| General information | Literature | Expression | Regulation | Mutation | Homolog | Interaction |
Basic Information | |
|---|---|
Gene ID | 1200 |
Name | TPP1 |
Synonym | CLN2|GIG1|LPIC|SCAR7|TPP-1;tripeptidyl peptidase I;TPP1;tripeptidyl peptidase I |
Definition | cell growth-inhibiting gene 1 protein|growth-inhibiting protein 1|lysosomal pepstatin insensitive protease|tripeptidyl aminopeptidase|tripeptidyl-peptidase 1 |
Position | 11p15 |
Gene Type | protein-coding |
Pathways and Diseases | |
Pathway | Activation of Chaperones by IRE1alpha;PID Reactome;500131 |
Pathway | Diabetes pathways;Reactome;REACT:15380 |
Pathway | Lysosome;KEGG PATHWAY;hsa04142 |
Disease | reduced cerebrospinal fluid pterins;GAD |
Disease | Genetic disorders;KEGG DISEASE |
Disease | Lysosomal storage disease;FunDO |
Disease | Rabies;FunDO |
Disease | Neuronal ceroid lipofuscinosis;KEGG DISEASE;H00149 |
Disease | Lysosomal storage diseases;KEGG DISEASE |
Disease | Ceroid-lipofuscinosis, neuronal 2, classic late infantile;OMIM |
Disease | Neoplasm metastasis;FunDO |
External Links | |
Links to Entrez Gene | 1200 |
Links to all GeneRIF Items | 1200 |
Links to iHOP | 1200 |
Sequence Information | |
Nucleotide Sequence | >1200 : length: 3540 GGTGGTGGAATATAGAGCTCATGTGATCCGTCACATGACAGCAGATCCGCGGAAGGGCAG AATGGGACTCCAAGCCTGCCTCCTAGGGCTCTTTGCCCTCATCCTCTCTGGCAAATGCAG TTACAGCCCGGAGCCCGACCAGCGGAGGACGCTGCCCCCAGGCTGGGTGTCCCTGGGCCG TGCGGACCCTGAGGAAGAGCTGAGTCTCACCTTTGCCCTGAGACAGCAGAATGTGGAAAG ACTCTCGGAGCTGGTGCAGGCTGTGTCGGATCCCAGCTCTCCTCAATACGGAAAATACCT GACCCTAGAGAATGTGGCTGATCTGGTGAGGCCATCCCCACTGACCCTCCACACGGTGCA AAAATGGCTCTTGGCAGCCGGAGCCCAGAAGTGCCATTCTGTGATCACACAGGACTTTCT GACTTGCTGGCTGAGCATCCGACAAGCAGAGCTGCTGCTCCCTGGGGCTGAGTTTCATCA CTATGTGGGAGGACCTACGGAAACCCATGTTGTAAGGTCCCCACATCCCTACCAGCTTCC ACAGGCCTTGGCCCCCCATGTGGACTTTGTGGGGGGACTGCACCGTTTTCCCCCAACATC ATCCCTGAGGCAACGTCCTGAGCCGCAGGTGACAGGGACTGTAGGCCTGCATCTGGGGGT AACCCCCTCTGTGATCCGTAAGCGATACAACTTGACCTCACAAGACGTGGGCTCTGGCAC CAGCAATAACAGCCAAGCCTGTGCCCAGTTCCTGGAGCAGTATTTCCATGACTCAGACCT GGCTCAGTTCATGCGCCTCTTCGGTGGCAACTTTGCACATCAGGCATCAGTAGCCCGTGT GGTTGGACAACAGGGCCGGGGCCGGGCCGGGATTGAGGCCAGTCTAGATGTGCAGTACCT GATGAGTGCTGGTGCCAACATCTCCACCTGGGTCTACAGTAGCCCTGGCCGGCATGAGGG ACAGGAGCCCTTCCTGCAGTGGCTCATGCTGCTCAGTAATGAGTCAGCCCTGCCACATGT GCATACTGTGAGCTATGGAGATGATGAGGACTCCCTCAGCAGCGCCTACATCCAGCGGGT CAACACTGAGCTCATGAAGGCTGCCGCTCGGGGTCTCACCCTGCTCTTCGCCTCAGGTGA CAGTGGGGCCGGGTGTTGGTCTGTCTCTGGAAGACACCAGTTCCGCCCTACCTTCCCTGC CTCCAGCCCCTATGTCACCACAGTGGGAGGCACATCCTTCCAGGAACCTTTCCTCATCAC AAATGAAATTGTTGACTATATCAGTGGTGGTGGCTTCAGCAATGTGTTCCCACGGCCTTC ATACCAGGAGGAAGCTGTAACGAAGTTCCTGAGCTCTAGCCCCCACCTGCCACCATCCAG TTACTTCAATGCCAGTGGCCGTGCCTACCCAGATGTGGCTGCACTTTCTGATGGCTACTG