| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 239 |
Name | ALOX12 |
Synonym | 12-LOX|12S-LOX|LOG12;arachidonate 12-lipoxygenase;ALOX12;arachidonate 12-lipoxygenase |
Definition | 12(S)-lipoxygenase|12S-lipoxygenase|arachidonate 12-lipoxygenase, 12S-type|lipoxin synthase 12-LO|platelet 12-LOX|platelet-type 12-lipoxygenase|platelet-type lipoxygenase 12 |
Position | 17p13.1 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Inflammation mediated by chemokine and cytokine signaling pathway;PANTHER;P00031 |
Pathway | Metabolic pathways;KEGG PATHWAY;hsa01100 |
Pathway | Arachidonic acid metabolism;KEGG PATHWAY;hsa00590 |
Disease | menopause;GAD |
Disease | Hypertension;FunDO |
Disease | PSYCH;GAD |
Disease | REPRODUCTION;GAD |
Disease | CARDIOVASCULAR;GAD |
Disease | bone density;GAD |
Disease | CANCER;GAD |
Disease | hypertension;GAD |
Disease | Cancer;FunDO |
Disease | METABOLIC;GAD |
Disease | bipolar disorder;GAD |
Disease | Bipolar disorder;FunDO |
Disease | Alzheimer's disease;FunDO |
Disease | colorectal cancer;GAD |
External Links | |
Links to Entrez Gene | 239 |
Links to all GeneRIF Items | 239 |
Links to iHOP | 239 |
Sequence Information | |
Nucleotide Sequence | >239 : length: 4038 TGATAAGAGCTCTAGTGAGAGGCTAGGCCTAGAGAGGGACATGGAGAAATAGCATGCGGA GAGGAACGGTAGAGGAGCAACGCTAACATTCAGTTGTAAATAATACAATCATAGCAGCTA ATACATAGAGGGACTACACGCCAAGCACTGTTCTCACTGTTTAGCCATATTCACTCATTT AGCATGCGCAGTAGCTTGAATCCGGTTTTTCAATTATTCATTCCCTCTCTCTGCACGTGG CCGTAGAGTACACTAGAGTGGGCAGAAAATAAGTCACAAAACAGCAAAGAAACAGTGCTT TTGGAAGTAGGTATGAGACAAACTCTTTTCTAGGCAAAAGTAACCCACGAAAATGTGTGT GGAAAGGCCAGATCCTACTATTAGGCAGGATGGGAATTTGAGCCATTTTATTTGGATATT ACAGAATGGGGTGACCCCAGAAAACTGGAAGAACTGGGGACCAGCAAATGGCCGACCTGC AGTCCTGAGCAGAGGATGTAGGCCAGAGTGGACCTAGAAGATAAGAAAGGGAATTGAATC CAGTAAGGGACAGACACTTTATTTTTTTATTTTTATTTATTTATTTATTTATTTTTGAGA TAGAGTCTGATCTGGAGGCTGGAAGGCGGGGCTAAAACTCCCACTCACTTACCTCTACCA ACAACTAGGCCACCAAGTCATTTCTGAGGACTGGCTCAAGAAAGCAGATTTAACTTACAC TGGCCTAGCCCAGGCCACCAGATGCATCCACGGAGATCCAAATGCATATAATCACTTGAA