGGAGTATTTTTCGG GCCCTGAGCCTAAGGCTGTGCTGAAGAAGTTCAGGGAGGAGCTGGCTGCCCTGGATAAGG AAATTGAGATCCGGAATGCAAAGCTGGACATGCCCTACGAGTACCTGCGGCCCAGCGTGG TGGAAAACAGTGTGGCCATCTAAGCGTCGCCACCCTTTGGTTATTTCAGCCCCCATCACC CAAGCCACAAGCTGACCCCTTCGTGGTTATAGCCCTGCCCTCCCAAGTCCCACCCTCTTC CCATGTCCCACCCTCCCTAGAGGGGCACCTTTTCATGGTCTCTGCACCCAGTGAACACAT TTTACTCTAGAGGCATCACCTGGGACCTTACTCCTCTTTCCTTCCTTCCTCCTTTCCTAT CTTCCTTCCTCTCTCTCTTCCTCTTTCTTCATTCAGATCTATATGGCAAATAGCCACAAT TATATAAATCATTTCAAGACTAGAATAGGGGGATATAATACATATTACTCCACACCTTTT ATGAATCAAATATGATTTTTTTGTTGTTGTTAAGACAGAGTCTCACTTTGACACCCAGGC TGGAGTGCAGTGGTGCCATCACCACGGCTCACTGCAGCCTCAGCGTCCTGGGCTCAAATG ATCCTCCCACCTCAGCCTCCTGAGTAGCTGGGACTACAGGCTCATGCCATCATGCCCAGC TAATATTTTTTTATTTTCGTGGAGACGGGGCCTCACTATGTTGCCTAGGCTGGAAATAGG ATTTTGAACCCAAATTGAGTTTAACAATAATAAAAAGTTGTTTTACGCTAAAGATGGAAA AGAACTAGGACTGAACTATTTTAAATAAAATATTGGCAAAAGAAAAAAAAAAAAAAAAAA AAAAAAA |
Protein Sequence | >246 : length: 662 MGLYRIRVSTGASLYAGSNNQVQLWLVGQHGEAALGKRLWPARGKETELKVEVPEYLGPL LFVKLRKRHLLKDDAWFCNWISVQGPGAGDEVRFPCYRWVEGNGVLSLPEGTGRTVGEDP QGLFQKHREEELEERRKLYRWGNWKDGLILNMAGAKLYDLPVDERFLEDKRVDFEVSLAK GLADLAIKDSLNVLTCWKDLDDFNRIFWCGQSKLAERVRDSWKEDALFGYQFLNGANPVV LRRSAHLPARLVFPPGMEELQAQLEKELEGGTLFEADFSLLDGIKANVILCSQQHLAAPL VMLKLQPDGKLLPMVIQLQLPRTGSPPPPLFLPTDPPMAWLLAKCWVRSSDFQLHELQSH LLRGHLMAEVIVVATMRCLPSIHPIFKLIIPHLRYTLEINVRARTGLVSDMGIFDQIMST GGGGHVQLLKQAGAFLTYSSFCPPDDLADRGLLGVKSSFYAQDALRLWEIIYRYVEGIVS LHYKTDVAVKDDPELQTWCREITEIGLQGAQDRGFPVSLQARDQVCHFVTMCIFTCTGQH ASVHLGQLDWYSWVPNAPCTMRLPPPTTKDATLETVMATLPNFHQASLQMSITWQLGRRQ PVMVAVGQHEEEYFSGPEPKAVLKKFREELAALDKEIEIRNAKLDMPYEYLRPSVVENSV AI |