| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 1644 |
Name | DDC |
Synonym | AADC;dopa decarboxylase (aromatic L-amino acid decarboxylase);DDC;dopa decarboxylase (aromatic L-amino acid decarboxylase) |
Definition | aromatic-L-amino-acid decarboxylase |
Position | 7p12.2 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | 5-Hydroxytryptamine biosynthesis;PANTHER;P04371 |
Pathway | Hormone biosynthesis;Reactome;REACT:15314 |
Pathway | tryptophan degradation X (mammalian, via tryptamine);BioCyc;PWY-6307 |
Pathway | Tyrosine metabolism;KEGG PATHWAY;hsa00350 |
Pathway | Metabolic pathways;KEGG PATHWAY;hsa01100 |
Pathway | Metabolism of amino acids and derivatives;Reactome;REACT:13 |
Pathway | Phenylalanine metabolism;KEGG PATHWAY;hsa00360 |
Pathway | Synaptic Transmission;Reactome;REACT:13685 |
Pathway | Adrenaline and noradrenaline biosynthesis;PANTHER;P00001 |
Pathway | catecholamine biosynthesis;BioCyc;PWY66-301 |
Pathway | serotonin and melatonin biosynthesis;BioCyc;PWY-6030 |
Pathway | Histidine metabolism;KEGG PATHWAY;hsa00340 |
Pathway | Tryptophan metabolism;KEGG PATHWAY;hsa00380 |
Disease | Neuroblastoma;FunDO |
Disease | CHEMDEPENDENCY;GAD |
Disease | Aromatic L-amino acid decarboxylase deficiency;OMIM |
Disease | malaria;GAD |
Disease | Malaria;NHGRI |
Disease | CANCER;GAD |
Disease | Pancreas disease;FunDO |
Disease | nicotine dependence smoking behavior;GAD |
Disease | Schizophrenia;FunDO |
Disease | INFECTION;GAD |
Disease | Autistic disorder;FunDO |
Disease | Acute lymphoblastic leukemia (childhood);GAD |
Disease | Bipolar disorder;FunDO |
External Links | |
Links to Entrez Gene | 1644 |
Links to all GeneRIF Items | 1644 |
Links to iHOP | 1644 |
Sequence Information | |
Nucleotide Sequence | >1644 : length: 2090 GGCACATGTGGCTGGAAATGCAAGAAGAGGGAAACGTGTGGCTTGGAGTTTCAAGAAGAG TGACTGTCTCAGTGCCGAGTGCCTCAGCAGCTTCTCCACATGCTCTTCAGTCCCCAAAGT TGGAGAATCCCATCAAGGAGAGTAGCCCTGTAAGGAATTCGAATTTCCAGCATTTTTCAC CTCTGACAGAGCCCAGACACCATGAACGCAAGTGAATTCCGAAGGAGAGGGAAGGAGATG GTGGATTACGTGGCCAACTACATGGAAGGCATTGAGGGACGCCAGGTCTACCCTGACGTG GAGCCCGGGTACCTGCGGCCGCTGATCCCTGCCGCTGCCCCTCAGGAGCCAGACACGTTT GAGGACATCATCAACGACGTTGAGAAGATAATCATGCCTGGGGTGACGCACTGGCACAGC CCCTACTTCTTCGCCTACTTCCCCACTGCCAGCTCGTACCCGGCCATGCTTGCGGACATG CTGTGCGGGGCCATTGGCTGCATCGGCTTCTCCTGGGCGGCAAGCCCAGCATGCACAGAG CTGGAGACTGTGATGATGGACTGGCTCGGGAAGATGCTGGAACTACCAAAGGCATTTTTG AATGAGAAAGCTGGAGAAGGGGGAGGAGTGATCCAGGGAAGTGCCAGTGAAGCCACCCTG GTGGCCCTGCTGGCCGCTCGGACCAAAGTGATCCATCGGCTGCAGGCAGCGTCCCCAGAG CTCACACAGGCCGCTATCATGGAGAAGCTGGTGGCTTACTCATCCGATCAGGCACACTCC TCAGTGGAAAGAGCTGGGTTAATTGGTGGAGTGAAATTAAAAGCCATCCCCTCAGATGGC AACTTCGCCATGCGTGCGTCTGCCCTGCAGGAAGCCCTGGAGAGAGACAAAGCGGCTGGC CTGATTCCTTTCTTTATGGTTGCCACCCTGGGGACCACAACATGCTGCTCCTTTGACAAT CTCTTAGAAGTCGGTCCTATCTGCAACAAGGAAGACATATGGCTGCACGTTGATGCAGCC TACGCAGGCAGTGCATTCATCTGCCCTGAGTTCCGGCACCTTCTGAATGGAGTGGAGTTT GCAGATTCATTCAACTTTAATCCCCACAAATGGCTATTGGTGAATTTTGACTGTTCTGCC ATGTGGGTGAAAAAGAGAACAGACTTAACGGGAGCCTTTAGACTGGACCCCACTTACCTG AAGCACAGCCATCAGGATTCAGGGCTTATCACTGACTACCGGCATTGGCAGATACCACTG GGCAGAAGATTTCGCTCTTTGAAAATGTGGTTTGTATTTAGGATGTATGGAGTCAAAGGA CTGCAGGCTTATATCCGCAAGCATGTCCAGCTGTCCCATGAGTTTGAGTCACTGGTGCGC CAGGATCCCCGCTTTGAAATCTGTGTGGAAGTCATTCTGGGGCTTGTCTGCTTTCGGCTA AAGGGTTCCAACAAAGTGAATGAAGCTCTTCTGCAAAGAATAAACAGTGCCAAAAAAATC CACTTGGTTCCATGTCACCTCAGGGACAAGTTTGTCCTGCGCTTTGCCATCTGTTCTCGC ACGGTGGAATCTGCCCATGTGCAGCGGGCCTGGGAACACATCAAAGAGCTGGCGGCCGAC GTGCTGCGAGCAGAGAGGGAGTAGGAGTGAAGCCAGCTGCAGGAATCAAAAATTGAAGAG AGATATATCTGAAAACTGGAATAAGAAGCAAATAAATATCATCCTGCCTTCATGGAACTC AGCTGTCTGTGGCTTCCCATGTCTTTCTCCAAAGTTATCCAGAGGGTTGTGATTTTGTCT GCTTAGTATCTCATCAACAAAGAAATATTATTTGCTAATTAAAAAGTTAATCTTCATGGC CATAGCTTTTATTCATTAGCTGTGATTTTTGTTGATTAAAACATTATAGATTTTCATGTT CTTGCAGTCATCAGAAGTGGTAGGAAAGCCTCACTGATATATTTTCCAGGGCAATCAATG TTCACGCAACTTGAAATTATATCTGTGGTCTTCAAATTGTCTTTTGTCATGTGGCTAAAT GCCTAATAAACAATTCAAGTGAAATACTAAAAAAAAAAAAAAAAAAAAAA |
Protein Sequence | >1644 : length: 480 MNASEFRRRGKEMVDYVANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDV EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD WLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIM EKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMV ATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFN PHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSL KMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKVN EALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAADVLRAERE |