| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 1978 |
Name | EIF4EBP1 |
Synonym | 4E-BP1|4EBP1|BP-1|PHAS-I;eukaryotic translation initiation factor 4E binding protein 1;EIF4EBP1;eukaryotic translation initiation factor 4E binding protein 1 |
Definition | eIF4E-binding protein 1|eukaryotic translation initiation factor 4E-binding protein 1|phosphorylated heat- and acid-stable protein regulated by insulin 1 |
Position | 8p12 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Release of eIF4E;PID Reactome;500965 |
Pathway | Insulin signaling pathway;KEGG PATHWAY;hsa04910 |
Pathway | Insulin Pathway;PID Curated;200012 |
Pathway | Signaling mediated by p38-alpha and p38-beta;PID Curated;200154 |
Pathway | Signaling by Insulin receptor;Reactome;REACT:498 |
Pathway | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met);PID Curated;200032 |
Pathway | ErbB signaling pathway;KEGG PATHWAY;hsa04012 |
Pathway | p53 pathway by glucose deprivation;PANTHER;P04397 |
Pathway | mtor signaling pathway;PID BioCarta;100101 |
Pathway | Gene Expression;Reactome;REACT:71 |
Pathway | Metabolism of proteins;Reactome;REACT:17015 |
Pathway | Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S;PID Reactome;500880 |
Pathway | mTOR signaling pathway;KEGG PATHWAY;hsa04150 |
Pathway | skeletal muscle hypertrophy is regulated via akt-mtor pathway;PID BioCarta;100137 |
Pathway | mTOR signaling pathway;PID Curated;200080 |
Pathway | regulation of eif-4e and p70s6 kinase;PID BioCarta;100178 |
Pathway | Acute myeloid leukemia;KEGG PATHWAY;hsa05221 |
Disease | Breast cancer;FunDO |
Disease | Alzheimer's disease;FunDO |
Disease | Prostate cancer;FunDO |
External Links | |
Links to Entrez Gene | 1978 |
Links to all GeneRIF Items | 1978 |
Links to iHOP | 1978 |
Sequence Information | |
Nucleotide Sequence | >1978 : length: 877 GGGGCGAGGCGGAGCGAGGCTGGAGGCGCGGGAGGGCAGCGAGAGGTTCGCGGGTGCAGC GCACAGGAGACCATGTCCGGGGGCAGCAGCTGCAGCCAGACCCCAAGCCGGGCCATCCCC GCCACTCGCCGGGTGGTGCTCGGCGACGGCGTGCAGCTCCCGCCCGGGGACTACAGCACG ACCCCCGGCGGCACGCTCTTCAGCACCACCCCGGGAGGTACCAGGATCATCTATGACCGG AAATTCCTGATGGAGTGTCGGAACTCACCTGTGACCAAAACACCCCCAAGGGATCTGCCC ACCATTCCGGGGGTCACCAGCCCTTCCAGTGATGAGCCCCCCATGGAAGCCAGCCAGAGC CACCTGCGCAATAGCCCAGAAGATAAGCGGGCGGGCGGTGAAGAGTCACAGTTTGAGATG GACATTTAAAGCACCAGCCATCGTGTGGAGCACTACCAAGGGGCCCCTCAGGGCCTTCCT GGGAGGAGTCCCACCAGCCAGGCCTTATGAAAGTGATCATACTGGGCAGGCGTTGGCGTG GGGTCGGACACCCCAGCCCTTTCTCCCTCACTCAGGGCACCTGCCCCCTCCTCTTCGTGA ACACCAGCAGATACCTCCTTGTGCCTCCACTGATGCAGGAGCTGCCACCCCAAGGGGAGT GACCCCTGCCAGCACACCCTGCAGCCAAGGGCCAGGAAGTGGACAAGAACGAACCCTTCC TTCCGAATGATCAGCAGTTCCAGCCCCTCGCTGCTGGGGGCGCAACCACCCCTTCCTTAG GTTGATGTGCTTGGGAAAGCTCCCTCCCCCTCCTTCCCCAAGAGAGGAAATAAAAGCCAC CTTCGCCCTAGGGCCAAGAAAAAAAAAAAAAAAAAAA |
Protein Sequence | >1978 : length: 118 MSGGSSCSQTPSRAIPATRRVVLGDGVQLPPGDYSTTPGGTLFSTTPGGTRIIYDRKFLM ECRNSPVTKTPPRDLPTIPGVTSPSSDEPPMEASQSHLRNSPEDKRAGGEESQFEMDI |