GGTGGTCAGCAACAGAGTGCCCATTCCATGGGTGTCCGGAACCTCGGCCTCTACTCCAGT GTTTGGGGGGATCCTATCCTTGATCAATGAGCACAGGATCCTTAGTGGCCGCCCCCCTCT TGGCTTTCTCAACCCAAGGCTCTACCAGCAGCATGGGGCAGGACTCTTTGATGTAACCCG TGGCTGCCATGAGTCCTGTCTGGATGAAGAGGTAGAGGGCCAGGGTTTCTGCTCTGGTCC TGGCTGGGATCCTGTAACAGGCTGGGGAACACCCAACTTCCCAGCTTTGCTGAAGACTCT ACTCAACCCCTGACCCTTTCCTATCAGGAGAGATGGCTTGTCCCCTGCCCTGAAGCTGGC AGTTCAGTCCCTTATTCTGCCCTGTTGGAAGCCCTGCTGAACCCTCAACTATTGACTGCT GCAGACAGCTTATCTCCCTAACCCTGAAATGCTGTGAGCTTGACTTGACTCCCAACCCTA CCATGCTCCATCATACTCAGGTCTCCCTACTCCTGCCTTAGATTCCTCAATAAGATGCTG TAACTAGCATTTTTTGAATGCCTCTCCCTCCGCATCTCATCTTTCTCTTTTCAATCAGGC TTTTCCAAAGGGTTGTATACAGACTCTGTGCACTATTTCACTTGATATTCATTCCCCAAT TCACTGCAAGGAGACCTCTACTGTCACCGTTTACTCTTTCCTACCCTGACATCCAGAAAC AATGGCCTCCAGTGCATACTTCTCAATCTTTGCTTTATGGCCTTTCCATCATAGTTGCCC ACTCCCTCTCCTTACTTAGCTTCCAGGTCTTAACTTCTCTGACTACTCTTGTCTTCCTCT CTCATCAATTTCTGCTTCTTCATGGAATGCTGACCTTCATTGCTCCATTTGTAGATTTTT GCTCTTCTCAGTTTACTCATTGTCCCCTGGAACAAATCACTGACATCTACAACCATTACC ATCTCACTAAATAAGACTTTCTATCCAATAATGATTGATACCTCAAATGTAAGATGCGTG ATACTCAACATTTCATCGTCCACCTTCCCAACCCCAAACAATTCCATCTCGTTTCTTCTT GGTAAATGATGCTATGCTTTTTCCAACCAAGCCAGAAACCTGTGTCATCTTTTCACCCCA CCTTCAATCAACAAGTCCTCAATCAACAAGTCCTACTGACTGCACATCTTAAATATATCT TTATCAGTCCACAAGTCCTTCCAATTATATTTCCCAAGTATATCTAGAACTTATCCACTT ATATCCCCACTGCTACTACCTTAGTTTAGGGCTATATTCTCTTGAAAAAAAGTGTCCTTA CTTCCTGCCAATCCCCAAGTCATCTTCCAGAGTAAAATGCAAATCCCATCAGGCCACTTG GATGAAAACCCTTCAAGGATTACTGGATAGAATTCAGGCTTTCCCCTCCAGCCCCCAATC ATAGCTCACAAACCTTCCTTGCTATTTGTTCTTAAGTAAAAAATCATTTTTCCTCCTCCC TCCCCAAACCCCAAGGAACTCTCACTCTTGCTCAAGCTGTTCCGTCCCCTTACCACCCCT GATACAACTGCCAGGTTAATTTCCAGAATTCTTGCAAGACTCAGTTCAGAAGTCACCTTC TTTCGTGAATGTTTTGATTCCCTGAGGCTACTTTATTTTGGTATGGCTGAAAAATCCTAG ATTTTCTAAACAAAACCTGTTTGAATCTTGGTTCTGATATGGACTAGGAGAGAGACTGGG TCAAGTAAGCTTATCTCCCTGAGGCTGTTTCCTCGTCTGTTAAGTGTGAATATCAATACC TGCCTTTCATAATCACCAGGGAATAAAGTGGAATAATGTTGATAACAGTGCTTGGCACCT GGAAGTAGGTGGCAGATGTTAACGCCCTTCCTCCCTTGCACTGCGCCCCCTGTGCCTACC TCTAGCATTGTAACGACCACGTAGTATTGAAATGGCCAGTTTACTTGTCTGCCTTCCTTT CCAAGACCGTTGGTGCCTAGAGGACTAGAATCGTGTCCTATTTAACTTTGTGTTCCCAGG TCCTAGCTCAGGAGTTGGCAAATAAGAATTAAATGTCTGCTACACCGAAAACCAAAAAAA |
Protein Sequence | >1200 : length: 563 MGLQACLLGLFALILSGKCSYSPEPDQRRTLPPGWVSLGRADPEEELSLTFALRQQNVER LSELVQAVSDPSSPQYGKYLTLENVADLVRPSPLTLHTVQKWLLAAGAQKCHSVITQDFL TCWLSIRQAELLLPGAEFHHYVGGPTETHVVRSPHPYQLPQALAPHVDFVGGLHRFPPTS SLRQRPEPQVTGTVGLHLGVTPSVIRKRYNLTSQDVGSGTSNNSQACAQFLEQYFHDSDL AQFMRLFGGNFAHQASVARVVGQQGRGRAGIEASLDVQYLMSAGANISTWVYSSPGRHEG QEPFLQWLMLLSNESALPHVHTVSYGDDEDSLSSAYIQRVNTELMKAAARGLTLLFASGD SGAGCWSVSGRHQFRPTFPASSPYVTTVGGTSFQEPFLITNEIVDYISGGGFSNVFPRPS YQEEAVTKFLSSSPHLPPSSYFNASGRAYPDVAALSDGYWVVSNRVPIPWVSGTSASTPV FGGILSLINEHRILSGRPPLGFLNPRLYQQHGAGLFDVTRGCHESCLDEEVEGQGFCSGP GWDPVTGWGTPNFPALLKTLLNP |