TCAAGATCTAGACAGGGACGCGTGCAGCAGGCTTCATCTGACTGATTCCTGACACGGGAG AGAAAGCCTAAGCTCCGAATCATCCTTCAATGTTTACAAAGGCCCTAAATAGCAGTGGGC TAATTGCTGTTCCTGGATTTCCAGGAGACCTGAGACCCATGAAGGAGCAGGAAAGAGCTT GGGGATAAAAAATTAATCTGGAACCTACTGGAGCGGAAGGGGCTGCACTCACCTGGAAAA GACAAAGTTCTTGGGAACTGGCCACGTAGGCCAGGTCCCTAAGCAATTCCATCCCGCACC CTAACACCCCGACTGGTGTTCCTGGGTCCCTAACATTGTCTGTACCCGCTTCGGAGGTTG GACAAAATGAGTTTTTCACTGCCCTGCCTCAGGCCTCTCTCAAAGGTCTGGCCCATGATA TTTGGTGTACATTGGGACCCCAGCGCCCAGATATTTGAAACGGGGTGGGGAGCGGGTGTT GAGCTGCTACATTTCCAGGTTCTAGGTACCCTGGGGAACCCCTGGTCGTTGACGGAAGCA CAGCGTTCAAGGGCGGCAGAGCTCAGGTACTGGAGGACACATGGGCCGCGCCGGGTCTAG CCGCGGGACATCCCCAGACCCCAGCACGGCCTCCCAGGCCGACCTTCCAGAAGCCGGCCC ACTGCCTTCCCCGGGTCCCAGCCCAGAAAAGCGGAGACCTTCCCCTCCGTTTGGAAGATG GACTCATCCCCTACTTCCTCCTGGCTCCCCAGAAGACCTGGAGACCTCGGGAAGTGTTCT CATCTATGTTCGCTCCAACCCGGGGGCTCAGGCCCACCTCGATCCCGCCTTCCCGGGAGG TCCAGGAAGGTCCCGCCGCACCCACCCCGTTGGCCTCACCCTGGCTCGGGCCCCTTTATC ATCCTGCAGCTACGCTCCGACCAGGAGGCACAGCCAGTCCCCACAGCCGGCTCTACCGCT CTGCTCGCAGGTTTGGGCTAGTCTGGGGCGGGGACTTGGGAGCGCCTAAAACTTGCGAGG AGGGCGGGGCCGCAGACCGGTCCTTTAAAGGTTGGAAGTGGCCCCGAGGCGCCGGCAGCC CTGGGCGGTCCCGGGAATCGCACAGGACCCGGCTCCCCTCGCCTAAGCTGCTGGGGGGCG CCATGGGCCGCTACCGCATCCGCGTGGCCACCGGGGCCTGGCTCTTCTCCGGGTCGTACA ACCGCGTGCAGCTTTGGCTGGTCGGGACGCGCGGGGAGGCGGAGCTGGAGCTGCAGCTGC GGCCCGCGCGGGGCGAGGAGGAGGAGTTTGATCATGACGTTGCAGAGGACTTGGGGCTCC TGCAGTTCGTGAGGCTGCGCAAGCACCACTGGCTGGTGGACGACGCGTGGTTCTGCGACC GCATCACGGTGCAGGGCCCTGGAGCCTGCGCGGAGGTGGCCTTCCCGTGCTACCGCTGGG TGCAGGGCGAGGACATCCTGAGCCTGCCCGAGGGCACCGCCCGCCTGCCAGGAGACAATG CTTTGGACATGTTCCAGAAGCATCGAGAGAAGGAACTGAAAGACAGACAGCAGATCTACT GCTGGGCCACCTGGAAGGAAGGGTTACCCCTGACCATCGCTGCAGACCGTAAGGATGATC TACCTCCAAATATGAGATTCCATGAGGAGAAGAGGCTGGACTTTGAATGGACACTGAAGG CAGGGCTAGTGCTGCCCTCGGGGATGGAAGAGCTTCAGGCTCAACTGGAGAAAGAACTTC AGAATGGTTCCCTGTTTGAAGCTGACTTCATCCTTCTGGATGGAATTCCAGCCAACGTGA TCCGAGGAGAGAAGCAATACCTGGCTGCCCCCCTCGTTATGCTGAAGATGGAGCCCAATG GGAAGCTGCAGCCCATGGTCATCCAGATTCAGCCTCCCAACCCCAGCTCTCCAACCCCAA CACTGTTCCTGCCCTCAGACCCCCCACTTGCCTGGCTCCTGGCAAAGTCCTGGGTCCGAA ATTCAGATTTCCAACTGCACGAGATCCAGTATCACTTGCTGAACACTCACCTGGTGGCTG AGGTCATCGCTGTCGCCACCATGCGGTGCCTCCCAGGACTGCACCCCATCTTCAAGTTCC TGATCCCCCATATCCGCTACACCATGGAAATCAACACCCGGGCCCGGACCCAACTCATCT CAGATGGAGGAATTTTTGATAAGGCAGTGAGCACAGGTGGAGGGGGCCATGTACAGTTGC TCCGTCGGGCGGCAGCTCAGCTGACCTACTGCTCCCTCTGTCCTCCTGACGACCTGGCTG ACCGGGGCCTGCTGGGACTCCCAGGTGCTCTCTATGCCCATGATGCTTTACGGCTCTGGG AGATCATTGCCAGGTATGTGGAGGGGATCGTCCACCTCTTCTACCAAAGGGATGACATAG TGAAGGGGGACCCTGAGCTGCAGGCCTGGTGTCGGGAGATCACGGAGGTGGGGCTGTGCC AGGCCCAGGACCGAGGTTTCCCTGTCTCCTTCCAGTCCCAGAGTCAACTCTGCCATTTCC TCACCATGTGCGTCTTCACGTGCACTGCCCAGCATGCCGCCATCAACCAGGGCCAGCTGG ACTGGTATGCCTGGGTCCCTAATGCTCCATGCACAATGCGGATGCCCCCACCCACCACCA AGGAAGATGTGACGATGGCCACAGTGATGGGGTCACTACCTGATGTCCGGCAGGCCTGTC TTCAAATGGCCATCTCATGGCATCTGAGTCGCCGCCAGCCAGACATGGTGCCTCTGGGGC ACCACAAAGAAAAATATTTCTCAGGCCCCAAGCCCAAAGCTGTGCTAAACCAATTCCGAA CAGATTTGGAAAAGCTGGAAAAGGAGATTACAGCCCGGAATGAGCAACTTGACTGGCCCT ATGAATATCTGAAGCCCAGCTGCATAGAGAACAGTGTCACCATCTGAGCCCTAGAGTGAC TCTACCTGCAAGATTTCACATCAGCTTTAGGACTGACATTTCTATCTTGAATTTCATGCT TTCCTAAAGTCTCTGCTGCTAAGGCTCTATTTCCTCCCCCAGTTAAACCCCCTACATTAG TATCCCACTAGCCCAGGGGAGCAGTAAACTTTCTCTGCAAAGACTAGATCCTTTTTTACG CTTTGCAGACCGCATAGTCACTGTCTCAACTACTCAGCTCTCCTGCTGCAGCATGAAGGC AGCCACAGACAACATGGAAATGAGTGTGACTATGTTCCAATAAAACTTTATGGACACTGA GATATGAATGTTACATCA |
Protein Sequence | >239 : length: 713 MFAPTRGLRPTSIPPSREVQEGPAAPTPLASPWLGPLYHPAATLRPGGTASPHSRLYRSA RRFGLVWGGDLGAPKTCEEGGAADRSFKGWKWPRGAGSPGRSRESHRTRLPSPKLLGGAM GRYRIRVATGAWLFSGSYNRVQLWLVGTRGEAELELQLRPARGEEEEFDHDVAEDLGLLQ FVRLRKHHWLVDDAWFCDRITVQGPGACAEVAFPCYRWVQGEDILSLPEGTARLPGDNAL DMFQKHREKELKDRQQIYCWATWKEGLPLTIAADRKDDLPPNMRFHEEKRLDFEWTLKAG LVLPSGMEELQAQLEKELQNGSLFEADFILLDGIPANVIRGEKQYLAAPLVMLKMEPNGK LQPMVIQIQPPNPSSPTPTLFLPSDPPLAWLLAKSWVRNSDFQLHEIQYHLLNTHLVAEV IAVATMRCLPGLHPIFKFLIPHIRYTMEINTRARTQLISDGGIFDKAVSTGGGGHVQLLR RAAAQLTYCSLCPPDDLADRGLLGLPGALYAHDALRLWEIIARYVEGIVHLFYQRDDIVK GDPELQAWCREITEVGLCQAQDRGFPVSFQSQSQLCHFLTMCVFTCTAQHAAINQGQLDW YAWVPNAPCTMRMPPPTTKEDVTMATVMGSLPDVRQACLQMAISWHLSRRQPDMVPLGHH KEKYFSGPKPKAVLNQFRTDLEKLEKEITARNEQLDWPYEYLKPSCIENSVTI |